William N. Zagotta

12.8k total citations · 3 hit papers
111 papers, 10.1k citations indexed

About

William N. Zagotta is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, William N. Zagotta has authored 111 papers receiving a total of 10.1k indexed citations (citations by other indexed papers that have themselves been cited), including 97 papers in Molecular Biology, 71 papers in Cellular and Molecular Neuroscience and 27 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in William N. Zagotta's work include Ion channel regulation and function (71 papers), Neuroscience and Neuropharmacology Research (40 papers) and Nicotinic Acetylcholine Receptors Study (33 papers). William N. Zagotta is often cited by papers focused on Ion channel regulation and function (71 papers), Neuroscience and Neuropharmacology Research (40 papers) and Nicotinic Acetylcholine Receptors Study (33 papers). William N. Zagotta collaborates with scholars based in United States, Russia and Israel. William N. Zagotta's co-authors include Richard W. Aldrich, Toshinori Hoshi, Sharona E. Gordon, Galen E. Flynn, Steven A. Siegelbaum, Michael D. Varnum, Matthew C. Trudeau, Jie Zheng, Kimberly Matulef and N.B. Olivier and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

William N. Zagotta

108 papers receiving 10.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Biophysical and Molecular Mechanisms of Shaker Potassium Channel Inactivation

1990 1.3k citations Toshinori Hoshi, William N. Zagotta et al. profile →
Restoration of Inactivation in Mutants of Shaker Potassium Channels by a Peptide Derived from ShB

1990 621 citations William N. Zagotta, Toshinori Hoshi et al. profile →
Two types of inactivation in Shaker K+ channels: Effects of alterations in the carboxy-terminal region

1991 598 citations Toshinori Hoshi, William N. Zagotta et al. Neuron profile →

Peers

William N. Zagotta

CMN

CCM

Francisco Bezanilla United States

Gary Yellen United States

David T. Yue United States

Walter Stühmer Germany

Toshinori Hoshi United States

Youxing Jiang United States

Ramón Latorre Chile

Thomas Friedrich Germany

Masamitsu Iino Japan

Ernest B. Campbell United States

Francisco Bezanilla United States

William N. Zagotta

14.9k ×1.7

11.6k ×2.1

CMN

5.8k ×1.7

CCM

641 ×0.7

705 ×1.1

Citations per year, relative to William N. Zagotta William N. Zagotta (= 1×) peers Francisco Bezanilla

Countries citing papers authored by William N. Zagotta

Since Specialization

Citations

This map shows the geographic impact of William N. Zagotta's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William N. Zagotta with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William N. Zagotta more than expected).

Fields of papers citing papers by William N. Zagotta

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William N. Zagotta. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William N. Zagotta. The network helps show where William N. Zagotta may publish in the future.

Co-authorship network of co-authors of William N. Zagotta

This figure shows the co-authorship network connecting the top 25 collaborators of William N. Zagotta. A scholar is included among the top collaborators of William N. Zagotta based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William N. Zagotta. William N. Zagotta is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Zagotta, William N., Eric G.B. Evans, Pierce Eggan, et al.. (2024). Measuring conformational equilibria in allosteric proteins with time-resolved tmFRET. Biophysical Journal. 123(14). 2050–2062. 6 indexed citations

Jones, Chloe M., Robert J. Blizzard, Mika Munari, et al.. (2021). Genetic encoding of a highly photostable, long lifetime fluorescent amino acid for imaging in mammalian cells. Chemical Science. 12(36). 11955–11964. 37 indexed citations

Dai, Gucan, Teresa K. Aman, Frank DiMaio, & William N. Zagotta. (2021). Electromechanical coupling mechanism for activation and inactivation of an HCN channel. Nature Communications. 12(1). 2802–2802. 18 indexed citations

Flynn, Galen E. & William N. Zagotta. (2018). Insights into the molecular mechanism for hyperpolarization-dependent activation of HCN channels. Proceedings of the National Academy of Sciences. 115(34). E8086–E8095. 42 indexed citations

