Xavier Darzacq

20.7k total citations · 9 hit papers
112 papers, 13.1k citations indexed

About

Xavier Darzacq is a scholar working on Molecular Biology, Biophysics and Cell Biology. According to data from OpenAlex, Xavier Darzacq has authored 112 papers receiving a total of 13.1k indexed citations (citations by other indexed papers that have themselves been cited), including 94 papers in Molecular Biology, 28 papers in Biophysics and 10 papers in Cell Biology. Recurrent topics in Xavier Darzacq's work include RNA Research and Splicing (56 papers), Genomics and Chromatin Dynamics (48 papers) and Advanced Fluorescence Microscopy Techniques (26 papers). Xavier Darzacq is often cited by papers focused on RNA Research and Splicing (56 papers), Genomics and Chromatin Dynamics (48 papers) and Advanced Fluorescence Microscopy Techniques (26 papers). Xavier Darzacq collaborates with scholars based in United States, France and Israel. Xavier Darzacq's co-authors include Robert Tjian, Anders S. Hansen, Mustafa Mir, Claudia Cattoglio, Robert H. Singer, Yaron Shav‐Tal, Claire Dugast‐Darzacq, Dmitry V. Fyodorov, Alexander Emelyanov and Gary H. Karpen and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Xavier Darzacq

110 papers receiving 13.0k citations

Hit Papers

Phase separation drives heterochromatin ... 2007 2026 2013 2019 2017 2018 2007 2019 2018 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Phase separation drives heterochromatin domain formation
    2017 1.3k citations Mustafa Mir, Xavier Darzacq et al. profile →
  2. Imaging dynamic and selective low-complexity domain interactions that control gene transcription
    2018 673 citations Shasha Chong, Claire Dugast‐Darzacq et al. Science profile →
  3. In vivo dynamics of RNA polymerase II transcription
    2007 513 citations Xavier Darzacq et al. Nature Structural & Molecular Biology profile →
  4. Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences
    2019 420 citations Mustafa Mir, Xavier Darzacq et al. Genes & Development profile →
  5. Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II
    2018 416 citations Alec Heckert, Xavier Darzacq et al. profile →
  6. CTCF and cohesin regulate chromatin loop stability with distinct dynamics
    2017 414 citations Claudia Cattoglio, Robert Tjian et al. eLife profile →
  7. RNA polymerase II clustering through carboxy-terminal domain phase separation
    2018 408 citations Claire Dugast‐Darzacq, Gina M. Dailey et al. Nature Structural & Molecular Biology profile →
  8. Resolving the 3D Landscape of Transcription-Linked Mammalian Chromatin Folding
    2020 365 citations Tsung-Han S. Hsieh, Claudia Cattoglio et al. Molecular Cell profile →
  9. Enhancer–promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1
    2022 208 citations Tsung-Han S. Hsieh, Claudia Cattoglio et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Xavier Darzacq United States 53 11.3k 1.5k 1.2k 834 702 112 13.1k
M. Cristina Cardoso Germany 55 9.9k 0.9× 1.0k 0.7× 652 0.5× 1.7k 2.0× 1.0k 1.5× 186 12.1k
Ghia Euskirchen United States 27 7.4k 0.7× 1.6k 1.0× 1.1k 0.9× 1.8k 2.1× 685 1.0× 33 10.0k
James G. McNally United States 55 7.6k 0.7× 1.8k 1.2× 726 0.6× 1.0k 1.2× 1.7k 2.4× 134 10.3k
Peter R. Cook United Kingdom 65 13.0k 1.1× 541 0.4× 1.7k 1.4× 1.9k 2.3× 1.0k 1.4× 210 14.9k
Lothar Schermelleh Germany 48 6.4k 0.6× 2.6k 1.7× 802 0.7× 1.1k 1.3× 1.3k 1.8× 78 9.4k
Karsten Rippe Germany 56 9.7k 0.9× 585 0.4× 1.5k 1.2× 1.2k 1.4× 441 0.6× 167 11.3k
Naoko Imamoto Japan 44 6.5k 0.6× 563 0.4× 586 0.5× 641 0.8× 1.0k 1.5× 115 7.8k
Heinrich Leonhardt Germany 74 17.7k 1.6× 2.0k 1.3× 1.5k 1.2× 3.1k 3.7× 2.0k 2.9× 266 22.0k
Jeffrey R. Moffitt United States 31 5.6k 0.5× 1.5k 1.0× 474 0.4× 549 0.7× 325 0.5× 55 7.8k
Jason R. Swedlow United Kingdom 51 7.1k 0.6× 1.9k 1.3× 886 0.7× 615 0.7× 3.0k 4.3× 107 9.7k

Countries citing papers authored by Xavier Darzacq

Since Specialization
Citations

This map shows the geographic impact of Xavier Darzacq's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xavier Darzacq with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xavier Darzacq more than expected).

