Martin Chalfie

24.1k citations

119 papers · 17.6k indexed · 13 hit papers · h-index 57

Molecular Biology top 0.2%
Aging top 0.01%
Endocrine and Autonomic Systems top 0.05%
Cellular and Molecular Neuroscience top 0.5%
Physiology top 0.5%

Co-authors: Yuan Tu William W. Ward Ghia Euskirchen Douglas C. Prasher John Sulston Monica Driscoll Jeffrey C. Way J. Nichol Thomson
Topics: Genetics, Aging, and Longevity in Model Organisms (90 papers)Circadian rhythm and melatonin (33 papers)Spaceflight effects on biology (21 papers)
Cited by: Aging Endocrine and Autonomic Systems Biophysics
Journals: Nature Science Cell
Partner nations: United States United Kingdom Chile

In The Last Decade

Martin Chalfie

118 papers receiving 17.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Green Fluorescent Protein as a Marker for Gene Expression

1994 5.1k citations Martin Chalfie et al. profile →
The neural circuit for touch sensitivity in Caenorhabditis elegans

1985 821 citations Martin Chalfie et al. Journal of Neuroscience profile →
Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans

1981 583 citations Martin Chalfie et al. profile →
mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegans

1988 496 citations Martin Chalfie et al. Cell profile →
Serotonin and Octopamine in the Nematode Caenorhabditis elegans

1982 480 citations H. Robert Horvitz, Martin Chalfie et al. profile →
The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration

1991 459 citations Martin Chalfie et al. profile →
Mutations that lead to reiterations in the cell lineages of C. elegans

1981 408 citations Martin Chalfie Cell profile →
The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals

2004 392 citations Robert O’Hagan, Martin Chalfie et al. Nature Neuroscience profile →
Neurosensory mechanotransduction

2008 301 citations Martin Chalfie profile →
Genetic Control of Differentiation of the Caenorhabditis elegans Touch Receptor Neurons

1989 284 citations Martin Chalfie et al. profile →
The mec-3 gene of Caenorhabditis elegans requires its own product for maintained expression and is expressed in three neuronal cell types.

1989 270 citations Martin Chalfie et al. profile →
The identification and suppression of inherited neurodegeneration in Caenorhabditis elegans

1990 249 citations Martin Chalfie et al. profile →
mec-7 is a beta-tubulin gene required for the production of 15-protofilament microtubules in Caenorhabditis elegans.

1989 247 citations Martin Chalfie et al. profile →

Peers

Countries citing papers authored by Martin Chalfie

Since Specialization

Citations

This map shows the geographic impact of Martin Chalfie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Martin Chalfie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Martin Chalfie more than expected).

Fields of papers citing papers by Martin Chalfie

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Martin Chalfie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Martin Chalfie. The network helps show where Martin Chalfie may publish in the future.

