Siew Pheng Lim

6.8k citations

75 papers · 5.3k indexed · h-index 43

Virology top 0.5%
- HIV Research and Treatment 31
Public Health, Environmental and Occupational Health top 0.2%
- Mosquito-borne diseases and control 49
- Malaria Research and Control 23
Infectious Diseases top 0.5%
- Viral Infections and Vectors 15
- Viral Infections and Outbreaks Research 5
Insect Science top 1%
- Insect symbiosis and bacterial influences 15
Hepatology top 2%
- Hepatitis C virus research 12
Immunology
- Immune Cell Function and Interaction 5

Co-authors: Pei‐Yong Shi Subhash G. Vasudevan Christian G. Noble Hongping Dong Julien Lescar Thomas H. Keller Zheng Yin David Beer
Cited by: Virology Public Health, Environmental and Occupational Health Infectious Diseases
Journals: Proceedings of the National Academy of Sciences (1 paper)Journal of Biological Chemistry (6 papers)Angewandte Chemie International Edition (1 paper)
Partner nations: Singapore Switzerland United States

In The Last Decade

Siew Pheng Lim

75 papers receiving 5.2k citations

Peers

Countries citing papers authored by Siew Pheng Lim

Since Specialization

Citations

This map shows the geographic impact of Siew Pheng Lim's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Siew Pheng Lim with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Siew Pheng Lim more than expected).

