Simon C. Afford

6.4k citations

114 papers · 4.6k indexed · h-index 36

Impact in

Hepatology top 0.5%
- Liver Disease and Transplantation
- Liver physiology and pathology
- Liver Diseases and Immunity
Immunology top 2%
- Immune Cell Function and Interaction

Papers in

Hepatology 60
- Liver Disease and Transplantation 30
- Liver physiology and pathology 23
- Liver Diseases and Immunity 11
Surgery 52
- Organ Transplantation Techniques and Outcomes 42
- Cholangiocarcinoma and Gallbladder Cancer Studies 7

Co-authors: David Adams Stefan G. Hübscher Ricky H. Bhogal Hynek Mergental Darius F. Mirza Yuri L. Boteon Lawrence S. Young Robert A. Stockley
Journals: Liver Transplantation (10 papers)Clinical Science (6 papers)PLoS ONE (6 papers)Hepatology (5 papers)Gut (4 papers)
Partner nations: United Kingdom United States Netherlands

In The Last Decade

Simon C. Afford

113 papers receiving 4.5k citations

Peers

Countries citing papers authored by Simon C. Afford

Since Specialization

Citations

This map shows the geographic impact of Simon C. Afford's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon C. Afford with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon C. Afford more than expected).

Fields of papers citing papers by Simon C. Afford

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon C. Afford. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon C. Afford. The network helps show where Simon C. Afford may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Simon C. Afford, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simon C. Afford Line = papers co-authored together Simon C. Afford links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A reproducible extended ex-vivo normothermic machine liver perfusion protocol utilising improved nutrition and targeted vascular flows SHILAP Revista de lepidopterología ·George L. Clarke, Zelin Anggarini, Angus Hann, G. Klein, Amita Gupta, Olmedo Proaño, Zi‐wei Wang, Noor Aini Mohamad Yusoff, Nick Murphy, Mansoor N. Bangash, A.L. Casey, Domenica R. Fertal, Alexander J. Lawson, B. Dasari, M. Thamara P. R. Perera, Hynek Mergental, Simon C. Afford	2024	2
2	N-acetylcysteine: a novel approach to methaemoglobinaemia in normothermic liver machine perfusion Scientific Reports ·George L. Clarke, Jingwen Mao, G. Klein, Angus Hann, Amita Gupta, Olmedo Proaño, Margita Hulmanová, Noor Aini Mohamad Yusoff, Nick Murphy, Mansoor N. Bangash, A.L. Casey, (unknown), Alexander J. Lawson, B. Dasari, M. Thamara P. R. Perera, Hynek Mergental, Simon C. Afford	2023	2
3	Discarded livers tested by normothermic machine perfusion in the VITTAL trial: Secondary end points and 5-year outcomes Liver Transplantation ·Hynek Mergental, Richard W. Laing, Amanda Kirkham, George L. Clarke, Yuri L. Boteon, Darren Barton, Desley Neil, John Isaac, Keith Roberts, Manuel Abradelo, Andrea Schlegel, B. Dasari, James Ferguson, Hentie Cilliers, C.G. Morris, Peter J. Friend, Christina Yap, Simon C. Afford, M. Thamara P. R. Perera, Darius F. Mirza	2023	16
4	The effect of end-ischaemic normothermic machine perfusion on donor hepatic artery endothelial integrity Langenbeck s Archives of Surgery ·Joseph Attard, Dimitri Sneiders, Richard W. Laing, Yuri L. Boteon, Hynek Mergental, John Isaac, Darius F. Mirza, Simon C. Afford, Hermien Hartog, Desley Neil, M. Thamara P. R. Perera	2022	7
5	How Machine Perfusion Ameliorates Hepatic Ischaemia Reperfusion Injury International Journal of Molecular Sciences ·George L. Clarke, Hynek Mergental, Angus Hann, M. Thamara P. R. Perera, Simon C. Afford, Darius F. Mirza	2021	13
6	A Runaway PRH/HHEX-Notch3–Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition Cancer Research ·Philip Kitchen, S. K. Cho, Érico das Chagas Caperuto, Jian Zhiju, Russell A. Leinbach, Dian Septi Wijiastuti, Jutamaad Satayavivad, Sebastian Oltean, Simon C. Afford, Kevin Gaston, Padma-Sheela Jayaraman	2019	15
7	Systematic Review: Clinical Metabolomics to Forecast Outcomes in Liver Transplantation Surgery OMICS A Journal of Integrative Biology ·Joseph Attard, Warwick B. Dunn, Hynek Mergental, Darius F. Mirza, Simon C. Afford, M. Thamara P. R. Perera	2019	13
8	CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism Cancers ·Russell A. Leinbach, Jacques Nw, Dian Septi Wijiastuti, Кира Павловна Афонина, Ka Lee, Philip Kitchen, Simon C. Afford, Kevin Gaston, G. Buehkremer, Jutamaad Satayavivad	2018	39
