Sérgio Simões

9.2k total citations · 1 hit paper
152 papers, 7.3k citations indexed

About

Sérgio Simões is a scholar working on Molecular Biology, Genetics and Biomaterials. According to data from OpenAlex, Sérgio Simões has authored 152 papers receiving a total of 7.3k indexed citations (citations by other indexed papers that have themselves been cited), including 92 papers in Molecular Biology, 29 papers in Genetics and 21 papers in Biomaterials. Recurrent topics in Sérgio Simões's work include RNA Interference and Gene Delivery (69 papers), Advanced biosensing and bioanalysis techniques (50 papers) and Virus-based gene therapy research (29 papers). Sérgio Simões is often cited by papers focused on RNA Interference and Gene Delivery (69 papers), Advanced biosensing and bioanalysis techniques (50 papers) and Virus-based gene therapy research (29 papers). Sérgio Simões collaborates with scholars based in Portugal, United States and Poland. Sérgio Simões's co-authors include Maria C. Pedroso de Lima, Nejat Düzgüneş, Rogério Gaspar, João Nuno Moreira, Cristina Fonseca, Vladimir Slepushkin, Cláudia Silva, Henrique Faneca, Pedro Pires and Jorge F. J. Coelho and has published in prestigious journals such as Journal of Biological Chemistry, Accounts of Chemical Research and PLoS ONE.

In The Last Decade

Sérgio Simões

151 papers receiving 7.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity

2002 581 citations Sérgio Simões, Rogério Gaspar et al. Journal of Controlled Release profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sérgio Simões Portugal	48	4.4k	1.7k	1.5k	1.0k	969	152	7.3k
Hu‐Lin Jiang China	46	3.0k 0.7×	1.8k 1.0×	2.2k 1.4×	755 0.7×	474 0.5×	195	6.7k
Udo Bakowsky Germany	57	5.0k 1.1×	2.5k 1.5×	2.2k 1.4×	947 0.9×	1.6k 1.7×	241	10.0k
Gaurav Sahay United States	37	5.7k 1.3×	2.1k 1.2×	1.8k 1.2×	784 0.8×	496 0.5×	69	8.4k
Youngro Byun South Korea	49	3.2k 0.7×	2.1k 1.3×	1.6k 1.1×	529 0.5×	1.2k 1.2×	261	7.8k
Shigeru Kawakami Japan	50	4.7k 1.1×	1.4k 0.8×	1.3k 0.9×	1.1k 1.1×	540 0.6×	221	6.9k
Joanna Rejman Belgium	34	3.7k 0.8×	2.1k 1.2×	1.7k 1.1×	768 0.7×	456 0.5×	63	6.9k
Crispin R. Dass Australia	54	5.7k 1.3×	2.3k 1.4×	1.8k 1.2×	682 0.7×	1.2k 1.2×	223	11.5k
Dominik Witzigmann Canada	31	6.2k 1.4×	2.3k 1.4×	2.0k 1.3×	754 0.7×	538 0.6×	64	9.1k
In‐Kyu Park South Korea	49	2.7k 0.6×	2.8k 1.6×	2.3k 1.5×	633 0.6×	603 0.6×	196	7.1k
Robbert J. Kok Netherlands	44	3.0k 0.7×	1.7k 1.0×	1.2k 0.8×	382 0.4×	614 0.6×	136	6.4k

Countries citing papers authored by Sérgio Simões

Since Specialization

Citations

This map shows the geographic impact of Sérgio Simões's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sérgio Simões with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sérgio Simões more than expected).

Fields of papers citing papers by Sérgio Simões

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sérgio Simões. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sérgio Simões. The network helps show where Sérgio Simões may publish in the future.

Co-authorship network of co-authors of Sérgio Simões

This figure shows the co-authorship network connecting the top 25 collaborators of Sérgio Simões. A scholar is included among the top collaborators of Sérgio Simões based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sérgio Simões. Sérgio Simões is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Lopes, Diana, Carolina Henriques, António Nunes, et al.. (2025). Integrating microfluidics and streamlined remote drug loading: one step closer to continuous manufacturing of liposomal injectables containing small drugs. International Journal of Pharmaceutics. 682. 125973–125973.

