Xavier de Leval

1.6k citations

46 papers · 1.4k indexed · h-index 25

Impact in

Pharmacology top 2%
- Inflammatory mediators and NSAID effects
Biochemistry top 5%
- Eicosanoids and Hypertension Pharmacology

Papers in

Pharmacology 35
- Inflammatory mediators and NSAID effects 35
Biochemistry 7
- Eicosanoids and Hypertension Pharmacology 7

Co-authors: Bernard Pirotte Jean‐Michel Dogné Fabien Julémont J. Delarge Bernard Masereel Jean‐Louis David Julien Hanson Vincent Castronovo
Journals: Current Medicinal Chemistry (7 papers)Expert Opinion on Therapeutic Patents (6 papers)Journal of Medicinal Chemistry (5 papers)Mini-Reviews in Medicinal Chemistry (4 papers)Prostaglandins Leukotrienes and Essential Fatty Acids (4 papers)
Partner nations: Belgium New Zealand Italy

In The Last Decade

Xavier de Leval

46 papers receiving 1.3k citations

Peers

Countries citing papers authored by Xavier de Leval

Since Specialization

Citations

This map shows the geographic impact of Xavier de Leval's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xavier de Leval with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xavier de Leval more than expected).

Fields of papers citing papers by Xavier de Leval

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xavier de Leval. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xavier de Leval. The network helps show where Xavier de Leval may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Xavier de Leval, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Xavier de Leval Line = papers co-authored together Xavier de Leval links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	N-(3-Arylaminopyridin-4-yl)alkanesulfonamides as pyridine analogs of nimesulide: Cyclooxygenases inhibition, anti-inflammatory studies and insight on metabolism European Journal of Medicinal Chemistry ·Jaswantsingh Shekhawat, Frédéric Lecomte, Philippe Hubert, Xavier de Leval, Bernard Pirotte	2014	31
2	Evaluation of Original Dual Thromboxane A2 Modulators as Antiangiogenic Agents Journal of Pharmacology and Experimental Therapeutics ·Xavier de Leval, Keith Haynes, Jean‐Michel Dogné, David Waltregny, Akeila Bellahcène, Valérie Benoît, Bernard Pirotte, Vincent Castronovo	2006	14
3	From the Design to the Clinical Application of Thromboxane Modulators Current Pharmaceutical Design ·Jean‐Michel Dogné, Julien Hanson, Xavier de Leval, Domenico Praticò, C.R. Pace-Asciak, Pierre Drion, Bernard Pirotte, Ke‐He Ruan	2006	45
4	Activation of the Thromboxane A2 Pathway in Human Prostate Cancer Correlates with Tumor Gleason Score and Pathologic Stage European Urology ·Keith Haynes, Xavier de Leval, Laurence de Leval, Bernard Pirotte, Vincent Castronovo, David Waltregny	2006	39
5	A new potential cyclooxygenase-2 inhibitor, pyridinic analogue of nimesulide European Journal of Medicinal Chemistry ·Catherine Michaux, Caroline Charlier, Fabien Julémont, Xavier de Leval, Jean‐Michel Dogné, Bernard Pirotte, F. Durant	2005	24
6	Synthesis, molecular modelling and enzymatic evaluation of (±)3,5-diphenyl-2-thioxoimidazolidin-4-ones as new potential cyclooxygenase inhibitors Bioorganic & Medicinal Chemistry ·П А Слепнев, Catherine Michaux, Stéphanie Rolin, Giovana Biasia De [UNIFESP] Sousa, Xavier de Leval, Fabien Julémont, Lionel Pochet, Bernard Masereel	2005	16
7	Regulation of HER-2 oncogene expression by cyclooxygenase-2 and prostaglandin E2 Oncogene ·Valérie Benoît, Biserka Relić, Xavier de Leval, Alain Chariot, Marie‐Paule Merville, Vincent Bours	2004	62
8	New Developments on Thromboxane and Prostacyclin Modulators Part I: Thromboxane Modulators Current Medicinal Chemistry ·Jean‐Michel Dogné, Xavier de Leval, Julien Hanson, Michel Frédérich, Bernard Lambermont, Alexandre Ghuysen, Angela Casini, Bernard Masereel, Ke‐He Ruan, Bernard Pirotte, Philippe Kolh	2004	68
9	New Developments on Thromboxane Modulators Mini-Reviews in Medicinal Chemistry ·Jean‐Michel Dogné, Julien Hanson, Xavier de Leval, Bernard Masereel, Philippe Kolh, Bernard Pirotte	2004	11
10	Modulation of the Arachidonic Cascade with ω3 Fatty Acids or Analogues: Potential Therapeutic Benefits Mini-Reviews in Medicinal Chemistry ·Isabelle Roland, Xavier de Leval, Brigitte Évrard, Bernard Pirotte, Jean-Michel Dogné, Luc Delattre	2004	9
11	Pharmacological Characterization of N-tert-Butyl-N′-[2-(4′-methylphenylamino)-5-nitrobenzenesulfonyl]urea (BM-573), a Novel Thromboxane A2 Receptor Antagonist and Thromboxane Synthase Inhibitor in a Rat Model of Arterial Thrombosis and Its Effects on Bleeding Time Journal of Pharmacology and Experimental Therapeutics ·Jean‐Michel Dogné, Julien Hanson, Xavier de Leval, Philippe Kolh, Vincent Tchana‐Sato, Laurence de Leval, Stéphanie Rolin, Alexandre Ghuysen, Patrick Segers, Bernard Lambermont, Bernard Masereel, Bernard Pirotte	2004	24
12	Effects of COX-2 inhibitors on ROS produced by Chlamydia pneumoniae-primed human promonocytic cells (THP-1) Biochemical and Biophysical Research Communications ·Ange Mouithys‐Mickalad, G. Deby‐Dupont, Jean‐Michel Dogné, Xavier de Leval, Stéphan Kohnen, Rachel Navet, Francis Sluse, Maryse Hoebeke, Bernard Pirotte, Maurice Lamy	2004	19
13	Recent Development in the Field of Dual COX / 5-LOX Inhibitors Mini-Reviews in Medicinal Chemistry ·Fabien Julémont, Jean‐Michel Dogné, Bernard Pirotte, Xavier de Leval	2004	31
14	Pharmacological evaluation of the novel thromboxane modulator BM-567 (II/II). Effects of BM-567 on osteogenic sarcoma-cell-induced platelet aggregation Prostaglandins Leukotrienes and Essential Fatty Acids ·Xavier de Leval, Valérie Benoît, J. Delarge, Fabien Julémont, Bernard Masereel, Bernard Pirotte, Sandra Milena Parra García, Jean‐Louis David, Jean‐Michel Dogné	2003	36
15	N-(3-Phenoxy-4-pyridinio)methanesulfonamidate Acta Crystallographica Section C Crystal Structure Communications ·Catherine Michaux, Caroline Charlier, Fabien Julémont, Jean‐Michel Dogné, Xavier de Leval, Bernadette Norberg, Bernard Pirotte, F. Durant	2002	3
16	Recent Advances in Antiplatelet Agents Current Medicinal Chemistry ·Jean‐Michel Dogné, Xavier de Leval, P Benoît, J. Delarge, Bernard Masereel, Jean‐Louis David	2002	45
17	Thromboxane A2 Inhibition Jean‐Michel Dogné, Xavier de Leval, P Benoît, J. Delarge, Bernard Masereel	2002	27
18	Evaluation of classical NSAIDs and COX-2 selective inhibitors on purified ovine enzymes and human whole blood Prostaglandins Leukotrienes and Essential Fatty Acids ·Xavier de Leval, J. Delarge, 理広西, P. Neven, Catherine Michaux, Bernard Masereel, Bernard Pirotte, Jean‐Louis David, Yves Henrotin, Jean‐Michel Dogné	2001	23
19	In vitro effects of aceclofenac and its metabolites on the production by chondrocytes of inflammatory mediators Inflammation Research ·Yves Henrotin, Xavier de Leval, F. Sáez, Ange Mouithys‐Mickalad, G. Deby‐Dupont, Jean‐Michel Dogné, J. Delarge, Jean‐Yves Reginster	2001	31
20	New Trends in Thromboxane and Prostacyclin Modulators Current Medicinal Chemistry ·E Reséndiz-Meléndez, Xavier de Leval, J. Delarge, Erliza Mea Famisaran, Bernard Masereel	2000	30

