William J. Spain

5.0k total citations · 2 hit papers
43 papers, 3.7k citations indexed

About

William J. Spain is a scholar working on Cellular and Molecular Neuroscience, Cognitive Neuroscience and Molecular Biology. According to data from OpenAlex, William J. Spain has authored 43 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 37 papers in Cellular and Molecular Neuroscience, 29 papers in Cognitive Neuroscience and 18 papers in Molecular Biology. Recurrent topics in William J. Spain's work include Neural dynamics and brain function (27 papers), Neuroscience and Neuropharmacology Research (23 papers) and Neuroscience and Neural Engineering (19 papers). William J. Spain is often cited by papers focused on Neural dynamics and brain function (27 papers), Neuroscience and Neuropharmacology Research (23 papers) and Neuroscience and Neural Engineering (19 papers). William J. Spain collaborates with scholars based in United States, Russia and Italy. William J. Spain's co-authors include P. C. Schwindt, W. E. Crill, Matthew H. Higgs, Adrienne L. Fairhall, Brian N. Lundstrom, Robert C. Foehring, M. C. Chubb, Massimo Mantegazza, Kimberly A. Burton and G. Stanley McKnight and has published in prestigious journals such as Nature, Journal of Neuroscience and Nature Neuroscience.

In The Last Decade

William J. Spain

43 papers receiving 3.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

2006 823 citations Frank H. Yu, Massimo Mantegazza et al. Nature Neuroscience profile →
Fractional differentiation by neocortical pyramidal neurons

2008 528 citations Brian N. Lundstrom, Matthew H. Higgs et al. Nature Neuroscience profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
William J. Spain United States	26	2.5k	1.7k	1.3k	546	480	43	3.7k
Maxim Bazhenov United States	41	3.2k 1.3×	3.3k 1.9×	494 0.4×	305 0.6×	484 1.0×	126	4.9k
José Luis Pérez Velázquez Canada	43	2.3k 0.9×	2.1k 1.2×	1.5k 1.2×	300 0.5×	273 0.6×	116	4.8k
Imre Vida Germany	34	4.5k 1.8×	3.8k 2.2×	1.4k 1.1×	186 0.3×	264 0.6×	88	5.9k
Michael J. Gutnick Israel	41	5.6k 2.2×	3.5k 2.1×	2.4k 1.9×	706 1.3×	289 0.6×	83	7.4k
Marlene Bartos Germany	31	4.0k 1.6×	3.7k 2.2×	922 0.7×	184 0.3×	256 0.5×	61	5.4k
Fiona E. N. LeBeau United Kingdom	35	3.4k 1.4×	3.6k 2.1×	1.1k 0.9×	234 0.4×	263 0.5×	65	5.0k
Thierry Bal United States	18	2.7k 1.1×	2.7k 1.6×	884 0.7×	211 0.4×	192 0.4×	18	3.8k
Gilad Silberberg Sweden	38	4.7k 1.9×	4.3k 2.5×	1.8k 1.4×	141 0.3×	202 0.4×	83	7.2k
Edgar Buhl United Kingdom	28	3.5k 1.4×	2.9k 1.7×	889 0.7×	120 0.2×	187 0.4×	53	4.5k

Countries citing papers authored by William J. Spain

Since Specialization

Citations

This map shows the geographic impact of William J. Spain's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William J. Spain with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William J. Spain more than expected).

Fields of papers citing papers by William J. Spain

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William J. Spain. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William J. Spain. The network helps show where William J. Spain may publish in the future.

Co-authorship network of co-authors of William J. Spain

This figure shows the co-authorship network connecting the top 25 collaborators of William J. Spain. A scholar is included among the top collaborators of William J. Spain based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William J. Spain. William J. Spain is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Li, Ning, Wucheng Tao, Yang Liu, William J. Spain, & Christopher B. Ransom. (2022). GABA-B receptors enhance GABA-A receptor currents by modulation of membrane trafficking in dentate gyrus granule cells. Neuroscience Letters. 773. 136481–136481. 5 indexed citations

Guan, Dongxu, et al.. (2021). Kv2.1 Potassium Channels Regulate Repetitive Burst Firing in Extratelencephalic Neocortical Pyramidal Neurons. Cerebral Cortex. 32(5). 1055–1076. 13 indexed citations

Ransom, Christopher B., Zu‐Cheng Ye, William J. Spain, & George B. Richerson. (2017). Modulation of Tonic GABA Currents by Anion Channel and Connexin Hemichannel Antagonists. Neurochemical Research. 42(9). 2551–2559. 15 indexed citations

