Michael H. Hecht

8.1k citations

104 papers · 6.5k indexed · 2 hit papers · h-index 44

Impact in

Molecular Biology top 1%
- Protein Structure and Dynamics
- RNA and protein synthesis mechanisms
- Chemical Synthesis and Analysis
- Glycosylation and Glycoproteins Research
Biomaterials top 1%
- Supramolecular Self-Assembly in Materials

Papers in

Molecular Biology 87
- Protein Structure and Dynamics 40
- RNA and protein synthesis mechanisms 23
- Chemical Synthesis and Analysis 17
- Glycosylation and Glycoproteins Research 16
Biomaterials 10

Co-authors: Satwik Kamtekar Robert T. Sauer W. Ray Kim Weixun Wang Jarad Schiffer Jennifer M. Babik Huayu Xiong Yinan Wei
Journals: Proceedings of the National Academy of Sciences (12 papers)Protein Science (11 papers)Journal of the American Chemical Society (9 papers)Journal of Molecular Biology (5 papers)Science (4 papers)
Partner nations: United States Japan United Kingdom

In The Last Decade

Michael H. Hecht

102 papers receiving 6.4k citations

Hit Papers

align trajectories log scale

Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions 2011 · 541 citations

Peers

Countries citing papers authored by Michael H. Hecht

Since Specialization

Citations

This map shows the geographic impact of Michael H. Hecht's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael H. Hecht with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael H. Hecht more than expected).

Fields of papers citing papers by Michael H. Hecht

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael H. Hecht. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael H. Hecht. The network helps show where Michael H. Hecht may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Michael H. Hecht, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael H. Hecht Line = papers co-authored together Michael H. Hecht links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	De Novo Proteins Template the Formation of Semiconductor Quantum Dots ACS Central Science ·Kin Ling Tse, Jing‐Yun Wu, Emile Brunner, Nurul Awainah, João Bertolino, Guangming Cheng, Nan Yao, Gregory D. Scholes, Michael H. Hecht, G. S. Jolly	2025	0
2	Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins Nature Chemistry ·Takesi Fukuzawa, Michael S. Wang, H. Kim, H. Adrian Bunzel, Mi-Ryeong Sim, Florian Hollfelder, Michael H. Hecht	2024	6
3	Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4 Proceedings of the National Academy of Sciences ·史生川原, Koji Umezawa, Le Trong Hoa, Pierre Caussat, A.V. Prokhotskij, Michael H. Hecht, Ryoichi Arai	2023	4
4	A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli Nature Chemical Biology ·Le Trong Hoa, Grant S. Murphy, Katherine M. Digianantonio, Michael H. Hecht	2018	42
5	Artificial Gene Amplification in Escherichia coli Reveals Numerous Determinants for Resistance to Metal Toxicity Journal of Molecular Evolution ·M. Inoue, Michael H. Hecht	2018	7
6	A protein constructed de novo enables cell growth by altering gene regulation Proceedings of the National Academy of Sciences ·Katherine M. Digianantonio, Michael H. Hecht	2016	32
7	Novel proteins: from fold to function Current Opinion in Chemical Biology ·Егор В. Голованов, Michael H. Hecht	2011	50
8	Perchlorate Found by Phoenix Could Provide a Mobile Brine Sludge at the Bed of Mars Northern Ice Cap that Would Allow Flow with Very Low Basal Temperatures: Possible Mechanism for Water Table Re-Charge LPI ·David Fisher, Michael H. Hecht, Samuel P. Kounaves, David C. Catling	2009	5
9	Cofactor binding and enzymatic activity in an unevolved superfamily of de novo designed 4‐helix bundle proteins Protein Science ·Iris Wiitakorpi, Luke H. Bradley, Sayuri P. Jinadasa, Michael H. Hecht	2009	69
10	Structure and dynamics of de novo proteins from a designed superfamily of 4‐helix bundles Protein Science ·Mariola Dragan, Seho Kim, Jean Baum, Michael H. Hecht	2008	42
11	Protein Design by Binary Patterning of Polar and Nonpolar Amino Acids Humana Press eBooks ·Luke H. Bradley, Yinan Wei, Sadegh Ataee, Christine Wurth, Michael H. Hecht	2006	15
12	Ab initio prediction of the three‐dimensional structure of a de novo designed protein: A double‐blind case study Proteins Structure Function and Bioinformatics ·John L. Klepeis, Yinan Wei, Michael H. Hecht, Christodoulos A. Floudas	2004	44
13	Stably folded de novo proteins from a designed combinatorial library Protein Science ·Yinan Wei, Tun Liu, Stephen L. Sazinsky, David A. Moffet, István Pelczer, Michael H. Hecht	2003	84
14	Nature disfavors sequences of alternating polar and non-polar amino acids: implications for amyloidogenesis 1 1Edited by F. E. Cohen Journal of Molecular Biology ·Lalu Suryadi S, Michael H. Hecht	2000	136
15	Heme binding in a library of de Novo designed α-helical binary code proteins He He, Satwik Kamtekar, Claire Simons, Jeremy E. McLean, Michael H. Hecht	1997	1
16	Collection's of de Novo beta-sheet proteins designed by binary patterning of polar and nonpolar amino acids Michael W. West, James R. Beasley, Michael H. Hecht	1997	1
17	De novo heme proteins from designed combinatorial libraries Protein Science ·Michael H. Hecht, Kathleen M. Vogel, Thomas G. Spiro, He He, Satwik Kamtekar, DAVID KENDALL, Jeremy E. McLean, Ramy Farid	1997	81
18	Sequence replacements in the central β‐turn of plastocyanin Protein Science ·Joel A. Ybe, Michael H. Hecht	1996	32
19	Protein Design by Binary Patterning of Polar and Nonpolar Amino Acids Science ·Satwik Kamtekar, Jarad Schiffer, Huayu Xiong, Jennifer M. Babik, Michael H. Hecht Hit paper breakdown →	1993	603
20	Phage lambda repressor revertants Journal of Molecular Biology ·Michael H. Hecht, Robert T. Sauer	1985	46

About Michael H. Hecht

Michael H. Hecht is a scholar working on Molecular Biology, Biomaterials, Radiology, Nuclear Medicine and Imaging, Materials Chemistry and Computational Theory and Mathematics, having authored 104 papers that have together received 6.5k indexed citations. Recurring topics across this work include Protein Structure and Dynamics (40 papers), RNA and protein synthesis mechanisms (23 papers), Enzyme Structure and Function (23 papers), Chemical Synthesis and Analysis (17 papers), Glycosylation and Glycoproteins Research (16 papers), Monoclonal and Polyclonal Antibodies Research (15 papers), Alzheimer's disease research and treatments (12 papers) and Bacteriophages and microbial interactions (11 papers). The work is most often cited by research in Molecular Biology (5.3k citations), Biomaterials (728 citations), Physiology (1.1k citations), Cell Biology (571 citations) and Materials Chemistry (1.6k citations). Michael H. Hecht has collaborated with scholars based in United States, Japan and United Kingdom. Frequent co-authors include Satwik Kamtekar, Robert T. Sauer, W. Ray Kim, Weixun Wang, Jarad Schiffer, Jennifer M. Babik, Huayu Xiong, Yinan Wei, Michael W. West and David Richardson. Their work appears in journals such as Proceedings of the National Academy of Sciences, Protein Science, Journal of the American Chemical Society, Journal of Molecular Biology and Science.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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