Paul LaPointe

2.4k citations

35 papers · 1.9k indexed · h-index 16

Impact in

Cell Biology top 2%
- Cellular transport and secretion
- Endoplasmic Reticulum Stress and Disease
Molecular Biology top 5%
- Heat shock proteins research
- RNA Research and Splicing
- Protein Structure and Dynamics
- Lipid Membrane Structure and Behavior

Papers in ⓘ

Cell Biology 9
- Endoplasmic Reticulum Stress and Disease 6
- Cellular transport and secretion 5
Molecular Biology 31
- Heat shock proteins research 19
- ATP Synthase and ATPases Research 7
- Protein Structure and Dynamics 7
- RNA Research and Splicing 4
- RNA and protein synthesis mechanisms 3

Co-authors: William E. Balch (9 shared papers)Cemal Gürkan (6 shared papers)Scott M. Stagg (5 shared papers)Bridget Carragher (3 shared papers)Clinton S. Potter (3 shared papers)Jeanne Matteson (2 shared papers)John R. Yates (2 shared papers)Atanas V. Koulov (2 shared papers)
Journals: Molecular Biology of the Cell (3 papers)Nature Communications (2 papers)Nature Structural & Molecular Biology (2 papers)Cell (2 papers)Journal of Biological Chemistry (2 papers)
Partner nations: Canada United States Cyprus

In The Last Decade

Paul LaPointe

35 papers receiving 1.8k citations

Peers

Countries citing papers authored by Paul LaPointe

Since Specialization

Citations

This map shows the geographic impact of Paul LaPointe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul LaPointe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul LaPointe more than expected).

Fields of papers citing papers by Paul LaPointe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul LaPointe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul LaPointe. The network helps show where Paul LaPointe may publish in the future.

