S Hirohashi

10.3k citations

133 papers · 8.7k indexed · 2 hit papers · h-index 51

Impact in

Hepatology top 0.5%
- Hepatocellular Carcinoma Treatment and Prognosis
Oncology top 1%
- Cancer-related Molecular Pathways
- Pancreatic and Hepatic Oncology Research

Papers in

Hepatology 15
- Hepatocellular Carcinoma Treatment and Prognosis 15
Oncology 36
- Cancer-related Molecular Pathways 12

Co-authors: Y Shimoyama Yae Kanai Yukío Shimosato Atsushi Ochiai T Sugimura Michiie Sakamoto Kenta Yoshiura Masatoshi Takeichi
Journals: Japanese Journal of Clinical Oncology (10 papers)British Journal of Cancer (9 papers)Biochemical and Biophysical Research Communications (6 papers)Radiology (4 papers)Proceedings of the National Academy of Sciences (4 papers)
Partner nations: Japan United Kingdom United States

In The Last Decade

S Hirohashi

131 papers receiving 8.4k citations

Hit Papers

align trajectories log scale

Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. 1995 · 546 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1995 Proceedings of the National Academy of Sciences
1989 PubMed

Peers

Countries citing papers authored by S Hirohashi

Since Specialization

Citations

This map shows the geographic impact of S Hirohashi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by S Hirohashi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites S Hirohashi more than expected).

Fields of papers citing papers by S Hirohashi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by S Hirohashi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by S Hirohashi. The network helps show where S Hirohashi may publish in the future.

