William R. Kem

6.9k citations

131 papers · 5.4k indexed · 1 hit paper · h-index 38

Molecular Biology top 2%
Cellular and Molecular Neuroscience top 1%
Pharmacology top 0.5%
Biotechnology top 0.5%
Genetics top 5%

Co-authors: Robert Freedman Karen E. Stevens Vladimir M. Mahnir Ferenc Sóti Kenneth M. Blumenthal Roger L. Papke Michael W. Pennington Lynn Johnson
Topics: Nicotinic Acetylcholine Receptors Study (70 papers)Receptor Mechanisms and Signaling (34 papers)Ion channel regulation and function (22 papers)
Cited by: Biological Psychiatry Cellular and Molecular Neuroscience Pharmacology
Journals: Science Journal of Biological Chemistry The EMBO Journal
Partner nations: United States Australia Slovenia

In The Last Decade

William R. Kem

130 papers receiving 5.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The odyssey of marine pharmaceuticals: a current pipeline perspective

2010 441 citations William R. Kem et al. profile →

Peers

Countries citing papers authored by William R. Kem

Since Specialization

Citations

This map shows the geographic impact of William R. Kem's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William R. Kem with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William R. Kem more than expected).

Fields of papers citing papers by William R. Kem

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William R. Kem. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William R. Kem. The network helps show where William R. Kem may publish in the future.

