X. Chris Le

23.2k total citations · 6 hit papers
329 papers, 18.0k citations indexed

About

X. Chris Le is a scholar working on Molecular Biology, Environmental Chemistry and Health, Toxicology and Mutagenesis. According to data from OpenAlex, X. Chris Le has authored 329 papers receiving a total of 18.0k indexed citations (citations by other indexed papers that have themselves been cited), including 148 papers in Molecular Biology, 119 papers in Environmental Chemistry and 103 papers in Health, Toxicology and Mutagenesis. Recurrent topics in X. Chris Le's work include Arsenic contamination and mitigation (116 papers), Advanced biosensing and bioanalysis techniques (99 papers) and Heavy Metal Exposure and Toxicity (76 papers). X. Chris Le is often cited by papers focused on Arsenic contamination and mitigation (116 papers), Advanced biosensing and bioanalysis techniques (99 papers) and Heavy Metal Exposure and Toxicity (76 papers). X. Chris Le collaborates with scholars based in Canada, China and United States. X. Chris Le's co-authors include Xing‐Fang Li, Hongquan Zhang, Feng Li, Walter Cullen, Xiufen Lu, Hanyong Peng, Mingsheng Ma, Michael Weinfeld, Michael S. Reid and Shengwen Shen and has published in prestigious journals such as Chemical Reviews, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

X. Chris Le

319 papers receiving 17.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rolling circle amplification: a versatile tool for chemical biology, materials science and medicine

2014 888 citations X. Chris Le et al. profile →
Arsenic Binding to Proteins

2013 660 citations Xing‐Fang Li, Michael Weinfeld et al. profile →
A microRNA-initiated DNAzyme motor operating in living cells

2017 518 citations Hanyong Peng, Xing‐Fang Li et al. profile →
Human Disease Ontology 2018 update: classification, content and workflow expansion

2018 289 citations X. Chris Le et al. profile →
CRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules

2021 232 citations Wei Feng, Ashley M. Newbigging et al. profile →
The CRISPR–Cas toolbox for analytical and diagnostic assay development

2021 175 citations Wei Feng, X. Chris Le et al. profile →

Peers

Countries citing papers authored by X. Chris Le

Since Specialization

Citations

This map shows the geographic impact of X. Chris Le's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by X. Chris Le with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites X. Chris Le more than expected).

Fields of papers citing papers by X. Chris Le

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by X. Chris Le. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by X. Chris Le. The network helps show where X. Chris Le may publish in the future.

