Phang‐Lang Chen

14.3k total citations · 6 hit papers
100 papers, 11.9k citations indexed

About

Phang‐Lang Chen is a scholar working on Molecular Biology, Oncology and Genetics. According to data from OpenAlex, Phang‐Lang Chen has authored 100 papers receiving a total of 11.9k indexed citations (citations by other indexed papers that have themselves been cited), including 74 papers in Molecular Biology, 46 papers in Oncology and 28 papers in Genetics. Recurrent topics in Phang‐Lang Chen's work include Cancer-related Molecular Pathways (41 papers), DNA Repair Mechanisms (33 papers) and BRCA gene mutations in cancer (14 papers). Phang‐Lang Chen is often cited by papers focused on Cancer-related Molecular Pathways (41 papers), DNA Repair Mechanisms (33 papers) and BRCA gene mutations in cancer (14 papers). Phang‐Lang Chen collaborates with scholars based in United States, Taiwan and China. Phang‐Lang Chen's co-authors include Wen‐Hwa Lee, Yumay Chen, Chi‐Fen Chen, Jin‐Yuh Shew, Robert Bookstein, W H Lee, Peter Scully, T. Durfee, Yijing Yang and Z. Dave Sharp and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Phang‐Lang Chen

99 papers receiving 11.7k citations

Hit Papers

The retinoblastoma protein associates with the protein ph... 1988 2026 2000 2013 1993 1989 1988 2002 1990 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.
    1993 1.3k citations Phang‐Lang Chen et al. profile →
  2. Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation
    1989 852 citations Phang‐Lang Chen, Jin‐Yuh Shew et al. profile →
  3. Suppression of the Neoplastic Phenotype by Replacement of the RB Gene in Human Cancer Cells
    1988 680 citations Jin‐Yuh Shew, Phang‐Lang Chen et al. Science profile →
  4. BRCA2 Function in DNA Binding and Recombination from a BRCA2-DSS1-ssDNA Structure
    2002 549 citations Haijuan Yang, Philip D. Jeffrey et al. Science profile →
  5. Suppression of Tumorigenicity of Human Prostate Carcinoma Cells by Replacing a Mutated RB Gene
    1990 523 citations Robert Bookstein, Jin‐Yuh Shew et al. Science profile →
  6. Association of BRCA1 with the hRad50-hMre11-p95 Complex and the DNA Damage Response
    1999 513 citations Qing Zhong, Chi‐Fen Chen et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Phang‐Lang Chen United States 53 9.2k 4.5k 3.0k 1.6k 1.4k 100 11.9k
Jacqueline A. Lees United States 53 9.2k 1.0× 5.7k 1.3× 2.5k 0.8× 1.2k 0.7× 1.7k 1.2× 101 12.3k
John K. Cowell United States 57 7.0k 0.8× 2.2k 0.5× 1.9k 0.6× 1.6k 1.0× 1.6k 1.1× 302 11.3k
Douglas C. Dean United States 54 8.4k 0.9× 4.6k 1.0× 1.2k 0.4× 1.3k 0.8× 1.9k 1.3× 107 11.9k
Brian David Dynlacht United States 63 13.0k 1.4× 4.6k 1.0× 3.5k 1.2× 3.7k 2.2× 1.3k 0.9× 107 15.8k
Mark E. Ewen United States 38 7.1k 0.8× 6.7k 1.5× 1.9k 0.6× 1.4k 0.9× 1.1k 0.8× 54 10.4k
Jean Y. J. Wang United States 56 8.3k 0.9× 4.5k 1.0× 886 0.3× 1.4k 0.9× 1.2k 0.8× 127 11.6k
Philip W. Hinds United States 47 7.2k 0.8× 7.2k 1.6× 1.4k 0.5× 1.1k 0.7× 2.0k 1.4× 107 11.8k
Hein te Riele Netherlands 44 6.0k 0.7× 2.3k 0.5× 1.5k 0.5× 550 0.3× 1.3k 0.9× 108 8.2k
Jiřina Bártková Denmark 62 10.5k 1.1× 7.8k 1.7× 1.8k 0.6× 2.0k 1.2× 2.8k 2.0× 136 15.4k
Andrew Koff United States 53 10.2k 1.1× 8.7k 1.9× 1.2k 0.4× 2.2k 1.4× 2.0k 1.4× 103 15.0k

Countries citing papers authored by Phang‐Lang Chen

Since Specialization
Citations

This map shows the geographic impact of Phang‐Lang Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Phang‐Lang Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Phang‐Lang Chen more than expected).

Fields of papers citing papers by Phang‐Lang Chen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Phang‐Lang Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Phang‐Lang Chen. The network helps show where Phang‐Lang Chen may publish in the future.

