Thomas C. Chen

10.6k citations

176 papers · 5.9k indexed · h-index 43

Impact in

Genetics top 1%
- Glioma Diagnosis and Treatment
Cell Biology top 1%
- Endoplasmic Reticulum Stress and Disease

Papers in ⓘ

Molecular Biology 63
Genetics 52
- Glioma Diagnosis and Treatment 48

Co-authors: Axel H. Schönthal (76 shared papers)Florence M. Hofman (65 shared papers)Stan G. Louie (17 shared papers)Weijun Wang (39 shared papers)Peter Pyrko (6 shared papers)Nicos A. Petasis (14 shared papers)Encouse B. Golden (11 shared papers)Adel Kardosh (12 shared papers)
Journals: Neurosurgical FOCUS (21 papers)Journal of neurosurgery (15 papers)Neurosurgery (14 papers)Cancer Letters (11 papers)Molecular Cancer Therapeutics (7 papers)
Partner nations: United States China Taiwan

In The Last Decade

Thomas C. Chen

172 papers receiving 5.8k citations

Peers

Countries citing papers authored by Thomas C. Chen

Since Specialization

Citations

This map shows the geographic impact of Thomas C. Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas C. Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas C. Chen more than expected).

Fields of papers citing papers by Thomas C. Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas C. Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas C. Chen. The network helps show where Thomas C. Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Thomas C. Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Thomas C. Chen Line = papers co-authored together Thomas C. Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 176 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The Unfolded Protein Response Regulator GRP78/BiP as a Novel Target for Increasing Chemosensitivity in Malignant Gliomas Cancer Research ·Peter Pyrko, Axel H. Schönthal, Florence M. Hofman, Thomas C. Chen, Amy S. Lee	2007	377
2	Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid–based proteasome inhibitors Blood ·Encouse B. Golden, Philip Y. Lam, Adel Kardosh, Kevin J. Gaffney, Enrique Cadenas, Stan G. Louie, Nicos A. Petasis, Thomas C. Chen, Axel H. Schönthal	2009	206
3	Experience in the surgical management of 82 symptomatic herniated thoracic discs and review of the literature Journal of neurosurgery ·Charles B. Stillerman, Thomas C. Chen, William T. Couldwell, Wei Zhang, Martin H. Weiss	1998	180
4	Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines FEBS Letters ·William T. Couldwell, David R. Hinton, Shikun He, Thomas C. Chen, Ibrahim Sebat, Martin H. Weiss, Ronald E. Law	1994	176
5	Fasting Enhances the Response of Glioma to Chemo- and Radiotherapy PLoS ONE ·Fernando M. Safdie, Sebastian Brandhorst, Min Wei, Weijun Wang, Changhan Lee, Saewon Hwang, Peter S. Conti, Thomas C. Chen, Valter D. Longo	2012	159
6	Quinoline-based antimalarial drugs: a novel class of autophagy inhibitors Neurosurgical FOCUS ·Encouse B. Golden, Hee‐Yeon Cho, Florence M. Hofman, Stan G. Louie, Axel H. Schönthal, Thomas C. Chen	2015	142
7	Chloroquine enhances temozolomide cytotoxicity in malignant gliomas by blocking autophagy Neurosurgical FOCUS ·Encouse B. Golden, Hee‐Yeon Cho, Ardeshir Jahanian, Florence M. Hofman, Stan G. Louie, Axel H. Schönthal, Thomas C. Chen	2014	138
8	Stress Chaperone GRP78/BiP Confers Chemoresistance to Tumor-Associated Endothelial Cells Molecular Cancer Research ·Jenilyn J. Virrey, Dezheng Dong, Caryn Stiles, John B. Patterson, Ligaya Pen, Min Ni, Axel H. Schönthal, Thomas C. Chen, Florence M. Hofman, Amy S. Lee	2008	138
9	Tumor vasculature and glioma stem cells: Contributions to glioma progression Cancer Letters ·Niyati Jhaveri, Thomas C. Chen, Florence M. Hofman	2014	118
10	Aggravated Endoplasmic Reticulum Stress as a Basis for Enhanced Glioblastoma Cell Killing by Bortezomib in Combination with Celecoxib or Its Non-Coxib Analogue, 2,5-Dimethyl-Celecoxib Cancer Research ·Adel Kardosh, Encouse B. Golden, Peter Pyrko, Jasim Uddin, Florence M. Hofman, Thomas C. Chen, Stan G. Louie, Nicos A. Petasis, Axel H. Schönthal	2008	113
11	Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib Molecular Cancer Therapeutics ·Peter Pyrko, Adel Kardosh, Yen‐Ting Liu, Nathaniel Soriano, Wenyong Xiong, Robert H. Chow, Jasim Uddin, Nicos A. Petasis, Austin K. Mircheff, Robert A. Farley, Stan G. Louie, Thomas C. Chen, Axel H. Schönthal	2007	111
12	HIV-1 Protease Inhibitors Nelfinavir and Atazanavir Induce Malignant Glioma Death by Triggering Endoplasmic Reticulum Stress Cancer Research ·Peter Pyrko, Adel Kardosh, Weijun Wang, Wenyong Xiong, Axel H. Schönthal, Thomas C. Chen	2007	110
13	Single-Shot, Multicycle Suicide Gene Therapy by Replication-Competent Retrovirus Vectors Achieves Long-Term Survival Benefit in Experimental Glioma Molecular Therapy ·Chien-Kuo Tai, Wei Jun Wang, Thomas C. Chen, Noriyuki Kasahara	2005	95
14	Preclinical development and clinical use of perillyl alcohol for chemoprevention and cancer therapy. PubMed ·Thomas C. Chen, Clóvis Orlando da Fonseca, Axel H. Schönthal	2015	95
15	Inhibition of autophagy and induction of breast cancer cell death by mefloquine, an antimalarial agent Cancer Letters ·Natasha Sharma, Simmy Thomas, Encouse B. Golden, Florence M. Hofman, Thomas C. Chen, Nicos A. Petasis, Axel H. Schönthal, Stan G. Louie	2012	94
16	Magnetic Resonance Imaging and Pathological Correlates of Meningiomas Neurosurgery ·Thomas C. Chen, Chi‐Shing Zee, Carol A. Miller, Martin H. Weiss, Gordon Tang, Lawrence S. Chin, Michael L. Levy, Michael L.J. Apuzzo	1992	94
17	The transfacet pedicle-sparing approach for thoracic disc removal: cadaveric morphometric analysis and preliminary clinical experience Journal of neurosurgery ·Charles B. Stillerman, Thomas C. Chen, J. Diaz Day, William T. Couldwell, Martin H. Weiss	1995	92
18	Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models Cancer Letters ·Thomas C. Chen, Weijun Wang, Encouse B. Golden, Simmy Thomas, Walavan Sivakumar, Florence M. Hofman, Stan G. Louie, Axel H. Schönthal	2011	84
19	Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo Molecular Cancer ·Peter Pyrko, Nathaniel Soriano, Adel Kardosh, Yen‐Ting Liu, Jasim Uddin, Nicos A. Petasis, Florence M. Hofman, Ching-Shih Chen, Thomas C. Chen, Axel H. Schönthal	2006	78
20	Perillyl Alcohol for the Treatment of Temozolomide-Resistant Gliomas Molecular Cancer Therapeutics ·Hee‐Yeon Cho, Weijun Wang, Niyati Jhaveri, Shering Torres, Joshua Tseng, Michelle N. Leong, David Jungpa Lee, Amir Goldkorn, Tong Xu, Nicos A. Petasis, Stan G. Louie, Axel H. Schönthal, Florence M. Hofman, Thomas C. Chen	2012	76

