Nicolas Legrand

4.4k citations

47 papers · 3.2k indexed · 1 hit paper · h-index 25

Impact in

Immunology top 1%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- IL-33, ST2, and ILC Pathways
- Immunotherapy and Immune Responses
Virology top 2%
- HIV Research and Treatment

Papers in

Immunology 31
- Immune Cell Function and Interaction 22
- T-cell and B-cell Immunology 22
- Immunotherapy and Immune Responses 16
Virology 6
- HIV Research and Treatment 6

Co-authors: Hergen Spits Kees Weijer António A. Freitas Martine Papiernik Afonso R. M. Almeida James P. Di Santo Nicholas D. Huntington Nuno L. Alves
Journals: The Journal of Immunology (8 papers)European Journal of Immunology (4 papers)The Journal of Experimental Medicine (3 papers)Blood (3 papers)Journal of Leukocyte Biology (2 papers)
Partner nations: Netherlands France United States

In The Last Decade

Nicolas Legrand

45 papers receiving 3.1k citations

Hit Papers

align trajectories log scale

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues 2013 · 775 citations

Peers

Countries citing papers authored by Nicolas Legrand

Since Specialization

Citations

This map shows the geographic impact of Nicolas Legrand's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nicolas Legrand with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nicolas Legrand more than expected).

