Xizhen Lian

4.6k total citations · 6 hit papers
25 papers, 3.7k citations indexed

About

Xizhen Lian is a scholar working on Inorganic Chemistry, Materials Chemistry and Molecular Biology. According to data from OpenAlex, Xizhen Lian has authored 25 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Inorganic Chemistry, 13 papers in Materials Chemistry and 10 papers in Molecular Biology. Recurrent topics in Xizhen Lian's work include Metal-Organic Frameworks: Synthesis and Applications (14 papers), RNA Interference and Gene Delivery (8 papers) and Advanced biosensing and bioanalysis techniques (6 papers). Xizhen Lian is often cited by papers focused on Metal-Organic Frameworks: Synthesis and Applications (14 papers), RNA Interference and Gene Delivery (8 papers) and Advanced biosensing and bioanalysis techniques (6 papers). Xizhen Lian collaborates with scholars based in United States, China and South Korea. Xizhen Lian's co-authors include Hong‐Cai Zhou, Yu Fang, Xuan Wang, Jialuo Li, Elizabeth Joseph, Sayan Banerjee, Christina Lollar, Qi Wang, Tian‐Fu Liu and Ying‐Pin Chen and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Chemical Society Reviews.

In The Last Decade

Xizhen Lian

24 papers receiving 3.7k citations

Hit Papers

Enzyme–MOF (metal–organic framework) composites 2015 2026 2018 2022 2017 2015 2022 2023 2023 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Enzyme–MOF (metal–organic framework) composites
    2017 1.2k citations Xizhen Lian, Yu Fang et al. Chemical Society Reviews profile →
  2. Stable metal-organic frameworks containing single-molecule traps for enzyme encapsulation
    2015 590 citations Dawei Feng, Tian‐Fu Liu et al. Nature Communications profile →
  3. Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery
    2022 328 citations Xu Wang, Shuai Liu et al. profile →
  4. Lung SORT LNPs enable precise homology-directed repair mediated CRISPR/Cas genome correction in cystic fibrosis models
    2023 103 citations Tuo Wei, Yehui Sun et al. Nature Communications profile →
  5. The interplay of quaternary ammonium lipid structure and protein corona on lung-specific mRNA delivery by selective organ targeting (SORT) nanoparticles
    2023 85 citations Sean A. Dilliard, Yehui Sun et al. Journal of Controlled Release profile →
  6. High-density brush-shaped polymer lipids reduce anti-PEG antibody binding for repeated administration of mRNA therapeutics
    2025 21 citations Yufen Xiao, Xizhen Lian et al. Nature Materials profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Xizhen Lian United States 19 2.0k 1.9k 1.2k 671 658 25 3.7k
Weibin Liang Australia 31 2.4k 1.2× 2.3k 1.2× 694 0.6× 687 1.0× 654 1.0× 65 4.0k
Ulrich Lächelt Germany 31 1.5k 0.8× 1.5k 0.8× 2.1k 1.7× 1.0k 1.5× 329 0.5× 76 4.6k
Ming‐Xue Wu China 22 2.1k 1.1× 1.9k 1.0× 389 0.3× 1.1k 1.7× 538 0.8× 39 3.7k
Xiaoyu Xu China 31 1.7k 0.8× 1.5k 0.8× 677 0.6× 738 1.1× 483 0.7× 78 3.4k
Zhan Zhou China 39 2.8k 1.4× 924 0.5× 657 0.5× 1.4k 2.1× 857 1.3× 110 4.4k
Tamim Chalati France 5 2.4k 1.2× 3.2k 1.7× 622 0.5× 1.3k 2.0× 494 0.8× 6 4.7k
Lien‐Yang Chou United States 31 3.0k 1.5× 2.6k 1.3× 878 0.7× 848 1.3× 1.8k 2.7× 57 5.7k
Michael W. Ambrogio United States 18 2.1k 1.1× 1.2k 0.6× 443 0.4× 659 1.0× 236 0.4× 26 3.3k
Wen Cai China 26 1.5k 0.7× 893 0.5× 411 0.3× 1.0k 1.5× 684 1.0× 61 2.9k

Countries citing papers authored by Xizhen Lian

Since Specialization
Citations

This map shows the geographic impact of Xizhen Lian's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xizhen Lian with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xizhen Lian more than expected).

Fields of papers citing papers by Xizhen Lian

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xizhen Lian. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xizhen Lian. The network helps show where Xizhen Lian may publish in the future.

