R M Bertina

10.2k citations

105 papers · 7.8k indexed · 3 hit papers · h-index 40

Impact in

Internal Medicine top 0.05%
- Venous Thromboembolism Diagnosis and Management
Hematology top 0.05%
- Blood Coagulation and Thrombosis Mechanisms
- Hemophilia Treatment and Research
- Platelet Disorders and Treatments

Papers in

Hematology 98
- Blood Coagulation and Thrombosis Mechanisms 85
- Hemophilia Treatment and Research 39
- Platelet Disorders and Treatments 17
Internal Medicine 17
- Venous Thromboembolism Diagnosis and Management 17

Co-authors: PH Reitsma FR Rosendaal Jan P. Vandenbroucke Ted Koster E Briët Hans de Ronde Frits R. Rosendaal P.H. Reitsma
Journals: Thrombosis and Haemostasis (28 papers)Blood (25 papers)Thrombosis Research (7 papers)Journal of Thrombosis and Haemostasis (6 papers)Blood Coagulation & Fibrinolysis (6 papers)
Partner nations: Netherlands United States Italy

In The Last Decade

R M Bertina

103 papers receiving 7.4k citations

Hit Papers

align trajectories log scale

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis 1996 · 2.4k citations

Peers

Countries citing papers authored by R M Bertina

Since Specialization

Citations

This map shows the geographic impact of R M Bertina's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by R M Bertina with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites R M Bertina more than expected).

Fields of papers citing papers by R M Bertina

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by R M Bertina. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by R M Bertina. The network helps show where R M Bertina may publish in the future.

