Zhenning He

1.4k total citations · 1 hit paper
23 papers, 1.0k citations indexed

About

Zhenning He is a scholar working on Molecular Biology, Genetics and Genetics. According to data from OpenAlex, Zhenning He has authored 23 papers receiving a total of 1.0k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 10 papers in Genetics and 8 papers in Genetics. Recurrent topics in Zhenning He's work include Virus-based gene therapy research (10 papers), Hemoglobinopathies and Related Disorders (8 papers) and CRISPR and Genetic Engineering (7 papers). Zhenning He is often cited by papers focused on Virus-based gene therapy research (10 papers), Hemoglobinopathies and Related Disorders (8 papers) and CRISPR and Genetic Engineering (7 papers). Zhenning He collaborates with scholars based in United States, China and Taiwan. Zhenning He's co-authors include Lili Wang, James M. Wilson, Peter Bell, John White, Hongwei Yu, Deirdre McMenamin, Yang Yang, Mark L. Batshaw, Hiroki Morizono and Janice Russell and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nature Medicine and Blood.

In The Last Decade

Zhenning He

23 papers receiving 1.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice

2016 433 citations Yang Yang, Lili Wang et al. Nature Biotechnology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Zhenning He United States	14	826	470	98	84	78	23	1.0k
Deirdre McMenamin United States	8	688 0.8×	441 0.9×	61 0.6×	90 1.1×	67 0.9×	14	816
John White United States	6	576 0.7×	308 0.7×	54 0.6×	48 0.6×	41 0.5×	9	659
Qiushi Tang United States	18	647 0.8×	544 1.2×	83 0.8×	185 2.2×	121 1.6×	34	1.0k
M. Kyle Cromer United States	11	992 1.2×	443 0.9×	68 0.7×	255 3.0×	47 0.6×	17	1.2k
Jenny A. Greig United States	18	1.0k 1.2×	889 1.9×	150 1.5×	363 4.3×	224 2.9×	37	1.6k
Naif A. M. Almontashiri Saudi Arabia	14	444 0.5×	105 0.2×	52 0.5×	38 0.5×	160 2.1×	43	746
Samuel Lessard United States	7	651 0.8×	201 0.4×	32 0.3×	42 0.5×	33 0.4×	19	911
Phillip A. Doerfler United States	12	566 0.7×	272 0.6×	33 0.3×	103 1.2×	29 0.4×	20	770
Sandeep K. Botla Germany	5	912 1.1×	258 0.5×	32 0.3×	176 2.1×	20 0.3×	5	1.0k
Cherie L. Ramirez United States	10	1.4k 1.7×	308 0.7×	41 0.4×	131 1.6×	29 0.4×	13	1.6k

Countries citing papers authored by Zhenning He

Since Specialization

Citations

This map shows the geographic impact of Zhenning He's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zhenning He with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zhenning He more than expected).

Fields of papers citing papers by Zhenning He

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zhenning He. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zhenning He. The network helps show where Zhenning He may publish in the future.

Co-authorship network of co-authors of Zhenning He

This figure shows the co-authorship network connecting the top 25 collaborators of Zhenning He. A scholar is included among the top collaborators of Zhenning He based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Zhenning He. Zhenning He is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Zhan, Jinhua, Yijia Chen, Yuying Liu, et al.. (2025). IDO1-mediated AhR activation up-regulates pentose phosphate pathway via NRF2 to inhibit ferroptosis in lung cancer. Biochemical Pharmacology. 236. 116913–116913. 2 indexed citations

Greig, Jenny A., Camilo Breton, Jason Lamontagne, et al.. (2023). Integrated vector genomes may contribute to long-term expression in primate liver after AAV administration. Nature Biotechnology. 42(8). 1232–1242. 73 indexed citations

Wang, Lili, Claude C. Warzecha, Jessica A. Chichester, et al.. (2022). Prednisolone reduces the interferon response to AAV in cynomolgus macaques and may increase liver gene expression. Molecular Therapy — Methods & Clinical Development. 24. 292–305. 19 indexed citations