Co-authorship network of co-authors of Martin Chalfie

This figure shows the co-authorship network connecting the top 25 collaborators of Martin Chalfie. A scholar is included among the top collaborators of Martin Chalfie based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Martin Chalfie. Martin Chalfie is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism 2025 ·Proceedings of the National Academy of Sciences ·Victor Ambros,Martin Chalfie,(unknown),Andrew Fire,David H. Hall,H. Robert Horvitz,Craig C. Mello,Gary Ruvkun,Nathan E. Schroeder,Paul W. Sternberg,Ann E. Rougvie	1
2	Opposing effects of an F-box protein and the HSP90 chaperone network on microtubule stability and neurite growth in Caenorhabditis elegans 2020 ·Development ·Chaogu Zheng,(unknown),(unknown),(unknown),Ken C. Q. Nguyen,David H. Hall,Martin Chalfie	11
3	Epistatic, synthetic, and balancing interactions among tubulin missense mutations affecting neurite growth inCaenorhabditis elegans 2020 ·Molecular Biology of the Cell ·(unknown),(unknown),(unknown),(unknown),Martin Chalfie,Chaogu Zheng	11
4	Inhibition of cell fate repressors secures the differentiation of the touch receptor neurons of Caenorhabditis elegans 2018 ·Development ·Chaogu Zheng,(unknown),Brian L. Trippe,Ji Wu,Martin Chalfie	7
5	GEFs and Rac GTPases control directional specificity of neurite extension along the anterior–posterior axis 2016 ·Proceedings of the National Academy of Sciences ·Chaogu Zheng,Margarete Díaz-Cuadros,Martin Chalfie	15
6	Caenorhabditis elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins 2016 ·Molecular Biology of the Cell ·Yushu Chen,Shashank Bharill,Zeynep F. Altun,Robert O’Hagan,Brian Coblitz,Ehud Y. Isacoff,Martin Chalfie	23
7	Caenorhabditis elegans aristaless/Arx gene alr-1 restricts variable gene expression 2011 ·Proceedings of the National Academy of Sciences ·Irini Topalidou,Alexander van Oudenaarden,Martin Chalfie	38
8	Microtubule depolymerization in Caenorhabditis elegans touch receptor neurons reduces gene expression through a p38 MAPK pathway 2011 ·Proceedings of the National Academy of Sciences ·(unknown),John Kratz,(unknown),Marie‐Aline Charles,Ken C. Q. Nguyen,Martin Chalfie	68
9	The DEG/ENaC Protein MEC-10 Regulates the Transduction Channel Complex inCaenorhabditis elegansTouch Receptor Neurons 2011 ·Journal of Neuroscience ·(unknown),Robert O’Hagan,Yushu Chen,Miriam B. Goodman,Martin Chalfie	68
10	Enhanced neuronal RNAi in C. elegans using SID-1 2010 ·Nature Methods ·Andrea Calixto,(unknown),Irini Topalidou,Xiaoyin Chen,Martin Chalfie	286
11	GFP: Ein Protein bringt Licht ins Dunkel (Nobel‐Vortrag) 2009 ·Angewandte Chemie ·Martin Chalfie	11
12	Targeted cell killing by reconstituted caspases 2007 ·Proceedings of the National Academy of Sciences ·(unknown),Martin Chalfie	126
13	Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels 2006 ·Proceedings of the National Academy of Sciences ·Tobias B. Huber,Bernhard Schermer,Roman Ulrich Müller,Martin Höhne,Malte P. Bartram,Andrea Calixto,Henning Hagmann,Christian Reinhardt,(unknown),Karl Kunzelmann,Elena A. Shirokova,Dietmar Krautwurst,Christian Harteneck,Matias Simons,Hermann Pavenstädt,Dontscho Kerjaschki,Christoph Thiele,Gerd Walz,Martin Chalfie,Thomas Benzing	236
14	Extracellular Proteins Organize the Mechanosensory Channel Complex in C. elegans Touch Receptor Neurons 2004 ·Neuron ·(unknown),Guoqiang Gu,Erika Hartwieg,Martin Chalfie	102
15	MEC-2 Is Recruited to the Putative Mechanosensory Complex in C. elegans Touch Receptor Neurons through Its Stomatin-like Domain 2004 ·Current Biology ·Shifang Zhang,(unknown),(unknown),Guy A. Caldwell,Chengyuan Yao,Martin Chalfie	87
16	The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signalsbreakdown → 2004 ·Nature Neuroscience ·Robert O’Hagan,Martin Chalfie,Miriam B. Goodman	392
17	Combinatorial Marking of Cells and Organelles with Reconstituted Fluorescent Proteins 2004 ·Cell ·Shifang Zhang,Marie‐Aline Charles,Martin Chalfie	119
18	Nucleotide Binding by the MDM2 RING Domain Facilitates Arf-Independent MDM2 Nucleolar Localization 2003 ·Molecular Cell ·Masha V. Poyurovsky,Xavier Jacq,Marie‐Aline Charles,Orit Karni-Schmidt,Peter J. Parker,Martin Chalfie,James L. Manley,Carol Prives	51
19	Caenorhabditis elegans development 1989 ·Current Opinion in Cell Biology ·Martin Chalfie	16
20	11 The Nervous System 1988 ·Cold Spring Harbor Monograph Archive ·Martin Chalfie,John G. White	2

About Martin Chalfie

Martin Chalfie is a scholar working on Aging, Endocrine and Autonomic Systems and Physiology, having authored 119 papers that have together received 17.6k indexed citations. Recurring topics across this work include Genetics, Aging, and Longevity in Model Organisms (90 papers), Circadian rhythm and melatonin (33 papers) and Spaceflight effects on biology (21 papers). The work is most often cited by research in Aging (6.8k citations), Endocrine and Autonomic Systems (3.3k citations) and Biophysics (1.8k citations). Martin Chalfie has collaborated with scholars based in United States, United Kingdom and Chile. Frequent co-authors include Yuan Tu, William W. Ward, Ghia Euskirchen, Douglas C. Prasher, John Sulston, Monica Driscoll, Jeffrey C. Way, J. Nichol Thomson, Robert O’Hagan and Mingxia Huang. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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