Sylva L. U. Schwager

2.8k total citations · 1 hit paper
45 papers, 2.3k citations indexed

About

Sylva L. U. Schwager is a scholar working on Molecular Biology, Oncology and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Sylva L. U. Schwager has authored 45 papers receiving a total of 2.3k indexed citations (citations by other indexed papers that have themselves been cited), including 38 papers in Molecular Biology, 17 papers in Oncology and 16 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Sylva L. U. Schwager's work include Peptidase Inhibition and Analysis (17 papers), Renin-Angiotensin System Studies (15 papers) and Chemical Synthesis and Analysis (12 papers). Sylva L. U. Schwager is often cited by papers focused on Peptidase Inhibition and Analysis (17 papers), Renin-Angiotensin System Studies (15 papers) and Chemical Synthesis and Analysis (12 papers). Sylva L. U. Schwager collaborates with scholars based in South Africa, United Kingdom and United States. Sylva L. U. Schwager's co-authors include Edward D. Sturrock, K. Ravi Acharya, R. Natesh, Mario R. Ehlers, Hazel R. Evans, Geoffrey Masuyer, Hazel Corradi, Adriana K. Carmona, R. Elwyn Isaac and Wolf F. Brandt and has published in prestigious journals such as Nature, Journal of Biological Chemistry and PLoS ONE.

In The Last Decade

Sylva L. U. Schwager

44 papers receiving 2.3k citations

Hit Papers

1 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Crystal structure of the human angiotensin-converting enzyme–lisinopril complex

2003 712 citations R. Natesh, Sylva L. U. Schwager et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sylva L. U. Schwager South Africa	24	1.6k	572	465	372	337	45	2.3k
R. Natesh United Kingdom	12	1.1k 0.7×	220 0.4×	266 0.6×	178 0.5×	242 0.7×	21	1.5k
Emily F. Sabo United States	19	2.1k 1.3×	287 0.5×	187 0.4×	394 1.1×	541 1.6×	32	2.9k
G. Jayarama Bhat United States	27	1.2k 0.8×	300 0.5×	39 0.1×	406 1.1×	41 0.1×	53	2.1k
Otto D. Hensens United States	32	2.5k 1.5×	94 0.2×	228 0.5×	566 1.5×	80 0.2×	71	4.7k
Ian P. Street Australia	31	1.9k 1.2×	59 0.1×	82 0.2×	366 1.0×	44 0.1×	57	3.0k
Adam Yasgar United States	25	1.4k 0.9×	67 0.1×	540 1.2×	286 0.8×	21 0.1×	51	2.4k
Mark R. Player United States	28	1.0k 0.6×	102 0.2×	129 0.3×	304 0.8×	15 0.0×	97	2.5k
Xing Du China	22	1.5k 0.9×	26 0.0×	301 0.6×	278 0.7×	29 0.1×	47	2.7k
E H Ulm United States	23	1.1k 0.7×	154 0.3×	160 0.3×	220 0.6×	12 0.0×	47	1.6k
Stephen J. Ballaron United States	20	925 0.6×	83 0.1×	91 0.2×	212 0.6×	17 0.1×	26	1.8k

Countries citing papers authored by Sylva L. U. Schwager

Since Specialization

Citations

This map shows the geographic impact of Sylva L. U. Schwager's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sylva L. U. Schwager with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sylva L. U. Schwager more than expected).

Fields of papers citing papers by Sylva L. U. Schwager

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sylva L. U. Schwager. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sylva L. U. Schwager. The network helps show where Sylva L. U. Schwager may publish in the future.

Co-authorship network of co-authors of Sylva L. U. Schwager

This figure shows the co-authorship network connecting the top 25 collaborators of Sylva L. U. Schwager. A scholar is included among the top collaborators of Sylva L. U. Schwager based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sylva L. U. Schwager. Sylva L. U. Schwager is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Cozier, Gyles E., Charles J. Eyermann, Gregory S. Basarab, et al.. (2025). Design of Novel Mercapto-3-phenylpropanoyl Dipeptides as Dual Angiotensin-Converting Enzyme C–Domain-Selective/Neprilysin Inhibitors. Journal of Medicinal Chemistry. 68(7). 7720–7736.

