Paul deRoos

8.4k total citations · 3 hit papers
31 papers, 6.6k citations indexed

About

Paul deRoos is a scholar working on Immunology, Molecular Biology and Nutrition and Dietetics. According to data from OpenAlex, Paul deRoos has authored 31 papers receiving a total of 6.6k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Immunology, 7 papers in Molecular Biology and 6 papers in Nutrition and Dietetics. Recurrent topics in Paul deRoos's work include Immune Cell Function and Interaction (14 papers), T-cell and B-cell Immunology (14 papers) and Immunotherapy and Immune Responses (11 papers). Paul deRoos is often cited by papers focused on Immune Cell Function and Interaction (14 papers), T-cell and B-cell Immunology (14 papers) and Immunotherapy and Immune Responses (11 papers). Paul deRoos collaborates with scholars based in United States, Italy and South Africa. Paul deRoos's co-authors include Alexander Y. Rudensky, Stanislav Dikiy, Paul J. Coffer, Nicholas Arpaia, Justin R. Cross, Klaus Pfeffer, Xiying Fan, Hui Liu, Clarissa Campbell and Joris van der Veeken and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Paul deRoos

28 papers receiving 6.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

2013 3.5k citations Nicholas Arpaia, Clarissa Campbell et al. Nature profile →
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

2009 735 citations Ye Zheng, Ashutosh Chaudhry et al. Nature profile →
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

2006 640 citations Marc A. Gavin, Troy R. Torgerson et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Paul deRoos United States	17	3.2k	3.1k	916	756	696	31	6.6k
Santhakumar Manicassamy United States	32	2.9k 0.9×	3.1k 1.0×	676 0.7×	545 0.7×	858 1.2×	55	6.3k
J. Rodrigo Mora United States	28	4.5k 1.4×	2.1k 0.7×	579 0.6×	896 1.2×	569 0.8×	45	7.7k
Xiying Fan United States	15	2.6k 0.8×	2.9k 0.9×	969 1.1×	759 1.0×	565 0.8×	17	6.0k
Joris van der Veeken United States	19	1.8k 0.5×	3.0k 1.0×	824 0.9×	727 1.0×	602 0.9×	22	5.1k
Craig L. Maynard United States	21	2.6k 0.8×	2.0k 0.7×	588 0.6×	706 0.9×	510 0.7×	36	5.3k
Stanislav Dikiy United States	12	2.2k 0.7×	2.8k 0.9×	872 1.0×	771 1.0×	478 0.7×	15	5.3k
Jason A. Hall United States	19	5.5k 1.7×	2.3k 0.8×	573 0.6×	701 0.9×	574 0.8×	26	8.2k
Michael S. Rolph Australia	27	2.1k 0.7×	2.5k 0.8×	1.4k 1.5×	839 1.1×	405 0.6×	43	5.9k
Frédéric Sierro Australia	23	1.6k 0.5×	2.3k 0.8×	845 0.9×	517 0.7×	639 0.9×	32	4.8k
Nicolas Bouladoux United States	35	4.8k 1.5×	2.2k 0.7×	625 0.7×	940 1.2×	562 0.8×	52	8.1k

Countries citing papers authored by Paul deRoos

Since Specialization

Citations

This map shows the geographic impact of Paul deRoos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul deRoos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul deRoos more than expected).

Fields of papers citing papers by Paul deRoos

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul deRoos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul deRoos. The network helps show where Paul deRoos may publish in the future.

Co-authorship network of co-authors of Paul deRoos

This figure shows the co-authorship network connecting the top 25 collaborators of Paul deRoos. A scholar is included among the top collaborators of Paul deRoos based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul deRoos. Paul deRoos is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Cooper, Kirsten, Dante Acenas, Anastasia I. Kousa, et al.. (2025). Damage-induced IL-18 stimulates thymic NK cells limiting endogenous tissue regeneration. Nature Immunology. 26(10). 1699–1711.

Cooper, Kirsten, Dante Acenas, Lorenzo Iovino, et al.. (2023). Hematopoietic Stem Cell Transplantation (HCT) Conditioning Leads to NK Cell Cytotoxicity Limiting Endogenous Thymus Regeneration. Blood. 142(Supplement 1). 461–461.

