Shixian Lin

3.3k total citations · 3 hit papers
52 papers, 2.5k citations indexed

About

Shixian Lin is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Shixian Lin has authored 52 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 39 papers in Molecular Biology, 17 papers in Organic Chemistry and 8 papers in Oncology. Recurrent topics in Shixian Lin's work include Click Chemistry and Applications (17 papers), RNA and protein synthesis mechanisms (12 papers) and Ubiquitin and proteasome pathways (9 papers). Shixian Lin is often cited by papers focused on Click Chemistry and Applications (17 papers), RNA and protein synthesis mechanisms (12 papers) and Ubiquitin and proteasome pathways (9 papers). Shixian Lin collaborates with scholars based in China, United States and Taiwan. Shixian Lin's co-authors include Peng R. Chen, Shang Jia, Maiyun Yang, Jie Li, Ziyang Hao, Jie Wang, Xiaoyu Zhang, Jingyi Zhao, Yulin Chen and Siqi Zheng and has published in prestigious journals such as Nature, Science and Chemical Reviews.

In The Last Decade

Shixian Lin

47 papers receiving 2.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Palladium-triggered deprotection chemistry for protein activation in living cells

2014 386 citations Jingyi Zhao, Shixian Lin et al. profile →
Redox-based reagents for chemoselective methionine bioconjugation

2017 382 citations Shixian Lin, Xiaoyu Yang et al. Science profile →
AARS1 and AARS2 sense l-lactate to regulate cGAS as global lysine lactyltransferases

2024 151 citations Heyu Li, Chao Liu et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Shixian Lin China	25	1.9k	1.0k	294	278	273	52	2.5k
Isaac S. Carrico United States	18	1.4k 0.7×	856 0.8×	377 1.3×	200 0.7×	235 0.9×	28	2.0k
Carston R. Wagner United States	36	2.6k 1.4×	655 0.6×	300 1.0×	232 0.8×	355 1.3×	129	3.8k
Jacqui Méndez United States	10	2.4k 1.3×	584 0.6×	306 1.0×	163 0.6×	254 0.9×	14	3.0k
John A. W. Kruijtzer Netherlands	31	1.9k 1.0×	886 0.9×	409 1.4×	132 0.5×	313 1.1×	76	3.0k
Marjeta Urh United States	24	3.0k 1.6×	615 0.6×	488 1.7×	210 0.8×	529 1.9×	51	3.8k
Nathan W. Luedtke Switzerland	36	3.1k 1.6×	1.1k 1.1×	190 0.6×	378 1.4×	334 1.2×	92	3.7k
Rachel Friedman Ohana United States	10	1.8k 0.9×	551 0.5×	340 1.2×	182 0.7×	210 0.8×	21	2.4k
Vu Hong United States	11	1.6k 0.8×	1.6k 1.5×	594 2.0×	235 0.8×	196 0.7×	11	2.5k
Tom N. Grossmann Germany	36	4.4k 2.3×	1.6k 1.5×	532 1.8×	267 1.0×	623 2.3×	90	5.1k
Steven H. L. Verhelst Germany	33	2.1k 1.1×	1.2k 1.2×	235 0.8×	124 0.4×	642 2.4×	111	3.3k

Countries citing papers authored by Shixian Lin

Since Specialization

Citations

This map shows the geographic impact of Shixian Lin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shixian Lin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shixian Lin more than expected).

Fields of papers citing papers by Shixian Lin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shixian Lin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shixian Lin. The network helps show where Shixian Lin may publish in the future.

Co-authorship network of co-authors of Shixian Lin

This figure shows the co-authorship network connecting the top 25 collaborators of Shixian Lin. A scholar is included among the top collaborators of Shixian Lin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shixian Lin. Shixian Lin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wang, Bin, Yongqiang Wang, Ting Pan, et al.. (2025). Targeting a key disulfide linkage to regulate RIG-I condensation and cytosolic RNA-sensing. Nature Cell Biology. 27(5). 817–834. 1 indexed citations

Lin, Shixian, Cai‐Guang Yang, Cheng Luo, et al.. (2025). Recent Advances in Dynamic Biomacromolecular Modifications and Chemical Interventions: Perspective from a Chinese Chemical Biology Consortium. CCS Chemistry. 7(10). 2912–2949.

