Shosaku Numa

34.4k citations

187 papers · 27.9k indexed · 20 hit papers · h-index 78

Molecular Biology top 0.05%
Cellular and Molecular Neuroscience top 0.02%
Cardiology and Cardiovascular Medicine top 0.5%
Physiology top 0.5%
Cell Biology top 0.5%

Co-authors: Masaharu Noda Tadaaki Hirose Hideo Takahashi Tsutomu Tanabe Shigetada Nakanishi Keiji Imoto Masayoshi Mishina Seiichi Inayama
Topics: Ion channel regulation and function (52 papers)Receptor Mechanisms and Signaling (40 papers)Metabolism and Genetic Disorders (28 papers)
Cited by: Cellular and Molecular Neuroscience Molecular Biology Behavioral Neuroscience
Journals: Nature Proceedings of the National Academy of Sciences Nucleic Acids Research
Partner nations: Japan Germany United States

In The Last Decade

Shosaku Numa

185 papers receiving 26.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursor

1979 1.4k citations Shigetada Nakanishi, Shosaku Numa et al. Nature profile →
Primary structure of the receptor for calcium channel blockers from skeletal muscle

1987 1.1k citations Tsutomu Tanabe, Hiroshi Takeshima et al. Nature profile →
Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence

1984 1.0k citations Masaharu Noda, Tsutomu Tanabe et al. Nature profile →
Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor

1989 968 citations Hiroshi Takeshima, Seiichiro Nishimura et al. Nature profile →
Structural parts involved in activation and inactivation of the sodium channel

1989 942 citations Walter Stühmer, Franco Conti et al. Nature profile →
Molecular distinction between fetal and adult forms of muscle acetylcholine receptor

1986 791 citations Masayoshi Mishina, Keiji Imoto et al. Nature profile →
Existence of distinct sodium channel messenger RNAs in rat brain

1986 782 citations Masaharu Noda, Toshiaki Kayano et al. Nature profile →
Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

1986 764 citations Tai Kubo, Kazuhiko Fukuda et al. Nature profile →
Cloning and sequence analysis of cDNA for bovine adrenal preproenkephalin

1982 761 citations Masaharu Noda, Tadaaki Hirose et al. Nature profile →
Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

1989 759 citations Atsushi Mikami, Keiji Imoto et al. Nature profile →
Primary structure and functional expression from complementary DNA of a brain calcium channel

1991 729 citations Yasuo Mori, Thomas Friedrich et al. Nature profile →
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

1988 643 citations Keiji Imoto, Christopher Büsch et al. Nature profile →
Cloning and sequence analysis of cDNA for porcine β-neo-endorphin/dynorphin precursor

1982 634 citations Masaharu Noda, Tadaaki Hirose et al. Nature profile →
Structural homology of Torpedo californica acetylcholine receptor subunits

1983 621 citations Masaharu Noda, Tsutomu Tanabe et al. Nature profile →
Calcium channel characteristics conferred on the sodium channel by single mutations

1992 603 citations Stefan H. Heinemann, Heinrich Terlau et al. Nature profile →
Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence

1982 557 citations Masaharu Noda, Tsutomu Tanabe et al. Nature profile →
Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel

1989 520 citations U. Benjamin Kaupp, Tetsuhiro Niidome et al. Nature profile →
Regions of the skeletal muscle dihydropyridine receptor critical for excitation–contraction coupling

1990 512 citations Tsutomu Tanabe, Kurt G. Beam et al. Nature profile →
Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

1986 470 citations Shosaku Numa, Bert Sakmann et al. Pflügers Archiv - European Journal of Physiology profile →
Location of a δ-subunit region determining ion transport through the acetylcholine receptor channel

1986 261 citations Keiji Imoto, Bert Sakmann et al. Nature profile →

Peers

Countries citing papers authored by Shosaku Numa

Since Specialization

Citations

This map shows the geographic impact of Shosaku Numa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shosaku Numa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shosaku Numa more than expected).

Fields of papers citing papers by Shosaku Numa

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shosaku Numa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shosaku Numa. The network helps show where Shosaku Numa may publish in the future.

