Thomas R. Tephly

14.2k total citations · 2 hit papers
175 papers, 10.4k citations indexed

About

Thomas R. Tephly is a scholar working on Pharmacology, Molecular Biology and Pathology and Forensic Medicine. According to data from OpenAlex, Thomas R. Tephly has authored 175 papers receiving a total of 10.4k indexed citations (citations by other indexed papers that have themselves been cited), including 74 papers in Pharmacology, 72 papers in Molecular Biology and 42 papers in Pathology and Forensic Medicine. Recurrent topics in Thomas R. Tephly's work include Pharmacogenetics and Drug Metabolism (72 papers), Alcohol Consumption and Health Effects (41 papers) and Porphyrin Metabolism and Disorders (23 papers). Thomas R. Tephly is often cited by papers focused on Pharmacogenetics and Drug Metabolism (72 papers), Alcohol Consumption and Health Effects (41 papers) and Porphyrin Metabolism and Disorders (23 papers). Thomas R. Tephly collaborates with scholars based in United States, United Kingdom and Australia. Thomas R. Tephly's co-authors include Christopher D. King, Gladys R. Rios, Birgit L. Coffman, Kenneth E. McMartin, A.B. Makar, Brian Burchell, Mitchell D. Green, Gilbert J. Mannering, Peter I. Mackenzie and Charles N. Falany and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Thomas R. Tephly

175 papers receiving 9.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

1997 985 citations Peter I. Mackenzie, Ida S. Owens et al. Pharmacogenetics profile →
Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.

1998 541 citations Christopher D. King, Thomas R. Tephly et al. Journal of Clinical Investigation profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Thomas R. Tephly United States	54	4.2k	4.2k	2.3k	1.9k	1.1k	175	10.4k
David J. Jollow United States	37	7.2k 1.7×	2.7k 0.6×	2.4k 1.1×	775 0.4×	914 0.9×	94	12.7k
Dominique Pessayre France	69	5.0k 1.2×	4.2k 1.0×	2.1k 0.9×	697 0.4×	1.6k 1.5×	248	14.6k
James R. Gillette United States	58	7.8k 1.8×	4.0k 1.0×	2.7k 1.2×	726 0.4×	957 0.9×	184	14.8k
Attallah Kappas United States	70	2.2k 0.5×	10.7k 2.6×	1.2k 0.5×	4.8k 2.5×	1.7k 1.6×	377	17.0k
Sidney D. Nelson United States	53	6.5k 1.5×	2.9k 0.7×	2.4k 1.0×	540 0.3×	515 0.5×	213	10.8k
Neil Kaplowitz United States	95	9.2k 2.2×	8.4k 2.0×	4.4k 1.9×	1.5k 0.8×	3.7k 3.5×	314	30.6k
Olavi Pelkonen Finland	61	6.4k 1.5×	3.9k 0.9×	2.8k 1.2×	1.4k 0.7×	354 0.3×	291	13.2k
Jeffrey R. Idle United Kingdom	70	6.4k 1.5×	6.4k 1.5×	3.3k 1.4×	1.4k 0.7×	929 0.9×	270	15.7k
Gérard Siest France	61	2.5k 0.6×	4.1k 1.0×	1.7k 0.7×	1.2k 0.6×	1.1k 1.1×	519	14.5k
Ivar Roots Germany	68	5.9k 1.4×	4.7k 1.1×	4.9k 2.1×	3.3k 1.7×	408 0.4×	253	16.4k

Countries citing papers authored by Thomas R. Tephly

Since Specialization

Citations

This map shows the geographic impact of Thomas R. Tephly's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas R. Tephly with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas R. Tephly more than expected).

Fields of papers citing papers by Thomas R. Tephly

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas R. Tephly. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas R. Tephly. The network helps show where Thomas R. Tephly may publish in the future.

Co-authorship network of co-authors of Thomas R. Tephly

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas R. Tephly. A scholar is included among the top collaborators of Thomas R. Tephly based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas R. Tephly. Thomas R. Tephly is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Xu, Lin, et al.. (2006). N-GLUCURONIDATION OF PERFLUOROOCTANESULFONAMIDE BY HUMAN, RAT, DOG, AND MONKEY LIVER MICROSOMES AND BY EXPRESSED RAT AND HUMAN UDP-GLUCURONOSYLTRANSFERASES. Drug Metabolism and Disposition. 34(8). 1406–1410. 54 indexed citations

Rios, Gladys R. & Thomas R. Tephly. (2002). Inhibition and Active Sites of UDP-Glucuronosyltransferases 2B7 and 1A1.. Drug Metabolism and Disposition. 30(12). 1364–1367. 42 indexed citations

