Michael R. Barbachyn

4.8k citations

38 papers · 3.7k indexed · 1 hit paper · h-index 23

Co-authors: Charles W. Ford Douglas K. Hutchinson Gary E. Zurenko Steven J. Brickner Kevin C. Grega Karen Joy Shaw Betty H. Yagi Ronda D. Schaadt
Topics: Phenothiazines and Benzothiazines Synthesis and Activities (9 papers)Synthesis and Catalytic Reactions (8 papers)Microbial Natural Products and Biosynthesis (7 papers)
Cited by: Molecular Medicine Process Chemistry and Technology Organic Chemistry
Journals: Journal of the American Chemical Society Angewandte Chemie International Edition Nature Communications
Partner nations: United States Netherlands France

In The Last Decade

Michael R. Barbachyn

37 papers receiving 3.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Substituent Effects on the Antibacterial Activity of Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Expanded Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalis

2000 662 citations Michaël Génin, Michael R. Barbachyn et al. Journal of Medicinal Chemistry profile →

Peers

Countries citing papers authored by Michael R. Barbachyn

Since Specialization

Citations

This map shows the geographic impact of Michael R. Barbachyn's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael R. Barbachyn with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael R. Barbachyn more than expected).

Fields of papers citing papers by Michael R. Barbachyn

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael R. Barbachyn. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael R. Barbachyn. The network helps show where Michael R. Barbachyn may publish in the future.

