Sjors H. W. Scheres

49.8k total citations · 29 hit papers
143 papers, 29.4k citations indexed

About

Sjors H. W. Scheres is a scholar working on Molecular Biology, Structural Biology and Physiology. According to data from OpenAlex, Sjors H. W. Scheres has authored 143 papers receiving a total of 29.4k indexed citations (citations by other indexed papers that have themselves been cited), including 99 papers in Molecular Biology, 49 papers in Structural Biology and 34 papers in Physiology. Recurrent topics in Sjors H. W. Scheres's work include Advanced Electron Microscopy Techniques and Applications (49 papers), Alzheimer's disease research and treatments (33 papers) and Electron and X-Ray Spectroscopy Techniques (32 papers). Sjors H. W. Scheres is often cited by papers focused on Advanced Electron Microscopy Techniques and Applications (49 papers), Alzheimer's disease research and treatments (33 papers) and Electron and X-Ray Spectroscopy Techniques (32 papers). Sjors H. W. Scheres collaborates with scholars based in United Kingdom, United States and Spain. Sjors H. W. Scheres's co-authors include Takanori Nakane, Jasenko Zivanov, Dari Kimanius, Xiao‐chen Bai, Erik Lindahl, Björn Forsberg, Michel Goedert, Wim J. H. Hagen, Benjamin Falcon and Alexey G. Murzin and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Sjors H. W. Scheres

