Rafael M. Couñago

1.8k citations

52 papers · 1.1k indexed · h-index 20

Nutrition and Dietetics top 5%
Molecular Medicine top 10%
- Antibiotic Resistance in Bacteria 4
Molecular Biology
- Biochemical and Molecular Research 5
- Nuclear Structure and Function 4
- Protein Structure and Dynamics 3
Microbiology top 10%
Plant Science top 10%
Genetics
- Bacterial Genetics and Biotechnology 5
Oncology
- Cancer-related Molecular Pathways 4
Materials Chemistry
- Enzyme Structure and Function 4
Computational Theory and Mathematics
- Computational Drug Discovery Methods 4

Co-authors: Boštjan Kobe Yousif Shamoo Christopher A. McDevitt Alastair G. McEwan Megan L. O’Mara James C. Paton Stephen S. Chen Carlos G. Schrago
Cited by: Nutrition and Dietetics Molecular Medicine Molecular Biology
Journals: Nucleic Acids Research (1 paper)Journal of Biological Chemistry (2 papers)Nature Communications (1 paper)
Partner nations: Brazil United States Australia

In The Last Decade

Rafael M. Couñago

49 papers receiving 1.1k citations

Peers

Countries citing papers authored by Rafael M. Couñago

Since Specialization

Citations

This map shows the geographic impact of Rafael M. Couñago's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rafael M. Couñago with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rafael M. Couñago more than expected).