Co-authorship network of co-authors of X. Chris Le

This figure shows the co-authorship network connecting the top 25 collaborators of X. Chris Le. A scholar is included among the top collaborators of X. Chris Le based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with X. Chris Le. X. Chris Le is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Spherical Nucleic Acids‐Directed Cryosynthesis of Manganese Nanoagents for Tumor Imaging and Therapy 2025 ·Angewandte Chemie International Edition ·Wenjing Xie, (unknown), (unknown), Rui Sha, Bei Wen, Hailin Wang, Hongquan Zhang, Guohua Jia, X. Chris Le, Guibin Jiang, Hanyong Peng	1
2	Numerical study of reaction behavior affected by the aspect ratio and atmospheres for a single rod-shaped biomass char particle during oxy-fuel combustion 2025 ·Fuel ·(unknown), Zewu Zhang, (unknown), Jie Dong, X. Chris Le, Xiaoshan Li, Cong Luo, Liqi Zhang	0
3	Spherical Nucleic Acids‐Directed Cryosynthesis of Manganese Nanoagents for Tumor Imaging and Therapy 2025 ·Angewandte Chemie ·Wenjing Xie, (unknown), (unknown), Rui Sha, Bei Wen, Hailin Wang, Hongquan Zhang, Guohua Jia, X. Chris Le, Guibin Jiang, Hanyong Peng	1
4	In Vivo Evaluation of Liver Injury and Arthritis Enabled by a Nitroxyl-Activated Near-Infrared Fluorescence and Photoacoustic Dual-Modality Imaging Probe 2025 ·JACS Au ·(unknown), (unknown), (unknown), Liangliang Zhang, Yanli Luo, Shulin Zhao, X. Chris Le	0
5	Genetic variation in the FMO and GSTO gene clusters impacts arsenic metabolism in humans 2025 ·PLoS Genetics ·(unknown), Tong Lin, (unknown), Donald J. Vander Griend, Syed Emdadul Haque, Tariqul Islam, Farzana Jasmine, Muhammad G. Kibriya, Joseph H. Graziano, Lin Chen, X. Chris Le, Habibul Ahsan, Mary V. Gamble, Brandon L. Pierce	0
6	Protein-Induced DNA Dumbbell Amplification (PINDA) and its applications to food hazards detection 2024 ·Biosensors and Bioelectronics ·Bo Pang, Michael S. Reid, Wei Jia, Hanyong Peng, (unknown), Juan Li, Hongquan Zhang, X. Chris Le	3
7	Improving groundwater vulnerability assessment using machine learning 2024 ·Journal of Environmental Sciences ·Juan Fu, X. Chris Le	5
8	Label-free detection of biomolecules using inductively coupled plasma mass spectrometry (ICP-MS) 2024 ·Analytical and Bioanalytical Chemistry ·Jianyu Hu, Xiaowen Yan, X. Chris Le	12
9	RNA-Activated CRISPR/Cas12a Nanorobots Operating in Living Cells 2024 ·Journal of the American Chemical Society ·(unknown), Rui Sha, Wenjing Xie, Guangbo Qu, Hongquan Zhang, Hailin Wang, X. Chris Le, Guibin Jiang, Hanyong Peng	51
10	CRISPR/Cas13a-Responsive and RNA-Bridged DNA Hydrogel Capillary Sensor for Point-of-Care Detection of RNA 2024 ·Analytical Chemistry ·Hui Wang, Honghong Wang, (unknown), (unknown), Fu Tang, Desheng Chen, (unknown), Yongqiang Wen, X. Chris Le, Zhengping Li	8
11	Detection of Uracil-Excising DNA Glycosylases in Cancer Cell Samples Using a Three-Dimensional DNAzyme Walker 2024 ·SHILAP Revista de lepidopterología ·Jeffrey Tao, Hongquan Zhang, Michael Weinfeld, X. Chris Le	2
12	Best Practice for Identification of Classical 21-Hydroxylase Deficiency Should Include 21 Deoxycortisol Analysis with Appropriate Isomeric Steroid Separation 2023 ·International Journal of Neonatal Screening ·Ronda F. Greaves, (unknown), (unknown), (unknown), X. Chris Le, Michele A. O’Connell, (unknown), James Pitt	6
13	Multiplex Assays Enable Simultaneous Detection and Identification of SARS-CoV-2 Variants of Concern in Clinical and Wastewater Samples 2023 ·ACS Measurement Science Au ·(unknown), (unknown), Michael Joyce, D. Lorne Tyrrell, Graham Tipples, Xiaoli Pang, Xing‐Fang Li, X. Chris Le	6
14	Split Locations and Secondary Structures of a DNAzyme Critical to Binding-Assembled Multicomponent Nucleic Acid Enzymes for Protein Detection 2021 ·Analytical Chemistry ·Yiren Cao, Hongquan Zhang, X. Chris Le	28
15	Molecular Diagnosis of COVID-19: Challenges and Research Needs 2020 ·Analytical Chemistry ·Wei Feng, Ashley M. Newbigging, Connie Le, Bo Pang, Hanyong Peng, Yiren Cao, Jinjun Wu, Ghulam Abbas, Jin Song, Dianbing Wang, Mengmeng Cui, Jeffrey Tao, D. Lorne Tyrrell, Xian‐En Zhang, Hongquan Zhang, X. Chris Le	296
16	Isothermal Amplification and Ambient Visualization in a Single Tube for the Detection of SARS-CoV-2 Using Loop-Mediated Amplification and CRISPR Technology 2020 ·Analytical Chemistry ·Bo Pang, Jingyang Xu, Yan‐Ming Liu, Hanyong Peng, Wei Feng, Yiren Cao, Jinjun Wu, Huyan Xiao, Kanti Pabbaraju, Graham Tipples, Michael Joyce, Holly A. Saffran, D. Lorne Tyrrell, Hongquan Zhang, X. Chris Le	210
17	Biotransformation of arsenic-containing roxarsone by an aerobic soil bacterium Enterobacter sp. CZ-1 2019 ·Environmental Pollution ·Ke Huang, Hanyong Peng, Fan Gao, Qingqing Liu, Xiufen Lu, Qirong Shen, X. Chris Le, Fang‐Jie Zhao	30
18	N -Hydroxyarylamine O -Acetyltransferases Catalyze Acetylation of 3-Amino-4-Hydroxyphenylarsonic Acid in the 4-Hydroxy-3-Nitrobenzenearsonic Acid Transformation Pathway of Enterobacter sp. Strain CZ-1 2019 ·Applied and Environmental Microbiology ·Ke Huang, Fan Gao, X. Chris Le, Fang‐Jie Zhao	10
19	Quantitative synthesis of protein–DNA conjugates with 1 : 1 stoichiometry 2018 ·Chemical Communications ·Xiaowen Yan, Hongquan Zhang, (unknown), Hanyong Peng, Jeffrey Tao, Xing‐Fang Li, X. Chris Le	17
20	Effect of copper on the translocation and transformation of polychlorinated biphenyls in rice 2017 ·Chemosphere ·Lili Pan, Jianteng Sun, X. Chris Le, Lizhong Zhu	8

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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