Fields of papers citing papers by Xavier Darzacq

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xavier Darzacq. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xavier Darzacq. The network helps show where Xavier Darzacq may publish in the future.

Co-authorship network of co-authors of Xavier Darzacq

This figure shows the co-authorship network connecting the top 25 collaborators of Xavier Darzacq. A scholar is included among the top collaborators of Xavier Darzacq based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xavier Darzacq. Xavier Darzacq is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
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Maurer, Anna C., Oscar N. Whitney, Claudia Cattoglio, et al.. (2025). Double-strand break repair pathways differentially affect processing and transduction by dual AAV vectors. Nature Communications. 16(1). 1532–1532. 1 indexed citations
3.
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Graham, Thomas G.W., et al.. (2025). Bis(trifluoromethyl)carborhodamines: Highly Fluorogenic, Far-Red to Near-Infrared Dyes for Live Cell Fluorescence Microscopy, Activity-Based Sensing, and Single-Molecule Microscopy. Journal of the American Chemical Society. 147(25). 21950–21960. 1 indexed citations
5.
Esbin, Meagan N., et al.. (2025). Assembly and Dynamics of Transcription Initiation Complexes. Annual Review of Biochemistry. 94(1). 305–331. 1 indexed citations
6.
Graham, Thomas G.W., et al.. (2024). Live-cell imaging of RNA Pol II and elongation factors distinguishes competing mechanisms of transcription regulation. Molecular Cell. 84(15). 2856–2869.e9. 7 indexed citations
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Collombet, Samuel, Claire Dugast‐Darzacq, Alec Heckert, et al.. (2023). RNA polymerase II depletion from the inactive X chromosome territory is not mediated by physical compartmentalization. Nature Structural & Molecular Biology. 30(8). 1216–1223. 23 indexed citations
9.
Graham, Thomas G.W., John J. Ferrie, Gina M. Dailey, Robert Tjian, & Xavier Darzacq. (2022). Detecting molecular interactions in live-cell single-molecule imaging with proximity-assisted photoactivation (PAPA). eLife. 11. 23 indexed citations
10.
Graham, Thomas G.W., Claire Dugast‐Darzacq, Gina M. Dailey, et al.. (2021). Open-source RNA extraction and RT-qPCR methods for SARS-CoV-2 detection. PLoS ONE. 16(2). e0246647–e0246647. 23 indexed citations
11.
Herbst, Dominik A., Meagan N. Esbin, Robert K. Louder, et al.. (2021). Structure of the human SAGA coactivator complex. Nature Structural & Molecular Biology. 28(12). 989–996. 35 indexed citations
12.
Chen, Zhijie, Alan Shaw, Hugh D. Wilson, et al.. (2020). Single-molecule diffusometry reveals no catalysis-induced diffusion enhancement of alkaline phosphatase as proposed by FCS experiments. Proceedings of the National Academy of Sciences. 117(35). 21328–21335. 32 indexed citations
13.
Costantino, Lorenzo, Tsung-Han S. Hsieh, Rebecca Lamothe, Xavier Darzacq, & Douglas Koshland. (2020). Cohesin residency determines chromatin loop patterns. eLife. 9. 64 indexed citations
14.
Hollerer, Ina, Victoria Jorgensen, Amy Tresenrider, et al.. (2019). Evidence for an Integrated Gene Repression Mechanism Based on mRNA Isoform Toggling in Human Cells. G3 Genes Genomes Genetics. 9(4). 1045–1053. 20 indexed citations
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16.
Chong, Shasha, Claire Dugast‐Darzacq, Zhe Liu, et al.. (2018). Imaging dynamic and selective low-complexity domain interactions that control gene transcription. Science. 361(6400). 673 indexed citations breakdown →
17.
Mir, Mustafa, Armando Reimer, Jenna E. Haines, et al.. (2017). Dense Bicoid hubs accentuate binding along the morphogen gradient. Genes & Development. 31(17). 1784–1794. 134 indexed citations
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19.
Izeddin, Ignacio, Xavier Darzacq, & Maxime Dahan. (2011). Microscopies cellulaires à l’échelle de la molécule individuelle. médecine/sciences. 27(5). 547–552. 8 indexed citations
20.
Richard, P., et al.. (2006). Cotranscriptional Recognition of Human Intronic Box H/ACA snoRNAs Occurs in a Splicing-Independent Manner. Molecular and Cellular Biology. 26(7). 2540–2549. 62 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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