Co-authorship network of co-authors of Phang‐Lang Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Phang‐Lang Chen. A scholar is included among the top collaborators of Phang‐Lang Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Phang‐Lang Chen. Phang‐Lang Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Chen, Phang‐Lang, Chi‐Fen Chen, Hugo You‐Hsien Lin, Daniel Riley, & Yumay Chen. (2024). The Link between Autosomal Dominant Polycystic Kidney Disease and Chromosomal Instability: Exploring the Relationship. International Journal of Molecular Sciences. 25(5). 2936–2936. 2 indexed citations
2.
Lin, Hugo You‐Hsien, Phang‐Lang Chen, Sheng‐Wen Niu, et al.. (2024). The application of blood flow sound contrastive learning to predict arteriovenous graft stenosis of patients with hemodialysis. PLoS ONE. 19(8). e0308385–e0308385.
3.
Chen, Yuhan, Yumay Chen, Wenjun Fan, et al.. (2023). Dual roles of myocardial mitochondrial AKT on diabetic cardiomyopathy and whole body metabolism. Cardiovascular Diabetology. 22(1). 294–294. 10 indexed citations
4.
Yu, Huan, Phang‐Lang Chen, Yuqing Zhao, et al.. (2015). Effect of sphingosine-1-phosphate and myoblast transplantation on rat acute myocardial infarction. Genetics and Molecular Research. 14(4). 13843–13851. 3 indexed citations
5.
Chen, Yumay, Chi‐Fen Chen, Rosaria Polci, et al.. (2014). Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment. Oncotarget. 5(12). 4283–4294. 21 indexed citations
6.
Zhu, Jiewen, Longen Zhou, Guikai Wu, et al.. (2013). A novel small molecule RAD51 inactivator overcomes imatinib‐resistance in chronic myeloid leukaemia. EMBO Molecular Medicine. 5(3). 353–365. 74 indexed citations
7.
Wei, Pei‐Chi, Yi‐Hsuan Hsieh, Xianzhi Jiang, et al.. (2012). Loss of the Oxidative Stress Sensor NPGPx Compromises GRP78 Chaperone Activity and Induces Systemic Disease. Molecular Cell. 48(5). 747–759. 124 indexed citations
8.
Chen, Yumay, Chi‐Fen Chen, Daniel Riley, & Phang‐Lang Chen. (2011). Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR. Cell Cycle. 10(4). 655–663. 63 indexed citations
9.
Wu, Guikai, Xiaolong Qiu, Longen Zhou, et al.. (2008). Small Molecule Targeting the Hec1/Nek2 Mitotic Pathway Suppresses Tumor Cell Growth in Culture and in Animal. Cancer Research. 68(20). 8393–8399. 92 indexed citations
10.
Chen, Phang‐Lang, et al.. (2003). NFBD1, a Novel Nuclear Protein with Signature Motifs of FHA and BRCT, and an Internal 41-Amino Acid Repeat Sequence, Is an Early Participant in DNA Damage Response. Journal of Biological Chemistry. 278(8). 6323–6329. 71 indexed citations
11.
Peng, Aimin & Phang‐Lang Chen. (2003). NFBD1, Like 53BP1, Is an Early and Redundant Transducer Mediating Chk2 Phosphorylation in Response to DNA Damage. Journal of Biological Chemistry. 278(11). 8873–8876. 86 indexed citations
12.
Yang, Haijuan, Philip D. Jeffrey, Julie J. Miller, et al.. (2002). BRCA2 Function in DNA Binding and Recombination from a BRCA2-DSS1-ssDNA Structure. Science. 297(5588). 1837–1848. 549 indexed citations breakdown →
13.
Chen, Yumay, Daniel Riley, Phang‐Lang Chen, & Wen‐Hwa Lee. (1997). HEC, a Novel Nuclear Protein Rich in Leucine Heptad Repeats Specifically Involved in Mitosis. Molecular and Cellular Biology. 17(10). 6049–6056. 114 indexed citations
14.
Zhong, Qing, Chi‐Fen Chen, Yuan Chen, Phang‐Lang Chen, & Wen‐Hwa Lee. (1997). Identification of cellular TSG101 protein in multiple human breast cancer cell lines.. PubMed. 57(19). 4225–8. 19 indexed citations
15.
Chen, Chi‐Fen, Yumay Chen, Kang Dai, et al.. (1996). A New Member of the hsp90 Family of Molecular Chaperones Interacts with the Retinoblastoma Protein during Mitosis and after Heat Shock. Molecular and Cellular Biology. 16(9). 4691–4699. 154 indexed citations
16.
Chen, Yumay, Phang‐Lang Chen, & Wen‐Hwa Lee. (1994). Hot-Spot p53 Mutants Interact Specifically with Two Cellular Proteins during Progression of the Cell Cycle. Molecular and Cellular Biology. 14(10). 6764–6772. 4 indexed citations
17.
Hsu, Wei, Tom K. Kerppola, Phang‐Lang Chen, Tom Curran, & Selina Chen‐Kiang. (1994). Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region.. Molecular and Cellular Biology. 14(1). 268–276. 182 indexed citations
18.
Hollingsworth, Robert E., et al.. (1991). RB Protein as a Cellular "Corral" for Growth-promoting Proteins. Cold Spring Harbor Symposia on Quantitative Biology. 56(0). 211–217. 30 indexed citations
19.
Chen, Phang‐Lang, et al.. (1990). DNA-binding activity of retinoblastoma protein is intrinsic to its carboxyl-terminal region.. PubMed. 1(5). 233–9. 34 indexed citations
20.
Shew, Jin‐Yuh, et al.. (1990). Deletion of a splice donor site ablates expression of the following exon and produces an unphosphorylated RB protein unable to bind SV40 T antigen.. PubMed. 1(1). 17–25. 51 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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