Sandra Close

6.9k citations

39 papers · 4.7k indexed · 5 hit papers · h-index 17

Impact in

Internal Medicine top 0.5%
- Venous Thromboembolism Diagnosis and Management
Cardiology and Cardiovascular Medicine top 0.5%
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research

Papers in ⓘ

Pharmacology 9
- Pharmacogenetics and Drug Metabolism 9
- Inflammatory mediators and NSAID effects 3
Cardiology and Cardiovascular Medicine 16
- Antiplatelet Therapy and Cardiovascular Diseases 15

Co-authors: Jessica L. Mega (8 shared papers)Stephen D. Wiviott (8 shared papers)Marc S. Sabatine (8 shared papers)Elliott M. Antman (7 shared papers)John T. Brandt (5 shared papers)Joseph R. Walker (7 shared papers)Eugene Braunwald (4 shared papers)Richard D. Hockett (7 shared papers)
Journals: Blood (7 papers)Circulation (3 papers)Journal of Clinical Oncology (3 papers)The Pharmacogenomics Journal (2 papers)The Lancet (2 papers)
Partner nations: United States South Korea Germany

In The Last Decade

Sandra Close

36 papers receiving 4.6k citations

Hit Papers

5 papers align trajectories log scale

Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON–TIMI 38 trial: a pharmacogenetic analysis 2010 · 437 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2010 The Lancet
2009 Circulation
2009 The Lancet
2008 New England Journal of Medicine
2007 Journal of Thrombosis and Haemostasis

Peers

Countries citing papers authored by Sandra Close

Since Specialization

Citations

This map shows the geographic impact of Sandra Close's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sandra Close with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sandra Close more than expected).

Fields of papers citing papers by Sandra Close

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sandra Close. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sandra Close. The network helps show where Sandra Close may publish in the future.