Fields of papers citing papers by Rafael M. Couñago

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rafael M. Couñago. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rafael M. Couñago. The network helps show where Rafael M. Couñago may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Rafael M. Couñago, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Rafael M. Couñago Line = papers co-authored together Rafael M. Couñago links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Development of a Second-Generation, In Vivo Chemical Probe for PIKfyve Journal of Medicinal Chemistry ·Sophia M. Min,Frances M. Bashore,Jeffrey L. Smith,Tammy M. Havener,Stefanie Howell,Haoxi Li,Rafael M. Couñago,Konstantin I. Popov,Alison D. Axtman	2025	1
2	N -Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad-Spectrum Antialphaviral Activity Journal of Medicinal Chemistry ·Anirban Ghoshal,John D. Sears,Mohammad Anwar Hossain,Edwin G. Tse,Stefanie Howell,Jane Burdick,Noah L. Morales,Sabian A. Martinez,Isabella Law,Zachary J. Streblow,Daniel N. Streblow,Rafael M. Couñago,Nathaniel J. Moorman,Mark T. Heise,Timothy M. Willson	2025	0
3	More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication Journal of Medicinal Chemistry ·Han Wee Ong,Xuan Yang,Jeffery L. Smith,Rebekah J. Dickmander,Jason W. Brown,Tammy M. Havener,Sharon Taft-Benz,Stefanie Howell,Marcia K. Sanders,Jacob L. Capener,Rafael M. Couñago,Edcon Chang,Andreas Krämer,Nathaniel J. Moorman,Mark T. Heise,Alison D. Axtman,David H. Drewry,Timothy M. Willson	2024	6
4	Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2 Molecules ·Han Wee Ong,Xuan Yang,Jeffery L. Smith,Sharon Taft-Benz,Stefanie Howell,Rebekah J. Dickmander,Tammy M. Havener,Marcia K. Sanders,Jason W. Brown,Rafael M. Couñago,Edcon Chang,Andreas Krämer,Nathaniel J. Moorman,Mark T. Heise,Alison D. Axtman,David H. Drewry,Timothy M. Willson	2024	1
5	A novel BRET-based assay to investigate binding and residence time of unmodified ligands to the human lysosomal ion channel TRPML1 in intact cells Journal of Biological Chemistry ·Micael Rodrigues Cunha,Carolina Moura Costa Catta‐Preta,Jéssica E. Takarada,Gabriela A. Moreira,Katlin B. Massirer,Rafael M. Couñago	2023	2
6	An open source plant kinase chemogenomics set Plant Direct ·María Florencia Ercoli,Priscila Zonzini Ramos,Rashmi Jain,Joseph Pilotte,Oliver Xiaoou Dong,Ty Thompson,Carrow I. Wells,Jonathan M. Elkins,A.M. Edwards,Rafael M. Couñago,David H. Drewry,Pamela C. Ronald	2022	1
7	Discovery of novel benzothiophene derivatives as potent and narrow spectrum inhibitors of DYRK1A and DYRK1B Bioorganic & Medicinal Chemistry Letters ·N. Segretti,Jéssica E. Takarada,Marcos A. Ferreira,André da Silva Santiago,Bruno V. M. Teodoro,Mariana C.F.C.B. Damião,Paulo H. Godoi,Micael Rodrigues Cunha,M. Angela,Priscila Zonzini Ramos,Eloisa E. Ishikawa,Alessandra Mascarello,Ricardo A. M. Serafim,Hátylas Azevedo,Cristiano R. W. Guimarães,Rafael M. Couñago	2022	3
8	Identification of P218 as a potent inhibitor of Mycobacterium ulcerans DHFR RSC Medicinal Chemistry ·Gustavo Pelicioli Riboldi,Rachael Zigweid,Peter J. Myler,Stephen J. Mayclin,Rafael M. Couñago,Bart L. Staker	2020	6
9	Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major PLoS neglected tropical diseases ·Suélen Fernandes Silva,Angélica Hollunder Klippel,Priscila Zonzini Ramos,André da Silva Santiago,Sandro Roberto Valentini,Mário Henrique Bengtson,Katlin B. Massirer,Elizabeth Bilsland,Rafael M. Couñago,Cleslei Fernando Zanelli	2020	6
10	Binding and structural analyses of potent inhibitors of the human Ca2+/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available kinase inhibitors Scientific Reports ·Gerson S. Profeta,C.V. dos Reis,André da Silva Santiago,Paulo H. Godoi,M. Angela,Carrow I. Wells,Roger Sartori,Anita Salmazo,Priscila Zonzini Ramos,Katlin B. Massirer,Jonathan M. Elkins,David H. Drewry,O. Gileadi,Rafael M. Couñago	2019	15
11	SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K ACS Medicinal Chemistry Letters ·Carrow I. Wells,Rafael M. Couñago,Juanita C. Limas,Tuanny L. Almeida,Jeanette Gowen Cook,David H. Drewry,Jonathan M. Elkins,O. Gileadi,Nirav Kapadia,Álvaro Lorente‐Macías,Julie E. Pickett,Alexander J. Riemen,Roberta R. Ruela-de-Sousa,Timothy M. Willson,Cunyu Zhang,William J. Zuercher,Reena Zutshi,Alison D. Axtman	2019	28
12	Structural Analysis of Inhibitor Binding to CAMKK1 Identifies Features Necessary for Design of Specific Inhibitors Scientific Reports ·André da Silva Santiago,Rafael M. Couñago,Priscila Zonzini Ramos,Paulo H. Godoi,Katlin B. Massirer,O. Gileadi,Jonathan M. Elkins	2018	13
13	Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae Nature Communications ·Stephanie L. Neville,Bart A. Eijkelkamp,Zhenyao Luo,Rafael M. Couñago,Jacqueline R. Morey,Megan J. Maher,Cheryl‐lynn Y. Ong,Alastair G. McEwan,Boštjan Kobe,Megan L. O’Mara,James C. Paton,Christopher A. McDevitt	2015	100
14	Structures of Orf Virus Chemokine Binding Protein in Complex with Host Chemokines Reveal Clues to Broad Binding Specificity Structure ·Rafael M. Couñago,Karen Knapp,Yoshio Nakatani,Stephen B. Fleming,Michael Corbett,Lyn M. Wise,Andrew A. Mercer,Kurt L. Krause	2015	22
15	A glutathione-dependent detoxification system is required for formaldehyde resistance and optimal survival of Neisseria meningitidis in biofilms Queensland's institutional digital repository (The University of Queensland) ·Nathan H. Chen,Rafael M. Couñago,Karrera Y. Djoko,Michael P. Jennings,(unknown),Boštjan Kobe,Alastair G. McEwan	2013	1
16	Distinctive Conformation of Minor Site‐Specific Nuclear Localization Signals Bound to Importin‐α Traffic ·Chiung‐Wen Chang,Rafael M. Couñago,Simon J. Williams,Mikael Bodén,Boštjan Kobe	2013	44
17	A Glutathione-Dependent Detoxification System Is Required for Formaldehyde Resistance and Optimal Survival of Neisseria meningitidis in Biofilms Antioxidants and Redox Signaling ·Nathan H. Chen,Rafael M. Couñago,Karrera Y. Djoko,Michael P. Jennings,Michael A. Apicella,Boštjan Kobe,Alastair G. McEwan	2012	33
18	Prokaryotic Substrate-Binding Proteins as Targets for Antimicrobial Therapies Current Drug Targets ·Rafael M. Couñago,Christopher A. McDevitt,Miranda P. Ween,Boštjan Kobe	2012	32
19	Experimental Evolution of Adenylate Kinase Reveals Contrasting Strategies toward Protein Thermostability Biophysical Journal ·Corwin Miller,M.G. Davlieva,Corey J. Wilson,K. Ian White,Rafael M. Couñago,Gang Wu,Jeffrey C. Myers,Pernilla Wittung‐Stafshede,Yousif Shamoo	2010	23
20	An adaptive mutation in adenylate kinase that increases organismal fitness is linked to stability-activity trade-offs Protein Engineering Design and Selection ·Rafael M. Couñago,Corey J. Wilson,Marcia Ivonne Peña,Pernilla Wittung‐Stafshede,Yousif Shamoo	2007	34

About Rafael M. Couñago

Rafael M. Couñago is a scholar working on Horticulture, Molecular Medicine and Physiology, having authored 52 papers that have together received 1.1k indexed citations. Recurring topics across this work include Biochemical and Molecular Research (5 papers), Bacterial Genetics and Biotechnology (5 papers), Nuclear Structure and Function (4 papers), Cancer-related Molecular Pathways (4 papers), Enzyme Structure and Function (4 papers), Computational Drug Discovery Methods (4 papers), Antibiotic Resistance in Bacteria (4 papers) and Protein Structure and Dynamics (3 papers). The work is most often cited by research in Nutrition and Dietetics (179 citations), Molecular Medicine (55 citations) and Molecular Biology (630 citations). Rafael M. Couñago has collaborated with scholars based in Brazil, United States and Australia. Frequent co-authors include Boštjan Kobe, Yousif Shamoo, Christopher A. McDevitt, Alastair G. McEwan, Megan L. O’Mara, James C. Paton, Stephen S. Chen, Carlos G. Schrago, Márcio Alves‐Ferreira and C. Russo. Their work appears in journals such as Nucleic Acids Research, Journal of Biological Chemistry and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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