Xian Chen

15.8k total citations
127 papers, 4.7k citations indexed

About

Xian Chen is a scholar working on Molecular Biology, Spectroscopy and Oncology. According to data from OpenAlex, Xian Chen has authored 127 papers receiving a total of 4.7k indexed citations (citations by other indexed papers that have themselves been cited), including 94 papers in Molecular Biology, 39 papers in Spectroscopy and 18 papers in Oncology. Recurrent topics in Xian Chen's work include Ubiquitin and proteasome pathways (34 papers), Advanced Proteomics Techniques and Applications (30 papers) and Protein Degradation and Inhibitors (27 papers). Xian Chen is often cited by papers focused on Ubiquitin and proteasome pathways (34 papers), Advanced Proteomics Techniques and Applications (30 papers) and Protein Degradation and Inhibitors (27 papers). Xian Chen collaborates with scholars based in United States, China and Netherlands. Xian Chen's co-authors include Yanbao Yu, Jian Jin, E. Morton Bradbury, Sheng Gu, Ling Xie, Songqin Pan, Jing Liu, Haining Zhu, H. Ümit Kanıskan and Harsha P. Gunawardena and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Xian Chen

121 papers receiving 4.7k citations

Peers

Countries citing papers authored by Xian Chen

Since Specialization

Citations

This map shows the geographic impact of Xian Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xian Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xian Chen more than expected).

Fields of papers citing papers by Xian Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xian Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xian Chen. The network helps show where Xian Chen may publish in the future.

