Sérgio Simões

9.2k citations

152 papers · 7.3k indexed · 1 hit paper · h-index 48

Impact in

Pharmaceutical Science top 0.2%
- Advanced Drug Delivery Systems
Biomaterials top 0.5%
- Nanoparticle-Based Drug Delivery

Papers in ⓘ

Molecular Biology 92
- RNA Interference and Gene Delivery 69
- Advanced biosensing and bioanalysis techniques 50
- DNA and Nucleic Acid Chemistry 9
Genetics 29
- Virus-based gene therapy research 29

Co-authors: Maria C. Pedroso de Lima (66 shared papers)Nejat Düzgüneş (23 shared papers)Rogério Gaspar (9 shared papers)João Nuno Moreira (44 shared papers)Cristina Fonseca (1 shared paper)Vladimir Slepushkin (13 shared papers)Cláudia Silva (9 shared papers)Henrique Faneca (9 shared papers)
Journals: Journal of Controlled Release (10 papers)Biochimica et Biophysica Acta (BBA) - Biomembranes (9 papers)International Journal of Pharmaceutics (9 papers)European Journal of Pharmaceutics and Biopharmaceutics (6 papers)Molecular Membrane Biology (4 papers)
Partner nations: Portugal United States Poland

In The Last Decade

Sérgio Simões

151 papers receiving 7.1k citations

Hit Papers

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Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity 2002 · 581 citations

Peers

Countries citing papers authored by Sérgio Simões

Since Specialization

Citations

This map shows the geographic impact of Sérgio Simões's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sérgio Simões with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sérgio Simões more than expected).

Fields of papers citing papers by Sérgio Simões

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sérgio Simões. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sérgio Simões. The network helps show where Sérgio Simões may publish in the future.

