Ja̅nis Leita̅ns

1.2k citations

27 papers · 958 indexed · h-index 15

Molecular Biology top 10%
Organic Chemistry top 5%
Pharmacology top 5%
Physical and Theoretical Chemistry top 5%
Computational Theory and Mathematics top 5%

Co-authors: Kaspars Tārs Andris Kazāks Claudiu T. Supuran Raivis Žalubovskis Jekaterīna Ivanova Daniela Vullo Alons Lends Aiga Grandāne
Topics: Enzyme function and inhibition (22 papers)Synthesis and Catalytic Reactions (20 papers)Chemical Reactions and Mechanisms (7 papers)
Cited by: Organic Chemistry Physical and Theoretical Chemistry Pharmacology
Journals: Chemical Communications International Journal of Molecular Sciences Biophysical Journal
Partner nations: Latvia Italy Lithuania

In The Last Decade

Ja̅nis Leita̅ns

25 papers receiving 953 citations

Peers

Countries citing papers authored by Ja̅nis Leita̅ns

Since Specialization

Citations

This map shows the geographic impact of Ja̅nis Leita̅ns's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ja̅nis Leita̅ns with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ja̅nis Leita̅ns more than expected).

Fields of papers citing papers by Ja̅nis Leita̅ns

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ja̅nis Leita̅ns. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ja̅nis Leita̅ns. The network helps show where Ja̅nis Leita̅ns may publish in the future.

