Philip A. Leighton

5.4k total citations · 1 hit paper
46 papers, 3.3k citations indexed

About

Philip A. Leighton is a scholar working on Molecular Biology, Genetics and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Philip A. Leighton has authored 46 papers receiving a total of 3.3k indexed citations (citations by other indexed papers that have themselves been cited), including 30 papers in Molecular Biology, 21 papers in Genetics and 10 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Philip A. Leighton's work include Animal Genetics and Reproduction (15 papers), CRISPR and Genetic Engineering (11 papers) and Monoclonal and Polyclonal Antibodies Research (10 papers). Philip A. Leighton is often cited by papers focused on Animal Genetics and Reproduction (15 papers), CRISPR and Genetic Engineering (11 papers) and Monoclonal and Polyclonal Antibodies Research (10 papers). Philip A. Leighton collaborates with scholars based in United States, Germany and Chile. Philip A. Leighton's co-authors include Shirley M. Tilghman, Robert S. Ingram, Jonathan Eggenschwiler, Argiris Efstratiadis, Marie‐Cecile van de Lavoir, Jennifer Saam, Jeremy K. M. Sanders, R. J. Etches, S M Tilghman and Colin L. Stewart and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Philip A. Leighton

45 papers receiving 3.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Disruption of imprinting caused by deletion of the H19 gene region in mice

1995 627 citations Philip A. Leighton, Robert S. Ingram et al. Nature profile →

Peers

Philip A. Leighton

GENET

PPCH

CMN

Neil Vargesson United Kingdom

Christopher J. Ward United States

Yinghua Shen United States

Peggy S. Eis United States

Christopher S. Navara United States

W. J. Hage Netherlands

Joshua M. Brickman Denmark

Larry L. Deaven United States

James McGrath United States

Andrew E. H. Elia United States

Neil Vargesson United Kingdom

Philip A. Leighton

1.9k ×0.8

430 ×0.2

GENET

175 ×0.3

PPCH

152 ×0.6

CMN

408 ×1.9

Citations per year, relative to Philip A. Leighton Philip A. Leighton (= 1×) peers Neil Vargesson

Countries citing papers authored by Philip A. Leighton

Since Specialization

Citations

This map shows the geographic impact of Philip A. Leighton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philip A. Leighton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philip A. Leighton more than expected).

Fields of papers citing papers by Philip A. Leighton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philip A. Leighton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philip A. Leighton. The network helps show where Philip A. Leighton may publish in the future.

Co-authorship network of co-authors of Philip A. Leighton

This figure shows the co-authorship network connecting the top 25 collaborators of Philip A. Leighton. A scholar is included among the top collaborators of Philip A. Leighton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Philip A. Leighton. Philip A. Leighton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ching, Kathryn H., Darlene Pedersen, Alba T. Macias, et al.. (2021). Common light chain chickens produce human antibodies of high affinity and broad epitope coverage for the engineering of bispecifics. mAbs. 13(1). 1862451–1862451. 7 indexed citations

Cameron, Béatrice, Tarik Dabdoubi, F Soubrier, et al.. (2020). Complementary epitopes and favorable developability of monoclonal anti-LAMP1 antibodies generated using two transgenic animal platforms. PLoS ONE. 15(7). e0235815–e0235815. 6 indexed citations

Ching, Kathryn H., et al.. (2020). Expression of human lambda expands the repertoire of OmniChickens. PLoS ONE. 15(1). e0228164–e0228164. 5 indexed citations

Collarini, Ellen J., Philip A. Leighton, & Marie‐Cecile van de Lavoir. (2018). Production of Transgenic Chickens Using Cultured Primordial Germ Cells and Gonocytes. Methods in molecular biology. 1874. 403–430. 20 indexed citations

Leighton, Philip A., et al.. (2018). V(D)J Rearrangement Is Dispensable for Producing CDR-H3 Sequence Diversity in a Gene Converting Species. Frontiers in Immunology. 9. 1317–1317. 6 indexed citations

