Raffaella Melfi

2.6k total citations · 1 hit paper
43 papers, 2.1k citations indexed

About

Raffaella Melfi is a scholar working on Molecular Biology, Genetics and Pulmonary and Respiratory Medicine. According to data from OpenAlex, Raffaella Melfi has authored 43 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 32 papers in Molecular Biology, 12 papers in Genetics and 6 papers in Pulmonary and Respiratory Medicine. Recurrent topics in Raffaella Melfi's work include RNA and protein synthesis mechanisms (12 papers), Genomics and Chromatin Dynamics (10 papers) and Epigenetics and DNA Methylation (8 papers). Raffaella Melfi is often cited by papers focused on RNA and protein synthesis mechanisms (12 papers), Genomics and Chromatin Dynamics (10 papers) and Epigenetics and DNA Methylation (8 papers). Raffaella Melfi collaborates with scholars based in Italy, Spain and Switzerland. Raffaella Melfi's co-authors include Vincenzo Pirrotta, Birgit Czermin, Donna McCabe, Axel Imhof, Sylvain Poux, Giovanni Spinelli, Andrea Pace, Aldo Di Leonardo, Laura Lentini and Ivana Pibiri and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Raffaella Melfi

41 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Drosophila Enhancer of Zeste/ESC Complexes Have a Histone H3 Methyltransferase Activity that Marks Chromosomal Polycomb Sites

2002 1.2k citations Birgit Czermin, Raffaella Melfi et al. Cell profile →

Peers

Raffaella Melfi

GENET

PRM

Andrew D. Johnson United Kingdom

Michihiko Ito Japan

Leonie M. Kamminga Netherlands

Shengli Cai China

Montserrat Corominas Spain

Liezhen Fu United States

Patrick Cormier France

Giovanna Benvenuto Italy

Hongxiang Zhang China

Syuiti Abe Japan

Andrew D. Johnson United Kingdom

Raffaella Melfi

1.0k ×0.6

523 ×1.7

GENET

102 ×0.4

59 ×0.6

70 ×0.8

PRM

Citations per year, relative to Raffaella Melfi Raffaella Melfi (= 1×) peers Andrew D. Johnson

Countries citing papers authored by Raffaella Melfi

Since Specialization

Citations

This map shows the geographic impact of Raffaella Melfi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Raffaella Melfi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Raffaella Melfi more than expected).

Fields of papers citing papers by Raffaella Melfi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Raffaella Melfi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Raffaella Melfi. The network helps show where Raffaella Melfi may publish in the future.

Co-authorship network of co-authors of Raffaella Melfi

This figure shows the co-authorship network connecting the top 25 collaborators of Raffaella Melfi. A scholar is included among the top collaborators of Raffaella Melfi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Raffaella Melfi. Raffaella Melfi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Lentini, Laura, Raffaella Melfi, Marco Tutone, et al.. (2025). A precision medicine approach to primary immunodeficiency disease: Ataluren strikes nonsense mutations once again. Molecular Therapy. 33(7). 3231–3241. 1 indexed citations

Pibiri, Ivana, Raffaella Melfi, Maria Grazia Zizzo, et al.. (2023). Readthrough Approach Using NV Translational Readthrough-Inducing Drugs (TRIDs): A Study of the Possible Off-Target Effects on Natural Termination Codons (NTCs) on TP53 and Housekeeping Gene Expression. International Journal of Molecular Sciences. 24(20). 15084–15084. 5 indexed citations

Tutone, Marco, Ivana Pibiri, Aldo Di Leonardo, et al.. (2023). Investigating the Inhibition of FTSJ1, a Tryptophan tRNA-Specific 2′-O-Methyltransferase by NV TRIDs, as a Mechanism of Readthrough in Nonsense Mutated CFTR. International Journal of Molecular Sciences. 24(11). 9609–9609. 9 indexed citations

Barra, Viviana, et al.. (2023). Site-Specific RNA Editing of Stop Mutations in the CFTR mRNA of Human Bronchial Cultured Cells. International Journal of Molecular Sciences. 24(13). 10940–10940. 4 indexed citations