Zhu, Xuefei, Donghui Xia, Yang Liu, et al.. (2024). FOXP1 phosphorylation antagonizes its O-GlcNAcylation in regulating ATR activation in response to replication stress. The EMBO Journal. 44(2). 457–483. 1 indexed citations

Zhu, Tianyi, Hongxia Zhao, Shixian Lin, et al.. (2024). DNA damage-induced proteasome phosphorylation controls substrate recognition and facilitates DNA repair. Proceedings of the National Academy of Sciences. 121(35). e2321204121–e2321204121. 2 indexed citations

Li, Heyu, Chao Liu, Ran Li, et al.. (2024). AARS1 and AARS2 sense l-lactate to regulate cGAS as global lysine lactyltransferases. Nature. 634(8036). 1229–1237. 151 indexed citations breakdown →

Dai, Tong, Lei Zhang, Meirong Zhang, et al.. (2023). MAVS deSUMOylation by SENP1 inhibits its aggregation and antagonizes IRF3 activation. Nature Structural & Molecular Biology. 30(6). 785–799. 26 indexed citations

Lin, Shixian, et al.. (2023). Facile synthesis of β-Ga₂O₃ based high-performance electronic devices via direct oxidation of solution-processed transition metal dichalcogenides. Nanotechnology. 35(12). 125603–125603. 3 indexed citations

Lin, Shixian, Xingwu Zhou, Fanwen Yang, et al.. (2023). Biodegradable double-network GelMA-ACNM hydrogel microneedles for transdermal drug delivery. Frontiers in Bioengineering and Biotechnology. 11. 1110604–1110604. 13 indexed citations

Liu, Chao, Yulin Chen, Long Zhang, et al.. (2023). Computational design and genetic incorporation of lipidation mimics in living cells. Nature Chemical Biology. 20(1). 42–51. 11 indexed citations

10.

Song, Lizhi, Fan Yang, Dandan Zhang, et al.. (2023). SIRT1 deacetylates WEE1 and sensitizes cancer cells to WEE1 inhibition. Nature Chemical Biology. 19(5). 585–595. 23 indexed citations

11.

Qin, Ziran, Zhenyu Ma, Tong Dai, et al.. (2022). Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity. Nature Immunology. 23(8). 1193–1207. 64 indexed citations

12.

Zhao, Hongxia, Wenlong Ding, Jia Zang, et al.. (2021). Directed-evolution of translation system for efficient unnatural amino acids incorporation and generalizable synthetic auxotroph construction. Nature Communications. 12(1). 7039–7039. 49 indexed citations

13.

Zhang, Zhengkui, Xiaojin Wu, Ling Li, et al.. (2020). Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity. Molecular Cell. 79(2). 304–319.e7. 74 indexed citations

14.

Zhang, Miao, Liang Cai, Qinfu Chen, et al.. (2019). Histone H2A phosphorylation recruits topoisomerase II α to centromeres to safeguard genomic stability. The EMBO Journal. 39(3). e101863–e101863. 31 indexed citations

15.

Lin, Shixian, Xiaoyu Yang, Shang Jia, et al.. (2017). Redox-based reagents for chemoselective methionine bioconjugation. Science. 355(6325). 597–602. 382 indexed citations breakdown →

16.

Yang, Yi, Haiping Song, Dan He, et al.. (2016). Genetically encoded protein photocrosslinker with a transferable mass spectrometry-identifiable label. Nature Communications. 7(1). 12299–12299. 72 indexed citations

17.

Yang, Yi, Shixian Lin, Wei Lin, & Peng R. Chen. (2014). Ligand‐Assisted Dual‐Site Click Labeling of EGFR on Living Cells. ChemBioChem. 15(12). 1738–1743. 15 indexed citations

18.

Zhao, Jingyi, Shixian Lin, Yong Huang, Jing Zhao, & Peng R. Chen. (2013). Mechanism-Based Design of a Photoactivatable Firefly Luciferase. Journal of the American Chemical Society. 135(20). 7410–7413. 54 indexed citations

19.

Yang, Maiyun, Yanqun Song, Meng Zhang, et al.. (2012). Converting a Solvatochromic Fluorophore into a Protein‐Based pH Indicator for Extreme Acidity. Angewandte Chemie International Edition. 51(31). 7674–7679. 113 indexed citations

20.

Hao, Ziyang, Yanqun Song, Shixian Lin, et al.. (2011). A readily synthesized cyclic pyrrolysine analogue for site-specific protein “click” labeling. Chemical Communications. 47(15). 4502–4502. 51 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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