About Xavier de Leval

Xavier de Leval is a scholar working on Pharmacology, Biochemistry, Organic Chemistry, Genetics and Cardiology and Cardiovascular Medicine, having authored 46 papers that have together received 1.4k indexed citations. Recurring topics across this work include Inflammatory mediators and NSAID effects (35 papers), Estrogen and related hormone effects (15 papers), Synthesis and biological activity (10 papers), Antiplatelet Therapy and Cardiovascular Diseases (8 papers), Eicosanoids and Hypertension Pharmacology (7 papers), Synthesis and Reactions of Organic Compounds (4 papers), Enzyme function and inhibition (3 papers) and Synthesis and Catalytic Reactions (3 papers). The work is most often cited by research in Pharmacology (557 citations), Biochemistry (160 citations), Organic Chemistry (422 citations), Toxicology (38 citations) and Pharmacology (94 citations). Xavier de Leval has collaborated with scholars based in Belgium, New Zealand and Italy. Frequent co-authors include Bernard Pirotte, Jean‐Michel Dogné, Fabien Julémont, J. Delarge, Bernard Masereel, Jean‐Louis David, Julien Hanson, J. Delarge, Vincent Castronovo and David Waltregny. Their work appears in journals such as Current Medicinal Chemistry, Expert Opinion on Therapeutic Patents, Journal of Medicinal Chemistry, Mini-Reviews in Medicinal Chemistry and Prostaglandins Leukotrienes and Essential Fatty Acids.

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