Robert W. Wiethe

1.3k total citations · 1 hit paper
20 papers, 1.0k citations indexed

About

Robert W. Wiethe is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Pharmacology. According to data from OpenAlex, Robert W. Wiethe has authored 20 papers receiving a total of 1.0k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 10 papers in Cellular and Molecular Neuroscience and 5 papers in Pharmacology. Recurrent topics in Robert W. Wiethe's work include Cannabis and Cannabinoid Research (5 papers), Receptor Mechanisms and Signaling (5 papers) and Neuropeptides and Animal Physiology (5 papers). Robert W. Wiethe is often cited by papers focused on Cannabis and Cannabinoid Research (5 papers), Receptor Mechanisms and Signaling (5 papers) and Neuropeptides and Animal Physiology (5 papers). Robert W. Wiethe collaborates with scholars based in United States, Canada and Netherlands. Robert W. Wiethe's co-authors include Timothy M. Willson, David J. Cowan, Steven A. Kliewer, Linda B. Moore, Jürgen M. Lehmann, Shimoga R. Prakash, Jeffery E. Cobb, Micheal D. Gaul, C. Fred Hassman and Rodolfo Cadilla and has published in prestigious journals such as Journal of Medicinal Chemistry, Tetrahedron and Bioorganic & Medicinal Chemistry.

In The Last Decade

Robert W. Wiethe

20 papers receiving 998 citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Structure−Activity Relationship between Peroxisome Proliferator-Activated Receptor γ Agonism and the Antihyperglycemic Activity of Thiazolidinediones

1996 569 citations Timothy M. Willson, Jeffery E. Cobb et al. Journal of Medicinal Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Robert W. Wiethe United States	11	846	196	155	146	89	20	1.0k
Melvin Reichman United States	16	350 0.4×	72 0.4×	108 0.7×	112 0.8×	50 0.6×	28	852
Salida Mirzoeva United States	18	528 0.6×	89 0.5×	134 0.9×	45 0.3×	60 0.7×	24	977
Melinda M. Mulvihill United States	15	603 0.7×	62 0.3×	204 1.3×	48 0.3×	80 0.9×	24	1.0k
Hélène Perrier Canada	13	531 0.6×	185 0.9×	199 1.3×	217 1.5×	21 0.2×	19	944
JOHN H. MUSSER United States	17	446 0.5×	170 0.9×	178 1.1×	448 3.1×	28 0.3×	55	1.1k
Seung Hun Jeong South Korea	17	546 0.6×	95 0.5×	73 0.5×	75 0.5×	35 0.4×	33	854
Lidia Ciccone Italy	18	484 0.6×	178 0.9×	103 0.7×	117 0.8×	28 0.3×	56	808
A.V. Wallace United Kingdom	15	326 0.4×	198 1.0×	52 0.3×	165 1.1×	67 0.8×	20	706
Lawrence M. Szewczuk United States	15	860 1.0×	79 0.4×	65 0.4×	152 1.0×	44 0.5×	20	1.2k
Ja Young Koo South Korea	13	395 0.5×	77 0.4×	64 0.4×	152 1.0×	29 0.3×	25	684

Countries citing papers authored by Robert W. Wiethe

Since Specialization

Citations

This map shows the geographic impact of Robert W. Wiethe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert W. Wiethe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert W. Wiethe more than expected).

Fields of papers citing papers by Robert W. Wiethe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert W. Wiethe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert W. Wiethe. The network helps show where Robert W. Wiethe may publish in the future.

Co-authorship network of co-authors of Robert W. Wiethe

This figure shows the co-authorship network connecting the top 25 collaborators of Robert W. Wiethe. A scholar is included among the top collaborators of Robert W. Wiethe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert W. Wiethe. Robert W. Wiethe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Thornburg, Jonathan, et al.. (2021). Thermal Degradants Identified from the Vaping of Vitamin E Acetate. Journal of Analytical Toxicology. 46(7). 750–756. 6 indexed citations

Amato, George, Robert W. Wiethe, Amruta Manke, et al.. (2019). Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor – SAR efforts towards selectivity and peripheralization. Bioorganic & Medicinal Chemistry. 27(16). 3632–3649. 2 indexed citations

Amato, George, Amruta Manke, Robert W. Wiethe, et al.. (2019). Functionalized 6-(Piperidin-1-yl)-8,9-Diphenyl Purines as Peripherally Restricted Inverse Agonists of the CB1 Receptor. Journal of Medicinal Chemistry. 62(13). 6330–6345. 9 indexed citations