Co-authorship network of co-authors of Xian Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Xian Chen. A scholar is included among the top collaborators of Xian Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xian Chen. Xian Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Heat shock protein 90 chaperone activity is required for hepatitis A virus replication 2025 ·Journal of Virology ·You Li, (unknown), Ling Xie, Maryna Kapustina, Takayoshi Shirasaki, Bryan Yonish, Xian Chen, Asuka Hirai-Yuki, Noriyo Nagata, Ryosuke Suzuki, Masanori Isogawa, Matthew R. Vogt, Masamichi Muramatsu, Stanley M. Lemon	1
2	Discovery of the first-in-class DOT1L PROTAC degrader 2025 ·European Journal of Medicinal Chemistry ·(unknown), Renhong Sun, Zhongli Xu, Huen Suk Kim, Min Jeong Kim, Tao Cao, Ling Xie, Xian Chen, H. Ümit Kanıskan, Jian Jin	2
3	A potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression 2024 ·Science Advances ·Zhaoyu Xue, (unknown), (unknown), (unknown), Mengying Huang, Ling Xie, Yangzhou Su, Longxia Xu, (unknown), Brandon Dale, Xiaobing Shi, Xian Chen, H. Ümit Kanıskan, Jian Jin, Hong Wen	1
4	Telomere Targeting Chimera Enables Targeted Destruction of Telomeric Repeat-Binding Factor Proteins 2023 ·Journal of the American Chemical Society ·Zhen Wang, Jing Liu, He Chen, Xing Qiu, Ling Xie, H. Ümit Kanıskan, Xian Chen, Jian Jin, Wenyi Wei	19
5	Methylated Nucleotide-Based Proteolysis-Targeting Chimera Enables Targeted Degradation of Methyl-CpG-Binding Protein 2 2023 ·Journal of the American Chemical Society ·Zhen Wang, Jing Liu, Xing Qiu, Dingpeng Zhang, Hiroyuki Inuzuka, Li Chen, He Chen, Ling Xie, H. Ümit Kanıskan, Xian Chen, Jian Jin, Wenyi Wei	9
6	Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation 2023 ·Cell chemical biology ·(unknown), Li Wang, Ling Xie, Feng Zhang, (unknown), Mei Liu, Erik M. Lenarcic, (unknown), Juan Song, Yan Xiong, Xufen Yu, Charles Wang, Kanishk Jain, Brian D. Strahl, Jeanette Gowen Cook, Yisong Y. Wan, Nathaniel J. Moorman, Hongjun Song, Jian Jin, Xian Chen	6
7	Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX 2022 ·PLoS Pathogens ·Takayoshi Shirasaki, Hui Feng, Helen M. E. Duyvesteyn, William G. Fusco, Kevin L. McKnight, Ling Xie, Mark Boyce, (unknown), Rina Barouch‐Bentov, Olga González‐López, Ryan P. McNamara, Li Wang, (unknown), Xian Chen, Shirit Einav, Joseph A. Duncan, Maryna Kapustina, Elizabeth E. Fry, David I. Stuart, Stanley M. Lemon	10
8	TF-DUBTACs Stabilize Tumor Suppressor Transcription Factors 2022 ·Journal of the American Chemical Society ·Jing Liu, Xufen Yu, He Chen, H. Ümit Kanıskan, Ling Xie, Xian Chen, Jian Jin, Wenyi Wei	42
9	Discovery of the First Lactate Dehydrogenase Proteolysis Targeting Chimera Degrader for the Treatment of Pancreatic Cancer 2022 ·Journal of Medicinal Chemistry ·Ning Sun, Md Kabir, (unknown), Ling Xie, Xiao Hu, (unknown), Xian Chen, H. Ümit Kanıskan, Jian Jin	22
10	Targeting Triple-Negative Breast Cancer by a Novel Proteolysis Targeting Chimera Degrader of Enhancer of Zeste Homolog 2 2022 ·ACS Pharmacology & Translational Science ·Brandon Dale, (unknown), Kwang‐Su Park, H. Ümit Kanıskan, Anqi Ma, Yudao Shen, Chengwei Zhang, Ling Xie, Xian Chen, Xufen Yu, Jian Jin	32
11	Nonlytic Quasi-Enveloped Hepatovirus Release Is Facilitated by pX Protein Interaction with the E3 Ubiquitin Ligase ITCH 2022 ·Journal of Virology ·Takayoshi Shirasaki, Olga González‐López, Kevin L. McKnight, Ling Xie, Tomoyuki Shiota, Xian Chen, Hui Feng, Stanley M. Lemon	7
12	Harnessing the E3 Ligase KEAP1 for Targeted Protein Degradation 2021 ·Journal of the American Chemical Society ·(unknown), Fanye Meng, Kwang‐Su Park, (unknown), (unknown), (unknown), Li Wang, Ling Xie, He Chen, Yudao Shen, (unknown), Dongxu Li, Gang Greg Wang, Xian Chen, H. Ümit Kanıskan, Jian Jin	96
13	TF-PROTACs Enable Targeted Degradation of Transcription Factors 2021 ·Journal of the American Chemical Society ·Jing Liu, He Chen, H. Ümit Kanıskan, Ling Xie, Xian Chen, Jian Jin, Wenyi Wei	178
14	AIM2 in regulatory T cells restrains autoimmune diseases 2021 ·Nature ·Wei-Chun Chou, Zengli Guo, Hao Guo, Liang Chen, Ge Zhang, Kaixin Liang, Ling Xie, Xianming Tan, Sara A. Gibson, Elena Rampanelli, Yan Wang, Stephanie A. Montgomery, W. June Brickey, Meng Deng, Leslie Freeman, Song Zhang, Maureen A. Su, Xian Chen, Yisong Y. Wan, Jenny P.‐Y. Ting	125
15	Distinct CDK6 complexes determine tumor cell response to CDK4/6 inhibitors and degraders 2021 ·Nature Cancer ·Xuewei Wu, Xiaobao Yang, Yan Xiong, Ruitong Li, Takahiro Ito, Tamer A. Ahmed, Zoi Karoulia, Christos Adamopoulos, Hong Wang, Li Wang, Ling Xie, Jing Liu, Beatrix Ueberheide, Stuart A. Aaronson, Xian Chen, Sean G. Buchanan, William R. Sellers, Jian Jin, Poulikos I. Poulikakos	47
16	CRL4 ^DCAF1/VprBP E3 ubiquitin ligase controls ribosome biogenesis, cell proliferation, and development 2020 ·Science Advances ·Xiaoran Han, Naoya Sasaki, Sarah Jackson, Pu Wang, Zhijun Li, Matthew D. Smith, Ling Xie, Xian Chen, Yanping Zhang, William F. Marzluff, Yue Xiong	31
17	Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) Degraders 2020 ·Journal of Medicinal Chemistry ·Yudao Shen, Guozhen Gao, Xufen Yu, (unknown), (unknown), Ling Xie, Megan Schwarz, Xian Chen, Ernesto Guccione, Jing Liu, Mark T. Bedford, Jian Jin	69
18	TBK1 Is a Synthetic Lethal Target in Cancer with VHL Loss 2019 ·Cancer Discovery ·Lianxin Hu, Haibiao Xie, Xijuan Liu, Frances Potjewyd, Lindsey I. James, Emily Wilkerson, Laura E. Herring, Ling Xie, Xian Chen, (unknown), Kai Hong, Chengheng Liao, Xianming Tan, Albert S. Baldwin, Kan Gong, Qing Zhang	72
19	Cyclin E Overexpression Sensitizes Triple-Negative Breast Cancer to Wee1 Kinase Inhibition 2018 ·Clinical Cancer Research ·Xian Chen, (unknown), Angela Alexander, Yufeng Jiang, Cansu Karakaş, Kenneth R. Hess, Jason P.W. Carey, Tuyen Bui, Smruthi Vijayaraghavan, Kurt W. Evans, Min Yi, (unknown), Kwok‐Leung Cheung, Ian O. Ellis, Siqing Fu, Funda Meric‐Bernstam, Kelly K. Hunt, Khandan Keyomarsi	78
20	Sequential Combination Therapy of CDK Inhibition and Doxorubicin Is Synthetically Lethal in p53-Mutant Triple-Negative Breast Cancer 2016 ·Molecular Cancer Therapeutics ·(unknown), Xian Chen, Tuyen Bui, Yufeng Jiang, Dong Yang, Smruthi Vijayaraghavan, Mark J. McArthur, Kelly K. Hunt, Khandan Keyomarsi	51

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact