Thomas P. Brent

4.3k total citations
87 papers, 3.7k citations indexed

About

Thomas P. Brent is a scholar working on Molecular Biology, Cancer Research and Genetics. According to data from OpenAlex, Thomas P. Brent has authored 87 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 82 papers in Molecular Biology, 24 papers in Cancer Research and 11 papers in Genetics. Recurrent topics in Thomas P. Brent's work include DNA Repair Mechanisms (52 papers), Epigenetics and DNA Methylation (32 papers) and DNA and Nucleic Acid Chemistry (21 papers). Thomas P. Brent is often cited by papers focused on DNA Repair Mechanisms (52 papers), Epigenetics and DNA Methylation (32 papers) and DNA and Nucleic Acid Chemistry (21 papers). Thomas P. Brent collaborates with scholars based in United States, Canada and United Kingdom. Thomas P. Brent's co-authors include Joanna S. Remack, A.R. Crathorn, Linda C. Harris, Peter J. Houghton, J. J. Roberts, Mathew A. von Wronski, J. A. V. Butler, B. Singer, Rebecca P. Danam and Janet A. Houghton and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Thomas P. Brent

87 papers receiving 3.5k citations

Peers

Thomas P. Brent

GENET

ONCOL

GENET

Maria G. Pallavicini United States

Raymond Taetle United States

Jordan M. Cummins United States

Rufus S. Day United States

Anne W. Hamburger United States

Edward Fox United States

Alwin Krämer Germany

Warren Fiskus United States

Arrigo De Benedetti United States

Ian Cheong United States

Maria G. Pallavicini United States

Thomas P. Brent

1.8k ×0.6

549 ×0.5

348 ×0.5

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877 ×1.4

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393 ×1.0

GENET

Citations per year, relative to Thomas P. Brent Thomas P. Brent (= 1×) peers Maria G. Pallavicini

Countries citing papers authored by Thomas P. Brent

Since Specialization

Citations

This map shows the geographic impact of Thomas P. Brent's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas P. Brent with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas P. Brent more than expected).

Fields of papers citing papers by Thomas P. Brent

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas P. Brent. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas P. Brent. The network helps show where Thomas P. Brent may publish in the future.

Co-authorship network of co-authors of Thomas P. Brent

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas P. Brent. A scholar is included among the top collaborators of Thomas P. Brent based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas P. Brent. Thomas P. Brent is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Remack, Joanna S., et al.. (2004). 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine (VNP40101M): II. Role of O 6 -alkylguanine-DNA alkyltransferase in cytotoxicity. Cancer Chemotherapy and Pharmacology. 53(4). 288–295. 27 indexed citations

Danam, Rebecca P., et al.. (2001). Heterogeneous methylation of the O6-methylguanine-DNA methyltransferase promoter in immortalized IMR90 cell lines. International Journal of Oncology. 18(6). 1187–93. 17 indexed citations

Remack, Joanna S., et al.. (1999). Extraneuronal monoamine transporter expression and DNA repair vis-à-vis 2-chloroethyl-3-sarcosinamide-1-nitrosourea cytotoxicity in human tumor cell lines.. PubMed. 5(12). 4186–90. 10 indexed citations

Herfarth, Klaus, Thomas P. Brent, Rebecca P. Danam, et al.. (1999). A specific CpG methylation pattern of theMGMT promoter region associated with reduced MGMT expression in primary colorectal cancers. Molecular Carcinogenesis. 24(2). 90–98. 68 indexed citations

Chen, Zhong-Ping, Areti Malapetsa, Daniela Di Marcantonio, et al.. (1997). Evidence for Nucleotide Excision Repair as a Modifying Factor ofO6-Methylguanine-DNA Methyltransferase-Mediated Innate Chloroethylnitrosourea Resistance in Human Tumor Cell Lines. Molecular Pharmacology. 52(5). 815–820. 36 indexed citations

