Nils Blüthgen

14.6k citations

114 papers · 7.9k indexed · 3 hit papers · h-index 36

Impact in

Molecular Biology top 1%
- Genomics and Chromatin Dynamics
- RNA Research and Splicing
- Gene Regulatory Network Analysis
- RNA and protein synthesis mechanisms
Ecology, Evolution, Behavior and Systematics top 0.5%
- Plant and animal studies

Papers in

Biophysics 9
Modeling and Simulation 7

Co-authors: Nico Blüthgen Florian Menzel Stefan Legewie Hanspeter Herzel Johannes Meisig Edda G. Schulz Luca Giorgetti Édith Heard
Journals: Molecular Systems Biology (9 papers)Nucleic Acids Research (8 papers)Bioinformatics (8 papers)Nature Communications (6 papers)PLoS Computational Biology (5 papers)
Partner nations: Germany United States United Kingdom

In The Last Decade

Nils Blüthgen

111 papers receiving 7.8k citations

Hit Papers

align trajectories log scale

Perturbation-response genes reveal signaling footprints in cancer gene expression 2017 · 444 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2017 Nature Communications
2012 Nature
2006 BMC Ecology

Peers

Countries citing papers authored by Nils Blüthgen

Since Specialization

Citations

This map shows the geographic impact of Nils Blüthgen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nils Blüthgen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nils Blüthgen more than expected).

Fields of papers citing papers by Nils Blüthgen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nils Blüthgen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nils Blüthgen. The network helps show where Nils Blüthgen may publish in the future.