Co-authorship network

The 25 scholars most cited alongside S Hirohashi, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with S Hirohashi Line = papers co-authored together S Hirohashi links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state Carcinogenesis ·Yae Kanai, S Hirohashi	2007	177
2	Involvement of dysadherin and E-cadherin in the development of testicular tumours British Journal of Cancer ·Anna Batistatou, Chrisoula D. Scopa, P. Ravazoula, Yukihiro Nakanishi, Dimitrios Peschos, Niki J. Agnantis, S Hirohashi, Alexandros Charalabopoulos	2005	27
3	Regulation of DNaseY activity by actinin-α4 during apoptosis Cell Death and Differentiation ·Gabriella Mirabile, Joy X Lei, Julie Leblanc, Caroline Sodja, Sanskriti Bhardwaj, 黄龙铉, P. Roy Walker, Tetsuya Yamada, S Hirohashi, M. Sikorska	2004	23
4	Expression of enamel proteins and LEF1 in adamantinomatous craniopharyngioma: evidence for its odontogenic epithelial differentiation Histopathology ·Shigeki Sekine, Takashi Takata, Tatsuhiro Shibata, Masaya Mori, Y Morishita, Masayuki Noguchi, Takashi Uchida, Yae Kanai, S Hirohashi	2004	56
5	Aberrant O-glycosylation inhibits stable expression of dysadherin, a carcinoma-associated antigen, and facilitates cell-cell adhesion Glycobiology ·Hitomi Tsuiji, S. Takasaki, Michiie Sakamoto, T Irimura, S Hirohashi	2003	49
6	Population-based genetic alterations in Ewing’s tumors from Japanese and European Caucasian patients Annals of Oncology ·Toshifumi Ozaki, Karl‐Ludwig Schaefer, Daniel Wai, Stephanie Frank, S. Ahrens, Raihanatou Diallo, Amosova Li, Tadakazu Shimoda, S Hirohashi, Akira Kawai, Noriko Naito, Yuki Morimoto, H. Inoue, Werner Boecker, Heribert Juergens, Winfried Winkelmann, Barbara Dockhorn‐Dworniczak, Christopher Poremba	2002	24
7	[Recent progress in study of mechanism of invasion and metastasis of hepatocellular carcinoma]. PubMed ·Masaaki Takamura, Michiie Sakamoto, S Hirohashi	2001	1
8	Molecular aspects of adhesion-epigenetic mechanisms for inactivation of the E-Cadherin-mediated cell adhesion system in cancers. PubMed ·S Hirohashi	2000	12
9	[Dysfunction of E-cadherin-catenin system in invasion and metastasis of colorectal cancer]. PubMed ·Keiji Maruyama, A. Ochiai, Shinji Nakamura, Paul Krueper, S Hirohashi	1998	5
10	Report of the Eleventh International Symposium of the Foundation for Promotion of Cancer Research: Basic and Clinical Research in Gastric Cancer Japanese Journal of Clinical Oncology ·Mitsuru Sasako, G. Bruce Mann, Cornelis J.�H. van de Velde, S Hirohashi, Shigeo Yoshida	1998	5
11	Analysis of Loss of Heterozygosity in Small Adenocarcinomas of the Lung Japanese Journal of Clinical Oncology ·寿人長谷川, Sun Zeng-zhen, Yoshihiro Matsuno, Takuro Yamada, Yukío Shimosato, S Hirohashi, Masayuki Noguchi	1998	10
12	Prognostic Indicators for Breast Cancer Patients With One to Three Regional Lymph Node Metastases, With Special Reference to Alterations in Expression Levels of bcl-2, p53 and c-erbB-2 Proteins Japanese Journal of Clinical Oncology ·A. Ozpineci, Hidetoshi Tsuda, L. S. Hovsepyan, Toshiaki Fukutomi, Hiroshi Yamamoto, S Hirohashi	1997	35
13	Frequent Occurrence of c-Ki-ras Gene Mutations in Well Differentiated Endometrial Adenocarcinoma Showing Infiltrative Local Growth with Fibrosing Stromal Response International Journal of Gynecological Pathology ·Hiroshi Tsuda, Gabriel Nojosa Oliveira, Taranveer Singh, Takahiko Yamada, K. Tanemura, Ryosuke Tsunematsu, K. Ohmi, Takao Sonoda, S Hirohashi	1995	17
14	British Stomach Cancer Group Gut ·Peter McCulloch, Atsushi Ochiai, 弘金丸, Jennifer Nash, Mitsuru Sasako, S Hirohashi, Neil Keeling, J.I. Livingstone, BARLA‐SZABÓ JENö, C Wastell	1994	1
15	Abnormalities of cell adhesion molecules in multistage carcinogenesis Yoshiakira Kanai, Y Shimoyama, Tatsuya Oda, S Hirohashi	1994	2
16	Early advanced hepatocellular carcinoma: evaluation of CT and MR appearance with pathologic correlation. Radiology ·Thomas C. Winter, Kenichi Takayasu, Y Muramatsu, H. Furukawa, Fumihiko Wakao, W. Lohmann, Shiran Chamika, S Hirohashi, Patrick C. Freeny	1994	95
17	Segmental transarterial chemoembolization with lipiodol mixed with anticancer drugs for nonresectable hepatocellular carcinoma: follow-up CT and therapeutic results Cancer Chemotherapy and Pharmacology ·K Nishimine, Hideo Uchida, Naoki Matsuo, Haitian Zhou, S Hirohashi, Y Nishimura, Qiyong Guo, Hajime Ohishi, Mark Buchner, Tetsuya Yoshioka, S Ohue, Hiroshi Fukui, Jessica Planelles-Villalva	1994	56
18	Possible role of activated ras genes in human esophageal carcinogenesis International Journal of Cancer ·Г. В. Бабушкина, Alfredo Fusco, N. Martel, Coopérative des Avirons Reu, S Hirohashi, Hiroshi Yamasaki	1993	10
19	Cloning of the Human α-Catenin cDNA and Its Aberrant mRNA in a Human Cancer Cell Line Biochemical and Biophysical Research Communications ·Tatsuya Oda, Yoshiakira Kanai, Y Shimoyama, Akira Nagafuchi, Shöichiro Tsukita, S Hirohashi	1993	77
20	Hormone dependency of a serially transplantable human breast cancer (Br-10) in nude mice. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·S Hirohashi, Yukío Shimosato, Toru Kameya, Kanji Nagai, Ryuichiro Tsunematsu	1977	28

About S Hirohashi

S Hirohashi is a scholar working on Hepatology, Oncology, Cancer Research, Molecular Biology and Radiology, Nuclear Medicine and Imaging, having authored 133 papers that have together received 8.7k indexed citations. Recurring topics across this work include Wnt/β-catenin signaling in development and cancer (23 papers), Cancer-related gene regulation (20 papers), Hepatocellular Carcinoma Treatment and Prognosis (15 papers), Cancer-related Molecular Pathways (12 papers), Glycosylation and Glycoproteins Research (11 papers), Monoclonal and Polyclonal Antibodies Research (11 papers), Cholangiocarcinoma and Gallbladder Cancer Studies (10 papers) and RNA modifications and cancer (9 papers). The work is most often cited by research in Hepatology (1.1k citations), Oncology (2.7k citations), Immunology and Allergy (472 citations), Cancer Research (1.1k citations) and Molecular Biology (4.6k citations). S Hirohashi has collaborated with scholars based in Japan, United Kingdom and United States. Frequent co-authors include Y Shimoyama, Yae Kanai, Yukío Shimosato, Atsushi Ochiai, T Sugimura, Michiie Sakamoto, Kenta Yoshiura, Masatoshi Takeichi, Kenichi Takayasu and Tatsuhiro Shibata. Their work appears in journals such as Japanese Journal of Clinical Oncology, British Journal of Cancer, Biochemical and Biophysical Research Communications, Radiology and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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