Roy, Rahul, et al.. (1995). A comparative study of the biochemical properties of human and mouse recombinant O⁶-methylguanine-DNA methyltransferases. Carcinogenesis. 16(2). 405–411. 10 indexed citations

Wronski, Mathew A. von, et al.. (1995). Localization of methylation sites in the human O⁶-methylguanine-DNA methyltransferase promoter: correlation with gene suppression. Carcinogenesis. 16(6). 1385–1390. 46 indexed citations

Harris, Linda C., Joanna S. Remack, & Thomas P. Brent. (1994). Identification of a 59 bp enhancer located at the first exon/intron boundary of the human O⁶-methylguanine DNA methyltransferease gene. Nucleic Acids Research. 22(22). 4614–4619. 37 indexed citations

Wronski, Mathew A. von & Thomas P. Brent. (1994). Effect of 5-azacytidine on expression of the human DNA repair enzyme O⁶-methylguanine-DNA methyltransferase. Carcinogenesis. 15(4). 577–582. 24 indexed citations

10.

Natarajan, A.T., F. Darroudi, Marcus B. Valentine, et al.. (1992). Chromosomal localization of human O⁶-methylguanine-DNA methyltransferase (MGMT) gene by in situ hybridization. Mutagenesis. 7(1). 83–85. 52 indexed citations

11.

Shiota, Susumu, Mathew A. von Wronski, Keizo Tano, et al.. (1992). Characterization of cDNA encoding mouse DNA repair protein O6-methylguanine-DNA methyltransferase and high-level expression of the wild-type and mutant proteins in E. coli. Biochemistry. 31(7). 1897–1903. 19 indexed citations

12.

Tano, Keizo, Susumu Shiota, Joanna S. Remack, et al.. (1991). The origin of O6-methylguanine-DNA methyltransferase in Chinese hamster overy cells transfected with human DNA. Mutation Research/DNA Repair. 255(2). 175–182. 8 indexed citations

13.

Harris, Linda C., et al.. (1990). Evidence that covalent complex formation between BCNU treated oligonucleotides andE.colialkyItransferases requires the O⁶-alkylguanine function. Nucleic Acids Research. 18(13). 3961–3966. 15 indexed citations

14.

Schold, S. Clifford, Thomas P. Brent, Eric von Hofe, et al.. (1989). O6-Alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts. Journal of neurosurgery. 70(4). 573–577. 100 indexed citations

15.

Gallagher, Patricia E., et al.. (1989). Cytosine photoproduct-DNA glycosylase in Escherichia coli and cultured human cells. Biochemistry. 28(4). 1488–1492. 20 indexed citations

16.

Wronski, Mathew A. von, Darell D. Bigner, & Thomas P. Brent. (1989). Expression of O⁶-Alkylguanine-DNA Alkyltransferase in Mer⁺ and Mer^- Human Cell Extracts Probed with Specific Monoclonal Antibodies. PubMed. 1(5). 323–327. 8 indexed citations

17.

Gallagher, Patricia E., et al.. (1989). A Human Endonuclease Incises Ultraviolet‐Irradiated DNA at Cytosines and Oxidized DNA at Thymines. Molecular Carcinogenesis. 2(4). 188–191. 3 indexed citations

18.

Gallagher, Patricia E., et al.. (1989). WAVELENGTH DEPENDENCE OF DNA INCISION BY A HUMAN ULTRAVIOLET ENDONUCLEASE. Photochemistry and Photobiology. 49(3). 363–367. 7 indexed citations

19.

Brent, Thomas P. & Joanna S. Remack. (1988). Formation of covalent complexes between humanO⁶alkyltransferase and BCNU-treated defined length synthetic oligodeoxynucleotides. Nucleic Acids Research. 16(14). 6779–6788. 50 indexed citations

20.

Brent, Thomas P., et al.. (1971). Repair and Replication of X-irradiated HeLa Cell DNA. International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine. 19(4). 339–348. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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