Stefano Sainas

914 total citations
23 papers, 440 citations indexed

About

Stefano Sainas is a scholar working on Molecular Biology, Infectious Diseases and Organic Chemistry. According to data from OpenAlex, Stefano Sainas has authored 23 papers receiving a total of 440 indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Biology, 11 papers in Infectious Diseases and 5 papers in Organic Chemistry. Recurrent topics in Stefano Sainas's work include Biochemical and Molecular Research (14 papers), HIV/AIDS drug development and treatment (10 papers) and Click Chemistry and Applications (3 papers). Stefano Sainas is often cited by papers focused on Biochemical and Molecular Research (14 papers), HIV/AIDS drug development and treatment (10 papers) and Click Chemistry and Applications (3 papers). Stefano Sainas collaborates with scholars based in Italy, United States and Sweden. Stefano Sainas's co-authors include Donatella Boschi, Marco L. Lolli, Agnese Chiara Pippione, Marta Giorgis, Franco Dosio, Salam Al‐Karadaghi, Anna Luganini, Giorgio Gribaudo, Marco Piccinini and Elisa Lupino and has published in prestigious journals such as FEBS Letters, Journal of Medicinal Chemistry and Molecules.

In The Last Decade

Stefano Sainas

23 papers receiving 437 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Stefano Sainas Italy 12 266 112 98 79 47 23 440
Lisa Gruber Germany 17 319 1.2× 50 0.4× 72 0.7× 93 1.2× 74 1.6× 21 677
Chad E. Schroeder United States 11 241 0.9× 81 0.7× 98 1.0× 69 0.9× 21 0.4× 20 538
Ganeko Bernardo‐Seisdedos Spain 14 497 1.9× 95 0.8× 63 0.6× 53 0.7× 11 0.2× 35 654
Xiaohe Guo China 12 223 0.8× 86 0.8× 90 0.9× 47 0.6× 61 1.3× 32 445
Anette Klinger Germany 13 217 0.8× 56 0.5× 67 0.7× 43 0.5× 24 0.5× 20 362
Michael A. Hast United States 12 479 1.8× 81 0.7× 114 1.2× 72 0.9× 36 0.8× 20 668
Adrien Herlédan France 12 260 1.0× 45 0.4× 50 0.5× 37 0.5× 16 0.3× 21 441
Weimei Sun United States 14 493 1.9× 36 0.3× 43 0.4× 31 0.4× 18 0.4× 24 647
Mariantonietta Forgione Italy 10 326 1.2× 37 0.3× 81 0.8× 162 2.1× 25 0.5× 10 648
A.E. Oberholzer Switzerland 12 488 1.8× 27 0.2× 92 0.9× 24 0.3× 30 0.6× 12 685

Countries citing papers authored by Stefano Sainas

Since Specialization
Citations

This map shows the geographic impact of Stefano Sainas's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stefano Sainas with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stefano Sainas more than expected).

Fields of papers citing papers by Stefano Sainas

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stefano Sainas. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stefano Sainas. The network helps show where Stefano Sainas may publish in the future.

