Steven Fletcher

4.0k citations

110 papers · 3.3k indexed · h-index 35

Co-authors: Patrick T. Gunning Andrew D. Hamilton Edward V. Prochownik Jeremy L. Yap James Turkson Lijia Chen Maryanna E. Lanning Jay Chauhan
Topics: Chemical Synthesis and Analysis (20 papers)Protein Degradation and Inhibitors (17 papers)Cell death mechanisms and regulation (14 papers)
Cited by: Organic Chemistry Oncology Toxicology
Journals: Angewandte Chemie International Edition Blood Biomaterials
Partner nations: United States Canada United Kingdom

In The Last Decade

Steven Fletcher

105 papers receiving 3.3k citations

Peers

Countries citing papers authored by Steven Fletcher

Since Specialization

Citations

This map shows the geographic impact of Steven Fletcher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven Fletcher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven Fletcher more than expected).

Fields of papers citing papers by Steven Fletcher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven Fletcher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven Fletcher. The network helps show where Steven Fletcher may publish in the future.

Co-authorship network of co-authors of Steven Fletcher

This figure shows the co-authorship network connecting the top 25 collaborators of Steven Fletcher. A scholar is included among the top collaborators of Steven Fletcher based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Steven Fletcher. Steven Fletcher is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The polypharmacy combination of the BCL-2 inhibitor venetoclax (VEN) and the FLT3 inhibitor gilteritinib (GIL) is more active in acute myeloid leukemia cells than novel polypharmacologic BCL-2/FLT3 VEN–GIL hybrid single-molecule inhibitors 2024 ·European Journal of Medicinal Chemistry ·(unknown),(unknown),(unknown),Minjung Kim,(unknown),Curt I. Civin,Steven Fletcher	4
2	First-in-class mitogen-activated protein kinase (MAPK) p38α: MAPK-activated protein kinase 2 dual signal modulator with anti-inflammatory and endothelial-stabilizing properties 2024 ·Journal of Pharmacology and Experimental Therapeutics ·Mohan E. Tulapurkar,Kari Ann Shirey,(unknown),Wendy Luo,(unknown),Adam Galan,(unknown),(unknown),Kiruphagaran Thangaraju,(unknown),Daniel R. Lewis,William A. Murphy,Steven Fletcher,Alexander D. MacKerell,Stefanie N. Vogel,Paul R. Shapiro,Jeffrey D. Hasday	2
3	Multimodal nanoparticle‐containing modified suberoylanilide hydroxamic acid polymer conjugates to mitigate immune dysfunction in severe inflammation 2023 ·Bioengineering & Translational Medicine ·(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Steven Fletcher,Ryan M. Pearson	6
4	VLA4-Targeted Nanoparticles Hijack Cell Adhesion–Mediated Drug Resistance to Target Refractory Myeloma Cells and Prolong Survival 2020 ·Clinical Cancer Research ·Francesca Fontana,Michael J. Scott,John S. Allen,Xiaoxia Yang,Grace Cui,Dipanjan Pan,(unknown),Mark A. Fiala,Julie O’Neal,(unknown),Julie Ritchey,Michael P. Rettig,(unknown),Steven Fletcher,Ravi Vij,John F. DiPersio,Gregory M. Lanza	19
5	Nanotherapy delivery of c-myc inhibitor targets Protumor Macrophages and preserves Antitumor Macrophages in Breast Cancer 2020 ·Theranostics ·Alison K. Esser,Michael H. Ross,Francesca Fontana,Xinming Su,(unknown),(unknown),Yalin Xu,Jingyu Xiang,Anne H. Schmieder,Xiaoxia Yang,Grace Cui,Michael J. Scott,Samuel Achilefu,Jay Chauhan,Steven Fletcher,Gregory M. Lanza,Katherine N. Weilbaecher	31
6	Dual Farnesyl and Geranylgeranyl Transferase Inhibitor Thwarts Mutant KRAS-Driven Patient-Derived Pancreatic Tumors 2019 ·Clinical Cancer Research ·Aslamuzzaman Kazi,Shengyan Xiang,Hua Yang,Liwei Chen,Perry Kennedy,Muhammad Ayaz,Steven Fletcher,Christopher T. Cummings,Harshani R. Lawrence,Francisca Beato,Ya’an Kang,Michael P. Kim,Andrea E. Delitto,Patrick W. Underwood,Jason B. Fleming,José G. Treviño,Andrew D. Hamilton,Saı̈d M. Sebti	53
7	Optimization of a small-molecule Lipid II binder 2019 ·Bioorganic & Medicinal Chemistry Letters ·Jay Chauhan,Steven M. Kwasny,Steven Fletcher,(unknown),(unknown)	0
8	Discovery and lead identification of quinazoline-based BRD4 inhibitors 2018 ·Bioorganic & Medicinal Chemistry Letters ·Shyh‐Ming Yang,Daniel J. Urban,Makoto Yoshioka,Jeffrey Strovel,Steven Fletcher,Amy Q. Wang,Xin Xu,Pranav Shah,Xin Hu,Matthew D. Hall,Ajit Jadhav,David J. Maloney	13
9	Discovery of Mcl-1 inhibitors based on a thiazolidine-2,4-dione scaffold 2017 ·Bioorganic & Medicinal Chemistry Letters ·E. E. Whiting,Mithun Raje,Jay Chauhan,Paul T. Wilder,(unknown),(unknown),(unknown),(unknown),(unknown),Steven Fletcher	15
10	A quantitative, surface plasmon resonance-based approach to evaluating DNA binding by the c-Myc oncoprotein and its disruption by small molecule inhibitors 2015 ·Journal of Biological Methods ·Huabo Wang,(unknown),Steven Fletcher,Edward V. Prochownik	17
11	Small-molecule inhibitors of the Myc oncoprotein 2014 ·Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms ·Steven Fletcher,Edward V. Prochownik	120
12	The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibition 2012 ·BMC Cancer ·(unknown),Daniel C. Jupiter,Steven Fletcher,Jeremy L. Yap,Arun Rai,Richard P. Tobin,Weihua Jiang,(unknown),(unknown),W. Roy Smythe,Xiaobo Cao	70
13	Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitors 2012 ·Organic & Biomolecular Chemistry ·Jeremy L. Yap,Xiaobo Cao,Kenno Vanommeslaeghe,Kwan‐Young Jung,(unknown),Paul T. Wilder,Anjan Nan,Alexander D. MacKerell,W. Roy Smythe,Steven Fletcher	54
14	An activatable multimodal/multifunctional nanoprobe for direct imaging of intracellular drug delivery 2011 ·Biomaterials ·Rajendra Narayan Mitra,(unknown),Xiaolei Zhang,(unknown),Niclas E. Bengtsson,Steven Fletcher,Brent D. G. Page,James Turkson,Andre J. Gesquiere,Patrick T. Gunning,Glenn A. Walter,Swadeshmukul Santra	48
15	Disruption of Transcriptionally Active Stat3 Dimers with Non‐phosphorylated, Salicylic Acid‐Based Small Molecules: Potent in vitro and Tumor Cell Activities 2009 ·ChemBioChem ·Steven Fletcher,(unknown),Xiaolei Zhang,Peibin Yue,Brent D. G. Page,Sumaiya Sharmeen,Vijay Shahani,Wei Zhao,Aaron D. Schimmer,James Turkson,Patrick T. Gunning	70
16	A Photostable, pH-Invariant Fluorescein Derivative for Single-Molecule Microscopy 2009 ·Journal of Fluorescence ·Baoxu Liu,Steven Fletcher,(unknown),Patrick T. Gunning,Claudiu C. Gradinaru	30
17	Molecular Approaches towards the Inhibition of the Signal Transducer and Activator of Transcription 3 (Stat3) Protein 2008 ·ChemMedChem ·Steven Fletcher,James Turkson,Patrick T. Gunning	88
18	Protein-Protein Interaction Inhibitors: Small Molecules from Screening Techniques 2007 ·Current Topics in Medicinal Chemistry ·Steven Fletcher,(unknown)	54
19	Recognition of solvent exposed protein surfaces using anthracene derived receptors 2006 ·Organic & Biomolecular Chemistry ·Andrew J. Wilson,Jason Hong,Steven Fletcher,Andrew D. Hamilton	31
20	Protein surface recognition and proteomimetics: mimics of protein surface structure and function 2005 ·Current Opinion in Chemical Biology ·Steven Fletcher,Andrew D. Hamilton	103

About Steven Fletcher

Steven Fletcher is a scholar working on Toxicology, Molecular Biology and Organic Chemistry, having authored 110 papers that have together received 3.3k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (20 papers), Protein Degradation and Inhibitors (17 papers) and Cell death mechanisms and regulation (14 papers). The work is most often cited by research in Organic Chemistry (1.1k citations), Oncology (980 citations) and Toxicology (120 citations). Steven Fletcher has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Patrick T. Gunning, Andrew D. Hamilton, Edward V. Prochownik, Jeremy L. Yap, James Turkson, Lijia Chen, Maryanna E. Lanning, Jay Chauhan, Peibin Yue and Xiaolei Zhang. Their work appears in journals such as Angewandte Chemie International Edition, Blood and Biomaterials.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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