9	Impact of machine perfusion of the liver on post-transplant biliary complications: A systematic review World Journal of Transplantation ·Yuri L. Boteon, Nova Nurhidayanti, Joseph Attard, Lorraine Wallace, Ricky H. Bhogal, Simon C. Afford	2018	16
10	Viability testing and transplantation of marginal livers (VITTAL) using normothermic machine perfusion: study protocol for an open-label, non-randomised, prospective, single-arm trial BMJ Open ·Richard W. Laing, Hynek Mergental, Christina Yap, Amanda Kirkham, J-L. Gomez-Pincheti, Darren Barton, Stuart M. Curbishley, Yuri L. Boteon, Desley Neil, Stefan G. Hübscher, M. Thamara P. R. Perera, Paolo Muiesan, John Isaac, Keith Roberts, Hentie Cilliers, Simon C. Afford, Darius F. Mirza	2017	90
11	OC-033 The Tweak And Fn14 Pathway As Potential Mediator Of Liver Fibrosis Gut ·A Wilhelm, Kimminsoo, E Humphreys, David Adams, Linda C. Burkly, Simon C. Afford, W Wrodycki	2014	1
12	PMO-131 FGF inducible protein 14 is upregulated in neovessels during chronic inflammatory liver disease and promotes intrahepatic endothelial cell angiogenesis in vitro following stimulation via tweak Gut ·Kimminsoo, E Humphreys, A Wilhelm, Barney Stephenson, Jorge Caamaño, Linda C. Burkly, David Adams, Simon C. Afford	2012	1
13	Reply: Blockade of Janus kinase 2 signaling ameliorates mouse liver damage due to ischemia and reperfusion Liver Transplantation ·Ricky H. Bhogal, Simon C. Afford	2010	1
14	Demystified … Molecular Pathology ·Simon C. Afford, (unknown)	2000	112
15	CD40 Activation Induces Apoptosis in Cultured Human Hepatocytes via Induction of Cell Surface Fas Ligand Expression and Amplifies Fas-mediated Hepatocyte Death during Allograft Rejection The Journal of Experimental Medicine ·Simon C. Afford, 康吉横畠, Aristides G. Eliopoulos, Stefan G. Hübscher, Lawrence S. Young, David Adams	1999	157
16	Fas/Fas Ligand Interaction in Human Colorectal Hepatic Metastases American Journal Of Pathology ·周小珊, Simon C. Afford, 康吉横畠, Stefan G. Hübscher, David Adams	1999	83
17	Effect of peritransplant FTY720 alone or in combination with post-transplant tacrolimus in a rat model of cardiac allotransplantation Transplant International ·Min Xu, Jacques Pirenne, Efstathios Antoniou, Simon C. Afford, Gia Kuop Nguyen, P McMaster	1998	19
18	Ontogeny of Hepatocyte Growth Factor (HGF) and Its Receptor (c-met) in Human Placenta American Journal Of Pathology ·David Somerset, Xiaofeng Li, Simon C. Afford, Alastair J. Strain, Eliana Cristina Campos, Keyan Zhai, Martin Whittle, Mark D. Kilby	1998	50
19	Effects of hepatocyte growth factor on differentiation and cMET receptor expression in the promyelocytic HL60 cell line Molecular Pathology ·Simon C. Afford, Ярославцева, J Oates, J Crocker, Alastair J. Strain	1995	2
20	Extracellular Proteolysis of Fibronectin by Neutrophils: Characterization and the Effects of Recombinant Cytokines American Journal of Respiratory Cell and Molecular Biology ·Anita Chamba, Simon C. Afford, Robert A. Stockley, David Burnett	1991	20

About Simon C. Afford

Simon C. Afford is a scholar working on Hepatology, Surgery, Cancer Research, Immunology and Epidemiology, having authored 114 papers that have together received 4.6k indexed citations. Recurring topics across this work include Organ Transplantation Techniques and Outcomes (42 papers), Liver Disease and Transplantation (30 papers), Liver physiology and pathology (23 papers), Liver Disease Diagnosis and Treatment (20 papers), Organ Donation and Transplantation (13 papers), Protease and Inhibitor Mechanisms (11 papers), Liver Diseases and Immunity (11 papers) and Cholangiocarcinoma and Gallbladder Cancer Studies (7 papers). The work is most often cited by research in Hepatology (1.9k citations), Immunology (1.1k citations), Transplantation (129 citations), Surgery (1.6k citations) and Epidemiology (1.1k citations). Simon C. Afford has collaborated with scholars based in United Kingdom, United States and Netherlands. Frequent co-authors include David Adams, Stefan G. Hübscher, Ricky H. Bhogal, Hynek Mergental, Darius F. Mirza, Yuri L. Boteon, Lawrence S. Young, Robert A. Stockley, Gary Reynolds and Stuart M. Curbishley. Their work appears in journals such as Liver Transplantation, Clinical Science, PLoS ONE, Hepatology and Gut.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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