Michael R. Barbachyn

4.8k total citations · 1 hit paper
38 papers, 3.7k citations indexed

About

Michael R. Barbachyn is a scholar working on Organic Chemistry, Molecular Biology and Infectious Diseases. According to data from OpenAlex, Michael R. Barbachyn has authored 38 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Organic Chemistry, 19 papers in Molecular Biology and 10 papers in Infectious Diseases. Recurrent topics in Michael R. Barbachyn's work include Phenothiazines and Benzothiazines Synthesis and Activities (9 papers), Synthesis and Catalytic Reactions (8 papers) and Microbial Natural Products and Biosynthesis (7 papers). Michael R. Barbachyn is often cited by papers focused on Phenothiazines and Benzothiazines Synthesis and Activities (9 papers), Synthesis and Catalytic Reactions (8 papers) and Microbial Natural Products and Biosynthesis (7 papers). Michael R. Barbachyn collaborates with scholars based in United States, Netherlands and France. Michael R. Barbachyn's co-authors include Charles W. Ford, Douglas K. Hutchinson, Gary E. Zurenko, Steven J. Brickner, Kevin C. Grega, Karen Joy Shaw, Betty H. Yagi, Ronda D. Schaadt, Peter R. Manninen and Stuart A. Garmon and has published in prestigious journals such as Journal of the American Chemical Society, Angewandte Chemie International Edition and Nature Communications.

In The Last Decade

Michael R. Barbachyn

37 papers receiving 3.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Substituent Effects on the Antibacterial Activity of Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Expanded Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalis

2000 662 citations Michaël Génin, Michael R. Barbachyn et al. Journal of Medicinal Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Michael R. Barbachyn United States	23	2.1k	1.4k	1.1k	499	409	38	3.7k
Gary E. Zurenko United States	26	1.6k 0.7×	1.2k 0.9×	1.2k 1.1×	602 1.2×	520 1.3×	65	3.4k
Douglas K. Hutchinson United States	17	1.4k 0.7×	924 0.7×	886 0.8×	324 0.6×	276 0.7×	21	2.5k
Steven J. Brickner United States	19	966 0.5×	822 0.6×	1.1k 0.9×	366 0.7×	318 0.8×	32	2.3k
John M. Domagala United States	27	1.0k 0.5×	1.4k 1.0×	657 0.6×	1.1k 2.3×	941 2.3×	62	3.2k
Kevin C. Grega United States	11	1.2k 0.5×	618 0.5×	347 0.3×	161 0.3×	85 0.2×	13	1.6k
Fabio Prati Italy	31	990 0.5×	1.1k 0.8×	253 0.2×	533 1.1×	1.1k 2.6×	115	2.6k
Michael H. Cynamon United States	41	946 0.4×	1.5k 1.1×	2.9k 2.6×	434 0.9×	573 1.4×	132	4.8k
Robert J. Kerns United States	29	1.2k 0.6×	2.6k 1.9×	565 0.5×	997 2.0×	1.3k 3.1×	75	4.1k
Fredrik Almqvist Sweden	35	1.6k 0.7×	1.8k 1.3×	179 0.2×	136 0.3×	343 0.8×	127	4.1k
Jacob J. Plattner United States	34	2.3k 1.1×	2.1k 1.5×	989 0.9×	295 0.6×	126 0.3×	113	4.8k

Countries citing papers authored by Michael R. Barbachyn

Since Specialization

Citations

This map shows the geographic impact of Michael R. Barbachyn's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael R. Barbachyn with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael R. Barbachyn more than expected).

Fields of papers citing papers by Michael R. Barbachyn

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael R. Barbachyn. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael R. Barbachyn. The network helps show where Michael R. Barbachyn may publish in the future.

Co-authorship network of co-authors of Michael R. Barbachyn

This figure shows the co-authorship network connecting the top 25 collaborators of Michael R. Barbachyn. A scholar is included among the top collaborators of Michael R. Barbachyn based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael R. Barbachyn. Michael R. Barbachyn is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Friggen, Annemieke H., Michael H. Silverman, Michael R. Barbachyn, et al.. (2025). A unique inhibitor conformation selectively targets the DNA polymerase PolC of Gram-positive priority pathogens. Nature Communications. 16(1). 9784–9784.