Wang, Lili, Camilo Breton, Claude C. Warzecha, et al.. (2021). Long-term stable reduction of low-density lipoprotein in nonhuman primates following in vivo genome editing of PCSK9. Molecular Therapy. 29(6). 2019–2029. 48 indexed citations

Wang, Lili, Ilayaraja Muthuramu, Suryanarayan Somanathan, et al.. (2021). Developing a second-generation clinical candidate AAV vector for gene therapy of familial hypercholesterolemia. Molecular Therapy — Methods & Clinical Development. 22. 1–10. 19 indexed citations

Wang, Lili, Yang Yang, Camilo Breton, et al.. (2020). A mutation-independent CRISPR-Cas9–mediated gene targeting approach to treat a murine model of ornithine transcarbamylase deficiency. Science Advances. 6(7). eaax5701–eaax5701. 53 indexed citations

Wang, Lili, Jeff Smith, Camilo Breton, et al.. (2018). Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol. Nature Biotechnology. 36(8). 717–725. 89 indexed citations

Wang, Lili, Peter Bell, Hiroki Morizono, et al.. (2017). AAV gene therapy corrects OTC deficiency and prevents liver fibrosis in aged OTC-knock out heterozygous mice. Molecular Genetics and Metabolism. 120(4). 299–305. 38 indexed citations

Bell, Peter, Lili Wang, Shu‐Jen Chen, et al.. (2016). Effects of Self-Complementarity, Codon Optimization, Transgene, and Dose on Liver Transduction with AAV8. Human Gene Therapy Methods. 27(6). 228–237. 21 indexed citations

10.

Yang, Yang, Lili Wang, Peter Bell, et al.. (2016). A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice. Nature Biotechnology. 34(3). 334–338. 433 indexed citations breakdown →

11.

Wang, Lili, Peter Bell, Suryanarayan Somanathan, et al.. (2015). Comparative Study of Liver Gene Transfer With AAV Vectors Based on Natural and Engineered AAV Capsids. Molecular Therapy. 23(12). 1877–1887. 76 indexed citations

12.

He, Zhenning, et al.. (2014). Structural determinants of human ζ-globin mRNA stability. Journal of Hematology & Oncology. 7(1). 35–35. 2 indexed citations

13.

Safo, Martin K., Tzu‐Ping Ko, Osheiza Abdulmalik, et al.. (2013). Structure of fully liganded Hb ζ₂β₂^strapped in a tense conformation. Acta Crystallographica Section D Biological Crystallography. 69(10). 2061–2071. 5 indexed citations

14.

He, Zhenning & Janice Russell. (2006). Dynamic posttranscriptional regulation of ϵ-globin gene expression in vivo. Blood. 109(2). 795–801. 5 indexed citations

15.

He, Zhenning & Janice Russell. (2004). Effect of ζ-globin substitution on the O2-transport properties of Hb S in vitro and in vivo. Biochemical and Biophysical Research Communications. 325(4). 1376–1382. 10 indexed citations

16.

He, Zhenning & Janice Russell. (2004). Antisickling effects of an endogenous human α-like globin. Nature Medicine. 10(4). 365–367. 14 indexed citations

17.

Ertl, Hildegund C.J., Susanna Pasquini, Zhenning He, et al.. (2003). Genetic Adjuvants. Humana Press eBooks. 29. 251–260. 1 indexed citations

18.

He, Zhenning & Janice Russell. (2002). A High-Throughput Microplate Method for Assessing Aggregation of Deoxygenated Hemoglobin S Heterotetramers in Vitro. Analytical Biochemistry. 306(2). 349–352. 4 indexed citations

19.

He, Zhenning & Janice Russell. (2002). A human embryonic hemoglobin inhibits Hb S polymerization in vitro and restores a normal phenotype to mouse models of sickle cell disease. Proceedings of the National Academy of Sciences. 99(16). 10635–10640. 13 indexed citations

20.

He, Zhenning, Lurong Lian, Toshio Asakura, & Janice Russell. (2000). Functional effects of replacing human α‐ and β‐globins with their embryonic globin homologues in defined haemoglobin heterotetramers. British Journal of Haematology. 109(4). 882–890. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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