Xuexiang Han

7.1k total citations · 10 hit papers
64 papers, 5.4k citations indexed

About

Xuexiang Han is a scholar working on Molecular Biology, Biomedical Engineering and Oncology. According to data from OpenAlex, Xuexiang Han has authored 64 papers receiving a total of 5.4k indexed citations (citations by other indexed papers that have themselves been cited), including 38 papers in Molecular Biology, 21 papers in Biomedical Engineering and 17 papers in Oncology. Recurrent topics in Xuexiang Han's work include RNA Interference and Gene Delivery (21 papers), Nanoplatforms for cancer theranostics (16 papers) and Advanced biosensing and bioanalysis techniques (14 papers). Xuexiang Han is often cited by papers focused on RNA Interference and Gene Delivery (21 papers), Nanoplatforms for cancer theranostics (16 papers) and Advanced biosensing and bioanalysis techniques (14 papers). Xuexiang Han collaborates with scholars based in China, United States and Australia. Xuexiang Han's co-authors include Guangjun Nie, Michael J. Mitchell, Yinlong Zhang, Yiye Li, Drew Weissman, Mohamad‐Gabriel Alameh, Xiao Zhao, Yingqiu Qi, Gregory J. Anderson and Ying Xu and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Xuexiang Han

63 papers receiving 5.3k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An ionizable lipid toolbox for RNA delivery

2021 415 citations Xuexiang Han, Kamila Butowska et al. Nature Communications profile →
Bioengineered bacteria-derived outer membrane vesicles as a versatile antigen display platform for tumor vaccination via Plug-and-Display technology

2021 359 citations Keman Cheng, Yao Li et al. Nature Communications profile →
Biomimetic Metal–Organic Framework Nanoparticles for Cooperative Combination of Antiangiogenesis and Photodynamic Therapy for Enhanced Efficacy

2019 356 citations Huan Min, Jing Wang et al. Advanced Materials profile →
Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines

2023 147 citations Xuexiang Han, Mohamad‐Gabriel Alameh et al. profile →
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment

2022 124 citations Lulu Xue, Ningqiang Gong et al. Journal of the American Chemical Society profile →
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis

2023 123 citations Xuexiang Han, Ningqiang Gong et al. Nature Communications profile →
In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism

2023 108 citations Margaret M. Billingsley, Ningqiang Gong et al. profile →
Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells

2022 90 citations Margaret M. Billingsley, Xuexiang Han et al. profile →
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models

2024 83 citations Lulu Xue, Alex G. Hamilton et al. Nature Communications profile →
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines

2023 68 citations Sarah J. Shepherd, Xuexiang Han et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Xuexiang Han China	42	2.6k	2.1k	1.2k	1.0k	840	64	5.4k
Ningqiang Gong China	41	2.4k 0.9×	2.4k 1.2×	1.0k 0.9×	1.6k 1.5×	805 1.0×	79	5.5k
Ronit Satchi‐Fainaro Israel	54	3.3k 1.3×	2.6k 1.3×	1.9k 1.6×	1.1k 1.1×	790 0.9×	158	7.5k
Xiao Zhao China	43	2.8k 1.1×	3.1k 1.5×	1.5k 1.2×	502 0.5×	1.7k 2.0×	89	6.4k
Keman Cheng China	31	1.7k 0.7×	2.2k 1.1×	860 0.7×	485 0.5×	1.2k 1.4×	52	4.3k
Sejin Son South Korea	31	1.8k 0.7×	2.4k 1.2×	1.3k 1.1×	702 0.7×	1.0k 1.2×	51	4.3k
Xiangrui Liu China	32	2.4k 0.9×	2.0k 0.9×	1.6k 1.3×	684 0.7×	522 0.6×	121	4.9k
Hai‐Yan Xie China	43	2.4k 0.9×	2.4k 1.2×	680 0.6×	1.9k 1.9×	599 0.7×	125	5.3k
Tuo Wei China	32	4.6k 1.8×	1.9k 0.9×	1.8k 1.5×	758 0.7×	683 0.8×	68	7.1k
Luis J. Cruz Netherlands	47	2.6k 1.0×	1.9k 0.9×	1.3k 1.1×	719 0.7×	2.5k 3.0×	153	6.4k
Song Shen China	39	2.2k 0.8×	2.4k 1.2×	1.6k 1.3×	556 0.5×	1.2k 1.4×	82	5.0k

Countries citing papers authored by Xuexiang Han

Since Specialization

Citations

This map shows the geographic impact of Xuexiang Han's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xuexiang Han with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xuexiang Han more than expected).

Fields of papers citing papers by Xuexiang Han

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xuexiang Han. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xuexiang Han. The network helps show where Xuexiang Han may publish in the future.