Co-authors

The 25 scholars most cited alongside R M Bertina, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with R M Bertina Line = papers co-authored together R M Bertina links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Different effects of oral contraceptives containing different progestogens on protein S and tissue factor pathway inhibitor Journal of Thrombosis and Haemostasis ·Hubertus A.A.M. van Vliet, R M Bertina, Anders Erik Astrup Dahm, Frits R. Rosendaal, Jan Rosing, Per Morten Sandset, Frans M. Helmerhorst	2008	60
2	Haplotypes of the EPCR gene, prothrombin levels, and the risk of venous thrombosis in carriers of the prothrombin G20210A mutation Haematologica ·Silvia Navarro, Pilar Medina, Yolanda Mira, A. Estellés, Paola Villa, Fernando Ferrando, Amparo Vayá, R M Bertina, Francisco España	2008	43
3	Polymorphism 10034C>T is located in a region regulating polyadenylation of FGG transcripts and influences the fibrinogen γ′/γA mRNA ratio Journal of Thrombosis and Haemostasis ·Shirley Uitte de Willige, LT Rozendaal, Marieke C. Visser, Hans L. Vos, R M Bertina	2007	35
4	A new functional assay of thrombin activatable fibrinolysis inhibitor Journal of Thrombosis and Haemostasis ·Ana H.C. Guimarães, R M Bertina, D.C. RIJKEN	2005	18
5	Association between thrombin activatable fibrinolysis inhibitor genotype and levels in plasma: comparison of different assays British Journal of Haematology ·Ana H.C. Guimarães, Nico H. van Tilburg, Hans L. Vos, R M Bertina, D.C. Rijken	2004	39
6	Functional characterization of transcription factor binding sites for HNF1-alpha, HNF3-beta (FOXA2), HNF4-alpha, Sp1 and Sp3 in the human prothrombin gene enhancer Journal of Thrombosis and Haemostasis ·Эдуард Леонидович Архипов, Anita Kmari, Flávio Codeço Coelho, R M Bertina, Hans L. Vos	2003	23
7	Alterations in the extrinsic pathway in hypertriglyceridemia do not cause a ‘procoagulant state': effects of bezafibrate therapy Blood Coagulation & Fibrinolysis ·I.J.A.M. Jonkers, L. Frey, Nico H. van Tilburg, A. van der Laarse, Per Morten Sandset, A.H.M. Smelt, R M Bertina	2001	3
8	Careful selection of sample dilution and factor-V-deficient plasma makes the modified activated protein C resistance test highly specific for the factor V Leiden mutation Blood Coagulation & Fibrinolysis ·Hans de Ronde, R M Bertina	1999	15
9	Hereditary Prothrombin Deficiency Presenting as Intracranial Haematoma in Infancy Neuropediatrics ·Seon-Mi Park, S R Poort, W. O. Renier, F. Gabreëls, R M Bertina	1999	18
10	Three novel mutations in five unrelated subjects with hereditary protein S deficiency type I. Journal of Clinical Investigation ·Pieter H. Reitsma, Hans Kristian Ploos van Amstel, R M Bertina	1994	55
11	Expression of tissue factor and tissue factor pathway inhibitor in monocytes in response to bacterial lipopolysaccharide and phorbolester Blood Coagulation & Fibrinolysis ·罗韶伟, Richard Dirven, Pieter H. Reitsma, R M Bertina	1994	62
12	Homzygous Protein S Deficiency due to a One Base Pair Deletion that Leads to a Stop Codon in Exon III of the Protein S Gene Thrombosis and Haemostasis ·E. Gómez, Nayara Soares de Oliveira Lacerda, Charles H. Pegelow, P.H. Reitsma, R M Bertina	1994	40
13	Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study The Lancet ·Ted Koster, Jan P. Vandenbroucke, Suhani Mehta, Hans de Ronde, E Briët, R M Bertina Hit paper breakdown →	1993	990
14	Twelve novel and two recurrent mutations in 14 Austrian families with hereditary protein C deficiency Blood Coagulation & Fibrinolysis ·S R Poort, Ingrid Pabinger-Fasching, Christine Mannhalter, P H Reitsma, R M Bertina	1993	26
15	Activated protein C accelerates clot lysis by virtue of its anticoagulant activity Blood Coagulation & Fibrinolysis ·N.J. de Fouw, Nico H. van Tilburg, F. Haverkate, R M Bertina	1993	16
16	A CCA/CCG neutral dimorphism in the codon for Pro 626 of the human protein S gene PSα (PROS1) Nucleic Acids Research ·Aziz Moummou, Hans Kristian Ploos van Amstel, P.H. Reitsma, R M Bertina	1991	31
17	Protein C and Fibrinolysis: A Link between Coagulation and Fibrinolysis Advances in experimental medicine and biology ·N.J. de Fouw, F. Haverkate, R M Bertina	1990	22
18	Activated protein C decreases plasminogen activator-inhibitor activity in endothelial cell-conditioned medium Blood ·VW van Hinsbergh, R M Bertina, A van Wijngaarden, Dori Harcharik, J.J. Emeis, F. Haverkate	1985	256
19	Protein C values in coronary artery disease. BMJ ·N T O'Connor, A.W. Broekmans, R M Bertina	1984	14
20	Inhibition of tissue type plasminogen activator inhibitor activity by activated protein C: abstract Circulation ·R M Bertina, Victor W.M. van Hinsbergh, J.J. Emeis, A van Wijngaarden	1984	1

About R M Bertina

R M Bertina is a scholar working on Hematology, Internal Medicine, Genetics, Cancer Research and Critical Care and Intensive Care Medicine, having authored 105 papers that have together received 7.8k indexed citations. Recurring topics across this work include Blood Coagulation and Thrombosis Mechanisms (85 papers), Hemophilia Treatment and Research (39 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (20 papers), Platelet Disorders and Treatments (17 papers), Venous Thromboembolism Diagnosis and Management (17 papers), Blood properties and coagulation (15 papers), Cancer-related gene regulation (12 papers) and Protease and Inhibitor Mechanisms (9 papers). The work is most often cited by research in Internal Medicine (3.3k citations), Hematology (6.5k citations), Genetics (1.7k citations), Cardiology and Cardiovascular Medicine (1.9k citations) and Obstetrics and Gynecology (496 citations). R M Bertina has collaborated with scholars based in Netherlands, United States and Italy. Frequent co-authors include PH Reitsma, FR Rosendaal, Jan P. Vandenbroucke, Ted Koster, E Briët, Hans de Ronde, Frits R. Rosendaal, P.H. Reitsma, C.F. Allaart and F. Haverkate. Their work appears in journals such as Thrombosis and Haemostasis, Blood, Thrombosis Research, Journal of Thrombosis and Haemostasis and Blood Coagulation & Fibrinolysis.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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