William Lehman

8.5k citations

169 papers · 7.0k indexed · h-index 45

Impact in

Cardiology and Cardiovascular Medicine top 0.2%
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Viral Infections and Immunology Research
Cell Biology top 0.5%
- Cellular Mechanics and Interactions

Papers in

Cardiology and Cardiovascular Medicine 146
- Cardiomyopathy and Myosin Studies 146
- Cardiovascular Effects of Exercise 64
- Viral Infections and Immunology Research 8
Cell Biology 53
- Cellular Mechanics and Interactions 45

Co-authors: Roger Craig Peter Vibert Larry S. Tobacman Albert Szent‐Györgyi Stefan Fischer John Kendrick‐Jones Xiaochuan Li Victoria Hatch
Journals: Biophysical Journal (34 papers)Journal of Molecular Biology (20 papers)Journal of Muscle Research and Cell Motility (14 papers)The Journal of General Physiology (10 papers)Archives of Biochemistry and Biophysics (9 papers)
Partner nations: United States Germany United Kingdom

In The Last Decade

William Lehman

164 papers receiving 6.9k citations

Peers

Countries citing papers authored by William Lehman

Since Specialization

Citations

This map shows the geographic impact of William Lehman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William Lehman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William Lehman more than expected).

Fields of papers citing papers by William Lehman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William Lehman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William Lehman. The network helps show where William Lehman may publish in the future.

Co-authors

The 25 scholars most cited alongside William Lehman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William Lehman Line = papers co-authored together William Lehman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	In silico and in vitro models reveal the molecular mechanisms of hypocontractility caused by TPM1 M8R Frontiers in Physiology ·Helen L. Gilburt, Daniel J. Reagan, Michael J. Rynkiewicz, William Lehman, Jeffrey R. Moore, Stuart G. Campbell	2024	0
2	Distinct mechanisms drive divergent phenotypes in hypertrophic and dilated cardiomyopathy–associated TPM1 variants Journal of Clinical Investigation ·Saiti S. Halder, Michael J. Rynkiewicz, Hermann Kaufmann, M. H. Jawadi, Constantinos Psathakis, Lorenzo R. Sewanan, Jonathan A. Kirk, Jeffrey R. Moore, William Lehman, Stuart G. Campbell	2024	2
3	Mechanisms of pathogenicity in the hypertrophic cardiomyopathy-associated TPM1 variant S215L PNAS Nexus ·Saiti S. Halder, Michael J. Rynkiewicz, Helen L. Gilburt, Lorenzo R. Sewanan, Philip R Brunner, Jeffrey R. Moore, William Lehman, Stuart G. Campbell	2023	7
4	Troponin-I–induced tropomyosin pivoting defines thin-filament function in relaxed and active muscle The Journal of General Physiology ·William Lehman, Michael J. Rynkiewicz	2023	6
5	Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin The Journal of General Physiology ·淳一佐分, Michael J. Rynkiewicz, Mads Hartvig Clausen, 邵谭, M. H. Jawadi, Esther Bullitt, Christopher M. Yengo, Jeffrey R. Moore, William Lehman	2022	11
6	A role for actin flexibility in thin filament-mediated contractile regulation and myopathy Nature Communications ·Meera Viswanathan, William M. Schmidt, Peter Franz, Michael J. Rynkiewicz, Alexandra Lauren, І. В. Калашніков, William Lehman, Douglas M. Swank, Matthias Preller, Anthony Cammarato	2020	19
7	Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments Biophysical Journal ·淳一佐分, Elumalai Pavadai, Michael J. Rynkiewicz, Jonathan Walklate, Esther Bullitt, Jeffrey R. Moore, Michael Regnier, Michael A. Geeves, William Lehman	2020	41
8	Structure of the Tpm3.1 N-Terminus: A New Target for Anti-Cancer Treatment Biophysical Journal ·Athirah Irbah Izzetya, 李佳静, Till Böcking, Peter W. Gunning, William Lehman, Michael J. Rynkiewicz	2019	1
9	Precise Binding of Tropomyosin on Actin Involves Sequence-Dependent Variance in Coiled-Coil Twisting Biophysical Journal ·William Lehman, Xiaochuan Li, Farooq Ahmad Kiani, Jeffrey R. Moore, Stuart G. Campbell, Stefan Fischer, Michael J. Rynkiewicz	2018	19
10	Distortion of the Actin A-Triad Results in Contractile Disinhibition and Cardiomyopathy Cell Reports ·Meera Viswanathan, William M. Schmidt, Michael J. Rynkiewicz, Konstantin Lukianov, Jian Gao, Joseph Katz, William Lehman, Anthony Cammarato	2017	25
11	Tarantula myosin free head regulatory light chain phosphorylation stiffens N-terminal extension, releasing it and blocking its docking back Molecular BioSystems ·Lorenzo Álamo, Xiaochuan Li, L. Michel Espinoza‐Fonseca, Antonio Pinto, David D. Thomas, William Lehman, Raúl Padrón	2015	19
12	Three-Dimensional Organization of Troponin on Cardiac Muscle Thin Filaments in the Relaxed State Biophysical Journal ·Shixin Yang, Lucian Barbu–Tudoran, Marek Orzechowski, Roger Craig, John Trinick, Howard D. White, William Lehman	2014	47
13	The flexibility of two tropomyosin mutants, D175N and E180G, that cause hypertrophic cardiomyopathy Biochemical and Biophysical Research Communications ·Xiaochuan Li, Worawit Suphamungmee, 李佳静, Michael A. Geeves, Steven B. Marston, Stefan Fischer, William Lehman	2012	43
14	Electron Microscopy and 3D Reconstruction of F-Actin Decorated with Cardiac Myosin-Binding Protein C (cMyBP-C) Journal of Molecular Biology ·Ji Young Mun, James Gulick, Jeffrey Robbins, John L. Woodhead, William Lehman, Roger Craig	2011	61
15	The recruitment of acetylated and unacetylated tropomyosin to distinct actin polymers permits the discrete regulation of specific myosins in fission yeast Journal of Cell Science ·Arthur T. Coulton, Daniel A. East, Agnieszka Galińska-Rakoczy, William Lehman, Daniel P. Mulvihill	2010	72
16	Precise Modulation of Tropomyosin Polymer Length is Crucial for its Association with Actin and Ability to Regulate Myosin Function Biophysical Journal ·Mariel Sallee, Duncan Sousa, William Lehman, Daniel P. Mulvihill	2010	1
17	Electron Microscopy and Persistence Length Analysis of Semi-Rigid Smooth Muscle Tropomyosin Strands Biophysical Journal ·Duncan Sousa, Anthony Cammarato, Р. БАТЫРБАЕВ, Philip Graceffa, Larry S. Tobacman, Xiaochuan Li, William Lehman	2010	43
18	EM and 3D-Reconstruction of Thin Filaments Reconstituted with Truncated Troponin I Associated with Myocardial Stunning Biophysical Journal ·Agnieszka Galińska-Rakoczy, Victoria Hatch, Roger Craig, Anne M. Murphy, Jennifer E. Van Eyk, Mun-Chong Sin, William Lehman, D. Brian Foster	2009	1
19	Drosophila Muscle Regulation Characterized by Electron Microscopy and Three-Dimensional Reconstruction of Thin Filament Mutants Biophysical Journal ·Anthony Cammarato, Victoria Hatch, Judith D. Saide, Roger Craig, John C. Sparrow, Larry S. Tobacman, William Lehman	2004	38
20	Three-dimensional image reconstruction of reconstituted smooth muscle thin filaments: effects of caldesmon Biophysical Journal ·Julie L. Hodgkinson, Steven B. Marston, Roger Craig, Peter Vibert, William Lehman	1997	55