141 papers receiving 29.2k citations

Hit Papers

RELION: Implementation of a Bayesian approach to cryo-EM ... 2006 2026 2012 2019 2012 2018 2017 2020 2016 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. RELION: Implementation of a Bayesian approach to cryo-EM structure determination
    2012 3.8k citations Sjors H. W. Scheres profile →
  2. New tools for automated high-resolution cryo-EM structure determination in RELION-3
    2018 3.3k citations Jasenko Zivanov, Takanori Nakane et al. eLife profile →
  3. Cryo-EM structures of tau filaments from Alzheimer’s disease
    2017 1.4k citations Benjamin Falcon, Shaoda He et al. Nature profile →
  4. Structures and distributions of SARS-CoV-2 spike proteins on intact virions
    2020 740 citations Zunlong Ke, Joaquı́n Otón et al. Nature profile →
  5. Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
    2016 728 citations Dari Kimanius, Sjors H. W. Scheres et al. eLife profile →
  6. High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy
    2013 695 citations Garib N. Murshudov, Sjors H. W. Scheres et al. profile →
  7. How cryo-EM is revolutionizing structural biology
    2014 620 citations Xiao‐chen Bai, Sjors H. W. Scheres et al. profile →
  8. A Bayesian View on Cryo-EM Structure Determination
    2011 612 citations Sjors H. W. Scheres profile →
  9. Structures of filaments from Pick’s disease reveal a novel tau protein fold
    2018 587 citations Benjamin Falcon, Wenjuan Zhang et al. Nature profile →
  10. New tools for automated cryo-EM single-particle analysis in RELION-4.0
    2021 563 citations Dari Kimanius, Takanori Nakane et al. profile →
  11. A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis
    2018 552 citations Jasenko Zivanov, Takanori Nakane et al. profile →
  12. Estimation of high-order aberrations and anisotropic magnification from cryo-EM data sets in RELION -3.1
    2020 514 citations Jasenko Zivanov, Takanori Nakane et al. profile →
  13. Structures of α-synuclein filaments from multiple system atrophy
    2020 510 citations Manuel Schweighauser, Yue‐De Yang et al. Nature profile →
  14. Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
    2019 492 citations Benjamin Falcon, Jasenko Zivanov et al. Nature profile →
  15. Sampling the conformational space of the catalytic subunit of human γ-secretase
    2015 469 citations Xiao‐chen Bai, Sjors H. W. Scheres et al. eLife profile →
  16. Structure of the Yeast Mitochondrial Large Ribosomal Subunit
    2014 460 citations Alexey Amunts, Alan Brown et al. Science profile →
  17. An atomic structure of human γ-secretase
    2015 406 citations Xiao‐chen Bai, Sjors H. W. Scheres et al. Nature profile →
  18. Processing of Structurally Heterogeneous Cryo-EM Data in RELION
    2016 394 citations Sjors H. W. Scheres profile →
  19. Novel tau filament fold in corticobasal degeneration
    2020 377 citations Wenjuan Zhang, Kathy L. Newell et al. Nature profile →
  20. Helical reconstruction in RELION
    2017 362 citations Shaoda He, Sjors H. W. Scheres profile →
  21. Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases
    2019 353 citations Wenjuan Zhang, Benjamin Falcon et al. eLife profile →
  22. Cryo-EM structures of amyloid-β 42 filaments from human brains
    2022 310 citations Wenjuan Zhang, Sofia Lövestam et al. profile →
  23. Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization
    2006 298 citations Sjors H. W. Scheres et al. Nature Methods profile →
  24. Structures of α-synuclein filaments from human brains with Lewy pathology
    2022 262 citations Yue‐De Yang, Manuel Schweighauser et al. Nature profile →
  25. Automated model building and protein identification in cryo-EM maps
    2024 231 citations Kiarash Jamali, Lukas Käll et al. Nature profile →
  26. A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0
    2022 170 citations Jasenko Zivanov, Joaquı́n Otón et al. eLife profile →
  27. Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids
    2023 121 citations Sjors H. W. Scheres, Benjamin Falcon et al. Nature profile →
  28. Data-driven regularization lowers the size barrier of cryo-EM structure determination
    2024 88 citations Dari Kimanius, Kiarash Jamali et al. Nature Methods profile →
  29. An image processing pipeline for electron cryo‐tomography in RELION ‐5
    2024 49 citations Alister Burt, Andriko von Kügelgen et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Sjors H. W. Scheres United Kingdom 72 19.8k 5.5k 5.3k 2.9k 2.4k 143 29.4k
Nikolaus Grigorieff United States 64 12.3k 0.6× 4.1k 0.8× 1.7k 0.3× 2.0k 0.7× 1.9k 0.8× 134 18.6k
Yifan Cheng United States 67 16.6k 0.8× 3.8k 0.7× 1.5k 0.3× 2.2k 0.8× 1.6k 0.6× 213 25.5k
David A. Agard United States 90 24.7k 1.2× 3.5k 0.6× 1.2k 0.2× 4.3k 1.5× 1.4k 0.6× 326 37.3k
Xiaowei Zhuang United States 95 21.2k 1.1× 5.3k 1.0× 1.3k 0.2× 2.7k 0.9× 301 0.1× 196 41.2k
Wah Chiu United States 88 16.8k 0.8× 5.3k 1.0× 596 0.1× 5.2k 1.8× 2.1k 0.9× 470 29.2k
Wolfgang Baumeister Germany 109 28.2k 1.4× 8.6k 1.6× 795 0.1× 4.4k 1.5× 3.8k 1.5× 481 38.8k
Thomas D. Goddard United States 13 30.2k 1.5× 1.6k 0.3× 1.5k 0.3× 4.6k 1.6× 464 0.2× 13 47.2k
Thomas Walz United States 87 17.5k 0.9× 1.2k 0.2× 3.1k 0.6× 1.4k 0.5× 476 0.2× 271 28.0k
Conrad C. Huang United States 31 31.3k 1.6× 1.5k 0.3× 1.5k 0.3× 4.9k 1.7× 443 0.2× 48 49.3k
Eric F. Pettersen United States 13 31.0k 1.6× 1.5k 0.3× 1.5k 0.3× 4.7k 1.6× 411 0.2× 15 48.2k

Countries citing papers authored by Sjors H. W. Scheres

Since Specialization
Citations

This map shows the geographic impact of Sjors H. W. Scheres's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sjors H. W. Scheres with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sjors H. W. Scheres more than expected).

Fields of papers citing papers by Sjors H. W. Scheres

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sjors H. W. Scheres. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sjors H. W. Scheres. The network helps show where Sjors H. W. Scheres may publish in the future.