Su, Chih‐Chia, Christian T. Meyer, Meredith D. Betterton, et al.. (2023). Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio. 14(6). e0249223–e0249223. 4 indexed citations

Zhang, Shi‐Yuan, Ronald L. Blankespoor, Shannon M. Biros, et al.. (2020). The Synthesis of Functionalized 3-Aryl- and 3-Heteroaryloxazolidin-2-ones and Tetrahydro-3-aryl-1,3-oxazin-2-ones via the Iodocyclocarbamation Reaction: Access to Privileged Chemical Structures and Scope and Limitations of the Method. The Journal of Organic Chemistry. 85(10). 6323–6337. 5 indexed citations

Shaw, Karen Joy & Michael R. Barbachyn. (2011). The oxazolidinones: past, present, and future. Annals of the New York Academy of Sciences. 1241(1). 48–70. 206 indexed citations

Starr, Jeremy T., Richard J. Sciotti, Debra Hanna, et al.. (2009). 5-(2-Pyrimidinyl)-imidazo[1,2-a]pyridines are antibacterial agents targeting the ATPase domains of DNA gyrase and topoisomerase IV. Bioorganic & Medicinal Chemistry Letters. 19(18). 5302–5306. 58 indexed citations

Brickner, Steven J., Michael R. Barbachyn, Douglas K. Hutchinson, & Peter R. Manninen. (2008). Linezolid (ZYVOX), the First Member of a Completely New Class of Antibacterial Agents for Treatment of Serious Gram-Positive Infections. Journal of Medicinal Chemistry. 51(7). 1981–1990. 161 indexed citations

Barbachyn, Michael R. & Charles W. Ford. (2003). Oxazolidinone Structure–Activity Relationships Leading to Linezolid. Angewandte Chemie International Edition. 42(18). 2010–2023. 457 indexed citations

Ciske, Fred L., Michael R. Barbachyn, Michaël Génin, et al.. (2003). The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones. Bioorganic & Medicinal Chemistry Letters. 13(23). 4235–4239. 22 indexed citations

GORDEEV, M. F., C J Hackbarth, Michael R. Barbachyn, et al.. (2003). Novel oxazolidinone–quinolone hybrid antimicrobials. Bioorganic & Medicinal Chemistry Letters. 13(23). 4213–4216. 54 indexed citations

10.

Pearlman, Bruce A., Paul M. Herrinton, Robert C. Gadwood, et al.. (2003). The Synthesis of N-Aryl-5(S)-aminomethyl-2-oxazolidinone Antibacterials and Derivatives in One Step from Aryl Carbamates. Organic Process Research & Development. 7(4). 533–546. 69 indexed citations

11.

Ford, Charles E., Gary E. Zurenko, & Michael R. Barbachyn. (2001). The Discovery of Linezolid, the First Oxazolidinone Antibacterial Agent. PubMed. 1(2). 181–199. 116 indexed citations

12.

Lee, Chi‐Sing, Michael R. Barbachyn, Kevin C. Grega, et al.. (2001). Carbon–carbon-linked (pyrazolylphenyl)oxazolidinones with antibacterial activity against multiple drug resistant gram-positive and fastidious gram-negative bacteria. Bioorganic & Medicinal Chemistry. 9(12). 3243–3253. 25 indexed citations

13.

Barbachyn, Michael R., Steven J. Brickner, Robert C. Gadwood, et al.. (1998). Design, Synthesis, and Evaluation of Novel Oxazolidinone Antibacterial Agents Active Against Multidrug-Resistant Bacteria. Advances in experimental medicine and biology. 456. 219–238. 15 indexed citations

14.

Ford, Charles W., Judith C. Hamel, Douglas Stapert, et al.. (1997). Oxazolidinones: New antibacterial agents. Trends in Microbiology. 5(5). 196–200. 56 indexed citations

15.

Barbachyn, Michael R., Douglas K. Hutchinson, Steven J. Brickner, et al.. (1996). Identification of a Novel Oxazolidinone (U-100480) with Potent Antimycobacterial Activity. Journal of Medicinal Chemistry. 39(3). 680–685. 193 indexed citations

16.

Brickner, Steven J., Douglas K. Hutchinson, Michael R. Barbachyn, et al.. (1996). Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections. Journal of Medicinal Chemistry. 39(3). 673–679. 489 indexed citations

17.

Grega, Kevin C., Michael R. Barbachyn, Steven J. Brickner, & S. A. MIZSAK. (1995). Regioselective Metalation of Fluoroanilines. An Application to the Synthesis of Fluorinated Oxazolidinone Antibacterial Agents. The Journal of Organic Chemistry. 60(16). 5255–5261. 37 indexed citations

18.

Danishefsky, Samuel J., Clarence J. Maring, Michael R. Barbachyn, & Brigitte E. Segmüller. (1984). An approach to the synthesis of carbon-carbon linked disaccharides. The Journal of Organic Chemistry. 49(23). 4564–4565. 23 indexed citations

19.

Johnson, Carl R. & Michael R. Barbachyn. (1982). .beta.-Hydroxysulfoximine-directed Simmons-Smith cyclopropanations. Synthesis of (-)- and (+)-thujopsene. Journal of the American Chemical Society. 104(15). 4290–4291. 18 indexed citations

20.

DeKock, Roger L. & Michael R. Barbachyn. (1979). Proton affinity, ionization energy, and the nature of frontier orbital electron density. Journal of the American Chemical Society. 101(22). 6516–6519. 21 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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