About William Lehman

William Lehman is a scholar working on Cardiology and Cardiovascular Medicine, Cell Biology, Molecular Biology, Aging and Atomic and Molecular Physics, and Optics, having authored 169 papers that have together received 7.0k indexed citations. Recurring topics across this work include Cardiomyopathy and Myosin Studies (146 papers), Muscle Physiology and Disorders (69 papers), Cardiovascular Effects of Exercise (64 papers), Cellular Mechanics and Interactions (45 papers), Force Microscopy Techniques and Applications (35 papers), Genetic Neurodegenerative Diseases (12 papers), Viral Infections and Immunology Research (8 papers) and RNA Research and Splicing (7 papers). The work is most often cited by research in Cardiology and Cardiovascular Medicine (5.2k citations), Cell Biology (1.8k citations), Structural Biology (131 citations), Molecular Biology (4.2k citations) and Aging (90 citations). William Lehman has collaborated with scholars based in United States, Germany and United Kingdom. Frequent co-authors include Roger Craig, Peter Vibert, Larry S. Tobacman, Albert Szent‐Györgyi, Stefan Fischer, John Kendrick‐Jones, Xiaochuan Li, Victoria Hatch, Andrew G. Szent‐Györgyi and Steven B. Marston. Their work appears in journals such as Biophysical Journal, Journal of Molecular Biology, Journal of Muscle Research and Cell Motility, The Journal of General Physiology and Archives of Biochemistry and Biophysics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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