Rui Zhou

4.5k total citations · 1 hit paper
80 papers, 3.1k citations indexed

About

Rui Zhou is a scholar working on Molecular Biology, Physiology and Computational Theory and Mathematics. According to data from OpenAlex, Rui Zhou has authored 80 papers receiving a total of 3.1k indexed citations (citations by other indexed papers that have themselves been cited), including 43 papers in Molecular Biology, 24 papers in Physiology and 8 papers in Computational Theory and Mathematics. Recurrent topics in Rui Zhou's work include Alzheimer's disease research and treatments (18 papers), Protein Structure and Dynamics (8 papers) and Computational Drug Discovery Methods (8 papers). Rui Zhou is often cited by papers focused on Alzheimer's disease research and treatments (18 papers), Protein Structure and Dynamics (8 papers) and Computational Drug Discovery Methods (8 papers). Rui Zhou collaborates with scholars based in China, United States and United Kingdom. Rui Zhou's co-authors include Yigong Shi, Guanghui Yang, Linfeng Sun, Chuangye Yan, Xuefei Guo, Jianlin Lei, Peilong Lu, Dan Ma, Xiao‐chen Bai and Sjors H. W. Scheres and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Rui Zhou

73 papers receiving 3.1k citations

Hit Papers

An atomic structure of human γ-secretase 2015 2026 2018 2022 2015 100 200 300 400
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. An atomic structure of human γ-secretase
    2015 406 citations Chuangye Yan, Guanghui Yang et al. profile →

Peers

Rui Zhou
Linfeng Sun China
Johnny Habchi United Kingdom
Guanghui Yang China
Anthony W. P. Fitzpatrick United States
Jörg Labahn Germany
Catherine C. L. Wong United States
Erhu Cao United States
Gian Gaetano Tartaglia Italy
Sarah Meehan United Kingdom
X. Edward Zhou China
Linfeng Sun China
Rui Zhou
Citations per year, relative to Rui Zhou Rui Zhou (= 1×) peers Linfeng Sun

Countries citing papers authored by Rui Zhou

Since Specialization
Citations

This map shows the geographic impact of Rui Zhou's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rui Zhou with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rui Zhou more than expected).

Fields of papers citing papers by Rui Zhou

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rui Zhou. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rui Zhou. The network helps show where Rui Zhou may publish in the future.