Co-authorship network of co-authors of Ja̅nis Leita̅ns

This figure shows the co-authorship network connecting the top 25 collaborators of Ja̅nis Leita̅ns. A scholar is included among the top collaborators of Ja̅nis Leita̅ns based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ja̅nis Leita̅ns. Ja̅nis Leita̅ns is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Affinity and Selectivity of Protein–Ligand Recognition: A Minor Chemical Modification Changes Carbonic Anhydrase Binding Profile 2025 ·Journal of Medicinal Chemistry ·(unknown),(unknown),(unknown),Edita Čapkauskaitė,(unknown),А. В. Смирнов,(unknown),Ja̅nis Leita̅ns,J. Brynda,Andris Kazāks,Lina Baranauskienė,E. Manakova,S. Gražulis,Visvaldas Kairys,Kaspars Tārs,Pavlína Řezáčová,Daumantas Matulis	0
2	Di-meta-Substituted Fluorinated Benzenesulfonamides as Potent and Selective Anticancer Inhibitors of Carbonic Anhydrase IX and XII 2025 ·Journal of Medicinal Chemistry ·(unknown),(unknown),(unknown),Ja̅nis Leita̅ns,E. Manakova,(unknown),(unknown),Andris Kazāks,(unknown),(unknown),(unknown),(unknown),(unknown),Kaspars Tārs,S. Gražulis,Jurgita Matulienė,Virginija Dudutienė,(unknown),Daumantas Matulis,Asta Zubrienė	1
3	From X-ray crystallographic structure to intrinsic thermodynamics of protein–ligand binding using carbonic anhydrase isozymes as a model system 2024 ·IUCrJ ·(unknown),А. В. Смирнов,E. Manakova,Lina Baranauskienė,Vytautas Petrauskas,Asta Zubrienė,Jurgita Matulienė,Virginija Dudutienė,Edita Čapkauskaitė,(unknown),Ja̅nis Leita̅ns,S. Gražulis,Kaspars Tārs,Daumantas Matulis	1
4	Atropo/Tropo Flexibility: A Tool for Design and Synthesis of Self-Adaptable Inhibitors of Carbonic Anhydrases and Their Antiproliferative Effect 2023 ·Journal of Medicinal Chemistry ·Jekaterīna Ivanova,Alessio Nocentini,Kaspars Tārs,Ja̅nis Leita̅ns,(unknown),Andris Kazāks,(unknown),Claudiu T. Supuran,Raivis Žalubovskis	11
5	Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX 2023 ·ChemMedChem ·Ja̅nis Leita̅ns,Andris Kazāks,(unknown),Claudiu T. Supuran,Ināra Akopjana,Jekaterīna Ivanova,Raivis Žalubovskis,Kaspars Tārs	2
6	Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX 2021 ·International Journal of Molecular Sciences ·(unknown),Edita Čapkauskaitė,(unknown),А. В. Смирнов,Ja̅nis Leita̅ns,Andris Kazāks,(unknown),(unknown),(unknown),Jelena Jachno,(unknown),Vaida Linkuvienė,Andrius Sakalauskas,E. Manakova,S. Gražulis,Jurgita Matulienė,Kaspars Tārs,Daumantas Matulis	12
7	Aryl-4,5-dihydro-1H-pyrazole-1-carboxamide Derivatives Bearing a Sulfonamide Moiety Show Single-digit Nanomolar-to-Subnanomolar Inhibition Constants against the Tumor-associated Human Carbonic Anhydrases IX and XII 2020 ·International Journal of Molecular Sciences ·(unknown),(unknown),Mariangela Ceruso,Ja̅nis Leita̅ns,Andris Kazāks,Kaspars Tārs,Paola Gratteri,Claudiu T. Supuran,Alessio Nocentini,(unknown)	6
8	Isoform-Selective Enzyme Inhibitors by Exploring Pocket Size According to the Lock-and-Key Principle 2020 ·Biophysical Journal ·Virginija Dudutienė,Asta Zubrienė,Visvaldas Kairys,А. В. Смирнов,Joana Smirnovienė,Ja̅nis Leita̅ns,Andris Kazāks,Kaspars Tārs,(unknown),S. Gražulis,Daumantas Matulis	10
9	Extending the Inhibition Profiles of Coumarin-Based Compounds Against Human Carbonic Anhydrases: Synthesis, Biological, and In Silico Evaluation 2019 ·Molecules ·В. Г. Карцев,Athina Geronikaki,Silvia Bua,Alessio Nocentini,Anthi Petrou,Boris V. Lichitsky,M. S. Frasinyuk,Ja̅nis Leita̅ns,Andris Kazāks,Kaspars Tārs,Claudiu T. Supuran	9
10	Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms 2019 ·European Journal of Medicinal Chemistry ·(unknown),Edita Čapkauskaitė,(unknown),Vaida Linkuvienė,(unknown),А. В. Смирнов,Ja̅nis Leita̅ns,Andris Kazāks,(unknown),E. Manakova,S. Gražulis,Kaspars Tārs,Daumantas Matulis	14
11	Synthesis of novel dipeptide sulfonamide conjugates with effective carbonic anhydrase I, II, IX, and XII inhibitory properties 2018 ·Bioorganic Chemistry ·Nesrin Buğday,F. Zehra Küçükbay,Hasan Küçükbay,Silvia Bua,Gianluca Bartolucci,Ja̅nis Leita̅ns,Andris Kazāks,Kaspars Tārs,Claudiu T. Supuran	21
12	New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors 2018 ·Bioorganic Chemistry ·Halise İnci Gül,Cem Yamalı,Hiroshi Sakagami,Andrea Angeli,Ja̅nis Leita̅ns,Andris Kazāks,Kaspars Tārs,Dilan Özmen Özgün,Claudiu T. Supuran	117
13	3H-1,2-Benzoxathiepine 2,2-Dioxides: a New Class of Isoform-Selective Carbonic Anhydrase Inhibitors 2017 ·publication.editionName ·(unknown),(unknown),Raivis Žalubovskis,Daniela Vullo,Andris Kazāks,Ja̅nis Leita̅ns,Kaspars Tārs,Claudiu T. Supuran	1
14	N-Substituted and ring opened saccharin derivatives selectively inhibit transmembrane, tumor-associated carbonic anhydrases IX and XII 2017 ·Bioorganic & Medicinal Chemistry ·Jekaterīna Ivanova,Fabrizio Carta,Daniela Vullo,Ja̅nis Leita̅ns,Andris Kazāks,Kaspars Tārs,Raivis Žalubovskis,Claudiu T. Supuran	38
15	5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations 2016 ·Bioorganic & Medicinal Chemistry ·Jekaterīna Ivanova,(unknown),Raivis Žalubovskis,Ja̅nis Leita̅ns,Andris Kazāks,Daniela Vullo,Kaspars Tārs,Claudiu T. Supuran	23
16	Structures of Plasmepsin II from Plasmodium Falciparum in Complex with Two Hydroxyethylamine-based Inhibitors 2015 ·publication.editionName ·Rosario Recacha,Ja̅nis Leita̅ns,Ināra Akopjana,(unknown),Pēteris Trapencieris,Kristaps Jaudzems	0
17	Structures of plasmepsin II fromPlasmodium falciparumin complex with two hydroxyethylamine-based inhibitors 2015 ·Acta Crystallographica Section F Structural Biology Communications ·Rosario Recacha,Ja̅nis Leita̅ns,Ināra Akopjana,(unknown),Pēteris Trapencieris,Kristaps Jaudzems,Aigars Jirgensons,Kaspars Tārs	16
18	Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV 2015 ·Journal of Medicinal Chemistry ·Dace Rasiņa,Mārtiņš Otikovs,Ja̅nis Leita̅ns,Rosario Recacha,(unknown),I. Kanepe,(unknown),(unknown),Kaspars Tārs,Michael J. Blackman,Kristaps Jaudzems,Aigars Jirgensons	46
19	Targeting Carnitine Biosynthesis: Discovery of New Inhibitors against γ-Butyrobetaine Hydroxylase 2014 ·Journal of Medicinal Chemistry ·Kaspars Tārs,Ja̅nis Leita̅ns,Andris Kazāks,(unknown),Edgars Liepinsh,Janis Kuka,Marina Makrecka‐Kuka,(unknown),(unknown),(unknown),Solveiga Grı̄nberga,Edvards Liepinsh,Ivars Kalvinsh,Maija Dambrova,Einārs Loža,Osvalds Pugovičs	37
20	5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: Solution and X-ray crystallographic studies 2013 ·Bioorganic & Medicinal Chemistry ·Ja̅nis Leita̅ns,(unknown),Muhammet Tanç,(unknown),Raivis Žalubovskis,Kaspars Tārs,Claudiu T. Supuran	32

About Ja̅nis Leita̅ns

Ja̅nis Leita̅ns is a scholar working on Physical and Theoretical Chemistry, Organic Chemistry and Molecular Biology, having authored 27 papers that have together received 958 indexed citations. Recurring topics across this work include Enzyme function and inhibition (22 papers), Synthesis and Catalytic Reactions (20 papers) and Chemical Reactions and Mechanisms (7 papers). The work is most often cited by research in Organic Chemistry (684 citations), Physical and Theoretical Chemistry (158 citations) and Pharmacology (245 citations). Ja̅nis Leita̅ns has collaborated with scholars based in Latvia, Italy and Lithuania. Frequent co-authors include Kaspars Tārs, Andris Kazāks, Claudiu T. Supuran, Raivis Žalubovskis, Jekaterīna Ivanova, Daniela Vullo, Alons Lends, Aiga Grandāne, Andrea Scozzafava and Muhammet Tanç. Their work appears in journals such as Chemical Communications, International Journal of Molecular Sciences and Biophysical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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