Co-authors

The 25 scholars most cited alongside Sérgio Simões, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Sérgio Simões Line = papers co-authored together Sérgio Simões links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 152 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity Journal of Controlled Release ·Cristina Fonseca, Sérgio Simões, Rogério Gaspar Hit paper breakdown →	2002	581
2	On the formulation of pH-sensitive liposomes with long circulation times Advanced Drug Delivery Reviews ·Sérgio Simões	2004	379
3	Cationic lipid–DNA complexes in gene delivery: from biophysics to biological applications Advanced Drug Delivery Reviews ·Maria C. Pedroso de Lima, Sérgio Simões, Pedro Pires, Henrique Faneca, Nejat Düzgüneş	2001	294
4	Oral films: Current status and future perspectives Journal of Controlled Release ·Ana Filipa Borges, Cláudia Silva, Jorge F. J. Coelho, Sérgio Simões	2015	244
5	Cationic liposomes for gene delivery Expert Opinion on Drug Delivery ·Sérgio Simões, Ana da Silva Filipe, Henrique Faneca, Miguel Mano, Nuno Penacho, Nejat Düzgüneş, Maria C. Pedroso de Lima	2005	217
6	Lipid-Based Nanoparticles for siRNA Delivery in Cancer Therapy: Paradigms and Challenges Accounts of Chemical Research ·Lígia C. Gomes‐da‐Silva, Nuno A. Fonseca, Vera Moura, Maria C. Pedroso de Lima, Sérgio Simões, João Nuno Moreira	2012	200
7	Sterically Stabilized pH-sensitive Liposomes, INTRACELLULAR DELIVERY OF AQUEOUS CONTENTS AND PROLONGED CIRCULATION IN VIVO Journal of Biological Chemistry ·Vladimir Slepushkin, Sérgio Simões, Paul Dazin, Mary S. Newman, Luke S. S. Guo, Maria C. Pedroso de Lima, Nejat Düzgüneş	1997	188
8	Mechanisms of Singlet‐Oxygen and Superoxide‐Ion Generation by Porphyrins and Bacteriochlorins and their Implications in Photodynamic Therapy Chemistry - A European Journal ·Elsa F. F. Silva, Carlos Serpa, J. Da̧browski, Carlos J. P. Monteiro, Sebastião J. Formosinho, Grażyna Stochel, Krystyna Urbańska, Sérgio Simões, Mariette M. Pereira, Luı́s G. Arnaut	2010	171
9	Quality by design in pharmaceutical manufacturing: A systematic review of current status, challenges and future perspectives European Journal of Pharmaceutics and Biopharmaceutics ·Helena Bigares Grangeia, Cláudia Silva, Sérgio Simões, Marco S. Reis	2019	167
10	Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusigenic peptides Gene Therapy ·Sérgio Simões, Vladimir Slepushkin, Rogério Gaspar, Maria C. Pedroso de Lima, Nejat Düzgüneş	1998	157
11	Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides Gene Therapy ·Sérgio Simões, Vladimir Slepushkin, Pedro Pires, Rogério Gaspar, Maria C. Pedroso de Lima, Nejat Düzgüneş	1999	136
12	Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum Biochimica et Biophysica Acta (BBA) - Biomembranes ·Sérgio Simões, Vladimir Slepushkin, Pedro Pires, Rogério Gaspar, Maria C. Pedroso de Lima, Nejat Düzgüneş	2000	126
13	Cationic Liposomes for Gene Delivery: From Biophysics to Biological Applications Current Medicinal Chemistry ·Maria C. Pedroso de Lima, Sara Neves, Ana da Silva Filipe, (unknown), Sérgio Simões	2003	125
14	On the mechanisms of internalization and intracellular delivery mediated by pH-sensitive liposomes Biochimica et Biophysica Acta (BBA) - Biomembranes ·Sérgio Simões, Vladimir Slepushkin, Nejat Düzgüneş, Maria C. Pedroso de Lima	2001	120
15	Improving chitosan-mediated gene transfer by the introduction of intracellular buffering moieties into the chitosan backbone Acta Biomaterialia ·Cátia Moreira, Hugo Oliveira, Liliana R. Pires, Sérgio Simões, Mário A. Barbosa, Ana Paula Pêgo	2009	117
16	Hot-melt extrusion in the pharmaceutical industry: toward filing a new drug application Drug Discovery Today ·Marta F. Simões, Rui M. A. Pinto, Sérgio Simões	2019	109
17	Interaction of cationic liposomes and their DNA complexes with monocytic leukemia cells Biochimica et Biophysica Acta (BBA) - Biomembranes ·Pedro Pires, Sérgio Simões, Shlomo Nir, Rogério Gaspar, Nejat Düzgüneş, Maria C. Pedroso de Lima	1999	108
18	New Halogenated Water‐Soluble Chlorin and Bacteriochlorin as Photostable PDT Sensitizers: Synthesis, Spectroscopy, Photophysics, and in vitro Photosensitizing Efficacy ChemMedChem ·J. Da̧browski, Luı́s G. Arnaut, Mariette M. Pereira, Carlos J. P. Monteiro, Krystyna Urbańska, Sérgio Simões, Grażyna Stochel	2010	95
19	Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment Molecular Therapy — Nucleic Acids ·Pedro M. Costa, Ana L. Cardoso, Liliana Mendonça, Angelo Serani, Carlos Custódia, Mariana Conceição, Sérgio Simões, João Nuno Moreira, Luís Pereira de Almeida, Maria C. Pedroso de Lima	2013	93
20	Combined effects of singlet oxygen and hydroxyl radical in photodynamic therapy with photostable bacteriochlorins: Evidence from intracellular fluorescence and increased photodynamic efficacy in vitro Free Radical Biology and Medicine ·J. Da̧browski, Luı́s G. Arnaut, Mariette M. Pereira, Krystyna Urbańska, Sérgio Simões, Grażyna Stochel, Luísa Cortes	2012	80

About Sérgio Simões

Sérgio Simões is a scholar working on Molecular Biology, Genetics, Biomaterials, Biomedical Engineering and Pharmaceutical Science, having authored 152 papers that have together received 7.3k indexed citations. Recurring topics across this work include RNA Interference and Gene Delivery (69 papers), Advanced biosensing and bioanalysis techniques (50 papers), Virus-based gene therapy research (29 papers), Drug Solubulity and Delivery Systems (15 papers), Nanoparticle-Based Drug Delivery (14 papers), Nanoplatforms for cancer theranostics (13 papers), Photodynamic Therapy Research Studies (10 papers) and DNA and Nucleic Acid Chemistry (9 papers). The work is most often cited by research in Pharmaceutical Science (969 citations), Biomaterials (1.7k citations), Molecular Biology (4.4k citations), Genetics (1.0k citations) and Biomedical Engineering (1.5k citations). Sérgio Simões has collaborated with scholars based in Portugal, United States and Poland. Frequent co-authors include Maria C. Pedroso de Lima, Nejat Düzgüneş, Rogério Gaspar, João Nuno Moreira, Cristina Fonseca, Vladimir Slepushkin, Cláudia Silva, Henrique Faneca, Pedro Pires and Jorge F. J. Coelho. Their work appears in journals such as Journal of Controlled Release, Biochimica et Biophysica Acta (BBA) - Biomembranes, International Journal of Pharmaceutics, European Journal of Pharmaceutics and Biopharmaceutics and Molecular Membrane Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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