Yu Chen

23.0k total citations · 6 hit papers
455 papers, 17.6k citations indexed

About

Yu Chen is a scholar working on Molecular Biology, Computational Theory and Mathematics and Organic Chemistry. According to data from OpenAlex, Yu Chen has authored 455 papers receiving a total of 17.6k indexed citations (citations by other indexed papers that have themselves been cited), including 240 papers in Molecular Biology, 131 papers in Computational Theory and Mathematics and 46 papers in Organic Chemistry. Recurrent topics in Yu Chen's work include Computational Drug Discovery Methods (130 papers), Protein Structure and Dynamics (41 papers) and Machine Learning in Bioinformatics (37 papers). Yu Chen is often cited by papers focused on Computational Drug Discovery Methods (130 papers), Protein Structure and Dynamics (41 papers) and Machine Learning in Bioinformatics (37 papers). Yu Chen collaborates with scholars based in China, Singapore and United States. Yu Chen's co-authors include Feng Zhu, Lianyi Han, Chun Wei Yap, Choong Yong Ung, Qin Chu, Weiwei Xue, Ying Xue, Chunyan Tan, Yinghong Li and Lin Tao and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Physical Review Letters and Nucleic Acids Research.

In The Last Decade

Yu Chen

424 papers receiving 17.2k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mechanisms of drug combinations: interaction and network perspectives

2009 759 citations Feng Zhu, Yu Chen et al. profile →
Therapeutic target database 2020: enriched resource for facilitating research and early development of targeted therapeutics

2019 651 citations Ying Tan, Qin Chu et al. Nucleic Acids Research profile →
Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics

2017 418 citations Yinghong Li, Peng Zhang et al. Nucleic Acids Research profile →
Therapeutic target database update 2022: facilitating drug discovery with enriched comparative data of targeted agents

2021 417 citations Yintao Zhang, Feng Zhu et al. Nucleic Acids Research profile →
Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery

2011 401 citations Feng Zhu, Qin Chu et al. Nucleic Acids Research profile →
TTD: Therapeutic Target Database describing target druggability information

2023 289 citations Yintao Zhang, Shanshan Wang et al. Nucleic Acids Research profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Yu Chen	10.0k	5.3k	1.8k	1.5k	1.5k	455	17.6k
Tudor I. Oprea	9.4k 0.9×	6.6k 1.2×	1.4k 0.8×	2.3k 1.5×	1.9k 1.3×	244	18.6k
Evan Bolton	7.3k 0.7×	5.1k 1.0×	1.3k 0.7×	1.1k 0.8×	1.4k 1.0×	71	14.6k
Benjamin A. Shoemaker	8.3k 0.8×	4.9k 0.9×	1.2k 0.7×	1.0k 0.7×	1.3k 0.9×	38	14.7k
Andrew L. Hopkins	9.1k 0.9×	5.0k 0.9×	1.4k 0.8×	1.9k 1.3×	1.4k 1.0×	63	14.2k
Aiping Lü	10.6k 1.1×	2.8k 0.5×	2.2k 1.2×	1.2k 0.8×	1.8k 1.2×	549	20.7k
Sunghwan Kim	6.0k 0.6×	4.3k 0.8×	1.1k 0.6×	1.2k 0.8×	1.2k 0.8×	139	13.2k
John P. Overington	11.7k 1.2×	6.9k 1.3×	940 0.5×	1.5k 1.0×	1.6k 1.1×	97	16.7k
Luhua Lai	9.3k 0.9×	5.2k 1.0×	810 0.5×	2.2k 1.5×	1.1k 0.8×	352	15.2k
Paul Thiessen	6.0k 0.6×	4.3k 0.8×	1.1k 0.6×	1.1k 0.8×	1.2k 0.8×	38	12.8k

Countries citing papers authored by Yu Chen

Since Specialization

Citations

This map shows the geographic impact of Yu Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yu Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yu Chen more than expected).

Fields of papers citing papers by Yu Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yu Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yu Chen. The network helps show where Yu Chen may publish in the future.