Fields of papers citing papers by Nicolas Legrand

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nicolas Legrand. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nicolas Legrand. The network helps show where Nicolas Legrand may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Nicolas Legrand, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Nicolas Legrand Line = papers co-authored together Nicolas Legrand links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Intranasal delivery of a chimpanzee adenovirus vector expressing a pre-fusion spike (BV-AdCoV-1) protects golden Syrian hamsters against SARS-CoV-2 infection Frontiers in Cellular and Infection Microbiology ·Shen Wang, Long Xu, Ting Mu, Francisney Pinto, Ping Zhao, Liang Xie, Desirée Carolina, Yue Wu, Nicolas Legrand, Mike Hayashi, Guillaume Fichet, Yi Liu, 유영배, Jin Zhao, Min Ji, Bo Gong, Michel Klein, К.Б. Устинович	2022	5
2	10 ^th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals mAbs ·Sophie Tourdot, YU Da-chuan, Juliana Bessa, Philippe Broët, Anna Fogdell‐Hahn, Mario Giorgi, Vibha Jawa, Klaudia Kuranda, Nicolas Legrand, 李美淑, João Pedras-Vasconcelos, Kizito K. Mwajombe, Paula Salmikangas, David W. Scott, Veerle Snoeck, S. Soto Soto, Sebastian Spindeldreher, Daniel Kramer	2020	9
3	Homogeneous single-label tyrosine kinase activity assay for high throughput screening Analytica Chimica Acta ·P. Senthil Priya, Kari Kopra, Ahmad Rendy, Nicolas Legrand, Harri Härmä	2015	5
4	Human fetal liver cells for regulated ex vivo erythropoietin gene therapy Molecular Therapy — Methods & Clinical Development ·V. A. S., Suzanne Duijst, Johan K. Hiralall, Nicolas Legrand, Thomas van Gulik, Ruurdtje Hoekstra, Jurgen Seppen	2014	4
5	Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues Nature Immunology ·Jochem H. Bernink, Charlotte P. Peters, JosÃ© AgustÃn GarcÃa, Anje A. te Velde, Sybren L. Meijer, Kees Weijer, Hulda S. Hreggvidsdottir, Sigrid E.M. Heinsbroek, Nicolas Legrand, Christianne J. Buskens, Willem A. Bemelman, Jenny Mjösberg, Hergen Spits Hit paper breakdown →	2013	775
6	A Sensitive Cell-Based Assay to Measure the Doxycycline Concentration in Biological Samples Human Gene Therapy ·Wendy Kleibeuker, Xue Zhou, Mireille Centlivre, Nicolas Legrand, Mark Page, Neil Almond, Ben Berkhout, Atze T. Das	2009	18
7	IL-7 Enhances Thymic Human T Cell Development in “Human Immune System” Rag2−/−IL-2Rγc−/− Mice without Affecting Peripheral T Cell Homeostasis The Journal of Immunology ·Anja U. van Lent, Wendy Dontje, Maho Nagasawa, V. V. Mishova, Arjen Q. Bakker, Stephan M. Pouw, A. Rojas, Kees Weijer, Jan J. Cornelissen, Bianca Blom, James P. Di Santo, Hergen Spits, Nicolas Legrand	2009	64
8	Repopulation Efficiencies of Adult Hepatocytes, Fetal Liver Progenitor Cells, and Embryonic Stem Cell-Derived Hepatic Cells in Albumin-Promoter-Enhancer Urokinase-Type Plasminogen Activator Mice American Journal Of Pathology ·Н. В. Гусакова, Qinggong Yuan, Pablo D. Becker, Tobias Cantz, Marcus Iken, Michael Rothe, Sant Rayn Pasricha, Michael Bock, J. Ahui Brou, Nicolas Legrand, Heiner Wedemeyer, Kees Weijer, Hergen Spits, Michael P. Manns, Jun Cai, Hongkui Deng, James P. Di Santo, Carlos A. Guzmán, Michael Ott	2009	83
9	T cell–independent development and induction of somatic hypermutation in human IgM+IgD+CD27+ B cells The Journal of Experimental Medicine ·Ferenc A. Scheeren, Maho Nagasawa, Kees Weijer, Tom Cupedo, Jörg Kirberg, Nicolas Legrand, Hergen Spits	2008	85
10	Experimental Model for the Study of the Human Immune System Innate Immunity ·Nicolas Legrand, Kees Weijer, Hergen Spits	2008	26
11	Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2-/-γc-/-) mouse model Gene Therapy ·Olivier ter Brake, Nicolas Legrand, Karin J. von Eije, Mireille Centlivre, Hergen Spits, Kees Weijer, Bianca Blom, Ben Berkhout	2008	64
12	Functional Human Antigen-Specific T Cells Produced In Vitro Using Retroviral T Cell Receptor Transfer into Hematopoietic Progenitors The Journal of Immunology ·Anja U. van Lent, Maho Nagasawa, Marleen M. van Loenen, Remko Schotte, Ton N. Schumacher, Mirjam H.M. Heemskerk, Hergen Spits, Nicolas Legrand	2007	38
13	Human thymus regeneration and T cell reconstitution Seminars in Immunology ·Nicolas Legrand, Wendy Dontje, Anja U. van Lent, Hergen Spits, Bianca Blom	2007	30
14	The clone size of peripheral CD8 T cells is regulated by TCR promiscuity The Journal of Experimental Medicine ·Yi Hao, Nicolas Legrand, António A. Freitas	2006	37
15	Experimental Models to Study Development and Function of the Human Immune System In Vivo The Journal of Immunology ·Nicolas Legrand, Kees Weijer, Hergen Spits	2006	135
16	In Vivo Modulation of Gene Expression by Lentiviral Transduction in “Human Immune System” Rag2−/−γc −/− Mice Methods in molecular biology ·Anja U. van Lent, Mireille Centlivre, Maho Nagasawa, Julien J. Karrich, Stephan M. Pouw, Kees Weijer, Hergen Spits, Bianca Blom, Nicolas Legrand	2006	9
17	In Vivo and in Absence of a Thymus, the Enforced Expression of the Notch Ligands Delta-1 or Delta-4 Promotes T Cell Development with Specific Unique Effects The Journal of Immunology ·José Plácido, Emmanuelle Six, Nicolas Fazilleau, Laurent Mascarell, Nicolas Legrand, Marie-Pierre Mailhé, Ana Cumano, Yacine Laâbi, António A. Freitas	2005	35
18	Homeostasis of Peripheral CD4+ T Cells: IL-2Rα and IL-2 Shape a Population of Regulatory Cells That Controls CD4+ T Cell Numbers The Journal of Immunology ·Afonso R. M. Almeida, Nicolas Legrand, Martine Papiernik, António A. Freitas	2002	390
19	CD8+ T Lymphocytes in Double αβ TCR Transgenic Mice. I. TCR Expression and Thymus Selection in the Absence or in the Presence of Self-Antigen The Journal of Immunology ·Nicolas Legrand, António A. Freitas	2001	8
20	CD8+ T Lymphocytes in Double αβ TCR Transgenic Mice. II. Competitive Fitness of Dual αβ TCR CD8+ T Lymphocytes in the Peripheral Pools The Journal of Immunology ·Nicolas Legrand, António A. Freitas	2001	8

About Nicolas Legrand

Nicolas Legrand is a scholar working on Immunology, Virology, Oncology, Genetics and Immunology and Allergy, having authored 47 papers that have together received 3.2k indexed citations. Recurring topics across this work include Immune Cell Function and Interaction (22 papers), T-cell and B-cell Immunology (22 papers), Immunotherapy and Immune Responses (16 papers), CAR-T cell therapy research (10 papers), Virus-based gene therapy research (9 papers), HIV Research and Treatment (6 papers), RNA Interference and Gene Delivery (5 papers) and SARS-CoV-2 and COVID-19 Research (2 papers). The work is most often cited by research in Immunology (2.4k citations), Virology (230 citations), Hematology (247 citations), Oncology (516 citations) and Genetics (442 citations). Nicolas Legrand has collaborated with scholars based in Netherlands, France and United States. Frequent co-authors include Hergen Spits, Kees Weijer, António A. Freitas, Martine Papiernik, Afonso R. M. Almeida, James P. Di Santo, Nicholas D. Huntington, Nuno L. Alves, Willem A. Bemelman and Charlotte P. Peters. Their work appears in journals such as The Journal of Immunology, European Journal of Immunology, The Journal of Experimental Medicine, Blood and Journal of Leukocyte Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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