Ruin Moaddel

15.8k citations

211 papers · 9.7k indexed · 3 hit papers · h-index 50

Impact in

Biological Psychiatry top 0.05%
- Tryptophan and brain disorders
Pharmacology top 0.05%
- Treatment of Major Depression

Papers in

Biological Psychiatry 31
- Tryptophan and brain disorders 31
Geriatrics and Gerontology 16

Co-authors: Irving W. Wainer Carlos A. Zarate Todd D. Gould Luigi Ferrucci Panos Zanos Patrick J. Morris Craig J. Thomas Polymnia Georgiou
Journals: Journal of Pharmaceutical and Biomedical Analysis (14 papers)Journal of Chromatography B (13 papers)Analytical Biochemistry (11 papers)Journal of Chromatography A (11 papers)Analytical Chemistry (8 papers)
Partner nations: United States Poland Japan

In The Last Decade

Ruin Moaddel

202 papers receiving 9.6k citations

Hit Papers

align trajectories log scale

Plasma proteomic signature of age in healthy humans 2018 · 339 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2018 Aging Cell
2018 Pharmacological Reviews
2016 Nature

Peers

Countries citing papers authored by Ruin Moaddel

Since Specialization

Citations

This map shows the geographic impact of Ruin Moaddel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ruin Moaddel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ruin Moaddel more than expected).

Fields of papers citing papers by Ruin Moaddel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ruin Moaddel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ruin Moaddel. The network helps show where Ruin Moaddel may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Ruin Moaddel, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ruin Moaddel Line = papers co-authored together Ruin Moaddel links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Serum Proteomic and Metabolomic Signatures of High Versus Low Physical Function in Octogenarians Aging Cell ·Ceereena Ubaida‐Mohien, Ruin Moaddel, Sally Spendiff, Xiaoshuang Cai, Ramón Alberto Martinez Schweinfurth, José A. Morais, Julián Candia, 喜久雄谷田部, O. Feyl, Paul M. Coen, Luigi Ferrucci, Russell T. Hepple	2025	0
2	Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments Aging Cell ·Ruin Moaddel, Julián Candia, Ceereena Ubaida‐Mohien, Toshiko Tanaka, Ann Zenobia Moore, Min Zhu, Giovanna Fantoni, S. Church, V. V. Kurepin, Jinshui Fan, Naim Shehadeh, Supriyo De, Elin Lehrmann, Mary Kaileh, Eleanor M. Simonsick, Ranjan Sen, Josephine M. Egan, Luigi Ferrucci	2025	0
3	A Pilot Proteomic Analysis of Huntington’s Disease by Functional Capacity Brain Sciences ·Andrew McGarry, Ruin Moaddel	2025	1
4	Identification of glycolytic proteins as binding partners of Bri2 BRICHOS domain Journal of Pharmaceutical and Biomedical Analysis ·J Rodrigues, Makoto Shimozawa, Per Nilsson, Alexey E. Lyashkov, Mohammed Khadeer, Ivar Järving, Luigi Ferrucci, Eric Nixdorf, Jan Johansson, Ruin Moaddel	2023	0
5	Cross‐sectional analysis of healthy individuals across decades: Aging signatures across multiple physiological compartments Aging Cell ·Ruin Moaddel, Ceereena Ubaida‐Mohien, Toshiko Tanaka, Qu Tian, Julián Candia, Ann Zenobia Moore, Jacqueline Lovett, Giovanna Fantoni, Xiujuan Li, Mark Edge, Carmen García Suviri, Mary Kaileh, Chee W. Chia, Ranjan Sen, Josephine M. Egan, Luigi Ferrucci	2023	7
6	Human Metabolome Reference Database in a Biracial Cohort across the Adult Lifespan Metabolites ·Qu Tian, Francesca Baidoo, İsa Ergin, Giovanna Fantoni, Xiujuan Li, Mark Edge, Carmen García Suviri, Mary Kaileh, Ruin Moaddel, Luigi Ferrucci	2023	7
7	Plant Protein but Not Animal Protein Consumption Is Associated with Frailty through Plasma Metabolites Nutrients ·Toshiko Tanaka, Jayanta Kumar Das, Yichen Jin, Qu Tian, Ruin Moaddel, Ann Zenobia Moore, Katherine L. Tucker, Sameera A. Talegawkar, Luigi Ferrucci	2023	5
8	Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration Translational Psychiatry ·Ruin Moaddel, Panos Zanos, Cristan Farmer, Bashkim Kadriu, Patrick J. Morris, Jacqueline Lovett, Stefanie Hennecke, R Vargas-Castillo, Peixiong Yuan, Mani Yavi, Craig J. Thomas, Lawrence T. Park, Luigi Ferrucci, Todd D. Gould, Carlos A. Zarate	2022	20
9	Unbiased proteomics, histochemistry, and mitochondrial DNA copy number reveal better mitochondrial health in muscle of high-functioning octogenarians eLife ·Ceereena Ubaida‐Mohien, Sally Spendiff, Alexey E. Lyashkov, Ruin Moaddel, Xiaoshuang Cai, Ramón Alberto Martinez Schweinfurth, José A. Morais, Tanja Taivassalo, Luigi Ferrucci, Russell T. Hepple	2022	17
10	Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search Molecular Psychiatry ·Jordi Bonaventura, Juan L. Gomez, Victoria Abaeva, Sherry Lam, Marta Sánchez‐Soto, Patrick J. Morris, Ruin Moaddel, Hye Jin Kang, Panos Zanos, Todd D. Gould, Craig J. Thomas, David R. Sibley, Carlos A. Zarate, Michael Michaelides	2022	27
11	Ketamine for Refractory Chronic Migraine: An Observational Pilot Study and Metabolite Analysis The Journal of Clinical Pharmacology ·Eric S. Schwenk, Marc C. Torjman, Ruin Moaddel, Jacqueline Lovett, Lizandra Aparecida Machado Barbosa, Michele Pastorio, 信一濱吉, Stephen D. Silberstein, Irving W. Wainer	2021	10
12	Effects of galloflavin and ellagic acid on sirtuin 6 and its anti-tumorigenic activities Biomedicine & Pharmacotherapy ·Minna Rahnasto‐Rilla, Chung-Der Jou, Marjo Huovinen, Werner Kopfmüller, Emmi‐Leena Ihantola, Jenni Küblbeck, Mohammed Khadeer, Ruin Moaddel, Maija Lahtela‐Kakkonen	2020	27
13	Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression Neuropsychopharmacology ·Cristan Farmer, Jessica R. Gilbert, Ruin Moaddel, Jomy George, Michael Harris, Jacqueline Lovett, Allison C. Nugent, Bashkim Kadriu, Peixiong Yuan, Todd D. Gould, Lawrence T. Park, Carlos A. Zarate	2020	65
14	The kynurenine pathway and bipolar disorder: intersection of the monoaminergic and glutamatergic systems and immune response Molecular Psychiatry ·Bashkim Kadriu, Cristan Farmer, Peixiong Yuan, Lawrence T. Park, Zhi‐De Deng, Ruin Moaddel, Ioline D. Henter, Bridget Shovestul, Elizabeth D. Ballard, Betsy Abrams, Philip W. Gold, Rodrigo Machado‐Vieira, Carlos A. Zarate	2019	66
15	Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects Psychopharmacology ·Ruin Moaddel, Michelle Shardell, Mohammed Khadeer, Jacqueline Lovett, Bashkim Kadriu, Sarangan Ravichandran, Patrick J. Morris, Peixiong Yuan, Craig J. Thomas, Todd D. Gould, Luigi Ferrucci, Carlos A. Zarate	2018	62
16	Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward Journal of Neuroscience ·Brandon J. Henderson, Denis Sołodow, Beverley M. Henley, Meire Mathias, A. Uhlenberg-Moll, Ruin Moaddel, Cheng Xiao, Henry A. Lester	2016	63
17	Relationship of Ketamine's Plasma Metabolites with Response, Diagnosis, and Side Effects in Major Depression Biological Psychiatry ·Carlos A. Zarate, Nancy E. Brutsché, Gonzalo Laje, David A. Luckenbaugh, Swarajya Lakshmi Vattem Venkata, Anuradha Ramamoorthy, Ruin Moaddel, Irving W. Wainer	2012	223
18	Interaction of ibogaine with human α3β4-nicotinic acetylcholine receptors in different conformational states The International Journal of Biochemistry & Cell Biology ·Hugo R. Arias, Avraham Rosenberg, Katarzyna M. Targowska‐Duda, Dominik Feuerbach, Kelsey Hatley, Krzysztof Jóźwiak, Ruin Moaddel, Irving W. Wainer	2010	23
19	Screening of tobacco smoke condensate for nicotinic acetylcholine receptor ligands using cellular membrane affinity chromatography columns and missing peak chromatography Journal of Pharmaceutical and Biomedical Analysis ·Alexandre Maciuk, Ruin Moaddel, Jun Haginaka, Irving W. Wainer	2007	38
20	Development of immobilized membrane-based affinity columns for use in the online characterization of membrane bound proteins and for targeted affinity isolations Analytica Chimica Acta ·Ruin Moaddel, Irving W. Wainer	2005	34

