Spencer C. Liang

7.0k total citations · 4 hit papers
23 papers, 5.7k citations indexed

About

Spencer C. Liang is a scholar working on Immunology, Oncology and Molecular Biology. According to data from OpenAlex, Spencer C. Liang has authored 23 papers receiving a total of 5.7k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Immunology, 9 papers in Oncology and 4 papers in Molecular Biology. Recurrent topics in Spencer C. Liang's work include Immune Cell Function and Interaction (10 papers), Cancer Immunotherapy and Biomarkers (7 papers) and Psoriasis: Treatment and Pathogenesis (6 papers). Spencer C. Liang is often cited by papers focused on Immune Cell Function and Interaction (10 papers), Cancer Immunotherapy and Biomarkers (7 papers) and Psoriasis: Treatment and Pathogenesis (6 papers). Spencer C. Liang collaborates with scholars based in United States, United Kingdom and Italy. Spencer C. Liang's co-authors include Mary Collins, Kyriaki Dunussi‐Joannopoulos, Lynette A. Fouser, Gordon J. Freeman, Arlene H. Sharpe, Deborah Luxenberg, Xiangyang Tan, Yvette Latchman, Andi Qipo and Lee A. Albacker and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Clinical Investigation and The Journal of Experimental Medicine.

In The Last Decade

Spencer C. Liang

23 papers receiving 5.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

2006 1.9k citations Spencer C. Liang, Xiangyang Tan et al. The Journal of Experimental Medicine profile →
Tissue expression of PD-L1 mediates peripheral T cell tolerance

2006 1.0k citations Mary Keir, Spencer C. Liang et al. The Journal of Experimental Medicine profile →
PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

2004 521 citations Yvette Latchman, Spencer C. Liang et al. Proceedings of the National Academy of Sciences profile →
Regulation of PD‐1, PD‐L1, and PD‐L2 expression during normal and autoimmune responses

2003 518 citations Spencer C. Liang, Yvette Latchman et al. European Journal of Immunology profile →

Peers

Countries citing papers authored by Spencer C. Liang

Since Specialization

Citations

This map shows the geographic impact of Spencer C. Liang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Spencer C. Liang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Spencer C. Liang more than expected).

Fields of papers citing papers by Spencer C. Liang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Spencer C. Liang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Spencer C. Liang. The network helps show where Spencer C. Liang may publish in the future.