Co-authorship network of co-authors of Michael R. Barbachyn

This figure shows the co-authorship network connecting the top 25 collaborators of Michael R. Barbachyn. A scholar is included among the top collaborators of Michael R. Barbachyn based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael R. Barbachyn. Michael R. Barbachyn is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A unique inhibitor conformation selectively targets the DNA polymerase PolC of Gram-positive priority pathogens 2025 ·Nature Communications ·(unknown),Annemieke H. Friggen,(unknown),Michael H. Silverman,(unknown),Michael R. Barbachyn,(unknown),Xiang Yu,(unknown),Meindert H. Lamers,Wiep Klaas Smits	0
2	Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment 2023 ·mBio ·(unknown),Chih‐Chia Su,(unknown),Christian T. Meyer,(unknown),Meredith D. Betterton,Michael R. Barbachyn,Edward Yu,Corrella S. Detweiler	4
3	The Synthesis of Functionalized 3-Aryl- and 3-Heteroaryloxazolidin-2-ones and Tetrahydro-3-aryl-1,3-oxazin-2-ones via the Iodocyclocarbamation Reaction: Access to Privileged Chemical Structures and Scope and Limitations of the Method 2020 ·The Journal of Organic Chemistry ·(unknown),(unknown),(unknown),(unknown),Shi‐Yuan Zhang,Ronald L. Blankespoor,Shannon M. Biros,Richard J. Staples,Steven J. Brickner,Michael R. Barbachyn	5
4	The oxazolidinones: past, present, and future 2011 ·Annals of the New York Academy of Sciences ·Karen Joy Shaw,Michael R. Barbachyn	206
5	5-(2-Pyrimidinyl)-imidazo[1,2-a]pyridines are antibacterial agents targeting the ATPase domains of DNA gyrase and topoisomerase IV 2009 ·Bioorganic & Medicinal Chemistry Letters ·Jeremy T. Starr,Richard J. Sciotti,Debra Hanna,Michael D. Huband,Lisa Mullins,Hongliang Cai,(unknown),(unknown),(unknown),Robert M. Owen,Manjinder S. Lall,(unknown),Huifen Chen,Sandra P. McCurdy,Michael R. Barbachyn	58
6	Linezolid (ZYVOX), the First Member of a Completely New Class of Antibacterial Agents for Treatment of Serious Gram-Positive Infections 2008 ·Journal of Medicinal Chemistry ·Steven J. Brickner,Michael R. Barbachyn,Douglas K. Hutchinson,Peter R. Manninen	161
7	Oxazolidinone Structure–Activity Relationships Leading to Linezolid 2003 ·Angewandte Chemie International Edition ·Michael R. Barbachyn,Charles W. Ford	457
8	The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones 2003 ·Bioorganic & Medicinal Chemistry Letters ·Fred L. Ciske,Michael R. Barbachyn,Michaël Génin,Kevin C. Grega,Chi‐Sing Lee,Lester A. Dolak,Eric P. Seest,William Watt,Wade J. Adams,(unknown),Charles W. Ford,Gary E. Zurenko	22
9	Novel oxazolidinone–quinolone hybrid antimicrobials 2003 ·Bioorganic & Medicinal Chemistry Letters ·M. F. GORDEEV,C J Hackbarth,Michael R. Barbachyn,Lee S. Banitt,James R. Gage,(unknown),Marcela Gómez,Joaquim Trias,(unknown),Gary E. Zurenko,(unknown),Jonathan M. Evans,Richard White,Dinesh V. Patel	54
10	The Synthesis of N-Aryl-5(S)-aminomethyl-2-oxazolidinone Antibacterials and Derivatives in One Step from Aryl Carbamates 2003 ·Organic Process Research & Development ·(unknown),Bruce A. Pearlman,(unknown),(unknown),(unknown),(unknown),(unknown),Paul M. Herrinton,Robert C. Gadwood,(unknown),Mark A. Lyster,Mark T. Maloney,(unknown),Meredith Greene,Michael R. Barbachyn	69
11	The Discovery of Linezolid, the First Oxazolidinone Antibacterial Agent 2001 ·PubMed ·Charles E. Ford,Gary E. Zurenko,Michael R. Barbachyn	116
12	Carbon–carbon-linked (pyrazolylphenyl)oxazolidinones with antibacterial activity against multiple drug resistant gram-positive and fastidious gram-negative bacteria 2001 ·Bioorganic & Medicinal Chemistry ·Chi‐Sing Lee,(unknown),Michael R. Barbachyn,Kevin C. Grega,Lester A. Dolak,Charles W. Ford,Randy Jensen,Eric P. Seest,Judith C. Hamel,Ronda D. Schaadt,Douglas Stapert,Betty H. Yagi,Gary E. Zurenko,Michaël Génin	25
13	Design, Synthesis, and Evaluation of Novel Oxazolidinone Antibacterial Agents Active Against Multidrug-Resistant Bacteria 1998 ·Advances in experimental medicine and biology ·Michael R. Barbachyn,Steven J. Brickner,Robert C. Gadwood,Stuart A. Garmon,Kevin C. Grega,Douglas K. Hutchinson,(unknown),(unknown),Masayuki Taniguchi,Lisa M. Thomasco,Dana S. Toops,Hiroyuki Yamada,Charles W. Ford,Gary E. Zurenko	15
14	Oxazolidinones: New antibacterial agents 1997 ·Trends in Microbiology ·Charles W. Ford,Judith C. Hamel,Douglas Stapert,(unknown),Douglas K. Hutchinson,Michael R. Barbachyn,Gary E. Zurenko	56
15	Identification of a Novel Oxazolidinone (U-100480) with Potent Antimycobacterial Activity 1996 ·Journal of Medicinal Chemistry ·Michael R. Barbachyn,Douglas K. Hutchinson,Steven J. Brickner,Michael H. Cynamon,J O Kilburn,S P Klemens,Suzanne E. Glickman,Kevin C. Grega,Susan K. Hendges,Dana S. Toops,Charles W. Ford,Gary E. Zurenko	193
16	Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections 1996 ·Journal of Medicinal Chemistry ·Steven J. Brickner,Douglas K. Hutchinson,Michael R. Barbachyn,Peter R. Manninen,(unknown),Stuart A. Garmon,Kevin C. Grega,Susan K. Hendges,Dana S. Toops,Charles W. Ford,Gary E. Zurenko	489
17	Regioselective Metalation of Fluoroanilines. An Application to the Synthesis of Fluorinated Oxazolidinone Antibacterial Agents 1995 ·The Journal of Organic Chemistry ·Kevin C. Grega,Michael R. Barbachyn,Steven J. Brickner,S. A. MIZSAK	37
18	An approach to the synthesis of carbon-carbon linked disaccharides 1984 ·The Journal of Organic Chemistry ·Samuel J. Danishefsky,Clarence J. Maring,Michael R. Barbachyn,Brigitte E. Segmüller	23
19	.beta.-Hydroxysulfoximine-directed Simmons-Smith cyclopropanations. Synthesis of (-)- and (+)-thujopsene 1982 ·Journal of the American Chemical Society ·Carl R. Johnson,Michael R. Barbachyn	18
20	Proton affinity, ionization energy, and the nature of frontier orbital electron density 1979 ·Journal of the American Chemical Society ·Roger L. DeKock,Michael R. Barbachyn	21

About Michael R. Barbachyn

Michael R. Barbachyn is a scholar working on Molecular Medicine, Organic Chemistry and Infectious Diseases, having authored 38 papers that have together received 3.7k indexed citations. Recurring topics across this work include Phenothiazines and Benzothiazines Synthesis and Activities (9 papers), Synthesis and Catalytic Reactions (8 papers) and Microbial Natural Products and Biosynthesis (7 papers). The work is most often cited by research in Molecular Medicine (409 citations), Process Chemistry and Technology (227 citations) and Organic Chemistry (2.1k citations). Michael R. Barbachyn has collaborated with scholars based in United States, Netherlands and France. Frequent co-authors include Charles W. Ford, Douglas K. Hutchinson, Gary E. Zurenko, Steven J. Brickner, Kevin C. Grega, Karen Joy Shaw, Betty H. Yagi, Ronda D. Schaadt, Peter R. Manninen and Stuart A. Garmon. Their work appears in journals such as Journal of the American Chemical Society, Angewandte Chemie International Edition and Nature Communications.

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