Collauto, Alberto, et al.. (2017). Rates and equilibrium constants of the ligand-induced conformational transition of an HCN ion channel protein domain determined by DEER spectroscopy. Physical Chemistry Chemical Physics. 19(23). 15324–15334. 33 indexed citations

Aman, Teresa K., Sharona E. Gordon, & William N. Zagotta. (2016). Regulation of CNGA1 Channel Gating by Interactions with the Membrane. Biophysical Journal. 110(3). 292a–292a. 1 indexed citations

Puljung, Michael C. & William N. Zagotta. (2013). A Secondary Structural Transition in the C-helix Promotes Gating of Cyclic Nucleotide-regulated Ion Channels. Journal of Biological Chemistry. 288(18). 12944–12956. 27 indexed citations

Taraska, Justin W., Michael C. Puljung, N.B. Olivier, Galen E. Flynn, & William N. Zagotta. (2009). Mapping the structure and conformational movements of proteins with transition metal ion FRET. Nature Methods. 6(7). 532–537. 128 indexed citations

Brelidze, Tinatin I., Anne E. Carlson, & William N. Zagotta. (2009). Absence of Direct Cyclic Nucleotide Modulation of mEAG1 and hERG1 Channels Revealed with Fluorescence and Electrophysiological Methods. Journal of Biological Chemistry. 284(41). 27989–27997. 80 indexed citations

10.

Taraska, Justin W. & William N. Zagotta. (2007). Structural dynamics in the gating ring of cyclic nucleotide–gated ion channels. Nature Structural & Molecular Biology. 14(9). 854–860. 36 indexed citations

11.

Islas, León D & William N. Zagotta. (2006). Short-range Molecular Rearrangements in Ion Channels Detected by Tryptophan Quenching of Bimane Fluorescence. The Journal of General Physiology. 128(3). 337–346. 36 indexed citations

12.

Trudeau, Matthew C. & William N. Zagotta. (2004). Dynamics of Ca2+-Calmodulin–dependent Inhibition of Rod Cyclic Nucleotide-gated Channels Measured by Patch-clamp Fluorometry. The Journal of General Physiology. 124(3). 211–223. 33 indexed citations

13.

Flynn, Galen E., J. P. Johnson, & William N. Zagotta. (2001). Cyclic nucleotide-gated channels: shedding light on the opening of a channel pore. Nature reviews. Neuroscience. 2(9). 643–651. 60 indexed citations

14.

Flynn, Galen E. & William N. Zagotta. (2001). Conformational Changes in S6 Coupled to the Opening of Cyclic Nucleotide-Gated Channels. Neuron. 30(3). 689–698. 144 indexed citations

15.

Fodor, Anthony A., Sharona E. Gordon, & William N. Zagotta. (1997). Mechanism of Tetracaine Block of Cyclic Nucleotide-gated Channels. The Journal of General Physiology. 109(1). 3–14. 53 indexed citations

16.

Li, Jun, William N. Zagotta, & Henry A. Lester. (1997). Cyclic nucleotide-gated channels: structural basis of ligand efficacy and allosteric modulation. Quarterly Reviews of Biophysics. 30(2). 177–193. 38 indexed citations

17.

Varnum, Michael D. & William N. Zagotta. (1996). Subunit interactions in the activation of cyclic nucleotide-gated ion channels. Biophysical Journal. 70(6). 2667–2679. 65 indexed citations

18.

Varnum, Michael D., et al.. (1995). Molecular mechanism for ligand discrimination of cyclic nucleotide-gated channels. Neuron. 15(3). 619–625. 160 indexed citations

19.

Hoshi, Toshinori, William N. Zagotta, & Richard W. Aldrich. (1994). Shaker potassium channel gating. I: Transitions near the open state.. The Journal of General Physiology. 103(2). 249–278. 171 indexed citations

20.

Zagotta, William N., et al.. (1989). Properties of ShB AType potassium channels expressed in Shaker mutant drosophil by germline transformation. Neuron. 3(6). 773–782. 33 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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