Amato, George, Amruta Manke, Robert W. Wiethe, et al.. (2018). Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists. Bioorganic & Medicinal Chemistry. 26(15). 4518–4531. 4 indexed citations

Amato, George, Amruta Manke, Danni L. Harris, et al.. (2018). Blocking Alcoholic Steatosis in Mice with a Peripherally Restricted Purine Antagonist of the Type 1 Cannabinoid Receptor. Journal of Medicinal Chemistry. 61(10). 4370–4385. 24 indexed citations

Zhang, Yanan, Herbert H. Seltzman, Rodney W. Snyder, et al.. (2016). Pyrazole antagonists of the CB1 receptor with reduced brain penetration. Bioorganic & Medicinal Chemistry. 24(5). 1063–1070. 17 indexed citations

Thomas, James B., Robert W. Wiethe, Alexandre Murza, et al.. (2016). Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a Selective Antagonist for the Rat Neurotensin Receptor Type 2. ACS Chemical Neuroscience. 7(9). 1225–1231. 8 indexed citations

Thomas, James B., O. Srinivas, Robert W. Wiethe, et al.. (2015). The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2. Bioorganic & Medicinal Chemistry Letters. 25(10). 2060–2064. 2 indexed citations

Thomas, James B., Robert W. Wiethe, O. Srinivas, et al.. (2014). Identification of 1-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1 H -pyrazol-3-yl]carbonyl}amino)cyclohexane Carboxylic Acid as a Selective Nonpeptide Neurotensin Receptor Type 2 Compound. Journal of Medicinal Chemistry. 57(12). 5318–5332. 20 indexed citations

10.

Thomas, James B., Robert W. Wiethe, O. Srinivas, et al.. (2014). Identification ofN-[(5-{[(4-Methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-l-leucine (NTRC-824), a Neurotensin-like Nonpeptide Compound Selective for the Neurotensin Receptor Type 2. Journal of Medicinal Chemistry. 57(17). 7472–7477. 17 indexed citations

11.

Thomas, James B., O. Srinivas, Robert W. Wiethe, et al.. (2014). Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2. Bioorganic & Medicinal Chemistry Letters. 25(2). 292–296. 5 indexed citations

12.

Shearer, Barry G., Robert W. Wiethe, Andrew N. Billin, et al.. (2010). Identification and Characterization of 4-Chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a Selective and Irreversible Peroxisome Proliferator-Activated Receptor δ (PPARδ) Antagonist. Journal of Medicinal Chemistry. 53(4). 1857–1861. 61 indexed citations

13.

Wiethe, Robert W., et al.. (2006). Array synthesis of progesterone receptor antagonists: 3-Aryl-1,2-diazepines. Bioorganic & Medicinal Chemistry Letters. 16(14). 3777–3779. 14 indexed citations

14.

Wiethe, Robert W., et al.. (2006). Array Synthesis of Progesterone Receptor Antagonists: 3‐Aryl‐1,2‐diazepines.. ChemInform. 37(41). 1 indexed citations

15.

Lambert, Millard H., Theresa Seaton, Daniel B. Kassel, et al.. (2005). Substrate Specificity and Novel Selective Inhibitors of TNF-α Converting Enzyme (TACE) from Two-Dimensional Substrate Mapping. Combinatorial Chemistry & High Throughput Screening. 8(4). 327–339. 21 indexed citations

16.

Henke, Brad R., et al.. (2001). 2-Amino-4,6-diarylpyridines as novel ligands for the estrogen receptor. Bioorganic & Medicinal Chemistry Letters. 11(14). 1939–1942. 25 indexed citations

17.

Willson, Timothy M., Jeffery E. Cobb, David J. Cowan, et al.. (1996). The Structure−Activity Relationship between Peroxisome Proliferator-Activated Receptor γ Agonism and the Antihyperglycemic Activity of Thiazolidinediones. Journal of Medicinal Chemistry. 39(3). 665–668. 569 indexed citations breakdown →

18.

Thomson, Stephen A., John A. Josey, Rodolfo Cadilla, et al.. (1995). ChemInform Abstract: Fmoc‐Mediated Synthesis of Peptide Nucleic Acids.. ChemInform. 26(38). 3 indexed citations

19.

Noble, Stewart A., Michele A. Bonham, John Bisi, et al.. (1995). Impact of biophysical parameters on the biological assessment of peptide nucleic acids, antisense inhibitors of gene expression. Drug Development Research. 34(2). 184–195. 22 indexed citations

20.

Thomson, Stephen A., John A. Josey, Rodolfo Cadilla, et al.. (1995). Fmoc mediated synthesis of Peptide Nucleic Acids. Tetrahedron. 51(22). 6179–6194. 212 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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