Simak Ali

17.8k total citations · 4 hit papers
157 papers, 11.8k citations indexed

About

Simak Ali is a scholar working on Molecular Biology, Genetics and Oncology. According to data from OpenAlex, Simak Ali has authored 157 papers receiving a total of 11.8k indexed citations (citations by other indexed papers that have themselves been cited), including 92 papers in Molecular Biology, 68 papers in Genetics and 60 papers in Oncology. Recurrent topics in Simak Ali's work include Estrogen and related hormone effects (58 papers), Cancer-related Molecular Pathways (17 papers) and Genomics and Chromatin Dynamics (16 papers). Simak Ali is often cited by papers focused on Estrogen and related hormone effects (58 papers), Cancer-related Molecular Pathways (17 papers) and Genomics and Chromatin Dynamics (16 papers). Simak Ali collaborates with scholars based in United Kingdom, United States and France. Simak Ali's co-authors include R. Charles Coombes, Paul Pace, Pierre Chambon, Daniel Metzger, Jean‐Marc Bornert, Robert A. Campbell, Harikrishna Nakshatri, Poornima Bhat‐Nakshatri, Nikhil Patel and Jianzhong Shou and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Simak Ali

151 papers receiving 11.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

2012 1.3k citations Caryn S. Ross-Innes, Rory Stark et al. Nature profile →
Mechanisms of Tamoxifen Resistance: Increased Estrogen Receptor-HER2/neu Cross-Talk in ER/HER2-Positive Breast Cancer

2004 918 citations Simak Ali et al. profile →
Phosphatidylinositol 3-Kinase/AKT-mediated Activation of Estrogen Receptor α

2001 777 citations Simak Ali et al. profile →
Endocrine-responsive breast cancer and strategies for combating resistance

2002 696 citations Simak Ali, R. Charles Coombes profile →

Peers

Countries citing papers authored by Simak Ali

Since Specialization

Citations

This map shows the geographic impact of Simak Ali's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simak Ali with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simak Ali more than expected).

Fields of papers citing papers by Simak Ali

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simak Ali. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simak Ali. The network helps show where Simak Ali may publish in the future.