Co-authors

The 25 scholars most cited alongside Sandra Close, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Sandra Close Line = papers co-authored together Sandra Close links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 39 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Cytochrome P-450 Polymorphisms and Response to Clopidogrel New England Journal of Medicine ·Jessica L. Mega, Sandra Close, Stephen D. Wiviott, Lei Shen, Richard D. Hockett, John T. Brandt, Joseph R. Walker, Elliott M. Antman, William L. Macias, Eugene Braunwald, Marc S. Sabatine Hit paper breakdown →	2008	1725
2	Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel Journal of Thrombosis and Haemostasis ·John T. Brandt, Sandra Close, Stephen J. Iturria, Christopher D. Payne, Nazar Farid, C. Steven Ernest, D. Richard Lachno, Daniel E. Salazar, Kenneth J. Winters Hit paper breakdown →	2007	553
3	Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials The Lancet ·Michelle L. O’Donoghue, Eugene Braunwald, Elliott M. Antman, Sabina A. Murphy, Eric Bates, Yoseph Rozenman, Alan D. Michelson, Raymond W.M. Hautvast, Peter N Ver Lee, Sandra Close, Lei Shen, Jessica L. Mega, Marc S. Sabatine, Stephen D. Wiviott Hit paper breakdown →	2009	500
4	Cytochrome P450 Genetic Polymorphisms and the Response to Prasugrel Circulation ·Jessica L. Mega, Sandra Close, Stephen D. Wiviott, Lei Shen, Richard D. Hockett, John T. Brandt, Joseph R. Walker, Elliott M. Antman, William L. Macias, Eugene Braunwald, Marc S. Sabatine Hit paper breakdown →	2009	467
5	Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON–TIMI 38 trial: a pharmacogenetic analysis The Lancet ·Jessica L. Mega, Sandra Close, Stephen D. Wiviott, Lei Shen, Joseph R. Walker, Tabassome Simon, Elliott M. Antman, Eugene Braunwald, Marc S. Sabatine Hit paper breakdown →	2010	437
6	Genomewide association for schizophrenia in the CATIE study: results of stage 1 Molecular Psychiatry ·Patrick F. Sullivan, D. Y. Lin, J.‐W. Tzeng, Edwin van den Oord, Diana O. Perkins, T. Scott Stroup, Michael J. Wagner, Seonjoo Lee, Fred A. Wright, Fei Zou, W. Xu F.C. Liu, AnnCatherine M. Downing, Jeffrey A. Lieberman, Sandra Close	2008	265
7	Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease European Heart Journal ·Christoph Varenhorst, Stefan James, David Erlinge, John T. Brandt, Oscar Ö. Braun, M. Man, Agneta Siegbahn, Judith S. Walker, Lars Wallentin, Kenneth J. Winters, Sandra Close	2009	191
8	Genetic Variation in Metabolizing Enzyme and Transporter Genes: Comprehensive Assessment in 3 Major East Asian Subpopulations With Comparison to Caucasians and Africans The Journal of Clinical Pharmacology ·Michael Man, Mark W. Farmen, Carmen M. Dumaual, Choo Hua Teng, Brian A. Moser, Shin Irie, Gyu Jeong Noh, Reuben Njau, Sandra Close, Stephen D. Wise, Richard D. Hockett	2010	170
9	A Haplotype of the Norepinephrine Transporter (Net) Gene Slc6a2 is Associated with Clinical Response to Atomoxetine in Attention-Deficit Hyperactivity Disorder (ADHD) Neuropsychopharmacology ·Nicolás Ramoz, Claudette Boni, AnnCatherine M. Downing, Sandra Close, Sandra L Peters, Angela M Prokop, Albert J. Allen, M. Hamon, Diane Purper‐Ouakil, Philip Gorwood	2009	43
10	Clinical Utility of Liquid Diagnostic Platforms in Non-Small Cell Lung Cancer The Oncologist ·Benjamin Levy, Zishuo I. Hu, Kristen N. Cordova, Sandra Close, Karen Lee, Daniel Becker	2016	43
11	Multiplex Assay for Comprehensive Genotyping of Genes Involved in Drug Metabolism, Excretion, and Transport Clinical Chemistry ·Thomas M. Daly, Carmen M. Dumaual, Xin Miao, Mark W. Farmen, Reuben Njau, Dong‐Jing Fu, N L Bauer, Sandra Close, Nancy Watanabe, Carsten Bruckner, Paul Hardenbol, Richard D. Hockett	2007	43
12	Pharmacokinetics and pharmacodynamics following maintenance doses of prasugrel and clopidogrel in Chinese carriers of CYP2C19 variants British Journal of Clinical Pharmacology ·Ronan P. Kelly, Sandra Close, Nagy A. Farid, Kenneth J. Winters, Lei Shen, Fanni Natanegara, Joseph A. Jakubowski, Mary Ho, Joseph R. Walker, David S. Small	2011	42
13	A Randomized Phase 2 Study Comparing the Combination of Ficlatuzumab and Gefitinib with Gefitinib Alone in Asian Patients with Advanced Stage Pulmonary Adenocarcinoma Journal of Thoracic Oncology ·Tony Mok, Sarayut Lucien Geater, Wu‐Chou Su, Eng-Huat Tan, James Chih‐Hsin Yang, Gee‐Chen Chang, May Han, Philip Komarnitsky, Francis Payumo, Jennifer Garrus, Sandra Close, Keunchil Park	2016	41
14	Dopamine receptor D3 genotype association with greater acute positive symptom remission with olanzapine therapy in predominately caucasian patients with chronic schizophrenia or schizoaffective disorder Human Psychopharmacology Clinical and Experimental ·David H. Adams, Sandra Close, Mark W. Farmen, AnnCatherine M. Downing, Alan Breier, John P. Houston	2008	31
15	Beyond single-marker analyses: mining whole genome scans for insights into treatment responses in severe sepsis The Pharmacogenomics Journal ·M. Man, Sandra Close, Andrew Shaw, Gordon R. Bernard, Ivor S. Douglas, R.J. Kaner, Didier Payen, Jean‐Louis Vincent, Stewart Fossceco, Jonathan Janes, Amy G Leishman, Lee A. O’Brien, Mark D. Williams, Joe G. N. Garcia	2012	27
16	PON1 Q192R genetic variant and response to clopidogrel and prasugrel: pharmacokinetics, pharmacodynamics, and a meta-analysis of clinical outcomes Journal of Thrombosis and Thrombolysis ·Jessica L. Mega, Sandra Close, Stephen D. Wiviott, Michael Man, Suman Duvvuru, Joseph R. Walker, Scott S. Sundseth, Jean-Philippe Collet, Jessica Delaney, Jean‐Sébastien Hulot, Sabina A. Murphy, Guillaume Paré, Matthew J. Price, Dirk Sibbing, Tabassome Simon, Dietmar Trenk, Elliott M. Antman, Marc S. Sabatine	2015	22
17	Audit of opioid prescribing: the effect of hospital guidelines Anaesthesia ·Claire Humphries, David Counsell, Ramon Pediani, Sandra Close	1997	17
18	Pharmacogenetics and pharmacogenomics of thienopyridines: clinically relevant? Fundamental and Clinical Pharmacology ·Sandra Close	2011	14
19	Designing pharmacogenetic projects in industry: practical design perspectives from the Industry Pharmacogenomics Working Group The Pharmacogenomics Journal ·Christina M. Bromley, Sandra Close, Nadine Cohen, Reyna Favis, Bonnie A. Fijal, Ferdous Gheyas, W Liu, Catalina López-Correa, A. Prokop, J B Singer, Amir Snapir, A. Tchelet, D Wang, Dan Goldstaub	2008	14
20	Clopidogrel pharmacogenetics: metabolism and drug interactions Drug metabolism and drug interactions ·Sandra Close	2011	13

About Sandra Close

Sandra Close is a scholar working on Pharmacology, Cardiology and Cardiovascular Medicine, Cancer Research, Internal Medicine and Oncology, having authored 39 papers that have together received 4.7k indexed citations. Recurring topics across this work include Antiplatelet Therapy and Cardiovascular Diseases (15 papers), Cancer Genomics and Diagnostics (10 papers), Lipoproteins and Cardiovascular Health (10 papers), Pharmacogenetics and Drug Metabolism (9 papers), Lymphoma Diagnosis and Treatment (7 papers), Diabetes Treatment and Management (5 papers), Lung Cancer Treatments and Mutations (5 papers) and Inflammatory mediators and NSAID effects (3 papers). The work is most often cited by research in Internal Medicine (775 citations), Cardiology and Cardiovascular Medicine (3.5k citations), Pharmacology (618 citations), Endocrinology, Diabetes and Metabolism (980 citations) and Pharmacology (931 citations). Sandra Close has collaborated with scholars based in United States, South Korea and Germany. Frequent co-authors include Jessica L. Mega, Stephen D. Wiviott, Marc S. Sabatine, Elliott M. Antman, John T. Brandt, Joseph R. Walker, Eugene Braunwald, Richard D. Hockett, William L. Macias and Lei Shen. Their work appears in journals such as Blood, Circulation, Journal of Clinical Oncology, The Pharmacogenomics Journal and The Lancet.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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