Co-authorship network of co-authors of Shosaku Numa

This figure shows the co-authorship network connecting the top 25 collaborators of Shosaku Numa. A scholar is included among the top collaborators of Shosaku Numa based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shosaku Numa. Shosaku Numa is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Determinants of sensitivity to tetrodotoxin and saxitoxin of sodium channel-II. 1992 ·The FASEB Journal ·Heinrich Terlau,Stefan H. Heinemann,Walter Stuehmer,Michael Pusch,Franco Conti,Keiji Imoto,Shosaku Numa	1
2	Function of a truncated dihydropyridine receptor as both voltage sensor and calcium channel 1992 ·Nature ·Kurt G. Beam,Brett Adams,Tetsuhiro Niidome,Shosaku Numa,Tsutomu Tanabe	82
3	Single point mutations of the sodium channel drastically reduce the pore permeability without preventing its gating 1991 ·European Biophysics Journal ·Michael Pusch,Masaharu Noda,Walter Stühmer,Shosaku Numa,Franco Conti	54
4	Repeat I of the dihydropyridine receptor is critical in determining calcium channel activation kinetics 1991 ·Nature ·Tsutomu Tanabe,Brett Adams,Shosaku Numa,Kurt G. Beam	117
5	Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II 1991 ·FEBS Letters ·Heinrich Terlau,Stefan H. Heinemann,Walter Stühmer,Michael Pusch,Franco Conti,Keiji Imoto,Shosaku Numa	391
6	A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor 1991 ·FEBS Letters ·Keiji Imoto,Takashi Konno,Junichi Nakai,(unknown),Masayoshi Mishina,Shosaku Numa	110
7	Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel 1991 ·Proceedings of the Royal Society B Biological Sciences ·Takashi Konno,Christopher Büsch,Eberhard von Kitzing,Keiji Imoto,(unknown),Junichi Nakai,Masayoshi Mishina,Shosaku Numa,Bert Sakmann	107
8	Primary structure and functional expression from complementary DNA of a brain calcium channelbreakdown → 1991 ·Nature ·Yasuo Mori,Thomas Friedrich,(unknown),Atsushi Mikami,Junichi Nakai,Peter Ruth,Eva Bosse,Franz Hofmann,Veit Flockerzi,Teiichi Furuichi,Katsuhiko Mikoshiba,Keiji Imoto,Tsutomu Tanabe,Shosaku Numa	729
9	Spontaneous and agonist-induced openings of an acetylcholine receptor channel composed of bovine muscle ?-, ? and ?-subunits 1990 ·Pflügers Archiv - European Journal of Physiology ·Meyer B. Jackson,Keiji Imoto,(unknown),Takashi Konno,Shosaku Numa,Bert Sakmann	44
10	Cardiac-type excitation-contraction coupling in dysgenic skeletal muscle injected with cardiac dihydropyridine receptor cDNA 1990 ·Nature ·Tsutomu Tanabe,Atsushi Mikami,Shosaku Numa,Kurt G. Beam	202
11	Intramembrane charge movement restored in dysgenic skeletal muscle by injection of dihydropyridine receptor cDNAs 1990 ·Nature ·Brett Adams,Tsutomu Tanabe,Atsushi Mikami,Shosaku Numa,Kurt G. Beam	227
12	Functional expression of the calcium release channel from skeletal muscle ryanodine receptor cDNA 1989 ·FEBS Letters ·Reinhold Penner,Erwin Neher,Hiroshi Takeshima,Seiichiro Nishimura,Shosaku Numa	107
13	Potassium channels from NG108‐15 neuroblastoma‐glioma hybrid cells 1989 ·FEBS Letters ·(unknown),Keiji Imoto,(unknown),Haruhiro Higashida,Naoyuki Iwabe,Takashi Miyata,Shosaku Numa	168
14	Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channelbreakdown → 1989 ·Nature ·U. Benjamin Kaupp,Tetsuhiro Niidome,(unknown),S. Terada,Wolfgang Bönigk,Walter Stühmer,Neil J. Cook,Kenji Kangawa,Hisayuki Matsuo,Tadaaki Hirose,Takashi Miyata,Shosaku Numa	520
15	Functional expression of cloned cDNA encoding sodium channel III 1988 ·FEBS Letters ·Harukazu Suzuki,Synnöve Beckh,Hideo Kubo,Naoki Yahagi,Hiroyuki Ishida,Toshiaki Kayano,Masaharu Noda,Shosaku Numa	140
16	Primary structure of porcine muscarinic acetylcholine receptor III and antagonist binding studies 1988 ·FEBS Letters ·Isamu Akiba,Tai Kubo,Akito Maeda,Hideaki Bujo,Junichi Nakai,Masayoshi Mishina,Shosaku Numa	82
17	Selective coupling with K+ currents of muscarinic acetylcholine receptor subtypes in NG108-15 cells 1988 ·Nature ·Kazuhiko Fukuda,Haruhiro Higashida,Tai Kubo,Akito Maeda,Isamu Akiba,Hideaki Bujo,(unknown),Shosaku Numa	186
18	[1] Acetyl-CoA carboxylase from rat liver 1981 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Tadashi Tanabe,Shigetada Nakanishi,Takashi Hashimoto,(unknown),Jun‐ichi Nikawa,Shosaku Numa	85
19	Disturbance of fatty acid synthesis in starvation and alloxan diabetes. 1. Fatty acid synthesis in the liver of normal and starved rats. 1961 ·Shosaku Numa,Michio Matsuhashi,Frédéric Lynen	0
20	[On disorders of fatty acid synthesis in hunger and alloxan diabetes. I. Fatty acid synthesis in the liver of normal and fasting rats]. 1961 ·PubMed ·Shosaku Numa,Michio Matsuhashi,Frédéric Lynen	30

About Shosaku Numa

Shosaku Numa is a scholar working on Clinical Biochemistry, Biochemistry and Cellular and Molecular Neuroscience, having authored 187 papers that have together received 27.9k indexed citations. Recurring topics across this work include Ion channel regulation and function (52 papers), Receptor Mechanisms and Signaling (40 papers) and Metabolism and Genetic Disorders (28 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (13.2k citations), Molecular Biology (22.5k citations) and Behavioral Neuroscience (1.2k citations). Shosaku Numa has collaborated with scholars based in Japan, Germany and United States. Frequent co-authors include Masaharu Noda, Tadaaki Hirose, Hideo Takahashi, Tsutomu Tanabe, Shigetada Nakanishi, Keiji Imoto, Masayoshi Mishina, Seiichi Inayama, Hiroshi Takeshima and Walter Stühmer. Their work appears in journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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