Co-authorship network of co-authors of Sjors H. W. Scheres

This figure shows the co-authorship network connecting the top 25 collaborators of Sjors H. W. Scheres. A scholar is included among the top collaborators of Sjors H. W. Scheres based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sjors H. W. Scheres. Sjors H. W. Scheres is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Lövestam, Sofia, Michael A. Metrick, Thomas Löhr, et al.. (2025). Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau. FEBS Letters. 599(19). 2768–2778.
2.
Lövestam, Sofia, Lindsay Meyerdirk, Jacob A. McPhail, et al.. (2025). Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency. Nature Communications. 16(1). 9240–9240.
3.
Jamali, Kiarash, Lukas Käll, Rui Zhang, et al.. (2024). Automated model building and protein identification in cryo-EM maps. Nature. 628(8007). 450–457. 231 indexed citations breakdown →
4.
Schwab, Johannes, Dari Kimanius, Alister Burt, Tom Dendooven, & Sjors H. W. Scheres. (2024). DynaMight: estimating molecular motions with improved reconstruction from cryo-EM images. Nature Methods. 21(10). 1855–1862. 24 indexed citations
5.
Ghetti, Bernardino, Manuel Schweighauser, Max Jacobsen, et al.. (2024). TMEM106B amyloid filaments in the Biondi bodies of ependymal cells. Acta Neuropathologica. 148(1). 60–60. 2 indexed citations
6.
Qi, Chao, Bert M. Verheijen, Yasumasa Kokubo, et al.. (2023). Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proceedings of the National Academy of Sciences. 120(51). e2306767120–e2306767120. 22 indexed citations
7.
Yang, Yang, Holly J. Garringer, Yue‐De Yang, et al.. (2023). New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy. Acta Neuropathologica. 145(5). 561–572. 48 indexed citations
8.
Zivanov, Jasenko, Joaquı́n Otón, Zunlong Ke, et al.. (2022). A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0. eLife. 11. 170 indexed citations breakdown →
9.
Yang, Yue‐De, Alexey G. Murzin, Benjamin Falcon, et al.. (2021). Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607. Acta Neuropathologica. 141(5). 697–708. 127 indexed citations
10.
Hervás, Rubén, Michael Rau, Wenjuan Zhang, et al.. (2020). Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila. Science. 367(6483). 1230–1234. 133 indexed citations
11.
Scheres, Sjors H. W., Wenjuan Zhang, Benjamin Falcon, & Michel Goedert. (2020). Cryo-EM structures of tau filaments. Current Opinion in Structural Biology. 64. 17–25. 168 indexed citations
12.
Scheres, Sjors H. W.. (2020). Amyloid structure determination in RELION -3.1. Acta Crystallographica Section D Structural Biology. 76(2). 94–101. 162 indexed citations
13.
Ke, Zunlong, Joaquı́n Otón, Kun Qu, et al.. (2020). Structures and distributions of SARS-CoV-2 spike proteins on intact virions. Nature. 588(7838). 498–502. 740 indexed citations breakdown →
14.
Falcon, Benjamin, Jasenko Zivanov, Alexey G. Murzin, et al.. (2019). Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules. RePEc: Research Papers in Economics. 1 indexed citations
15.
Alvarez, Frances Joan D., Shaoda He, Juan R. Perilla, et al.. (2017). CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction. Science Advances. 3(9). e1701264–e1701264. 49 indexed citations
16.
Amunts, Alexey, et al.. (2015). The structure of the human mitochondrial ribosome. Science. 348(6230). 95–98. 386 indexed citations
17.
Amunts, Alexey, Alan Brown, Xiao‐chen Bai, et al.. (2014). Structure of the Yeast Mitochondrial Large Ribosomal Subunit. Science. 343(6178). 1485–1489. 460 indexed citations breakdown →
18.
Brown, Alan, Alexey Amunts, Xiao‐chen Bai, et al.. (2014). Structure of the large ribosomal subunit from human mitochondria. Science. 346(6210). 718–722. 242 indexed citations
19.
Wong, Wilson, Xiao‐chen Bai, Alan Brown, et al.. (2014). Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. eLife. 3. 242 indexed citations
20.
Fernandez, I.S., Xiao‐chen Bai, Tanweer Hussain, et al.. (2013). Molecular Architecture of a Eukaryotic Translational Initiation Complex. Science. 342(6160). 1240585–1240585. 104 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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