Iovino, Lorenzo, Kirsten Cooper, Paul deRoos, et al.. (2022). Activation of the zinc-sensing receptor GPR39 promotes T-cell reconstitution after hematopoietic cell transplant in mice. Blood. 139(25). 3655–3666. 20 indexed citations

Kinsella, Sinéad, Kirsten Cooper, Lorenzo Iovino, et al.. (2021). Attenuation of apoptotic cell detection triggers thymic regeneration after damage. Cell Reports. 37(1). 109789–109789. 11 indexed citations

Iovino, Lorenzo, Sinéad Kinsella, Kirsten Cooper, et al.. (2020). Thymic Reconstitution after Damage Is Influenced By Zinc Status. Biology of Blood and Marrow Transplantation. 26(3). S304–S305. 2 indexed citations

Iovino, Lorenzo, Kirsten Cooper, Sinéad Kinsella, et al.. (2019). Zinc Improves Thymic Regeneration after Allogeneic HSCT By Stimulating BMP4 Production from Endothelial Cells. Biology of Blood and Marrow Transplantation. 25(3). S333–S333. 1 indexed citations

Iovino, Lorenzo, Sinéad Kinsella, Kirsten Cooper, et al.. (2019). Zinc Treatment Stimulates Thymic Regeneration after Bone Marrow Transplant. Blood. 134(Supplement_1). 4422–4422. 4 indexed citations

Kinsella, Sinéad, Kirsten Cooper, Lorenzo Iovino, et al.. (2019). Homeostatic Regulation of Apoptosis Governs Thymus Regeneration. Blood. 134(Supplement_1). 587–587. 1 indexed citations

Arpaia, Nicholas, Clarissa Campbell, Xiying Fan, et al.. (2013). Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation. Nature. 504(7480). 451–455. 3510 indexed citations breakdown →

10.

Rudra, Dipayan, Paul deRoos, Ashutosh Chaudhry, et al.. (2012). Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nature Immunology. 13(10). 1010–1019. 344 indexed citations

11.

Kim, Jeong, Katharina Lahl, Shohei Hori, et al.. (2009). Cutting Edge: Depletion of Foxp3+ Cells Leads to Induction of Autoimmunity by Specific Ablation of Regulatory T Cells in Genetically Targeted Mice. The Journal of Immunology. 183(12). 7631–7634. 137 indexed citations

12.

Zheng, Ye, Ashutosh Chaudhry, Arnold Kas, et al.. (2009). Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses. Nature. 458(7236). 351–356. 735 indexed citations breakdown →

13.

Gavin, Marc A., Troy R. Torgerson, Evan Houston, et al.. (2006). Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proceedings of the National Academy of Sciences. 103(17). 6659–6664. 640 indexed citations breakdown →

14.

Hsieh, Chyi‐Song, Paul deRoos, Karen Honey, Courtney Beers, & Alexander Y. Rudensky. (2002). A Role for Cathepsin L and Cathepsin S in Peptide Generation for MHC Class II Presentation. The Journal of Immunology. 168(6). 2618–2625. 144 indexed citations

15.

Dongre, Ashok, Susan Kovats, Paul deRoos, et al.. (2001). In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses. European Journal of Immunology. 31(5). 1485–1494. 141 indexed citations

16.

Grubin, C. E., Susan Kovats, Paul deRoos, & Alexander Y. Rudensky. (1997). Deficient Positive Selection of CD4 T Cells in Mice Displaying Altered Repertoires of MHC Class II–Bound Self-Peptides. Immunity. 7(2). 197–208. 189 indexed citations

17.

Eastman, Susan, Michael Deftos, Paul deRoos, et al.. (1996). A study of complexes of class II invariant chain peptide: Major histocompatibility complex class II molecules using a new complex‐specific monoclonal antibody. European Journal of Immunology. 26(2). 385–393. 54 indexed citations

18.

Farr, Andrew G., Paul deRoos, Susan Eastman, & Alexander Y. Rudensky. (1996). Differential expression of CLIP: MHC class II and conventional endogenous peptide: MHC class II complexes by thymic epithelial cells and peripheral antigen‐presenting cells. European Journal of Immunology. 26(12). 3185–3193. 29 indexed citations

19.

Rudensky, Alexander Y., et al.. (1994). Intracellular assembly and transport of endogenous peptide-MHC class II complexes. Immunity. 1(7). 585–594. 95 indexed citations

20.

Curtis, Benson M., M B Widmer, Paul deRoos, & Eva E. Qwarnström. (1990). IL-1 and its receptor are translocated to the nucleus.. The Journal of Immunology. 144(4). 1295–1303. 158 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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