Cozier, Gyles E., et al.. (2022). Structural basis for the inhibition of human angiotensin‐1 converting enzyme by fosinoprilat. FEBS Journal. 289(21). 6659–6671. 3 indexed citations

Arendse, Lauren B., Gyles E. Cozier, Charles J. Eyermann, et al.. (2022). Probing the Requirements for Dual Angiotensin-Converting Enzyme C-Domain Selective/Neprilysin Inhibition. Journal of Medicinal Chemistry. 65(4). 3371–3387. 9 indexed citations

Sturrock, Edward D., Gyles E. Cozier, Sylva L. U. Schwager, et al.. (2019). Structural basis for the C-domain-selective angiotensin-converting enzyme inhibition by bradykinin-potentiating peptide b (BPPb). Biochemical Journal. 476(10). 1553–1570. 18 indexed citations

Cozier, Gyles E., et al.. (2018). Investigation into the Mechanism of Homo- and Heterodimerization of Angiotensin-Converting Enzyme. Molecular Pharmacology. 93(4). 344–354. 5 indexed citations

Jones, Erika, Maia Lesosky, Sandra Castel, et al.. (2017). Therapeutic drug monitoring of amlodipine and the Z-FHL/HHL ratio: Adherence tools in patients referred for apparent treatment-resistant hypertension. South African Medical Journal. 107(10). 887–887. 7 indexed citations

Masuyer, Geoffrey, et al.. (2016). Kinetic and structural characterization of amyloid‐β peptide hydrolysis by human angiotensin‐1‐converting enzyme. FEBS Journal. 283(6). 1060–1076. 18 indexed citations

Akif, Mohd, Sylva L. U. Schwager, Geoffrey Masuyer, et al.. (2014). Interkingdom Pharmacology of Angiotensin-I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes. ACS Medicinal Chemistry Letters. 5(4). 346–351. 28 indexed citations

Danilov, Sergei M., Michael S. Wade, Sylva L. U. Schwager, et al.. (2014). A Novel Angiotensin I-Converting Enzyme Mutation (S333W) Impairs N-Domain Enzymatic Cleavage of the Anti-Fibrotic Peptide, AcSDKP. PLoS ONE. 9(2). e88001–e88001. 21 indexed citations

10.

Masuyer, Geoffrey, Sylva L. U. Schwager, Edward D. Sturrock, R. Elwyn Isaac, & K. Ravi Acharya. (2012). Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides. Scientific Reports. 2(1). 717–717. 131 indexed citations

11.

Akif, Mohd, Geoffrey Masuyer, Sylva L. U. Schwager, et al.. (2011). Structural characterization of angiotensin I‐converting enzyme in complex with a selenium analogue of captopril. FEBS Journal. 278(19). 3644–3650. 26 indexed citations

12.

Anthony, Colin, Hazel Corradi, Sylva L. U. Schwager, et al.. (2010). The N Domain of Human Angiotensin-I-converting Enzyme. Journal of Biological Chemistry. 285(46). 35685–35693. 76 indexed citations

13.

Corradi, Hazel, Sylva L. U. Schwager, Aloysius T. Nchinda, Edward D. Sturrock, & K. Ravi Acharya. (2006). Crystal Structure of the N Domain of Human Somatic Angiotensin I-converting Enzyme Provides a Structural Basis for Domain-specific Inhibitor Design. Journal of Molecular Biology. 357(3). 964–974. 133 indexed citations

14.

Carmona, Adriana K., Sylva L. U. Schwager, María A. Juliano, Luiz Juliano, & Edward D. Sturrock. (2006). A continuous fluorescence resonance energy transfer angiotensin I-converting enzyme assay. Nature Protocols. 1(4). 1971–1976. 86 indexed citations

15.

Natesh, R., Sylva L. U. Schwager, Hazel R. Evans, Edward D. Sturrock, & K. Ravi Acharya. (2004). Structural Details on the Binding of Antihypertensive Drugs Captopril and Enalaprilat to Human Testicular Angiotensin I-Converting Enzyme ^,. Biochemistry. 43(27). 8718–8724. 234 indexed citations

16.

Parkin, Edward T., Thomas P. Condon, Sylva L. U. Schwager, et al.. (2004). The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein. European Journal of Biochemistry. 271(12). 2539–2547. 72 indexed citations

17.

Natesh, R., Sylva L. U. Schwager, Edward D. Sturrock, & K. Ravi Acharya. (2003). Crystal structure of the human angiotensin-converting enzyme–lisinopril complex. Nature. 421(6922). 551–554. 712 indexed citations breakdown →

18.

Chubb, Anthony J., et al.. (2001). Roles of the juxtamembrane and extracellular domains of angiotensin-converting enzyme in ectodomain shedding. Biochemical Journal. 358(1). 185–185. 33 indexed citations

19.

Schwager, Sylva L. U., Anthony J. Chubb, Renate R. Scholle, et al.. (1999). Modulation of Juxtamembrane Cleavage (“Shedding”) of Angiotensin-Converting Enzyme by Stalk Glycosylation: Evidence for an Alternative Shedding Protease. Biochemistry. 38(32). 10388–10397. 29 indexed citations

20.

Schwager, Sylva L. U., Anthony J. Chubb, Renate R. Scholle, et al.. (1998). Phorbol Ester-Induced Juxtamembrane Cleavage of Angiotensin-Converting Enzyme Is Not Inhibited by a Stalk Containing Intrachain Disulfides. Biochemistry. 37(44). 15449–15456. 14 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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