Robert Lai

3.6k citations

61 papers · 2.7k indexed · 1 hit paper · h-index 25

Impact in

Physiology top 1%
- Alzheimer's disease research and treatments
- Pain Mechanisms and Treatments
Biological Psychiatry top 5%

Papers in ⓘ

Physiology 33
- Alzheimer's disease research and treatments 23
Sensory Systems 5

Co-authors: Claude M. Wischik (5 shared papers)Charles R. Harrington (5 shared papers)Patricia C. Edwards (4 shared papers)Martin Roth (4 shared papers)June Kaplow (14 shared papers)Chad J. Swanson (12 shared papers)Lars Lannfelt (7 shared papers)Boris A. Chizh (3 shared papers)
Journals: Alzheimer s & Dementia (20 papers)Neurobiology of Aging (5 papers)European Journal of Pain (3 papers)Alzheimer s Research & Therapy (3 papers)Journal of Nuclear Medicine (2 papers)
Partner nations: United Kingdom United States Japan

In The Last Decade

Robert Lai

58 papers receiving 2.6k citations

Hit Papers

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A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer’s disease with lecanemab, an anti-Aβ protofibril antibody 2021 · 580 citations

Peers

Countries citing papers authored by Robert Lai

Since Specialization

Citations

This map shows the geographic impact of Robert Lai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert Lai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert Lai more than expected).

Fields of papers citing papers by Robert Lai

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert Lai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert Lai. The network helps show where Robert Lai may publish in the future.