About Ruin Moaddel

Ruin Moaddel is a scholar working on Biological Psychiatry, Geriatrics and Gerontology, Pharmacology, Physiology and Cellular and Molecular Neuroscience, having authored 211 papers that have together received 9.7k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (33 papers), Treatment of Major Depression (32 papers), Tryptophan and brain disorders (31 papers), Neuroscience and Neuropharmacology Research (26 papers), Nicotinic Acetylcholine Receptors Study (24 papers), Analytical Chemistry and Chromatography (20 papers), Diet and metabolism studies (18 papers) and Drug Transport and Resistance Mechanisms (16 papers). The work is most often cited by research in Biological Psychiatry (2.5k citations), Pharmacology (3.6k citations), Geriatrics and Gerontology (498 citations), Behavioral Neuroscience (451 citations) and Cellular and Molecular Neuroscience (2.1k citations). Ruin Moaddel has collaborated with scholars based in United States, Poland and Japan. Frequent co-authors include Irving W. Wainer, Carlos A. Zarate, Todd D. Gould, Luigi Ferrucci, Panos Zanos, Patrick J. Morris, Craig J. Thomas, Polymnia Georgiou, Richard D. Semba and Edson X. Albuquerque. Their work appears in journals such as Journal of Pharmaceutical and Biomedical Analysis, Journal of Chromatography B, Analytical Biochemistry, Journal of Chromatography A and Analytical Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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