Standout Papers

Evidence that metformin exerts its anti-diabetic effects through in... 1990 2026 2002 2014 1.7k
  1. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain (2000)
    E. Doran, Andrew P. Halestrap et al. Biochemical Journal
  2. Role of calcium ions in regulation of mammalian intramitochondrial metabolism (1990)
    J G McCormack, Andrew P. Halestrap et al. Physiological Reviews
  3. The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation (1999)
    Andrew P. Halestrap, Nigel T. Price Biochemical Journal
  4. Mitochondrial permeability transition pore opening during myocardial reperfusion—a target for cardioprotection (2003)
    Andrew P. Halestrap Cardiovascular Research
  5. The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond (2004)
    Andrew P. Halestrap, David Meredith Pflügers Archiv - European Journal of Physiology
  6. What is the mitochondrial permeability transition pore? (2009)
    Andrew P. Halestrap Journal of Molecular and Cellular Cardiology
  7. The Plasma Membrane Lactate Transporter MCT4, but Not MCT1, Is Up-regulated by Hypoxia through a HIF-1α-dependent Mechanism (2006)
    Andrew Davies, Andrew P. Halestrap et al. Journal of Biological Chemistry
  8. Inhibition of Ca2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine nucleotide translocase (1990)
    Andrew P. Halestrap, A M Davidson Biochemical Journal
  9. The permeability transition pore complex: another view (2002)
    Andrew P. Halestrap, Gavin P. McStay et al. Biochimie
  10. Transport of lactate and other monocarboxylates across mammalian plasma membranes (1993)
    R C Poole, Andrew P. Halestrap American Journal of Physiology-Cell Physiology
  11. CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression (2000)
    Peter Kirk, Marieangela C. Wilson et al. The EMBO Journal
  12. The monocarboxylate transporter family—Role and regulation (2011)
    Andrew P. Halestrap, Marieangela C. Wilson IUBMB Life
  13. The SLC16 gene family – Structure, role and regulation in health and disease (2013)
    Andrew P. Halestrap Molecular Aspects of Medicine
  14. Identification of Monocarboxylate Transporter 8 as a Specific Thyroid Hormone Transporter (2003)
    Edith C. H. Friesema, Jocelyn E. Manning Fox et al. Journal of Biological Chemistry
  15. The monocarboxylate transporter family—Structure and functional characterization (2011)
    Andrew P. Halestrap IUBMB Life
  16. Oxidative Stress, Thiol Reagents, and Membrane Potential Modulate the Mitochondrial Permeability Transition by Affecting Nucleotide Binding to the Adenine Nucleotide Translocase (1997)
    Andrew P. Halestrap, Cathal P. Connern et al. Journal of Biological Chemistry
  17. Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation (2004)
    Edith C. H. Friesema, Annette Grueters et al. The Lancet
  18. Protection by Cyclosporin A of Ischemia/Reperfusion-Induced Damage in Isolated Rat Hearts (1993)
    Elinor J. Griffiths, Andrew P. Halestrap Journal of Molecular and Cellular Cardiology
  19. The mitochondrial pyruvate carrier. Kinetics and specificity for substrates and inhibitors (1975)
    Andrew P. Halestrap Biochemical Journal
  20. Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by α-cyano-4-hydroxycinnamate (Short Communication) (1974)
    Andrew P. Halestrap, Richard M. Denton Biochemical Journal
  21. Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions (2023)
    Paolo Bernardi, Christoph Gerle et al. Cell Death and Differentiation

Immediate Impact

5 by Nobel laureates 33 from Science/Nature 109 standout
Sub-graph 1 of 18

Citing Papers

A break in mitochondrial endosymbiosis as a basis for inflammatory diseases
2024 StandoutNature
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid
2021 StandoutNature
14 intermediate papers

Works of Andrew P. Halestrap being referenced

The monocarboxylate transporter family—Role and regulation
2011 Standout
The Kinetics, Substrate, and Inhibitor Specificity of the Monocarboxylate (Lactate) Transporter of Rat Liver Cells Determined Using the Fluorescent Intracellular pH Indicator, 2′,7′-Bis(carboxyethyl)-5(6)-carboxyfluorescein
1996
and 31 more

Author Peers

Author Last Decade Papers Cites
Andrew P. Halestrap 22215 6544 5649 225 34.7k
John J. Lemasters 15404 3246 4329 439 32.2k
Richard J. Youle 43318 7432 2046 238 61.8k
Paul T. Schumacker 14838 5267 2608 210 28.9k
Junichi Sadoshima 20563 5721 3211 368 36.0k
Victor Darley‐Usmar 14668 9851 2911 368 32.2k
Kathy K. Griendling 16883 16992 2831 228 45.3k
Paolo Pinton 22730 4000 1491 385 33.4k
Daria Mochly‐Rosen 17008 3857 4360 318 25.6k
Pak H. Chan 15167 5190 2500 309 32.0k
Vadivel Ganapathy 17090 3853 1244 500 33.2k

All Works

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