Co-authorship network of co-authors of William R. Kem

This figure shows the co-authorship network connecting the top 25 collaborators of William R. Kem. A scholar is included among the top collaborators of William R. Kem based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William R. Kem. William R. Kem is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Discovery of the Nicotinic Receptor Toxin Anabaseine in a Polystiliferan Nemertean 2023 ·Toxins ·William R. Kem,James R. Rocca,Jodie V. Johnson,Juan Junoy	1
2	The nonopioid cholinergic agonist GTS-21 mitigates morphine-induced aggravation of burn injury pain together with inhibition of spinal microglia activation in young rats 2022 ·British Journal of Anaesthesia ·(unknown),(unknown),Zerong You,Hao Deng,William R. Kem,Jianren Mao,Wei Zhang,J. A. Jeevendra Martyn	8
3	Interactions of Nereistoxin and Its Analogs with Vertebrate Nicotinic Acetylcholine Receptors and Molluscan ACh Binding Proteins 2022 ·Marine Drugs ·William R. Kem,(unknown),(unknown),Hong Xing,Ferenc Sóti,Todd T. Talley,Palmer Taylor	6
4	GTS-21 attenuates loss of body mass, muscle mass, and function in rats having systemic inflammation with and without disuse atrophy 2018 ·Pflügers Archiv - European Journal of Physiology ·Stefan J. Schaller,Michio Nagashima,Martin Schönfelder,Tomoki Sasakawa,(unknown),Mohammed Abdul Sattar Khan,William R. Kem,Gerhard Schneider,Jürgen Schlegel,Heidrun Lewald,Manfred Blobner,J. A. Jeevendra Martyn	13
5	Brief Report: Initial Trial of Alpha7-Nicotinic Receptor Stimulation in Two Adult Patients with Autism Spectrum Disorder 2016 ·Journal of Autism and Developmental Disorders ·Ann Olincy,Audrey Blakeley‐Smith,Lynn Johnson,William R. Kem,Robert Freedman	27
6	Prevention of Burn-Induced Inflammatory Responses and Muscle Wasting by GTS-21, a Specific Agonist for α7 Nicotinic Acetylcholine Receptors 2016 ·Shock ·(unknown),(unknown),Shingo Yasuhara,Takahisa Goto,William R. Kem,Ronald G. Tompkins,Masao Kaneki,J. A. Jeevendra Martyn	28
7	Non-competitive Inhibition of Nicotinic Acetylcholine Receptors by Ladybird Beetle Alkaloids 2014 ·Neurochemical Research ·(unknown),Hong Xing,J. C. Braekman,William R. Kem	7
8	A new phospholipase A2 isolated from the sea anemone Urticina crassicornis - its primary structure and phylogenetic classification 2010 ·FEBS Journal ·(unknown),Igor Križaj,Jernej Šribar,Dušan Kordiš,Peter Maček,Robert Frangež,William R. Kem,Tom Turk	8
9	Proof-of-Concept Trial of an α7 Nicotinic Agonist in Schizophrenia 2006 ·Archives of General Psychiatry ·Ann Olincy,Josette G. Harris,Lynn Johnson,(unknown),(unknown),(unknown),(unknown),Gary O. Zerbe,Sherry Leonard,Karen E. Stevens,(unknown),Laura Martín,Lawrence E. Adler,Ferenc Sóti,William R. Kem,Robert Freedman	425
10	The brain α7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21) 2000 ·Behavioural Brain Research ·William R. Kem	196
11	Alzheimer's drug design based upon an invertebrate toxin (anabaseine) which is a potent nicotinic receptor agonist 1997 ·Invertebrate Neuroscience ·William R. Kem	33
12	Chemical synthesis and characterization of ShK toxin: a potent potassium channel inhibitor from a sea anemone 1995 ·International journal of peptide & protein research ·Michael W. Pennington,(unknown),(unknown),Ilya Khaytin,(unknown),D S Krafte,Robert E. Hill,Vladimir M. Mahnir,Walter A. Volberg,William Gorczyca,William R. Kem	87
13	Nicotinic cholinergic system involvement in eyeblink classical conditioning in rabbits. 1994 ·Behavioral Neuroscience ·Diana S. Woodruff‐Pak,(unknown),(unknown),William R. Kem	33
14	Limited proteolysis study of structure-function relationships in Sh I, a polypeptide neurotoxin from a sea anemone 1994 ·Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology ·Stephen A. Monks,(unknown),(unknown),Paul F. Alewood,William R. Kem,Neil H. Goss,Raymond S. Norton	7
15	A nicotinic agonist (GTS-21), eyeblink classical conditioning and nicotinic receptor binding in rabbit brain 1994 ·Brain Research ·Diana S. Woodruff‐Pak,(unknown),William R. Kem	92
16	Occurrence of a hemolytic protein toxin in nematocysts of a marine benthic hydroid, Halocordyle disticha (Goldfuss) 1992 ·Scientia Marina ·William R. Kem,Carina Östman	3
17	Synthesis and characterization of a disulfide bond isomer of omega-conotoxin GVIA 1992 ·Toxicon ·Michael W. Pennington,(unknown),Maria L. Maccecchini,William R. Kem	11
18	Binding of a radiolabeled sea anemone cytolysin to erythrocyte membranes 1989 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·James W. Doyle,William R. Kem	20
19	Separation and characterization of four different amino acid sequence variants of a sea anemone (Stichodactyla helianthus) protein cytolysin 1988 ·Toxicon ·William R. Kem,Ben M. Dunn	74
20	Unconventional amino acid sequence of the sun anemone (Stoichactis helianthus) polypeptide neurotoxin 1986 ·Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States) ·William R. Kem,Ben M. Dunn,(unknown),Michael W. Pennington,David A. Price	1

About William R. Kem

William R. Kem is a scholar working on Paleontology, Cellular and Molecular Neuroscience and Molecular Biology, having authored 131 papers that have together received 5.4k indexed citations. Recurring topics across this work include Nicotinic Acetylcholine Receptors Study (70 papers), Receptor Mechanisms and Signaling (34 papers) and Ion channel regulation and function (22 papers). The work is most often cited by research in Biological Psychiatry (174 citations), Cellular and Molecular Neuroscience (1.3k citations) and Pharmacology (1.1k citations). William R. Kem has collaborated with scholars based in United States, Australia and Slovenia. Frequent co-authors include Robert Freedman, Karen E. Stevens, Vladimir M. Mahnir, Ferenc Sóti, Kenneth M. Blumenthal, Roger L. Papke, Michael W. Pennington, Lynn Johnson, Ann Olincy and Laura Martín. Their work appears in journals such as Science, Journal of Biological Chemistry and The EMBO Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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