About Thomas C. Chen

Thomas C. Chen is a scholar working on Molecular Biology, Genetics, Epidemiology, Oncology and Pulmonary and Respiratory Medicine, having authored 176 papers that have together received 5.9k indexed citations. Recurring topics across this work include Glioma Diagnosis and Treatment (48 papers), Brain Metastases and Treatment (21 papers), Meningioma and schwannoma management (16 papers), Autophagy in Disease and Therapy (15 papers), Endoplasmic Reticulum Stress and Disease (13 papers), Immunotherapy and Immune Responses (12 papers), Cell Adhesion Molecules Research (11 papers) and Spine and Intervertebral Disc Pathology (11 papers). The work is most often cited by research in Genetics (887 citations), Cell Biology (861 citations), Physiology (225 citations), Cancer Research (665 citations) and Pathology and Forensic Medicine (646 citations). Thomas C. Chen has collaborated with scholars based in United States, China and Taiwan. Frequent co-authors include Axel H. Schönthal, Florence M. Hofman, Stan G. Louie, Weijun Wang, Peter Pyrko, Nicos A. Petasis, Encouse B. Golden, Adel Kardosh, Martin H. Weiss and William T. Couldwell. Their work appears in journals such as Neurosurgical FOCUS, Journal of neurosurgery, Neurosurgery, Cancer Letters and Molecular Cancer Therapeutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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