Little, Joanna M., et al.. (2001). Glucuronidation of Linoleic Acid Diols by Human Microsomal and Recombinant UDP-Glucuronosyltransferases: Identification of UGT2B7 as the Major Isoform Involved. Archives of Biochemistry and Biophysics. 389(2). 176–186. 18 indexed citations

Rios, Gladys R., et al.. (1999). Folate and Folate-Dependent Enzymes Associated with Rat CNS Development. Developmental Neuroscience. 21(1). 29–35. 10 indexed citations

Tephly, Thomas R., et al.. (1997). Metabolism of Endobiotics and Xenobiotics by UDP-Glucuronosyltransferase. Advances in pharmacology. 42. 343–346. 13 indexed citations

Mackenzie, Peter I., Ida S. Owens, Brian Burchell, et al.. (1997). The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics. 7(4). 255–269. 985 indexed citations breakdown →

Tephly, Thomas R., et al.. (1997). Folate and 10-formyltetrahydrofolate dehydrogenase (FDH) expression in the central nervous system of the mature rat. Brain Research. 766(1-2). 195–204. 30 indexed citations

Debinski, Henry, Peter I. Mackenzie, M. L. Mashford, et al.. (1996). UDP glucuronosyltransferase in the cirrhotic rat liver. Journal of Gastroenterology and Hepatology. 11(4). 373–379. 16 indexed citations

Bishop, Warren P., et al.. (1995). Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides.. Drug Metabolism and Disposition. 23(3). 299–302. 112 indexed citations

10.

Green, M.D., et al.. (1995). Cloning and Expression of a Rat-Liver Phenobarbital-Inducible UDP-Glucuronosyltransferase (2B12) with Specificity for Monoterpenoid Alcohols. Archives of Biochemistry and Biophysics. 322(2). 460–468. 42 indexed citations

11.

Tephly, Thomas R., Birgit L. Coffman, Gladys R. Rios, et al.. (1994). Studies on the glucuronidation of dopamine D-1 receptor antagonists, SCH 39166 and SCH 23390, by human liver microsomes.. Drug Metabolism and Disposition. 22(5). 713–718. 5 indexed citations

12.

Tephly, Thomas R., et al.. (1994). Detection and quantification of 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) in rat retina, optic nerve, and brain. Life Sciences. 54(22). PL395–PL399. 12 indexed citations

13.

Coffman, Birgit L., et al.. (1991). Purification and properties of a rat liver phenobarbital-inducible 4-hydroxybiphenyl UDP-glucuronosyltransferase.. Molecular Pharmacology. 40(1). 80–84. 13 indexed citations

14.

Makar, A.B., Thomas R. Tephly, Gönül Şahin, & Gary D. Osweiler. (1990). Formate metabolism in young swine. Toxicology and Applied Pharmacology. 105(2). 315–320. 20 indexed citations

15.

Tephly, Thomas R., et al.. (1988). Endogenous Substrates for Udp-Glucuronosyl-Transferases. Xenobiotica. 18(11). 1201–1210. 46 indexed citations

16.

Radomińska-Pyrek, A, Piotr Zimniak, Yacoub M. Irshaid, et al.. (1987). Glucuronidation of 6 alpha-hydroxy bile acids by human liver microsomes.. Journal of Clinical Investigation. 80(1). 234–241. 82 indexed citations

17.

Toribara, Neil W., Robert B. Kirkpatrick, Charles N. Falany, Douglas R. LaBrecque, & Thomas R. Tephly. (1984). Sequential changes in primary rat hepatocyte monolayer culture udp glucuronyltransferase activities show a preneoplastic like pattern. Hepatology. 4(5). 1054. 5 indexed citations

18.

Tukey, Robert H., Robert Robinson, Bruce A. Holm, Charles N. Falany, & Thomas R. Tephly. (1982). A procedure for the rapid separation and purification of UDP-glucuronosyltransferases from rabbit liver microsomes.. Drug Metabolism and Disposition. 10(2). 97–101. 11 indexed citations

19.

Tephly, Thomas R., G Wagner, Richard M. Sedman, & Walter N. Piper. (1978). Effects of metals on heme biosynthesis and metabolism.. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 37(1). 35–9. 27 indexed citations

20.

Sánchez, M. E., et al.. (1975). Morphine metabolism. III. Solubilization and separation of morphine and p-nitrophenol uridine diphosphoglucuronyltransferases.. PubMed. 11(2). 236–40. 26 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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