Co-authors

The 25 scholars most cited alongside Robert Lai, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Robert Lai Line = papers co-authored together Robert Lai links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 61 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer’s disease with lecanemab, an anti-Aβ protofibril antibody Alzheimer s Research & Therapy ·Chad J. Swanson, Yong Zhang, Shobha Dhadda, Jinping Wang, June Kaplow, Robert Lai, Lars Lannfelt, Heather Bradley, Martin Rabe, Akihiko Koyama, Larisa Reyderman, Donald A. Berry, Scott Berry, Robert J. Gordon, Lynn D. Kramer, Jeffrey L. Cummings Hit paper breakdown →	2021	580
2	Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines. Proceedings of the National Academy of Sciences ·Claude M. Wischik, Patricia C. Edwards, Robert Lai, Martin Roth, Charles R. Harrington	1996	438
3	Safety and tolerability of BAN2401 - a clinical study in Alzheimer’s disease with a protofibril selective Aβ antibody Alzheimer s Research & Therapy ·Veronika Logovinsky, Andrew Satlin, Robert Lai, Chad J. Swanson, June Kaplow, Gunilla Osswald, Hans Basun, Lars Lannfelt	2016	212
4	The effects of the TRPV1 antagonist SB-705498 on TRPV1 receptor-mediated activity and inflammatory hyperalgesia in humans Pain ·Boris A. Chizh, M. O'Donnell, Antonella Napolitano, Jie Wang, Allison C. Brooke, Mike Aylott, Jonathan Bullman, Emily J. Gray, Robert Lai, Pauline Williams, Jonathan Appleby	2007	199
5	Clinical trial of the p38 MAP kinase inhibitor dilmapimod in neuropathic pain following nerve injury European Journal of Pain ·Praveen Anand, Ravikiran Shenoy, Joanne Palmer, Amanda Baines, Robert Lai, Jonathan Robertson, Nick Bird, Thor Ostenfeld, Boris A. Chizh	2011	133
6	Chronic Oral Gabapentin Reduces Elements of Central Sensitization in Human Experimental Hyperalgesia Anesthesiology ·Hanne Gottrup, Gitte Irene Juhl, Anders D. Kristensen, Robert Lai, Boris A. Chizh, John H. Brown, Flemming W. Bach, Troels S. Jensen	2004	103
7	A simultaneous ERP/fMRI investigation of the P300 aging effect Neurobiology of Aging ·Redmond G O’Connell, Joshua H. Balsters, Sophia M. Kilcullen, W. Keith Campbell, Arun L.W. Bokde, Robert Lai, Neil Upton, Ian H. Robertson	2012	98
8	Pittsburgh Compound B (11C-PIB) and Fluorodeoxyglucose (18 F-FDG) PET in Patients With Alzheimer Disease, Mild Cognitive Impairment, and Healthy Controls Journal of Geriatric Psychiatry and Neurology ·Davangere P. Devanand, Arthur Mikhno, Gregory H. Pelton, Katrina Cuasay, Gnanavalli Pradhaban, J.S. Dileep Kumar, Neil Upton, Robert Lai, Roger N. Gunn, Vincenzo Libri, Xinhua Liu, Ronald Van Heertum, J. John Mann, Ramin V. Parsey	2010	88
9	Enhanced Sensitivity of Insulin-resistant Adipocytes to Vanadate Is Associated with Oxidative Stress and Decreased Reduction of Vanadate (+5) to Vanadyl (+4) Journal of Biological Chemistry ·Bing Lu, David Ennis, Robert Lai, Elena Bogdanovic, Rinna Nikolov, Lisa Salamon, Claire Fantus, Hoang Le‐Tien, I. George Fantus	2001	83
10	Evaluation of¹¹C-GSK189254 as a Novel Radioligand for the H₃Receptor in Humans Using PET Journal of Nuclear Medicine ·Sharon Ashworth, Eugenii A. Rabiner, Roger N. Gunn, Christophe Plisson, Alan A. Wilson, Robert A. Comley, Robert Lai, Antony D. Gee, Marc Laruelle, Vincent J. Cunningham	2010	55
11	The Safety, Tolerability, Pharmacokinetics and Cognitive Effects of GSK239512, a Selective Histamine H<sub>3</sub> Receptor Antagonist in Patients with Mild to Moderate Alzheimer’s Disease: A Preliminary Investigation Current Alzheimer Research ·Pradeep J. Nathan, Rebecca Boardley, Nicola Scott, Aliénor Berges, Paul Maruff, Tharani Sivananthan, Neil Upton, Martin T. Lowy, Peter J. Nestor, Robert Lai	2013	54
12	Quantitative analysis of tau protein in paired helical filament preparations: Implications for the role of tau protein phosphorylation in PHF assembly in Alzheimer's disease Neurobiology of Aging ·Claude M. Wischik, Patricia C. Edwards, Robert Lai, Herman N.-J. Gertz, John H. Xuereb, Eugene S. Paykel, Carol Brayne, Felicia A. Huppert, Elizabeta B. Mukaetova‐Ladinska, Raúl Mena, Martin Roth, Charles R. Harrington	1995	51
13	Modulation of insulin action by vanadate: evidence of a role for phosphotyrosine phosphatase activity to alter cellular signaling Molecular and Cellular Biochemistry ·I. George Fantus, G. Deragon, Robert Lai, Shangguo Tang	1995	50
14	O1‐06‐05: First‐in‐human study of E2609, a novel BACE1 inhibitor, demonstrates prolonged reductions in plasma beta‐amyloid levels after single dosing Alzheimer s & Dementia ·Robert Lai, Bruce Albala, June Kaplow, Jagadeesh Aluri, Mark Yen, Andrew Satlin	2012	46
15	Changes in resting connectivity with age: a simultaneous electroencephalogram and functional magnetic resonance imaging investigation Neurobiology of Aging ·Joshua H. Balsters, Redmond G O’Connell, Alessandra Galli, Hugh Nolan, Eleanora Greco, Sophia M. Kilcullen, Arun L.W. Bokde, Robert Lai, Neil Upton, Ian H. Robertson	2013	41
16	Donepezil Impairs Memory in Healthy Older Subjects: Behavioural, EEG and Simultaneous EEG/fMRI Biomarkers PLoS ONE ·Joshua H. Balsters, Redmond G O’Connell, Mary P. Martin, Alessandra Galli, Sarah M. Cassidy, Sophia M. Kilcullen, Sonja Delmonte, Sabina Brennan, James F. Meaney, Andrew Fagan, Arun L.W. Bokde, Neil Upton, Robert Lai, Marc Laruelle, Brian Lawlor, Ian H. Robertson	2011	40
17	Voxel-Based Analysis of ¹¹C-PIB Scans for Diagnosing Alzheimer's Disease Journal of Nuclear Medicine ·Arthur Mikhno, Davangere P. Devanand, Gregory H. Pelton, Katrina Cuasay, Roger N. Gunn, Neil Upton, Robert Lai, Vincenzo Libri, J. John Mann, Ramin V. Parsey	2008	36
18	A Randomized, Placebo-controlled Trial of the Analgesic Efficacy and Safety of the p38 MAP Kinase Inhibitor, Losmapimod, in Patients With Neuropathic Pain From Lumbosacral Radiculopathy Clinical Journal of Pain ·Thor Ostenfeld, Alok Krishen, Robert Lai, Jonathan Bullman, Jonathan Green, Praveen Anand, Joachim Scholz, M. Kelly	2014	34
19	A Comparison of Gray Matter Density in Restless Legs Syndrome Patients and Matched Controls Using Voxel‐Based Morphometry Journal of Neuroimaging ·Robert A. Comley, Simon Červenka, Sven Pålhagen, Georgios Panagiotidis, Julian C. Matthews, Robert Lai, Christer Halldin, Lars Farde, Thomas E. Nichols, Brandon Whitcher	2010	33
20	Electrophysiological entropy in younger adults, older controls and older cognitively declined adults Brain Research ·Michael Hogan, Liam Kilmartin, Michael Keane, Peter Collins, Roger T. Staff, Jochen Kaiser, Robert Lai, Neil Upton	2012	29

About Robert Lai

Robert Lai is a scholar working on Physiology, Sensory Systems, Psychiatry and Mental health, Pharmacology and Cognitive Neuroscience, having authored 61 papers that have together received 2.7k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (23 papers), Cholinesterase and Neurodegenerative Diseases (11 papers), Computational Drug Discovery Methods (8 papers), Dementia and Cognitive Impairment Research (7 papers), Neural and Behavioral Psychology Studies (6 papers), Phosphodiesterase function and regulation (5 papers), 14-3-3 protein interactions (5 papers) and Neural dynamics and brain function (5 papers). The work is most often cited by research in Physiology (1.6k citations), Biological Psychiatry (111 citations), Sensory Systems (200 citations), Neurology (308 citations) and Pharmacology (614 citations). Robert Lai has collaborated with scholars based in United Kingdom, United States and Japan. Frequent co-authors include Claude M. Wischik, Charles R. Harrington, Patricia C. Edwards, Martin Roth, June Kaplow, Chad J. Swanson, Lars Lannfelt, Boris A. Chizh, Neil Upton and Jinping Wang. Their work appears in journals such as Alzheimer s & Dementia, Neurobiology of Aging, European Journal of Pain, Alzheimer s Research & Therapy and Journal of Nuclear Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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