Fields of papers citing papers by Siew Pheng Lim

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Siew Pheng Lim. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Siew Pheng Lim. The network helps show where Siew Pheng Lim may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Siew Pheng Lim, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Siew Pheng Lim Line = papers co-authored together Siew Pheng Lim links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Targeting SARS-CoV-2 and host cell receptor interactions Antiviral Research ·Siew Pheng Lim	2022	14
2	Structure-activity relationship of uridine-based nucleoside phosphoramidate prodrugs for inhibition of dengue virus RNA-dependent RNA polymerase Bioorganic & Medicinal Chemistry Letters ·Gang Wang,Siew Pheng Lim,Yen‐Liang Chen,Jürg Hunziker,Ranga Rao,Feng Gu,Cheah C. Seh,Nahdiyah Abdul Ghafar,Haoying Xu,Katherine Chan,Xiaodong Lin,Oliver L. Saunders,Martijn Fenaux,Weidong Zhong,Pei‐Yong Shi,Fumiaki Yokokawa	2018	20
3	Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling PLoS Pathogens ·Siew Pheng Lim,Christian G. Noble,Cheah C. Seh,Tingjin Sherryl Soh,Abbas El Sahili,Grace Kar Yarn Chan,Julien Lescar,Rishi Arora,Timothy E. Benson,Shahul Nilar,Ujjini H. Manjunatha,Kah Fei Wan,Hongping Dong,Xuping Xie,Pei‐Yong Shi,Fumiaki Yokokawa	2016	140
4	Stabilization of dengue virus polymerase in de novo initiation assay provides advantages for compound screening Antiviral Research ·Pornwaratt Niyomrattanakit,Kah Fei Wan,Ka Yan Chung,Siti Nurdiana Abas,Cheah C. Seh,Hongping Dong,Chin Chin Lim,Alexander T. Chao,Chang Bok Lee,Shahul Nilar,Julien Lescar,Pei‐Yong Shi,David Beer,Siew Pheng Lim	2015	16
5	A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication PLoS Pathogens ·Yongqian Zhao,Tingjin Sherryl Soh,Jie Zheng,Kitti Wing Ki Chan,Wint Wint Phoo,Chin Chin Lee,Moon Y. F. Tay,Kunchithapadam Swaminathan,Tobias Cornvik,Siew Pheng Lim,Pei‐Yong Shi,Julien Lescar,Subhash G. Vasudevan,Dahai Luo	2015	214
6	Identifying Initiation and Elongation Inhibitors of Dengue Virus RNA Polymerase in a High-Throughput Lead-Finding Campaign SLAS DISCOVERY ·Thomas M. Smith,Siew Pheng Lim,Kimberley Yue,Scott A. Busby,Rishi Arora,Cheah C. Seh,S. Kirk Wright,Razvan Nutiu,Pornwaratt Niyomrattanakit,Kah Fei Wan,David Beer,Pei‐Yong Shi,Timothy E. Benson	2014	19
7	Serotype-specific Differences in Dengue Virus Non-structural Protein 5 Nuclear Localization Journal of Biological Chemistry ·Holger Hannemann,Po-Yu Sung,Han-Chen Chiu,Amjad Yousuf,Jim Bird,Siew Pheng Lim,Andrew D. Davidson	2013	70
8	Ten years of dengue drug discovery: Progress and prospects Antiviral Research ·Siew Pheng Lim,Qing-Yin Wang,Christian G. Noble,Yen‐Liang Chen,Hongping Dong,Bin Zou,Fumiaki Yokokawa,Shahul Nilar,Paul W. Smith,David Beer,Julien Lescar,Pei‐Yong Shi	2013	279
9	2′-O Methylation of Internal Adenosine by Flavivirus NS5 Methyltransferase PLoS Pathogens ·Hongping Dong,David Chang,Maggie Ho Chia Hua,Siew Pheng Lim,Yok Hian Chionh,Fabian Hia,Yie Hou Lee,Petra Kukkaro,Shee‐Mei Lok,Peter C. Dedon,Pei‐Yong Shi	2012	118
10	Structural and Functional Analyses of a Conserved Hydrophobic Pocket of Flavivirus Methyltransferase Journal of Biological Chemistry ·Hongping Dong,Lihui Liu,Gang Zou,Yiwei Zhao,Zhong Li,Siew Pheng Lim,Pei‐Yong Shi,Hongmin Li	2010	49
11	Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2′-O methyltransferase activity in dengue virus Virology ·Ka Yan Chung,Hongping Dong,Alexander T. Chao,Pei‐Yong Shi,Julien Lescar,Siew Pheng Lim	2010	53
12	Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein The EMBO Journal ·Dahai Luo,Ting Xu,R.P. Watson,Daniella Scherer-Becker,Aruna Sampath,Wolfgang Jahnke,S.S. Yeong,Chern Hoe Wang,Siew Pheng Lim,Alex Y. Strongin,Subhash G. Vasudevan,Julien Lescar	2008	197
13	Cell‐Free Transcription/Translation from PCR‐Amplified DNA for High‐Throughput NMR Studies Angewandte Chemie International Edition ·Peter Wu,Kiyoshi Ozawa,Siew Pheng Lim,Subhash G. Vasudevan,Nicholas E. Dixon,Gottfried Otting	2007	70
14	Purification and crystallization of dengue and West Nile virus NS2B–NS3 complexes Acta Crystallographica Section F Structural Biology and Crystallization Communications ·A. D’Arcy,Maxime Chaillet,Nikolaus Schiering,Frédéric Villard,Siew Pheng Lim,Peggy Lefeuvre,P. Erbel	2006	16
15	Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus Nature Structural & Molecular Biology ·P. Erbel,Nikolaus Schiering,A. D’Arcy,Martin Renatus,M. Kroemer,Siew Pheng Lim,Zheng Yin,Thomas H. Keller,Subhash G. Vasudevan,Ulrich Hommel	2006	458
16	Identification of a new HLA‐A2464 variant in the Singapore Chinese population† Tissue Antigens* ·Siew Pheng Lim,S. H. Chen,E. C. Ren	2006	2
17	Functional Profiling of Recombinant NS3 Proteases from All Four Serotypes of Dengue Virus Using Tetrapeptide and Octapeptide Substrate Libraries Journal of Biological Chemistry ·Jun Li,Siew Pheng Lim,David Beer,Viral Patel,Daying Wen,Christine Tumanut,David C. Tully,Jennifer Williams,Jan Jiřiček,John P. Priestle,Jennifer L. Harris,Subhash G. Vasudevan	2005	208
18	Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors Bioorganic & Medicinal Chemistry Letters ·Zheng Yin,Sejal Patel,Weiling Wang,Wai-Ling Chan,K. R. Ranga Rao,Gang Wang,Xinyi Ngew,Viral Patel,David Beer,John E. Knox,Ngai Ling,Claus Ehrhardt,Siew Pheng Lim,Subhash G. Vasudevan,Thomas H. Keller	2005	128
19	Differential polarization of immune responses by co-administration of antigens with chemokines Vaccine ·Achim Frauenschuh,A.L. DeVico,Siew Pheng Lim,R C Gallo,Alfredo Garzino‐Demo	2004	19
20	The Hepatitis C Virus Core Protein Interacts with NS5A and Activates Its Caspase-Mediated Proteolytic Cleavage Virology ·Phuay‐Yee Goh,Yee‐Joo Tan,Siew Pheng Lim,Seng Gee Lim,Yuen Tan,Wan Jin Hong	2001	52

About Siew Pheng Lim

Siew Pheng Lim is a scholar working on Virology, Public Health, Environmental and Occupational Health and Hepatology, having authored 75 papers that have together received 5.3k indexed citations. Recurring topics across this work include Mosquito-borne diseases and control (49 papers), HIV Research and Treatment (31 papers), Malaria Research and Control (23 papers), Insect symbiosis and bacterial influences (15 papers), Viral Infections and Vectors (15 papers), Hepatitis C virus research (12 papers), Viral Infections and Outbreaks Research (5 papers) and Immune Cell Function and Interaction (5 papers). The work is most often cited by research in Virology (1.1k citations), Public Health, Environmental and Occupational Health (3.7k citations) and Infectious Diseases (2.0k citations). Siew Pheng Lim has collaborated with scholars based in Singapore, Switzerland and United States. Frequent co-authors include Pei‐Yong Shi, Subhash G. Vasudevan, Christian G. Noble, Hongping Dong, Julien Lescar, Julien Lescar, Thomas H. Keller, Zheng Yin, David Beer and Dahai Luo. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Angewandte Chemie International Edition.

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