Co-authorship network of co-authors of Spencer C. Liang

This figure shows the co-authorship network connecting the top 25 collaborators of Spencer C. Liang. A scholar is included among the top collaborators of Spencer C. Liang based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Spencer C. Liang. Spencer C. Liang is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	AL008 Enhances Myeloid Antitumor Function by Inhibiting SIRPα Signaling and Activating Fc Receptors 2023 ·The Journal of Immunology ·(unknown), (unknown), Wei-Hsien Ho, Hua Long, (unknown), Arnon Rosenthal, Spencer C. Liang, Andrew Pincetic	5
2	Abstract 613: AL009 is a multi-Siglec inhibitor engineered to bind myeloid cells that enhances innate and adaptive immunity to cancer 2022 ·Cancer Research ·Sam C. Nalle, Helen Lam, (unknown), Hua Long, Spencer C. Liang, Arnon Rosenthal, (unknown)	1
3	875 AL009, a fusion protein and multi-Siglec inhibitor, repolarizes suppressive myeloid cells and potentiates anti-cancer effects 2021 ·Regular and Young Investigator Award Abstracts ·Sam C. Nalle, Helen Lam, Ling Yan Leung, Spencer C. Liang, Daniel Maslyar	1
4	COM902, a novel therapeutic antibody targeting TIGIT augments anti-tumor T cell function in combination with PVRIG or PD-1 pathway blockade 2021 ·Cancer Immunology Immunotherapy ·Kyle Hansen, Sandeep Kumar, Kathryn Logronio, Sarah Whelan, (unknown), Hsin‐Yuan Cheng, (unknown), (unknown), Patrick D. Wall, (unknown), Ling Leung, Eran Ophir, Zoya Alteber, Gady Cojocaru, (unknown), (unknown), Mark A. White, John Hunter, Spencer C. Liang, Maya F. Kotturi	29
5	PVRIG is a novel natural killer cell immune checkpoint receptor in acute myeloid leukemia 2020 ·Haematologica ·Jessica Li, Sarah Whelan, Maya F. Kotturi, Déborah Meyran, Criselle D’Souza, Kyle Hansen, Spencer C. Liang, John Hunter, Joseph A. Trapani, Paul J. Neeson	23
6	PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8+ T-cell Function 2019 ·Cancer Immunology Research ·Sarah Whelan, Eran Ophir, Maya F. Kotturi, Ofer Levy, Sudipto Ganguly, Ling Yan Leung, Ilan Vaknin, Sandeep Kumar, (unknown), Kyle Hansen, (unknown), (unknown), Abha Soni, Janis M. Taube, Amanda N. Fader, Tian‐Li Wang, Ie‐Ming Shih, Mark A. White, Drew M. Pardoll, Spencer C. Liang	125
7	Identification and characterization of distinct IL-17F expression patterns and signaling pathways in chronic lymphocytic leukemia and normal B lymphocytes 2015 ·Immunologic Research ·Barbara Sherry, Preetesh Jain, (unknown), Ling Leung, Steven L. Allen, Jonathan E. Kolitz, R. Kanti, (unknown), Spencer C. Liang, Rachael E. Hawtin, Nicholas Chiorazzi	13
8	Depletion of regulatory T cells by targeting folate receptor 4 enhances the potency of a GM-CSF-secreting tumor cell immunotherapy 2013 ·Clinical Immunology ·Spencer C. Liang, Марина Москаленко, Melinda Van Roey, Karin Jooss	21
9	Systems biology analysis of immune signaling in peripheral blood mononuclear cells (PBMC) of melanoma patients receiving ipilimumab; basis for clinical response biomarker identification 2013 ·Journal for ImmunoTherapy of Cancer ·(unknown), Ryan Alvarado, Andrew Conroy, Santosh Putta, Ester Simeone, Assunta Esposito, Mariaelena Capone, Gabriele Madonna, Antonio Maria Grimaldi, David B. Rosen, Spencer C. Liang, Alessandra Cesano, Paolo A. Ascierto, Rachael E. Hawtin	1
10	IL-22 Induces an Acute-Phase Response 2010 ·The Journal of Immunology ·Spencer C. Liang, Cheryl Nickerson‐Nutter, Debra D. Pittman, Yijun Carrier, Debra G. Goodwin, Kathleen Shields, (unknown), Scott H. Schelling, Quintus G. Medley, Hak‐Ling Ma, Mary Collins, Kyriaki Dunussi‐Joannopoulos, Lynette A. Fouser	135
11	IL-22 is required for Th17 cell–mediated pathology in a mouse model of psoriasis-like skin inflammation 2008 ·Journal of Clinical Investigation ·Hak‐Ling Ma, Spencer C. Liang, Jing Li, Lee Napierata, Tom Brown, Stephen Benoit, Mayra Senices, Davinder Gill, Kyriaki Dunussi‐Joannopoulos, Mary Collins, Cheryl Nickerson‐Nutter, Lynette A. Fouser, Deborah Young	461
12	IL-21 Has a Pathogenic Role in a Lupus-Prone Mouse Model and Its Blockade with IL-21R.Fc Reduces Disease Progression 2007 ·The Journal of Immunology ·(unknown), Thomas Brown, Spencer C. Liang, Deborah Young, Mary Collins, Kyri Dunussi‐Joannopoulos	238
13	An IL-17F/A Heterodimer Protein Is Produced by Mouse Th17 Cells and Induces Airway Neutrophil Recruitment 2007 ·The Journal of Immunology ·Spencer C. Liang, Andrew Long, Frann Bennett, Matthew J. Whitters, (unknown), Mary Collins, Samuel J. Goldman, Kyriaki Dunussi‐Joannopoulos, Cara Williams, Jill F. Wright, Lynette A. Fouser	288
14	53 IL-22, a TH17 and TH1 Cytokine, Regulates Local Tissue Inflammation in the Context of Autoimmune Disease 2007 ·Cytokine ·Martin Hegen, (unknown), Spencer C. Liang, Jing Li, Debra D. Pittman, (unknown), Stéphane Olland, Mary Collins, Kyriaki Dunussi‐Joannopoulos, Davinder Gill, Deborah Young, Cheryl Nickerson‐Nutter, Lynette A. Fouser	1
15	Tissue expression of PD-L1 mediates peripheral T cell tolerance breakdown → 2006 ·The Journal of Experimental Medicine ·Mary Keir, Spencer C. Liang, Indira Guleria, Yvette Latchman, Andi Qipo, Lee A. Albacker, Maria Koulmanda, Gordon J. Freeman, Mohamed H. Sayegh, Arlene H. Sharpe	1010
16	Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides breakdown → 2006 ·The Journal of Experimental Medicine ·Spencer C. Liang, Xiangyang Tan, Deborah Luxenberg, (unknown), Kyriaki Dunussi‐Joannopoulos, Mary Collins, Lynette A. Fouser	1859
17	PD‐L1 and PD‐L2 have distinct roles in regulating host immunity to cutaneous leishmaniasis 2005 ·European Journal of Immunology ·Spencer C. Liang, Rebecca J. Greenwald, Yvette Latchman, Lucia E. Rosas, Abhay R. Satoskar, Gordon J. Freeman, Arlene H. Sharpe	66
18	PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells breakdown → 2004 ·Proceedings of the National Academy of Sciences ·Yvette Latchman, Spencer C. Liang, Yin Wu, Tatyana Chernova, Raymond A. Sobel, Martina Klemm, Vijay K. Kuchroo, Gordon J. Freeman, Arlene H. Sharpe	521
19	Regulation of PD‐1, PD‐L1, and PD‐L2 expression during normal and autoimmune responses breakdown → 2003 ·European Journal of Immunology ·Spencer C. Liang, Yvette Latchman, Janet E. Buhlmann, Michal Tomczak, Bruce Horwitz, Gordon J. Freeman, Arlene H. Sharpe	518
20	Endothelial expression of PD‐L1 and PD‐L2 down‐regulates CD8⁺ T cell activation and cytolysis 2003 ·European Journal of Immunology ·Nancy Rodig, Timothy A. Ryan, Jessica A. Allen, Hong Pang, Nir Grabie, Tatyana Chernova, Edward Greenfield, Spencer C. Liang, Arlene H. Sharpe, Andrew H. Lichtman, Gordon J. Freeman	400

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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