Co-authors

The 25 scholars most cited alongside Nils Blüthgen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Nils Blüthgen Line = papers co-authored together Nils Blüthgen links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Spike-in enhanced phosphoproteomics uncovers synergistic signaling responses to MEK inhibition in colon cancer cells Nature Communications ·Y. Xu, Bertram Klinger, Anja Sieber, Tiziano Camporesi, Henrik Zauber, Alessio Traficante, Mohamed Haji, М. А. Григорьева, Philipp Mertins, Nils Blüthgen, Matthias Selbach	2025	1
2	High‐confidence calling of normal epithelial cells allows identification of a novel stem‐like cell state in the colorectal cancer microenvironment International Journal of Cancer ·Fernando P. Ferraz, Eric Blanc, Stefan Peidli, Philip Bischoff, Alexandra Trinks, David Horst, Christine Sers, Nils Blüthgen, Dieter Beule, Markus Morkel, Benedikt Obermayer	2024	1
3	scPerturb: harmonized single-cell perturbation data Nature Methods ·Stefan Peidli, sonoko Asino, Ciyue Shen, Torsten Groß, Joseph Min, WU Shangbai, Bo Yuan, Linus J. Schumacher, Jake P. Taylor‐King, Debora S. Marks, Augustin Luna, Nils Blüthgen, Chris Sander	2024	46
4	Modeling unveils sex differences of signaling networks in mouse embryonic stem cells Molecular Systems Biology ·L. P. Carik, Kurygin Aa, Bertram Klinger, Anja Sieber, Ilona Dunkel, Nils Blüthgen, Edda G. Schulz	2023	1
5	In Silico Analysis Predicts Nuclear Factors NR2F6 and YAP1 as Mesenchymal Subtype-Specific Therapeutic Targets for Ovarian Cancer Patients Cancers ·Ingrid Cáceres Würsig, Pedro R. Cutillas, Mirjana Kessler, Jalid Sehouli, Elena Ioana Braicu, Nils Blüthgen, Hagen Kulbe	2023	2
6	The single‐cell transcriptional landscape of lung carcinoid tumors International Journal of Cancer ·Philip Bischoff, Alexandra Trinks, Alma L Moldenee, Benedikt Obermayer, J. Patrick Pett, Philipp Jurmeister, J. B. Abele, Tomasz Dziodzio, Jens‐Carsten Rückert, Jens Neudecker, Christine S. Falk, Dieter Beule, Christine Sers, Markus Morkel, David Horst, Frederick Klauschen, Nils Blüthgen	2022	18
7	Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test Chemical Research in Toxicology ·Effendi Effendi, Jane L. Sumner, Franziska Kappenberg, J. X. Jessie-Bay, Jonathan Blum, Tanja Waldmann, Nils Blüthgen, Johannes Meisig, Katrin Madjar, Margit Henry, Andreea Giurgiuveanu, Rosemarie Marchan, Karolina Edlund, Marcel Leist, Jörg Rahnenführer, Agapios Sachinidis, Jan G. Hengstler	2022	4
8	High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation Cells ·Jane L. Sumner, Effendi Effendi, Franziska Kappenberg, Andrea Bergstrand, J. X. Jessie-Bay, Jonathan Blum, Tanja Waldmann, Nils Blüthgen, Johannes Meisig, Katrin Madjar, Margit Henry, Andreea Giurgiuveanu, Li Chao, Rosemarie Marchan, Karolina Edlund, Marcel Leist, Jörg Rahnenführer, Agapios Sachinidis, Jan G. Hengstler	2022	2
9	Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance PLoS Computational Biology ·Kurygin Aa, Bertram Klinger, Tommaso Mari, Joern Toedling, Eric Blanc, Gan Liang-ji, Michal Nadler-Holly, Matthias Ziehm, Anja Sieber, Falk Hertwig, Dieter Beule, Angelika Eggert, Johannes H. Schulte, Matthias Selbach, Nils Blüthgen	2021	5
10	Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma Cell Death and Disease ·Ulrike Schoetz, Diana Klein, Julia Heß, K P - Costin, Steffen Spoerl, Michael Orth, 辰夫柴田, Roman Hennel, Anja Sieber, Ute Ganswindt, Benedikt Luka, Andreas Thomsen, Kristian Unger, Verena Jendrossek, Horst Zitzelsberger, Nils Blüthgen, Claus Belka, Steffen Unkel, Bertram Klinger, Kirsten Lauber	2021	46
11	Classification of Molecular Subtypes of High-Grade Serous Ovarian Cancer by MALDI-Imaging Cancers ·Ingrid Cáceres Würsig, Oliver Klein, Silvia Darb‐Esfahani, Hedwig Lammert, 山田智紀, Eliane T. Taube, Wolfgang Schmitt, Luca Fiorilla, David Horst, Felix Dreher, Joshy George, David D.L. Bowtell, Oliver Dorigo, Michael Hummel, Jalid Sehouli, Nils Blüthgen, Hagen Kulbe, Elena Ioana Braicu	2021	14
12	Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma Oncogene ·Philip Bischoff, Alexandra Trinks, Benedikt Obermayer, J. Patrick Pett, Alma L Moldenee, Florian Uhlitz, Xizi Liang, Annika Lehmann, Philipp Jurmeister, J. B. Abele, Tomasz Dziodzio, Jens‐Carsten Rückert, Jens Neudecker, Christine S. Falk, Dieter Beule, Christine Sers, Markus Morkel, David Horst, Nils Blüthgen, Frederick Klauschen	2021	131
13	Identifiability and experimental design in perturbation studies Bioinformatics ·Torsten Groß, Nils Blüthgen	2020	9
14	Robust network inference using response logic Bioinformatics ·Torsten Groß, Matthew Wongchenko, Yibing Yan, Nils Blüthgen	2019	5
15	Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium Nature Communications ·Marie-Céline Lacombe, Thomas Sell, Mareen Lüthen, Florian Uhlitz, Bertram Klinger, Pamela Riemer, Claudia Giesecke‐Thiel, M Lapèze, John O. Eichung, Désirée Kunkel, Beatrix Fauler, Thorsten Mielke, Nevenka Černigoj-Sadar, Bernhard G. Herrmann, Christine Sers, Nils Blüthgen, Markus Morkel	2019	64
16	Comparative Network Reconstruction using mixed integer programming Bioinformatics ·Evert Bosdriesz, Anirudh Prahallad, Bertram Klinger, Anja Sieber, Astrid Bosma, René Bernards, Nils Blüthgen, Lodewyk F.A. Wessels	2018	6
17	Modelling signalling networks from perturbation data Bioinformatics ·Kurygin Aa, Bertram Klinger, Torsten Groß, Anja Sieber, Anirudh Prahallad, Evert Bosdriesz, Lodewyk F.A. Wessels, Nils Blüthgen	2018	14
18	Drug Resistance Mechanisms in Colorectal Cancer Dissected with Cell Type–Specific Dynamic Logic Models Cancer Research ·Federica Eduati, Christian Krog Madsen, Bertram Klinger, Thomas Cokelaer, Anja Sieber, I.S. Myalkovskiy, Kurygin Aa, Mathew J. Garnett, Nils Blüthgen, Julio Sáez-Rodríguez	2017	73
19	MicroRNA control of protein expression noise Science ·Jörn M. Schmiedel, Sandy Klemm, Yannan Zheng, А.М. Бурдин, Nils Blüthgen, Debora S. Marks, Alexander van Oudenaarden	2015	281
20	Transcriptional feedbacks in mammalian signal transduction pathways facilitate rapid and reliable protein induction Molecular BioSystems ·Nils Blüthgen	2010	10

About Nils Blüthgen

Nils Blüthgen is a scholar working on Biophysics, Modeling and Simulation, Molecular Biology, Cancer Research and Cell Biology, having authored 114 papers that have together received 7.9k indexed citations. Recurring topics across this work include Gene Regulatory Network Analysis (32 papers), Bioinformatics and Genomic Networks (17 papers), RNA Research and Splicing (13 papers), Melanoma and MAPK Pathways (12 papers), Genomics and Chromatin Dynamics (12 papers), Single-cell and spatial transcriptomics (12 papers), Gene expression and cancer classification (9 papers) and Pluripotent Stem Cells Research (9 papers). The work is most often cited by research in Molecular Biology (5.2k citations), Ecology, Evolution, Behavior and Systematics (1.4k citations), Nature and Landscape Conservation (727 citations), Cancer Research (752 citations) and Plant Science (1.8k citations). Nils Blüthgen has collaborated with scholars based in Germany, United States and United Kingdom. Frequent co-authors include Nico Blüthgen, Florian Menzel, Stefan Legewie, Hanspeter Herzel, Johannes Meisig, Edda G. Schulz, Luca Giorgetti, Édith Heard, Ikuhiro Okamoto and Emmanuel Barillot. Their work appears in journals such as Molecular Systems Biology, Nucleic Acids Research, Bioinformatics, Nature Communications and PLoS Computational Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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