Tao, Wucheng, Matthew H. Higgs, William J. Spain, & Christopher B. Ransom. (2013). Postsynaptic GABA_BReceptors Enhance Extrasynaptic GABA_AReceptor Function in Dentate Gyrus Granule Cells. Journal of Neuroscience. 33(9). 3738–3743. 54 indexed citations

Higgs, Matthew H., Marina S. Kuznetsova, & William J. Spain. (2012). Adaptation of Spike Timing Precision Controls the Sensitivity to Interaural Time Difference in the Avian Auditory Brainstem. Journal of Neuroscience. 32(44). 15489–15494. 6 indexed citations

Brown, Andrew D., Marina S. Kuznetsova, William J. Spain, & G. Christopher Stecker. (2012). Frequency-specific, location-nonspecific adaptation of interaural time difference sensitivity. Hearing Research. 291(1-2). 52–56. 4 indexed citations

Ransom, Christopher B., Wucheng Tao, Yuanming Wu, William J. Spain, & George B. Richerson. (2012). Rapid regulation of tonic GABA currents in cultured rat hippocampal neurons. Journal of Neurophysiology. 109(3). 803–812. 17 indexed citations

Higgs, Matthew H. & William J. Spain. (2011). Kv1 channels control spike threshold dynamics and spike timing in cortical pyramidal neurones. The Journal of Physiology. 589(21). 5125–5142. 76 indexed citations

Lundstrom, Brian N., Michael Famulare, L. B. Sorensen, William J. Spain, & Adrienne L. Fairhall. (2009). Sensitivity of firing rate to input fluctuations depends on time scale separation between fast and slow variables in single neurons. Journal of Computational Neuroscience. 27(2). 277–290. 40 indexed citations

10.

Higgs, Matthew H. & William J. Spain. (2009). Conditional Bursting Enhances Resonant Firing in Neocortical Layer 2–3 Pyramidal Neurons. Journal of Neuroscience. 29(5). 1285–1299. 68 indexed citations

11.

Kuznetsova, Marina S., Matthew H. Higgs, & William J. Spain. (2008). Adaptation of Firing Rate and Spike-Timing Precision in the Avian Cochlear Nucleus. Journal of Neuroscience. 28(46). 11906–11915. 24 indexed citations

12.

Lundstrom, Brian N., Matthew H. Higgs, William J. Spain, & Adrienne L. Fairhall. (2008). Fractional differentiation by neocortical pyramidal neurons. Nature Neuroscience. 11(11). 1335–1342. 528 indexed citations breakdown →

13.

Olavarría, Jaime F., J. F. M. van Brederode, & William J. Spain. (2007). Retinal influences induce bidirectional changes in the kinetics of N-methyl-d-aspartate receptor-mediated responses in striate cortex cells during postnatal development. Neuroscience. 148(3). 683–699. 4 indexed citations

14.

Yu, Frank H., Massimo Mantegazza, Ruth E. Westenbroek, et al.. (2006). Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. Nature Neuroscience. 9(9). 1142–1149. 823 indexed citations breakdown →

15.

Higgs, Matthew H., Sean J. Slee, & William J. Spain. (2006). Diversity of Gain Modulation by Noise in Neocortical Neurons: Regulation by the Slow Afterhyperpolarization Conductance. Journal of Neuroscience. 26(34). 8787–8799. 101 indexed citations

16.

Rho, Jong M., et al.. (2004). Effects of flunarizine on spontaneous synaptic currents in rat neocortex. Naunyn-Schmiedeberg s Archives of Pharmacology. 370(3). 176–182. 4 indexed citations

17.

Yang, Yaxiong, Gregory A. Kinney, William J. Spain, John C.S. Breitner, & David G. Cook. (2004). Presenilin‐1 and intracellular calcium stores regulate neuronal glutamate uptake. Journal of Neurochemistry. 88(6). 1361–1372. 22 indexed citations

18.

Cook, Daniel L., P. C. Schwindt, Lucinda A. Grande, & William J. Spain. (2003). Synaptic depression in the localization of sound. Nature. 421(6918). 66–70. 142 indexed citations

19.

Brederode, J. F. M. van, Jong M. Rho, R. Cerne, B.L. Tempel, & William J. Spain. (2001). Evidence of altered inhibition in layer V pyramidal neurons from neocortex of Kcna1-null mice. Neuroscience. 103(4). 921–929. 23 indexed citations

20.

Schwindt, P. C., William J. Spain, & W. E. Crill. (1988). Influence of anomalous rectifier activation on afterhyperpolarizations of neurons from cat sensorimotor cortex in vitro. Journal of Neurophysiology. 59(2). 468–481. 50 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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