Co-authorship network of co-authors of Rui Zhou

This figure shows the co-authorship network connecting the top 25 collaborators of Rui Zhou. A scholar is included among the top collaborators of Rui Zhou based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Rui Zhou. Rui Zhou is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Gao, Shipeng, Junyong Zhu, Yang Zhang, et al.. (2025). Magnetic nanoprobe-enabled lateral flow assays in the applications of food safety and in vitro diagnostic. Coordination Chemistry Reviews. 534. 216588–216588. 14 indexed citations
2.
Zhang, Weixiao, Bingxin Liu, Sai Wang, et al.. (2025). Echinococcus granulosus antigen B ameliorates myocardial infarction through promoting M2 macrophage polarization. Frontiers in Cellular and Infection Microbiology. 15. 1662758–1662758.
3.
Saeed, Anum, Jubao Duan, Rui Zhou, et al.. (2024). Oral Disease and Atherosclerosis May Be Associated with Overlapping Metabolic Pathways. JDR Clinical & Translational Research. 10(3). 315–323. 1 indexed citations
4.
Guo, Xuefei, Hao Liu, Chuangye Yan, et al.. (2024). Structural basis of human γ-secretase inhibition by anticancer clinical compounds. Nature Structural & Molecular Biology. 32(4). 719–728. 4 indexed citations
5.
Guo, Xuefei, et al.. (2024). Molecular mechanism of substrate recognition and cleavage by human γ-secretase. Science. 384(6700). 1091–1095. 16 indexed citations
6.
Zhou, Rui, Masato Maesako, N. Hung, et al.. (2024). Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes. Cell Reports. 43(2). 113761–113761. 15 indexed citations
7.
Jiang, Tao, et al.. (2023). Molecular Insights on the Conformational Transitions and Activity Regulation of the c-Met Kinase Induced by Ligand Binding. Journal of Chemical Information and Modeling. 63(13). 4147–4157. 3 indexed citations
8.
Zhou, Rui, et al.. (2023). The Conformational Transitions and Dynamics of Burkholderia cepacia Lipase Regulated by Water–Oil Interfaces. Journal of Chemical Information and Modeling. 63(12). 3854–3864. 8 indexed citations
9.
Guo, Yue, Shengqing Ye, Jintu Zhang, et al.. (2023). On the Dynamic Mechanism of Long-Flexible Fatty Acid Binding to Fatty Acid Binding Protein: Resolving the Long-Standing Debate. Journal of Chemical Information and Modeling. 63(16). 5232–5243. 1 indexed citations
10.
Zhou, Rui, Xiaqin Sun, Jinxin Wang, et al.. (2023). Preferential Regulation of Γ‐Secretase‐Mediated Cleavage of APP by Ganglioside GM1 Reveals a Potential Therapeutic Target for Alzheimer's Disease. Advanced Science. 10(32). e2303411–e2303411. 9 indexed citations
11.
Wang, Shuying, F. Huang, Yayun Qian, et al.. (2023). Therapeutic effect of Echinococcus granulosus cyst fluid on bacterial sepsis in mice. Parasites & Vectors. 16(1). 450–450. 8 indexed citations
12.
Wang, Shuying, Huihui Li, Xiaoli Wang, et al.. (2023). Excretory/secretory products from Trichinella spiralis adult worms ameliorate myocardial infarction by inducing M2 macrophage polarization in a mouse model. Parasites & Vectors. 16(1). 362–362. 3 indexed citations
13.
Zhou, Rui, et al.. (2022). Phosphorylation Regulation on the Homo-Dimeric Binding of Transactive Response DNA-Binding Protein. Journal of Chemical Information and Modeling. 62(21). 5267–5275. 1 indexed citations
14.
Zhou, Rui, Jinping Pang, Yue Guo, et al.. (2021). Molecular View on the Dissociation Pathways and Transactivation Regulation Mechanism of Nonsteroidal GR Ligands. Journal of Chemical Information and Modeling. 62(21). 5233–5245. 7 indexed citations
15.
Zhou, Rui, Guanghui Yang, Xuefei Guo, et al.. (2019). Recognition of the amyloid precursor protein by human γ-secretase. Science. 363(6428). 237 indexed citations
16.
Zhou, Rui, Juan Niu, Tao Xu, et al.. (2017). P2Y<sub>12 </sub>and P2Y<sub>13</sub> receptors involved in ADP&beta;s induced the release of IL-1&beta;, IL-6 and TNF-&alpha; from cultured dorsal horn microglia. Journal of Pain Research. Volume 10. 1755–1767. 38 indexed citations
17.
Sun, Linfeng, Lingyun Zhao, Guanghui Yang, et al.. (2015). Structural basis of human γ-secretase assembly. Proceedings of the National Academy of Sciences. 112(19). 6003–6008. 84 indexed citations
18.
Zhou, Rui, et al.. (2015). Clinical study on HAT and SEDAN score scales and related risk factors for predicting hemorrhagic transformation following thrombolysis in acute ischemic stroke. SHILAP Revista de lepidopterología. 2 indexed citations
19.
Li, Bo, Rui Zhou, Gu He, Li Guo, & Wei Huang. (2013). Molecular Docking, QSAR and Molecular Dynamics Simulation on Spiro-oxindoles as MDM2 Inhibitors. Acta Chimica Sinica. 71(10). 1396–1396. 6 indexed citations
20.
Zhou, Rui, et al.. (2008). Electroporation-Mediated Gene Delivery to the Lungs. Methods in molecular biology. 1121. 233–247. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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2026