Savoca, Dario, et al.. (2022). Uptake and photoinduced degradation of phthalic acid esters (PAEs) in Ulva lactuca highlight its potential application in environmental bioremediation. Environmental Science and Pollution Research. 29(60). 90887–90897. 13 indexed citations

Savoca, Dario, Raffaella Melfi, Antonio Palumbo Piccionello, et al.. (2021). Presence and biodistribution of perfluorooctanoic acid (PFOA) in Paracentrotus lividus highlight its potential application for environmental biomonitoring. Scientific Reports. 11(1). 18763–18763. 17 indexed citations

Pibiri, Ivana, Raffaella Melfi, Marco Tutone, et al.. (2020). Targeting Nonsense: Optimization of 1,2,4-Oxadiazole TRIDs to Rescue CFTR Expression and Functionality in Cystic Fibrosis Cell Model Systems. International Journal of Molecular Sciences. 21(17). 6420–6420. 16 indexed citations

Lentini, Laura, Aldo Di Leonardo, Raffaella Melfi, et al.. (2019). Strategies against Nonsense: Oxadiazoles as Translational Readthrough-Inducing Drugs (TRIDs). International Journal of Molecular Sciences. 20(13). 3329–3329. 36 indexed citations

Lentini, Laura, Raffaella Melfi, Aldo Di Leonardo, Ivana Pibiri, & Patrizia Cancemi. (2019). Caffeine boosts Ataluren's readthrough activity. Default journal. 5. 6 indexed citations

10.

Lentini, Laura, Raffaella Melfi, Patrizia Cancemi, Ivana Pibiri, & Aldo Di Leonardo. (2019). Caffeine boosts Ataluren's readthrough activity. Heliyon. 5(6). e01963–e01963. 18 indexed citations

11.

Pibiri, Ivana, Laura Lentini, Raffaella Melfi, et al.. (2018). Rescuing the CFTR protein function: Introducing 1,3,4-oxadiazoles as translational readthrough inducing drugs. European Journal of Medicinal Chemistry. 159. 126–142. 29 indexed citations

12.

Pibiri, Ivana, Laura Lentini, Marco Tutone, et al.. (2016). Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening. European Journal of Medicinal Chemistry. 122. 429–435. 29 indexed citations

13.

Pibiri, Ivana, Laura Lentini, Raffaella Melfi, et al.. (2015). Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives. European Journal of Medicinal Chemistry. 101. 236–244. 45 indexed citations

14.

Melfi, Raffaella, et al.. (2004). Down-regulation of Early Sea Urchin Histone H2A Gene Relies on cis Regulative Sequences Located in the 5′ and 3′ Regions and Including the Enhancer Blocker sns. Journal of Molecular Biology. 342(5). 1367–1377. 8 indexed citations

15.

Pirrotta, Vincenzo, Sylvain Poux, Raffaella Melfi, & Maxim Pilyugin. (2003). Assembly of Polycomb Complexes and Silencing Mechanisms. Genetica. 117(2-3). 191–197. 23 indexed citations

16.

Czermin, Birgit, et al.. (2002). Drosophila Enhancer of Zeste/ESC Complexes Have a Histone H3 Methyltransferase Activity that Marks Chromosomal Polycomb Sites. Cell. 111(2). 185–196. 1238 indexed citations breakdown →

17.

Leonardo, Aldo Di, et al.. (2001). The Sea Urchin sns Insulator Blocks CMV Enhancer following Integration in Human Cells. Biochemical and Biophysical Research Communications. 284(4). 987–992. 21 indexed citations

18.

Poux, Sylvain, Raffaella Melfi, & Vincenzo Pirrotta. (2001). Establishment of Polycomb silencing requires a transient interaction between PC and ESC. Genes & Development. 15(19). 2509–2514. 141 indexed citations

19.

Melfi, Raffaella, et al.. (2000). Functional Characterization of the Enhancer Blocking Element of the Sea Urchin Early Histone Gene Cluster Reveals Insulator Properties and Three Essential cis-acting Sequences. Journal of Molecular Biology. 304(5). 753–763. 23 indexed citations

20.

Russo, Roberta, et al.. (1994). Expression of homeobox-containing genes in the sea urchin (Parancentrotus lividus) embryo. Genetica. 94(2-3). 141–150. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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