Co-authorship network of co-authors of Simak Ali

This figure shows the co-authorship network connecting the top 25 collaborators of Simak Ali. A scholar is included among the top collaborators of Simak Ali based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Simak Ali. Simak Ali is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	TRIM24 as a therapeutic target in endocrine treatment–resistant breast cancer 2025 ·Proceedings of the National Academy of Sciences ·(unknown), (unknown), (unknown), (unknown), (unknown), Daniela Bossi, Tesa Severson, Joseph C. Siefert, Arianna Calcinotto, Laki Buluwela, Maria Donaldson Collier, Simak Ali, Leonie S. Young, Jean‐Philippe Theurillat, Damir Varešlija, Wilbert Zwart	0
2	Resistance to CDK7 inhibitors directed by acquired mutation of a conserved residue in cancer cells 2025 ·The EMBO Journal ·Chun‐Fui Lai, (unknown), (unknown), Charlotte L. Bevan, R. Charles Coombes, Basil J. Greber, Laki Buluwela, Simak Ali	0
3	High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design 2024 ·Nature Communications ·(unknown), (unknown), Junjie Feng, (unknown), (unknown), Sebastian H. B. Kroll, Marion Barbazanges, Bodo Scheiper, (unknown), Anthony G. M. Barrett, Simak Ali, Abhay Kotecha, Basil J. Greber	21
4	Selective inhibition of CDK9 in triple negative breast cancer 2023 ·Oncogene ·(unknown), Geraldine Laven‐Law, (unknown), Van T.M. Nguyen, Simak Ali, (unknown), Richard Iggo, (unknown), (unknown), Shudong Wang, (unknown), Amy R. Dwyer, Wayne D. Tilley, Theresa E. Hickey	10
5	The Evolution of Affordable Technologies in Liquid Biopsy Diagnostics: The Key to Clinical Implementation 2023 ·Cancers ·(unknown), (unknown), Rebecca C. Allsopp, (unknown), (unknown), (unknown), Simak Ali, R. Charles Coombes, C. Toumazou, Jacqui Shaw, Melpomeni Kalofonou	16
6	Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer 2022 ·British Journal of Cancer ·Daniel Fernández-García, Georgios Nteliopoulos, Robert Hastings, (unknown), Karen Page, Rebecca C. Allsopp, (unknown), Kelly Gleason, David S. Guttery, Simak Ali, R. Charles Coombes, Jacqui Shaw	9
7	Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer 2022 ·Oncogene ·Simon C. Baker, Andrew S. Mason, (unknown), (unknown), Andrew Macdonald, (unknown), Reuben S. Harris, Tim R. Fenton, Manikandan Periyasamy, Simak Ali, Jennifer Southgate	26
8	Genome engineering for estrogen receptor mutations reveals differential responses to anti-estrogens and new prognostic gene signatures for breast cancer 2022 ·Oncogene ·Alison Harrod, Chun‐Fui Lai, (unknown), (unknown), (unknown), Daniela Barsotti Santos, Balázs Győrffy, Rebecca C. Allsopp, Bradley Toghill, K. Balachandran, Mandy Lawson, Christopher J. Morrow, (unknown), Larissa S. Carnevalli, Pei Zhang, David S. Guttery, Jacqui Shaw, R. Charles Coombes, Lakjaya Buluwela, Simak Ali	17
9	Circulating Tumor DNA Profiling From Breast Cancer Screening Through to Metastatic Disease 2021 ·JCO Precision Oncology ·Karen Page, Luke Martinson, Daniel Fernández-García, Allison Hills, Kelly Gleason, (unknown), (unknown), Georgios Nteliopoulos, Robert Hastings, Kate Goddard, (unknown), (unknown), Lindsay Primrose, Mark R. Openshaw, David S. Guttery, Carlo Palmieri, Simak Ali, Justin Stebbing, R. Charles Coombes, Jacqui Shaw	22
10	A novel hotspot specific isothermal amplification method for detection of the common PIK3CA p.H1047R breast cancer mutation 2020 ·Scientific Reports ·Melpomeni Kalofonou, Kenny Malpartida-Cardenas, (unknown), Jesús Rodríguez-Manzano, Ling‐Shan Yu, Nicholas Miscourides, Rebecca C. Allsopp, Kelly Gleason, (unknown), Daniel Fernández-García, Karen Page, Pantelis Georgiou, Simak Ali, R. Charles Coombes, Jacqui Shaw, C. Toumazou	36
11	Induction of APOBEC3B expression by chemotherapy drugs is mediated by DNA-PK-directed activation of NF-κB 2020 ·Oncogene ·Manikandan Periyasamy, Anup K. Singh, Carolina Gemma, (unknown), Rebecca C. Allsopp, Jacqui Shaw, Sara Charmsaz, Leonie S. Young, Paula Cunnea, R. Charles Coombes, Balázs Győrffy, Lakjaya Buluwela, Simak Ali	16
12	ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment 2018 ·Molecular Cancer Therapeutics ·Hetal Patel, Manikandan Periyasamy, Georgina P. Sava, (unknown), B. W. Slafer, Sebastian H. B. Kroll, Marion Barbazanges, (unknown), Silvia Ottaviani, Alison Harrod, Eric O. Aboagye, Laki Buluwela, Matthew J. Fuchter, Anthony G. M. Barrett, R. Charles Coombes, Simak Ali	111
13	CT7001, a Novel Orally Bio-Available CDK7 Inhibitor, Is Highly Active in in-Vitro and in-Vivo Models of AML 2017 ·Blood ·Kristopher Clark, Edward Ainscow, (unknown), Stuart Thomson, Andrew J. Leishman, Elaine Sullivan, Simak Ali, R. Charles Coombes, Anthony G. M. Barrett, (unknown)	15
14	Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts 2016 ·Clinical Cancer Research ·Jacqui Shaw, David S. Guttery, Allison Hills, Daniel Fernández-García, Karen Page, Brenda Rosales, Kate Goddard, Robert Hastings, Jinli Luo, Olivia Ogle, Laura Woodley, Simak Ali, Justin Stebbing, R. Charles Coombes	171
15	SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer 2015 ·Clinical Cancer Research ·Wilbert Zwart, Koen D. Flach, (unknown), Tarek M.A. Abdel-Fatah, Ondřej Gojiš, Sander Canisius, David T. Moore, Ekaterina Nevedomskaya, Mark Opdam, Marjolein Droog, Ingrid Hofland, Stephen Chan, Jacqui Shaw, Ian O. Ellis, R. Charles Coombes, Jason S. Carroll, Simak Ali, Carlo Palmieri	14
16	Differential oestrogen receptor binding is associated with clinical outcome in breast cancer breakdown → 2012 ·Nature ·Caryn S. Ross-Innes, Rory Stark, Andrew E. Teschendorff, Kelly A. Holmes, H. Raza Ali, Mark Dunning, Gordon D. Brown, Ondřej Gojiš, Ian O. Ellis, Andrew R. Green, Simak Ali, Suet‐Feung Chin, Carlo Palmieri, Carlos Caldas, Jason S. Carroll	1304
17	The Development of a Selective Cyclin-Dependent Kinase Inhibitor That Shows Antitumor Activity 2009 ·Cancer Research ·Simak Ali, Dean A. Heathcote, Sebastian H. B. Kroll, Ashutosh S. Jogalekar, Bodo Scheiper, Hetal Patel, Jan Bräckow, (unknown), Matthew J. Fuchter, Manikandan Periyasamy, Robert S. Tolhurst, (unknown), James P. Snyder, Dennis C. Liotta, Eric O. Aboagye, Anthony G. M. Barrett, R. Charles Coombes	129
18	Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: a double-blind placebo-controlled phase II randomised trial 2005 ·The Lancet Oncology ·Andreas Polychronis, H D Sinnett, Dimitri Hadjiminas, Hemant Singhal, Janine Mansi, (unknown), Sami Shousha, Jie Jiang, David Peston, Nigel Barrett, David M. Vigushin, (unknown), (unknown), Simak Ali, Martin J. Slade, R. Charles Coombes	160
19	Phosphorylation of Human Estrogen Receptor α by Protein Kinase A Regulates Dimerization 1999 ·Molecular and Cellular Biology ·Dongsheng Chen, Paul Pace, R. Charles Coombes, Simak Ali	199
20	Abstracts of papers presented at the 13th Mammalian Molecular and Biochemical Genetics Workshop held at the Linnean Society Rooms, Piccadilly, London on 26 and 27 November 1986 1987 ·Genetics Research ·Simak Ali, Anthony Clark, Alan Archibald, Pierre Boursot, Hiromichi Yonekawa, François Bonhomme, David G. Wilkinson, Janet E. Champion, (unknown), Andrew McMahon	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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