Sandra Villegas

3.3k total citations · 1 hit paper
91 papers, 2.7k citations indexed

About

Sandra Villegas is a scholar working on Molecular Biology, Physiology and Oncology. According to data from OpenAlex, Sandra Villegas has authored 91 papers receiving a total of 2.7k indexed citations (citations by other indexed papers that have themselves been cited), including 40 papers in Molecular Biology, 26 papers in Physiology and 15 papers in Oncology. Recurrent topics in Sandra Villegas's work include Alzheimer's disease research and treatments (26 papers), Chemical Synthesis and Characterization (13 papers) and Radioactive element chemistry and processing (12 papers). Sandra Villegas is often cited by papers focused on Alzheimer's disease research and treatments (26 papers), Chemical Synthesis and Characterization (13 papers) and Radioactive element chemistry and processing (12 papers). Sandra Villegas collaborates with scholars based in Spain, Chile and Germany. Sandra Villegas's co-authors include Francesc Avilés, Laia Montoliu‐Gaya, Gisela Esquerda-Canals, Bernabé L. Rivas, Luís Serrano, José Luís Sánchez-Quesada, José C. Martínez, H. A. Maturana, Jordi Ordóñez‐Llanos and Ana Rosa Viguera and has published in prestigious journals such as Journal of Biological Chemistry, PLoS ONE and Journal of Molecular Biology.

In The Last Decade

Sandra Villegas

91 papers receiving 2.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Amyloid-beta peptide and tau protein crosstalk in Alzheimer’s disease

2021 183 citations Sandra Villegas, Laia Montoliu‐Gaya et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sandra Villegas Spain	29	1.3k	740	396	248	222	91	2.7k
Susanne Mohr United States	32	1.8k 1.4×	675 0.9×	333 0.8×	341 1.4×	146 0.7×	71	4.0k
Hongwei Jin China	36	2.2k 1.7×	417 0.6×	298 0.8×	327 1.3×	320 1.4×	222	5.5k
Nicola Traverso Italy	33	1.6k 1.3×	581 0.8×	153 0.4×	120 0.5×	270 1.2×	80	3.5k
Susana Cardoso Portugal	26	1.2k 0.9×	924 1.2×	152 0.4×	301 1.2×	275 1.2×	48	3.0k
Francesca Re Italy	36	1.6k 1.3×	1.1k 1.5×	437 1.1×	277 1.1×	541 2.4×	123	4.2k
Elena Obrador Spain	33	1.9k 1.5×	368 0.5×	254 0.6×	131 0.5×	431 1.9×	60	3.8k
Yusei Miyamoto Japan	36	1.2k 0.9×	471 0.6×	781 2.0×	220 0.9×	519 2.3×	82	4.1k
Cinzia Domenicotti Italy	33	2.3k 1.8×	574 0.8×	181 0.5×	133 0.5×	368 1.7×	106	4.1k
Renato X. Santos Portugal	28	1.4k 1.1×	1.2k 1.7×	174 0.4×	369 1.5×	274 1.2×	44	3.5k
Daret St. Clair United States	21	1.5k 1.2×	452 0.6×	138 0.3×	215 0.9×	470 2.1×	51	2.8k

Countries citing papers authored by Sandra Villegas

Since Specialization

Citations

This map shows the geographic impact of Sandra Villegas's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sandra Villegas with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sandra Villegas more than expected).

Fields of papers citing papers by Sandra Villegas

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sandra Villegas. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sandra Villegas. The network helps show where Sandra Villegas may publish in the future.

Co-authorship network of co-authors of Sandra Villegas

This figure shows the co-authorship network connecting the top 25 collaborators of Sandra Villegas. A scholar is included among the top collaborators of Sandra Villegas based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sandra Villegas. Sandra Villegas is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Montoliu‐Gaya, Laia, et al.. (2018). Aβ-oligomer uptake and the resulting inflammatory response in adult human astrocytes are precluded by an anti-Aβ single chain variable fragment in combination with an apoE mimetic peptide. Molecular and Cellular Neuroscience. 89. 49–59. 24 indexed citations

Montoliu‐Gaya, Laia, et al.. (2018). Differential effects of apoE and apoJ mimetic peptides on the action of an anti-Aβ scFv in 3xTg-AD mice. Biochemical Pharmacology. 155. 380–392. 19 indexed citations

Montoliu‐Gaya, Laia, Sandra D. Mulder, Robert Veerhuis, & Sandra Villegas. (2017). Effects of an Aβ-antibody fragment on Aβ aggregation and astrocytic uptake are modulated by apolipoprotein E and J mimetic peptides. PLoS ONE. 12(11). e0188191–e0188191. 13 indexed citations