Co-authorship network of co-authors of Xizhen Lian

This figure shows the co-authorship network connecting the top 25 collaborators of Xizhen Lian. A scholar is included among the top collaborators of Xizhen Lian based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xizhen Lian. Xizhen Lian is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Xiao, Yufen, Xizhen Lian, Yehui Sun, et al.. (2025). High-density brush-shaped polymer lipids reduce anti-PEG antibody binding for repeated administration of mRNA therapeutics. Nature Materials. 24(11). 1840–1851. 21 indexed citations breakdown →
2.
Robinson, Joshua, Di Zhang, Pratima Basak, et al.. (2025). Reducing Complexity in Lipid Nanoparticles: Three-Component Zwitterionic Amino Lipids for Targeted Extrahepatic mRNA Delivery. ACS Biomaterials Science & Engineering. 11(8). 4853–4868.
3.
Park, Chan Ho, Ian A. P. Thompson, Sharon Newman, et al.. (2024). Real‐Time Spatiotemporal Measurement of Extracellular Signaling Molecules Using an Aptamer Switch‐Conjugated Hydrogel Matrix (Adv. Mater. 4/2024). Advanced Materials. 36(4). 1 indexed citations
4.
Dilliard, Sean A., Yehui Sun, Yun‐Chieh Sung, et al.. (2023). The interplay of quaternary ammonium lipid structure and protein corona on lung-specific mRNA delivery by selective organ targeting (SORT) nanoparticles. Journal of Controlled Release. 361. 361–372. 85 indexed citations breakdown →
5.
Cheng, Qiang, Lukas Farbiak, Amogh Vaidya, et al.. (2023). In situ production and secretion of proteins endow therapeutic benefit against psoriasiform dermatitis and melanoma. Proceedings of the National Academy of Sciences. 120(52). e2313009120–e2313009120. 11 indexed citations
6.
Park, Chan Ho, Ian A. P. Thompson, Sharon Newman, et al.. (2023). Real‐Time Spatiotemporal Measurement of Extracellular Signaling Molecules Using an Aptamer Switch‐Conjugated Hydrogel Matrix. Advanced Materials. 36(4). e2306704–e2306704. 12 indexed citations
7.
Wei, Tuo, Yehui Sun, Qiang Cheng, et al.. (2023). Lung SORT LNPs enable precise homology-directed repair mediated CRISPR/Cas genome correction in cystic fibrosis models. Nature Communications. 14(1). 7322–7322. 103 indexed citations breakdown →
8.
Lian, Xizhen, Yanyan Huang, Yuan‐Yuan Zhu, et al.. (2018). Enzyme‐MOF Nanoreactor Activates Nontoxic Paracetamol for Cancer Therapy. Angewandte Chemie International Edition. 57(20). 5725–5730. 247 indexed citations
9.
Lian, Xizhen, Yanyan Huang, Yuan‐Yuan Zhu, et al.. (2018). Enzyme‐MOF Nanoreactor Activates Nontoxic Paracetamol for Cancer Therapy. Angewandte Chemie. 130(20). 5827–5832. 48 indexed citations
10.
Fang, Yu, Jialuo Li, Zhifeng Xiao, et al.. (2018). Ultra-Small Face-Centered-Cubic Ru Nanoparticles Confined within a Porous Coordination Cage for Dehydrogenation. Chem. 4(3). 555–563. 134 indexed citations
11.
12.
Fang, Yu, Zhifeng Xiao, Jialuo Li, et al.. (2018). Formation of a Highly Reactive Cobalt Nanocluster Crystal within a Highly Negatively Charged Porous Coordination Cage. Angewandte Chemie International Edition. 57(19). 5283–5287. 96 indexed citations
13.
Wang, Qi, Xizhen Lian, Yu Fang, & Hong‐Cai Zhou. (2018). Applications of Immobilized Bio-Catalyst in Metal-Organic Frameworks. Catalysts. 8(4). 166–166. 25 indexed citations
14.
Lian, Xizhen, Alfredo Erazo‐Oliveras, Jean‐Philippe Pellois, & Hong‐Cai Zhou. (2017). High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks. Nature Communications. 8(1). 2075–2075. 146 indexed citations
15.
Lian, Xizhen, Yu Fang, Elizabeth Joseph, et al.. (2017). Enzyme–MOF (metal–organic framework) composites. Chemical Society Reviews. 46(11). 3386–3401. 1178 indexed citations breakdown →
16.
Qin, Jun‐Sheng, Dong‐Ying Du, Mian Li, et al.. (2016). Derivation and Decoration of Nets with Trigonal-Prismatic Nodes: A Unique Route to Reticular Synthesis of Metal–Organic Frameworks. Journal of the American Chemical Society. 138(16). 5299–5307. 86 indexed citations
17.
Yuan, Shuai, Ying‐Pin Chen, Jun‐Sheng Qin, et al.. (2015). Cooperative Cluster Metalation and Ligand Migration in Zirconium Metal–Organic Frameworks. Angewandte Chemie. 127(49). 14909–14913. 26 indexed citations
18.
Lian, Xizhen, Dawei Feng, Ying‐Pin Chen, et al.. (2015). The preparation of an ultrastable mesoporous Cr(iii)-MOF via reductive labilization. Chemical Science. 6(12). 7044–7048. 68 indexed citations
19.
Feng, Dawei, Tian‐Fu Liu, Jie Su, et al.. (2015). Stable metal-organic frameworks containing single-molecule traps for enzyme encapsulation. Nature Communications. 6(1). 5979–5979. 590 indexed citations breakdown →
20.
Yuan, Shuai, Jun‐Sheng Qin, Weigang Lu, et al.. (2015). Cooperative Cluster Metalation and Ligand Migration in Zirconium Metal–Organic Frameworks. Angewandte Chemie International Edition. 54(49). 14696–14700. 164 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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