Dimitrov, Lazar, Darlene Pedersen, Kathryn H. Ching, et al.. (2016). Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells. PLoS ONE. 11(4). e0154303–e0154303. 84 indexed citations

Leighton, Philip A., Darlene Pedersen, Kathryn H. Ching, et al.. (2016). Generation of chickens expressing Cre recombinase. Transgenic Research. 25(5). 609–616. 11 indexed citations

Leighton, Philip A., et al.. (2015). A Diverse Repertoire of Human Immunoglobulin Variable Genes in a Chicken B Cell Line is Generated by Both Gene Conversion and Somatic Hypermutation. Frontiers in Immunology. 6. 126–126. 18 indexed citations

Schusser, Benjamin, Ellen J. Collarini, Shelley Izquierdo, et al.. (2013). Harnessing Gene Conversion in Chicken B Cells to Create a Human Antibody Sequence Repertoire. PLoS ONE. 8(11). e80108–e80108. 25 indexed citations

10.

Schusser, Benjamin, Ellen J. Collarini, Shelley Izquierdo, et al.. (2013). Immunoglobulin knockout chickens via efficient homologous recombination in primordial germ cells. Proceedings of the National Academy of Sciences. 110(50). 20170–20175. 122 indexed citations

11.

Lavoir, Marie‐Cecile van de, Ellen J. Collarini, Philip A. Leighton, et al.. (2012). Interspecific Germline Transmission of Cultured Primordial Germ Cells. PLoS ONE. 7(5). e35664–e35664. 57 indexed citations

12.

Leighton, Philip A., et al.. (2008). Genetic modification of primordial germ cells by gene trapping, gene targeting, and ϕC31 integrase. Molecular Reproduction and Development. 75(7). 1163–1175. 50 indexed citations

13.

Lavoir, Marie‐Cecile van de, Philip A. Leighton, Babette S. Heyer, et al.. (2006). Germline transmission of genetically modified primordial germ cells. Nature. 441(7094). 766–769. 355 indexed citations

14.

Lavoir, Marie‐Cecile van de, Philip A. Leighton, Babette S. Heyer, et al.. (2005). High-grade transgenic somatic chimeras from chicken embryonic stem cells. Mechanisms of Development. 123(1). 31–41. 86 indexed citations

15.

Leighton, Philip A., Kevin J. Mitchell, Lisa V. Goodrich, et al.. (2001). Defining brain wiring patterns and mechanisms through gene trapping in mice. Nature. 410(6825). 174–179. 338 indexed citations

16.

Mitchell, Kevin J., Olivia Kelly, Jane Brennan, et al.. (2001). Functional analysis of secreted and transmembrane proteins critical to mouse development. Nature Genetics. 28(3). 241–249. 341 indexed citations

17.

Eggenschwiler, Jonathan, Thomas Ludwig, Peter Fisher, et al.. (1997). Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith–Wiedemann and Simpson–Golabi–Behmel syndromes. Genes & Development. 11(23). 3128–3142. 270 indexed citations

18.

Leighton, Philip A., Jennifer Saam, Robert S. Ingram, & Shirley M. Tilghman. (1996). Genomic Imprinting in Mice: Its Function and Mechanism1. Biology of Reproduction. 54(2). 273–278. 45 indexed citations

19.

Tilghman, S M, Marisa S. Bartolomei, Andrea L. Webber, et al.. (1993). Parental Imprinting of the H19 and Igf2 Genes in the Mouse. Cold Spring Harbor Symposia on Quantitative Biology. 58(0). 287–295. 19 indexed citations

20.

Leighton, Philip A. & Pei‐Hua Lu. (1987). .lambda. cro Repressor complex with OR3 DNA: nitrogen-15 NMR observations. Biochemistry. 26(23). 7262–7271. 30 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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