Co-authors

The 25 scholars most cited alongside Paul LaPointe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Paul LaPointe Line = papers co-authored together Paul LaPointe links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 35 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis Cell ·Xiaodong Wang, John D. Venable, Paul LaPointe, Darren M. Hutt, Atanas V. Koulov, Judith A. Coppinger, Cemal Gürkan, Wendy A. Kellner, Jeanne Matteson, Helen Plutner, John R. Riordan, Jeffery W. Kelly, John R. Yates, William E. Balch	2006	493
2	Structure of the Sec13/31 COPII coat cage Nature ·Scott M. Stagg, Cemal Gürkan, Douglas M. Fowler, Paul LaPointe, Ted R. Foss, Clinton S. Potter, Bridget Carragher, William E. Balch	2006	259
3	Structural Basis for Cargo Regulation of COPII Coat Assembly Cell ·Scott M. Stagg, Paul LaPointe, Abbas Razvi, Cemal Gürkan, Clinton S. Potter, Bridget Carragher, William E. Balch	2008	204
4	The COPII cage: unifying principles of vesicle coat assembly Nature Reviews Molecular Cell Biology ·Cemal Gürkan, Scott M. Stagg, Paul LaPointe, William E. Balch	2006	168
5	Biological and Structural Basis for Aha1 Regulation of Hsp90 ATPase Activity in Maintaining Proteostasis in the Human Disease Cystic Fibrosis Molecular Biology of the Cell ·Atanas V. Koulov, Paul LaPointe, Bingwen Lu, Abbas Razvi, Judith A. Coppinger, Meng‐Qiu Dong, Jeanne Matteson, Rob C. Laister, C.H. Arrowsmith, John R. Yates, William E. Balch	2010	137
6	Hsp90 Regulates the Function of Argonaute 2 and Its Recruitment to Stress Granules and P-Bodies Molecular Biology of the Cell ·Justin M. Pare, Nasser Tahbaz, Joaquín López-Orozco, Paul LaPointe, Paul Lasko, Tom C. Hobman	2009	120
7	Structural design of cage and coat scaffolds that direct membrane traffic Current Opinion in Structural Biology ·Scott M. Stagg, Paul LaPointe, William E. Balch	2007	61
8	The Mechanism of Hsp90 ATPase Stimulation by Aha1 Scientific Reports ·Annemarie Wolmarans, Brian Lee, Leo Spyracopoulos, Paul LaPointe	2016	52
9	A Role for the Protease-sensitive Loop Region of Shiga-like Toxin 1 in the Retrotranslocation of Its A1 Domain from the Endoplasmic Reticulum Lumen Journal of Biological Chemistry ·Paul LaPointe, Xin Wei, Jean Gariépy	2005	48
10	The ER chaperone calnexin controls mitochondrial positioning and respiration Science Signaling ·Tomás Gutiérrez, Hong Qi, Megan C. Yap, Nasser Tahbaz, Leanne Milburn, Eliana Lucchinetti, Phing‐How Lou, Michael Zaugg, Paul LaPointe, Pascal Mercier, Michael Overduin, Helmut Bischof, Sandra Burgstaller, Roland Malli, Klaus Ballanyi, Jianwei Shuai, Thomas Simmen	2020	40
11	An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humans Nature Communications ·Abbey D. Zuehlke, Michael Reidy, Coney P. C. Lin, Paul LaPointe, Sarah Alsomairy, D. Joshua Lee, Génesis M. Rivera-Márquez, Kristin Beebe, Thomas L. Prince, Sunmin Lee, Jane B. Trepel, Wanping Xu, Jill L. Johnson, Daniel C. Masison, Len Neckers	2017	33
12	Hsp90 cochaperones p23 and FKBP4 physically interact with hAgo2 and activate RNA interference–mediated silencing in mammalian cells Molecular Biology of the Cell ·Justin M. Pare, Paul LaPointe, Tom C. Hobman	2013	33
13	A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation Nature Structural & Molecular Biology ·Matthew J. Schellenberg, Tao Wu, Dustin B. Ritchie, Sebastian M. Fica, Jonathan P. Staley, Karim A Atta, Paul LaPointe, Andrew M. MacMillan	2013	30
14	The Co-Chaperone Hch1 Regulates Hsp90 Function Differently than Its Homologue Aha1 and Confers Sensitivity to Yeast to the Hsp90 Inhibitor NVP-AUY922 PLoS ONE ·Heather Armstrong, Annemarie Wolmarans, Rebecca Mercier, BaoChan Mai, Paul LaPointe	2012	27
15	The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation Nature Communications ·Rebecca Mercier, Annemarie Wolmarans, Jonathan Schubert, Hannes Neuweiler, Jill L. Johnson, Paul LaPointe	2019	24
16	A Mutation in the Catalytic Loop of Hsp90 Specifically Impairs ATPase Stimulation by Aha1p, But Not Hch1p Journal of Molecular Biology ·Natalie K. Horvat, Heather Armstrong, Brian L. Lee, Rebecca Mercier, Annemarie Wolmarans, J.A. Knowles, Leo Spyracopoulos, Paul LaPointe	2014	19
17	Mise en Place–This Bud's for the Golgi Molecular Cell ·Paul LaPointe, Cemal Gürkan, William E. Balch	2004	12
18	Fluorine- and rhenium-containing geldanamycin derivatives as leads for the development of molecular probes for imaging Hsp90 Organic & Biomolecular Chemistry ·Frank Wuest, Vincent Bouvet, BaoChan Mai, Paul LaPointe	2012	12
19	Regulation of RNA interference by Hsp90 is an evolutionarily conserved process Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Yang Wang, Rebecca Mercier, Tom C. Hobman, Paul LaPointe	2013	11
20	The role of cellular proteostasis in antitumor immunity Journal of Biological Chemistry ·Rebecca Mercier, Paul LaPointe	2022	11

About Paul LaPointe

Paul LaPointe is a scholar working on Cell Biology, Molecular Biology, Materials Chemistry, Immunology and Physical and Theoretical Chemistry, having authored 35 papers that have together received 1.9k indexed citations. Recurring topics across this work include Heat shock proteins research (19 papers), Enzyme Structure and Function (8 papers), ATP Synthase and ATPases Research (7 papers), Protein Structure and Dynamics (7 papers), Endoplasmic Reticulum Stress and Disease (6 papers), Cellular transport and secretion (5 papers), RNA Research and Splicing (4 papers) and RNA and protein synthesis mechanisms (3 papers). The work is most often cited by research in Cell Biology (731 citations), Molecular Biology (1.4k citations), Structural Biology (23 citations), Aging (27 citations) and Endocrinology (38 citations). Paul LaPointe has collaborated with scholars based in Canada, United States and Cyprus. Frequent co-authors include William E. Balch, Cemal Gürkan, Scott M. Stagg, Bridget Carragher, Clinton S. Potter, Jeanne Matteson, John R. Yates, Atanas V. Koulov, Judith A. Coppinger and Abbas Razvi. Their work appears in journals such as Molecular Biology of the Cell, Nature Communications, Nature Structural & Molecular Biology, Cell and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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