Co-authorship network of co-authors of Xuexiang Han

This figure shows the co-authorship network connecting the top 25 collaborators of Xuexiang Han. A scholar is included among the top collaborators of Xuexiang Han based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xuexiang Han. Xuexiang Han is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Xue, Lulu, Xinhong Xiong, Gan Zhao, et al.. (2025). Multiarm-Assisted Design of Dendron-like Degradable Ionizable Lipids Facilitates Systemic mRNA Delivery to the Spleen. Journal of the American Chemical Society. 147(2). 1542–1552. 10 indexed citations

Gong, Ningqiang, Dongyoon Kim, Mohamad‐Gabriel Alameh, et al.. (2025). Mannich reaction-based combinatorial libraries identify antioxidant ionizable lipids for mRNA delivery with reduced immunogenicity. Nature Biomedical Engineering. 9(12). 2181–2195. 2 indexed citations

Hamilton, Alex G., Kelsey L. Swingle, Ajay S. Thatte, et al.. (2024). High-Throughput In Vivo Screening Identifies Differential Influences on mRNA Lipid Nanoparticle Immune Cell Delivery by Administration Route. ACS Nano. 18(25). 16151–16165. 25 indexed citations

Gong, Ningqiang, Xuexiang Han, Lulu Xue, et al.. (2024). Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature Biomedical Engineering. 8(5). 513–528. 14 indexed citations

Xue, Lulu, Alex G. Hamilton, Gan Zhao, et al.. (2024). High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature Communications. 15(1). 1884–1884. 83 indexed citations breakdown →

Han, Xuexiang, Mohamad‐Gabriel Alameh, Ningqiang Gong, et al.. (2024). Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo. Nature Chemistry. 16(10). 1687–1697. 44 indexed citations

Han, Xuexiang, Mohamad‐Gabriel Alameh, Ying Xu, et al.. (2024). Optimization of the activity and biodegradability of ionizable lipids for mRNA delivery via directed chemical evolution. Nature Biomedical Engineering. 8(11). 1412–1424. 22 indexed citations

Han, Xuexiang, Junchao Xu, Ying Xu, et al.. (2024). In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors. Nature Communications. 15(1). 1762–1762. 41 indexed citations

Gong, Ningqiang, Wenqun Zhong, Mohamad‐Gabriel Alameh, et al.. (2024). Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery. Nature Materials. 23(12). 1736–1747. 31 indexed citations

10.

Swingle, Kelsey L., Alex G. Hamilton, Hannah C. Safford, et al.. (2024). Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia. Nature. 637(8045). 412–421. 39 indexed citations

11.

Mukalel, Alvin J., Alex G. Hamilton, Margaret M. Billingsley, et al.. (2024). Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering. Advanced Functional Materials. 34(27). 26 indexed citations

12.

Gong, Ningqiang, Xuexiang Han, Lulu Xue, et al.. (2023). In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity. Nature Materials. 22(12). 1571–1580. 49 indexed citations

13.

Shepherd, Sarah J., Xuexiang Han, Alvin J. Mukalel, et al.. (2023). Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines. Proceedings of the National Academy of Sciences. 120(33). e2303567120–e2303567120. 68 indexed citations breakdown →

14.

Han, Xuexiang, Ningqiang Gong, Lulu Xue, et al.. (2023). Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis. Nature Communications. 14(1). 75–75. 123 indexed citations breakdown →

15.

Butowska, Kamila, Xuexiang Han, Ningqiang Gong, et al.. (2022). Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy. Acta Pharmaceutica Sinica B. 13(4). 1429–1437. 49 indexed citations

16.

Han, Xuexiang, et al.. (2019). Emerging nanomedicines for anti-stromal therapy against desmoplastic tumors. Biomaterials. 232. 119745–119745. 62 indexed citations

17.

Min, Huan, Jing Wang, Yingqiu Qi, et al.. (2019). Biomimetic Metal–Organic Framework Nanoparticles for Cooperative Combination of Antiangiogenesis and Photodynamic Therapy for Enhanced Efficacy. Advanced Materials. 31(15). e1808200–e1808200. 356 indexed citations breakdown →

18.

Han, Xuexiang & Guangjun Nie. (2019). Say No to Tumors: NO Matters. Matter. 1(4). 794–796. 5 indexed citations

19.

Wang, Bin, Yanping Ding, Xiaozheng Zhao, et al.. (2018). Delivery of small interfering RNA against Nogo-B receptor via tumor-acidity responsive nanoparticles for tumor vessel normalization and metastasis suppression. Biomaterials. 175. 110–122. 55 indexed citations

20.

Li, Feng, Yiye Li, Xiao Yang, et al.. (2018). Highly Fluorescent Chiral N‐S‐Doped Carbon Dots from Cysteine: Affecting Cellular Energy Metabolism. Angewandte Chemie International Edition. 57(9). 2377–2382. 305 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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