Co-authorship network of co-authors of Yu Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Yu Chen. A scholar is included among the top collaborators of Yu Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yu Chen. Yu Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Jiang, Jie, et al.. (2025). A study on the balance ability and plantar pressure of sarcopenia patients in different standing postures. Gait & Posture. 118. 51–60. 1 indexed citations

Chen, Yu. (2024). Music Psychology and its Integration in Middle School Music Education in China. Asian Journal of Education and Social Studies. 50(1). 105–113. 1 indexed citations

Chen, Yu, Junren Chen, Chen Sun, et al.. (2024). SIRT1 activation by Ligustrazine ameliorates migraine via the paracrine interaction of microglia and neurons. Phytomedicine. 135. 156069–156069. 8 indexed citations

Xu, Ziye, Lingchao Chen, Xin Lin, et al.. (2024). Single Nucleus Total RNA Sequencing of Formalin‐Fixed Paraffin‐Embedded Gliomas. Small Methods. 8(10). e2301801–e2301801. 2 indexed citations

Wang, Peng, et al.. (2024). Wireless Remote-Monitoring Technology for Wind-Induced Galloping and Vibration of Transmission Lines. Electronics. 13(23). 4630–4630. 1 indexed citations

Zhang, Yintao, Li Teng, Yimiao Zhu, et al.. (2024). SubCELL: the landscape of subcellular compartment-specific molecular interactions. Nucleic Acids Research. 53(D1). D738–D747. 2 indexed citations

Zhang, Zhuyun, Yu Chen, Zhihui Liu, et al.. (2024). Emerging therapeutic strategies targeting extracellular histones for critical and inflammatory diseases: an updated narrative review. Frontiers in Immunology. 15. 1438984–1438984. 7 indexed citations

Chen, Yu, et al.. (2024). TRF‐16 Inhibits Lung Cancer Progression by Hindering the N6‐Methyladenosine Modification of CPT1A mRNA. Journal of Cellular and Molecular Medicine. 28(24). e70291–e70291. 3 indexed citations

Zhao, Huan, et al.. (2024). Adenoid cystic carcinoma of trachea mimicking a thyroid follicular tumor: A case report and literature review. SHILAP Revista de lepidopterología. 19(12). 5653–5657.

10.

Chen, Yu, et al.. (2024). Mixed Variable Parameter Energy Storage-Assisted Frequency Support Strategy. Electronics. 13(8). 1450–1450.

11.

Xiang, Pingping, Xiaoyang Qu, Yu Chen, et al.. (2024). Investigating the mechanism and efficacy material basis of Xiehuo Xiaoying decoction for treating Graves' disease via thyroid cell apoptosis based on proteomics and molecular docking techniques. Journal of Ethnopharmacology. 324. 117753–117753. 3 indexed citations

12.

Liu, Yu, Zhi‐Hua Li, Qiang Zhang, et al.. (2024). Posphoproteomics profiling reveals the regulatory role of a phosphorylated protein PvFBA1 in cadmium tolerance in seashore paspalum. Ecotoxicology and Environmental Safety. 286. 117220–117220. 1 indexed citations

13.

Chen, Yu, et al.. (2024). Rogue wave patterns of two-component nonlinear Schrödinger equation coupled to the Boussinesq equation. Communications in Nonlinear Science and Numerical Simulation. 140. 108406–108406.

14.

Huang, Yuanfang, et al.. (2024). Raman spectroscopic deep learning with signal aggregated representations for enhanced cell phenotype and signature identification. PNAS Nexus. 3(8). pgae268–pgae268. 4 indexed citations

15.

Chen, Yu, et al.. (2023). An Emotional Design Model for Future Smart Product Based on Grounded Theory. Systems. 11(7). 377–377. 7 indexed citations

16.

Shen, Wan Xiang, Xian Zeng, Feng Zhu, et al.. (2021). Out-of-the-box deep learning prediction of pharmaceutical properties by broadly learned knowledge-based molecular representations. Nature Machine Intelligence. 3(4). 334–343. 101 indexed citations

17.

Yang, Hong, Yinghong Li, Weiwei Xue, et al.. (2018). Assessing the Performances of Protein Function Prediction Algorithms from the Perspectives of Identification Accuracy and False Discovery Rate. International Journal of Molecular Sciences. 19(1). 183–183. 29 indexed citations

18.

Li, Yinghong, Peng Zhang, Jing Tang, et al.. (2017). Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics. Nucleic Acids Research. 46(D1). D1121–D1127. 418 indexed citations breakdown →

19.

Zeng, Xian, Peng Zhang, Weidong He, et al.. (2017). NPASS: natural product activity and species source database for natural product research, discovery and tool development. Nucleic Acids Research. 46(D1). D1217–D1222. 162 indexed citations

20.

Zhong, Lei, et al.. (2014). A Preclinical Evaluation of SKLB261, a Multikinase Inhibitor of EGFR/Src/VEGFR2, as a Therapeutic Agent against Pancreatic Cancer. Molecular Cancer Therapeutics. 14(2). 407–418. 26 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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