Fonseca, Nuno A., et al.. (2025). Bridging membrane fluidity studies with a predictive model of drug encapsulation to address industrial challenges of liposomal injectables manufacturing. Drug Delivery and Translational Research. 15(9). 3281–3295. 2 indexed citations

Simões, Sérgio, et al.. (2024). Oromucosal spray products – Viscosity impact on spray performance evaluation. Journal of Drug Delivery Science and Technology. 94. 105480–105480. 1 indexed citations

Simões, Sérgio, et al.. (2024). A review on the scale-up of high-shear wet granulation processes and the impact of process parameters. Particuology. 92. 180–195. 3 indexed citations

Vitorino, Carla, et al.. (2023). Development of a buccal in vitro permeation method – exploring aQbD implementation. International Journal of Pharmaceutics. 643. 123255–123255. 3 indexed citations

Simões, Sérgio, et al.. (2022). Oromucosal products – Market landscape and innovative technologies: A review. Journal of Controlled Release. 348. 305–320. 19 indexed citations

Fonseca, Nuno A., Nélio Gonçalves, Ana C. Gregório, et al.. (2022). Nucleolin Overexpression Predicts Patient Prognosis While Providing a Framework for Targeted Therapeutic Intervention in Lung Cancer. Cancers. 14(9). 2217–2217. 8 indexed citations

Simões, Sérgio, et al.. (2022). Regulatory Science Approach in Pharmaceutical Development of Follow-on Versions of Non-Biological Complex Drug Products. Journal of Pharmaceutical Sciences. 111(10). 2687–2713. 12 indexed citations

Silva, Cláudia, et al.. (2022). A quality by design (QbD) approach in pharmaceutical development of lipid-based nanosystems: A systematic review. Journal of Drug Delivery Science and Technology. 70. 103207–103207. 26 indexed citations

10.

Palmeira‐de‐Oliveira, Rita, et al.. (2022). Women’s preferences and acceptance for different drug delivery routes and products. Advanced Drug Delivery Reviews. 182. 114133–114133. 17 indexed citations

11.

Silva, Cláudia, et al.. (2019). Quality by design in pharmaceutical manufacturing: A systematic review of current status, challenges and future perspectives. European Journal of Pharmaceutics and Biopharmaceutics. 147. 19–37. 167 indexed citations

12.

Rocha, Luís B., Fábio A. Schaberle, J. Da̧browski, Sérgio Simões, & Luı́s G. Arnaut. (2015). Intravenous Single-Dose Toxicity of Redaporfin-Based Photodynamic Therapy in Rodents. International Journal of Molecular Sciences. 16(12). 29236–29249. 30 indexed citations

13.

Gomes‐da‐Silva, Lígia C., Adriana O. Santos, Luís M. Bimbo, et al.. (2012). Toward a siRNA-containing nanoparticle targeted to breast cancer cells and the tumor microenvironment. International Journal of Pharmaceutics. 434(1-2). 9–19. 39 indexed citations

14.

Santos, Adriana O., et al.. (2010). In vitro modulation of Bcl-2 levels in small cell lung cancer cells: effects on cell viability. Brazilian Journal of Medical and Biological Research. 43(10). 1001–1009. 4 indexed citations

15.

Moreira, João Nuno, Adriana O. Santos, & Sérgio Simões. (2006). Bcl-2-Targeted Antisense Therapy (Oblimersen Sodium): Towards Clinical Reality. Reviews on Recent Clinical Trials. 1(3). 217–235. 37 indexed citations

16.

Cruz, M. Teresa Girão da, Ana L. Cardoso, Luís Pereira de Almeida, Sérgio Simões, & Maria C. Pedroso de Lima. (2005). Tf-lipoplex-mediated NGF gene transfer to the CNS: neuronal protection and recovery in an excitotoxic model of brain injury. Gene Therapy. 12(16). 1242–1252. 50 indexed citations

17.

Lima, Maria C. Pedroso de, et al.. (2003). Cationic Liposomes for Gene Delivery: From Biophysics to Biological Applications. Current Medicinal Chemistry. 10(14). 1221–1231. 125 indexed citations

18.

Simões, Sérgio, et al.. (2002). Protein-associated lipoplexes: Novel strategies to enhance gene delivery mediated by lipid-based particles. Scholarly Commons (University of the Pacific). 12(6). 339–344. 3 indexed citations

19.

Lima, Maria C. Pedroso de, et al.. (1999). Gene delivery mediated by cationic liposomes: from biophysical aspects to enhancement of transfection. Molecular Membrane Biology. 16(1). 103–109. 65 indexed citations

20.

Simões, Sérgio, Vladimir Slepushkin, Rogério Gaspar, Maria C. Pedroso de Lima, & Nejat Düzgüneş. (1997). Enhancement of cationic liposome-mediated gene delivery by transferrin and fusogenic peptides. Scholarly Commons (University of the Pacific). 659. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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