Özlen Güzel-Akdemir

1.1k citations

41 papers · 951 indexed · h-index 20

Organic Chemistry top 2%
- Synthesis and Catalytic Reactions 19
- Synthesis and biological activity 14
- Synthesis and Biological Evaluation 6
- Synthesis and Characterization of Heterocyclic Compounds 5
Physical and Theoretical Chemistry top 5%
Pharmacology top 5%
- Cholinesterase and Neurodegenerative Diseases 7
Molecular Biology
- Enzyme function and inhibition 24
- Phenothiazines and Benzothiazines Synthesis and Activities 15
- Cancer therapeutics and mechanisms 5
Toxicology top 10%

Co-authors: Aydın Salman Claudiu T. Supuran Nilgün Karalı Andrea Scozzafava Atilla Akdemir Alessio Innocenti Süheyla Özbey Nurten Özsoy
Cited by: Organic Chemistry Physical and Theoretical Chemistry Pharmacology
Journals: International Journal of Molecular Sciences (3 papers)Journal of Medicinal Chemistry (2 papers)European Journal of Medicinal Chemistry (1 paper)
Partner nations: Türkiye Italy United States

In The Last Decade

Özlen Güzel-Akdemir

40 papers receiving 922 citations

Peers

Countries citing papers authored by Özlen Güzel-Akdemir

Since Specialization

Citations

This map shows the geographic impact of Özlen Güzel-Akdemir's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Özlen Güzel-Akdemir with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Özlen Güzel-Akdemir more than expected).