Co-authorship network of co-authors of Stefano Sainas

This figure shows the co-authorship network connecting the top 25 collaborators of Stefano Sainas. A scholar is included among the top collaborators of Stefano Sainas based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stefano Sainas. Stefano Sainas is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Sainas, Stefano, Elena Martino, Claudio Garino, et al.. (2025). Fluorescent Isostere (Fluostere) of the Carboxylate: Design of hDHODH Fluorescent Inhibitors as Proof of Concept. Journal of Medicinal Chemistry. 68(13). 13562–13590. 1 indexed citations
2.
Poli, Giulio, Stefano Sainas, Menico Rizzi, et al.. (2024). An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent. Acta Crystallographica Section D Structural Biology. 80(6). 386–396. 1 indexed citations
3.
Sainas, Stefano, et al.. (2024). Radiosynthesis of [ 18 F]brequinar for in vivo PET imaging of hDHODH for potential studies of acute myeloid leukemia and cancers. RSC Medicinal Chemistry. 15(9). 3147–3161. 1 indexed citations
4.
Luganini, Anna, Maurizia Mello‐Grand, Stefano Sainas, et al.. (2023). Mechanisms of antiviral activity of the new hDHODH inhibitor MEDS433 against respiratory syncytial virus replication. Antiviral Research. 219. 105734–105734. 6 indexed citations
5.
Sainas, Stefano, Marco L. Lolli, Donatella Boschi, et al.. (2023). Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor. FEBS Letters. 597(16). 2119–2132. 4 indexed citations
6.
Luganini, Anna, et al.. (2022). The Novel hDHODH Inhibitor MEDS433 Prevents Influenza Virus Replication by Blocking Pyrimidine Biosynthesis. Viruses. 14(10). 2281–2281. 13 indexed citations
7.
Pippione, Agnese Chiara, Stefano Sainas, Barbara Rolando, et al.. (2022). New aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the hydroxytriazole scaffold. European Journal of Medicinal Chemistry. 237. 114366–114366. 11 indexed citations
8.
Calistri, Arianna, Anna Luganini, Barbara Mognetti, et al.. (2021). The New Generation hDHODH Inhibitor MEDS433 Hinders the In Vitro Replication of SARS-CoV-2 and Other Human Coronaviruses. Microorganisms. 9(8). 1731–1731. 25 indexed citations
9.
Pippione, Agnese Chiara, Matthew Boyko, Stefano Sainas, et al.. (2021). A New NF-κB Inhibitor, MEDS-23, Reduces the Severity of Adverse Post-Ischemic Stroke Outcomes in Rats. Brain Sciences. 12(1). 35–35. 10 indexed citations
10.
Luganini, Anna, Barbara Mognetti, Stefano Sainas, et al.. (2021). Effective deploying of a novel DHODH inhibitor against herpes simplex type 1 and type 2 replication. Antiviral Research. 189. 105057–105057. 25 indexed citations
11.
Boschi, Donatella, Agnese Chiara Pippione, Stefano Sainas, & Marco L. Lolli. (2019). Dihydroorotate dehydrogenase inhibitors in anti-infective drug research. European Journal of Medicinal Chemistry. 183. 111681–111681. 70 indexed citations
12.
Sainas, Stefano, Feng Yi, Anders A. Jensen, et al.. (2019). Use of the 4-Hydroxytriazole Moiety as a Bioisosteric Tool in the Development of Ionotropic Glutamate Receptor Ligands. Journal of Medicinal Chemistry. 62(9). 4467–4482. 14 indexed citations
13.
Sainas, Stefano, Franco Dosio, Donatella Boschi, & Marco L. Lolli. (2018). Chapter One - Targeting Human Onchocerciasis: Recent Advances Beyond Ivermectin. 1–38. 1 indexed citations
14.
Lolli, Marco L., Stefano Sainas, Agnese Chiara Pippione, et al.. (2018). Use of human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors in Autoimmune Diseases and New Perspectives in Cancer Therapy. Recent Patents on Anti-Cancer Drug Discovery. 13(1). 86–105. 59 indexed citations
15.
Sainas, Stefano, Agnese Chiara Pippione, Katia Martina, et al.. (2018). Regioselective N‐Alkylation of Ethyl 4‐Benzyloxy‐1,2,3‐triazolecarboxylate: A Useful Tool for the Synthesis of Carboxylic Acid Bioisosteres. Journal of Heterocyclic Chemistry. 56(2). 501–519. 11 indexed citations
16.
Pippione, Agnese Chiara, Stefano Sainas, Parveen Goyal, et al.. (2018). Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies. European Journal of Medicinal Chemistry. 163. 266–280. 33 indexed citations
17.
Pippione, Agnese Chiara, Stefano Sainas, Elisa Lupino, et al.. (2018). N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK. MedChemComm. 9(6). 963–968. 25 indexed citations
18.
Sainas, Stefano, Agnese Chiara Pippione, Donatella Boschi, et al.. (2018). DHODH inhibitors and leukemia: an emergent interest for new myeloid differentiation agents. Drugs of the Future. 43(11). 823–823. 6 indexed citations
19.
Pippione, Agnese Chiara, Stefano Sainas, Donatella Boschi, et al.. (2017). 4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade. MedChemComm. 8(9). 1850–1855. 15 indexed citations
20.
Sainas, Stefano, Agnese Chiara Pippione, Marta Giorgis, et al.. (2017). Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds. European Journal of Medicinal Chemistry. 129. 287–302. 44 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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