Murciano‐Calles, Javier, et al.. (2016). Common features in the unfolding and misfolding of PDZ domains and beyond: the modulatory effect of domain swapping and extra-elements. Scientific Reports. 6(1). 19242–19242. 9 indexed citations

Montoliu‐Gaya, Laia & Sandra Villegas. (2015). Protein structures in Alzheimer's disease: The basis for rationale therapeutic design. Archives of Biochemistry and Biophysics. 588. 1–14. 12 indexed citations

Giménez‐Llort, Lydia, et al.. (2013). Early intervention in the 3xTg-AD mice with an amyloid β-antibody fragment ameliorates first hallmarks of Alzheimer disease. mAbs. 5(5). 665–864. 51 indexed citations

Marin‐Argany, Marta, et al.. (2013). Elongation of the C-terminal domain of an anti-amyloid β single-chain variable fragment increases its thermodynamic stability and decreases its aggregation tendency. mAbs. 5(5). 678–689. 16 indexed citations

Sánchez-Quesada, José Luís, Sandra Villegas, & Jordi Ordóñez‐Llanos. (2012). Electronegative low-density lipoprotein. A link between apolipoprotein B misfolding, lipoprotein aggregation and proteoglycan binding. Current Opinion in Lipidology. 23(5). 479–486. 42 indexed citations

Martı́, Joaquı́n, et al.. (2012). Principal Component and Cluster Analysis of Morphological Variables Reveals Multiple Discrete Sub-phenotypes in Weaver Mouse Mutants. The Cerebellum. 12(3). 406–417. 5 indexed citations

10.

Cerdà‐Costa, Núria, Jaume Bonet, M. Rosario Fernández, et al.. (2010). Prediction of a new class of RNA recognition motif. Journal of Molecular Modeling. 17(8). 1863–1875. 1 indexed citations

11.

Bancells, Cristina, Sandra Villegas, Francisco J. Blanco, et al.. (2010). Aggregated Electronegative Low Density Lipoprotein in Human Plasma Shows a High Tendency toward Phospholipolysis and Particle Fusion. Journal of Biological Chemistry. 285(42). 32425–32435. 45 indexed citations

12.

Cerdà‐Costa, Núria, Alexandra Esteras‐Chopo, Francesc Avilés, Luís Serrano, & Sandra Villegas. (2006). Early Kinetics of Amyloid Fibril Formation Reveals Conformational Reorganisation of Initial Aggregates. Journal of Molecular Biology. 366(4). 1351–1363. 55 indexed citations

13.

Villegas, Sandra, José C. Martínez, Nico A. J. van Nuland, et al.. (2000). Thermodynamic analysis of helix‐engineered forms of the activation domain of human procarboxypeptidase A2. European Journal of Biochemistry. 267(19). 5891–5899. 11 indexed citations

14.

Villegas, Sandra, Jesús Zurdo, Vladimir V. Filimonov, et al.. (2000). Protein engineering as a strategy to avoid formation of amyloid fibrils. Protein Science. 9(9). 1700–1708. 100 indexed citations

15.

Ventura, Salvador, Sandra Villegas, Jeffrey Larson, et al.. (1999). Mapping the Pro-region of Carboxypeptidase B by Protein Engineering. Journal of Biological Chemistry. 274(28). 19925–19933. 42 indexed citations

16.

Reverter, David, Salvador Ventura, Sandra Villegas, Josep Vendrell, & Francesc Avilés. (1998). Overexpression of Human Procarboxypeptidase A2 in Pichia pastoris and Detailed Characterization of Its Activation Pathway. Journal of Biological Chemistry. 273(6). 3535–3541. 46 indexed citations

17.

Viguera, Ana Rosa, Sandra Villegas, Francesc Avilés, & Luis Serrano. (1997). Favourable native-like helical local interactions can accelerate protein folding. PubMed. 2(1). 23–33. 85 indexed citations

18.

Villegas, Sandra, Ana Rosa Viguera, Francesc Avilés, & L. Serrano. (1996). Stabilization of proteins by rational design of α-helix stability using helix/coil transition theory. PubMed. 1(1). 29–34. 80 indexed citations

19.

Villegas, Sandra, Josep Vendrell, & Francesc Avilés. (1995). The activation pathway of procarboxypeptidase B from porcine pancreas: Participation of the active enzyme in the proteolytic processing. Protein Science. 4(9). 1792–1800. 21 indexed citations

20.

Villegas, Sandra, et al.. (1991). Analysis of the activation process of porcine procarboxypeptidase B and determination of the sequence of its activation segment. Biochemistry. 30(16). 4082–4089. 40 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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