Fields of papers citing papers by Özlen Güzel-Akdemir

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Özlen Güzel-Akdemir. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Özlen Güzel-Akdemir. The network helps show where Özlen Güzel-Akdemir may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Özlen Güzel-Akdemir, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Özlen Güzel-Akdemir Line = papers co-authored together Özlen Güzel-Akdemir links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Novel 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide based thiosemicarbazides as potent and selective inhibitors of tumor-associated human carbonic anhydrase IX and XII: Synthesis, cytotoxicity, and molecular modelling studies Bioorganic Chemistry ·Kübra Demir-Yazıcı,Muhammed Trawally,Silvia Bua,Dilek Öztürk-Civelek,Atilla Akdemir,Claudiu T. Supuran,Özlen Güzel-Akdemir	2024	6
2	Thiosemicarbazone-benzenesulfonamide Derivatives as Human Carbonic AnhydrasesInhibitors: Synthesis, Characterization, and In silico Studies Anti-Cancer Agents in Medicinal Chemistry ·Muhammed Trawally,Kübra Demir-Yazıcı,Andrea Angeli,Kerem Kaya,Atilla Akdemir,Claudiu T. Supuran,Özlen Güzel-Akdemir,(unknown)	2024	4
3	Urease inhibitors for the treatment of H. pylori Expert Opinion on Therapeutic Patents ·Özlen Güzel-Akdemir,Atilla Akdemir	2024	4
4	Dithiocarbamates and dithiocarbonates containing 6-nitrosaccharin scaffold: Synthesis, antimycobacterial activity and in silico target prediction using ensemble docking-based reverse virtual screening Journal of Molecular Structure ·Muhammed Trawally,Kübra Demir-Yazıcı,Serap İpek Dingiş-Birgül,Kerem Kaya,Atilla Akdemir,Özlen Güzel-Akdemir	2022	5
5	Mandelic acid-based spirothiazolidinones targeting M. tuberculosis: Synthesis, in vitro and in silico investigations Bioorganic Chemistry ·Muhammed Trawally,Kübra Demir-Yazıcı,Serap İpek Dingiş-Birgül,Kerem Kaya,Atilla Akdemir,Özlen Güzel-Akdemir	2022	8
6	Synthesis and antibacterial activity of new hybrid derivatives of 5-sulfamoyl-1H-indole and 4-thiazolidinone groups Monatshefte für Chemie - Chemical Monthly ·Özlen Güzel-Akdemir,Muhammed Trawally,Mehtap Özbek-Babuç,Berna Özbek Çelık,Görkem Ermut,Hakan Özdemir	2020	6
7	Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII Bioorganic Chemistry ·Süleyman Akocak,Özlen Güzel-Akdemir,Rajesh Kishore Kumar Sanku,Samson S. Russom,Bogdan I. Iorga,Claudiu T. Supuran,Marc A. Ilies	2020	29
8	Isatin analogs as novel inhibitors of Candida spp. β-carbonic anhydrase enzymes Bioorganic & Medicinal Chemistry ·Atilla Akdemir,Özlen Güzel-Akdemir,Nilgün Karalı,Claudiu T. Supuran	2016	24
9	Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides Bioorganic & Medicinal Chemistry ·Atilla Akdemir,Özlen Güzel-Akdemir,Andrea Scozzafava,Clemente Capasso,Claudiu T. Supuran	2013	22
10	Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition Bioorganic & Medicinal Chemistry ·Özlen Güzel-Akdemir,Shyamasri Biswas,Katherine Lastra,Robert McKenna,Claudiu T. Supuran	2013	14
11	o-Benzenedisulfonimido–sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII Bioorganic & Medicinal Chemistry ·Özlen Güzel-Akdemir,Atilla Akdemir,Semra Işık,Daniela Vullo,Claudiu T. Supuran	2013	22
12	Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms Bioorganic & Medicinal Chemistry ·Shyamasri Biswas,Mayank Aggarwal,Özlen Güzel-Akdemir,Andrea Scozzafava,Robert McKenna,Claudiu T. Supuran	2011	44
13	Carbonic anhydrase inhibitors. The β-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides Bioorganic & Medicinal Chemistry Letters ·Özlen Güzel-Akdemir,Alfonso Maresca,Rebecca A. Hall,Andrea Scozzafava,Antonio Mastrolorenzo,Fritz A. Mühlschlegel,Claudiu T. Supuran	2010	20
14	Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors Bioorganic & Medicinal Chemistry Letters ·Özlen Güzel-Akdemir,Alessio Innocenti,Andrea Scozzafava,Aydın Salman,Claudiu T. Supuran	2009	29
15	Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB Bioorganic & Medicinal Chemistry ·Özlen Güzel-Akdemir,Alessio Innocenti,Andrea Scozzafava,Aydın Salman,Claudiu T. Supuran	2009	36
16	Carbonic anhydrase inhibitors. The nematode α-carbonic anhydrase of Caenorhabditis elegans CAH-4b is highly inhibited by 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides Bioorganic & Medicinal Chemistry ·Özlen Güzel-Akdemir,Alessio Innocenti,Rebecca A. Hall,Andrea Scozzafava,Fritz A. Mühlschlegel,Claudiu T. Supuran	2009	16
17	Synthesis of new spiroindolinones incorporating a benzothiazole moiety as antioxidant agents European Journal of Medicinal Chemistry ·Nilgün Karalı,Özlen Güzel-Akdemir,Nurten Özsoy,Süheyla Özbey,Aydın Salman	2009	122
18	Carbonic anhydrase inhibitors: Synthesis and inhibition studies against mammalian isoforms I–XV with a series of 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides Bioorganic & Medicinal Chemistry ·Özlen Güzel-Akdemir,Alessio Innocenti,Andrea Scozzafava,Aydın Salman,Seppo Parkkila,Mika Hilvo,Claudiu T. Supuran	2008	22
19	Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms: Kinetic and X-ray crystallographic studies Bioorganic & Medicinal Chemistry Letters ·Özlen Güzel-Akdemir,Claudia Temperini,Alessio Innocenti,Andrea Scozzafava,Aydın Salman,Claudiu T. Supuran	2007	47
20	Synthesis, antimycobacterial and antitumor activities of new (1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)methyl N,N-disubstituted dithiocarbamate/O-alkyldithiocarbonate derivatives Bioorganic & Medicinal Chemistry ·Özlen Güzel-Akdemir,Aydın Salman	2006	36

About Özlen Güzel-Akdemir

Özlen Güzel-Akdemir is a scholar working on Organic Chemistry, Pharmacology and Physical and Theoretical Chemistry, having authored 41 papers that have together received 951 indexed citations. Recurring topics across this work include Enzyme function and inhibition (24 papers), Synthesis and Catalytic Reactions (19 papers), Phenothiazines and Benzothiazines Synthesis and Activities (15 papers), Synthesis and biological activity (14 papers), Cholinesterase and Neurodegenerative Diseases (7 papers), Synthesis and Biological Evaluation (6 papers), Cancer therapeutics and mechanisms (5 papers) and Synthesis and Characterization of Heterocyclic Compounds (5 papers). The work is most often cited by research in Organic Chemistry (776 citations), Physical and Theoretical Chemistry (132 citations) and Pharmacology (202 citations). Özlen Güzel-Akdemir has collaborated with scholars based in Türkiye, Italy and United States. Frequent co-authors include Aydın Salman, Claudiu T. Supuran, Nilgün Karalı, Andrea Scozzafava, Atilla Akdemir, Alessio Innocenti, Süheyla Özbey, Nurten Özsoy, Alfonso Maresca and Alexandrù T. Balaban. Their work appears in journals such as International Journal of Molecular Sciences, Journal of Medicinal Chemistry and European Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact