Melvyn P. Heyes

10.1k citations

144 papers · 7.8k indexed · 1 hit paper · h-index 50

Co-authors: Sanford P. Markey Kuniaki Saito Bonnie J. Quearry Cristian L. Achim Clayton A. Wiley Eugene O. Major Andrew A. Lackner Sheldon Milstien
Topics: Tryptophan and brain disorders (60 papers)HIV Research and Treatment (34 papers)Stress Responses and Cortisol (32 papers)
Cited by: Biological Psychiatry Behavioral Neuroscience Virology
Journals: New England Journal of Medicine Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United States Czechia Japan

In The Last Decade

Melvyn P. Heyes

144 papers receiving 7.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Quinolinic acid in cerebrospinal fluid and serum in HIV‐1 Infection: Relationship to clinical and neurological status

1991 479 citations Melvyn P. Heyes, Bruce J. Brew et al. Annals of Neurology profile →

Peers

Countries citing papers authored by Melvyn P. Heyes

Since Specialization

Citations

This map shows the geographic impact of Melvyn P. Heyes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Melvyn P. Heyes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Melvyn P. Heyes more than expected).

Fields of papers citing papers by Melvyn P. Heyes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Melvyn P. Heyes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Melvyn P. Heyes. The network helps show where Melvyn P. Heyes may publish in the future.

Co-authorship network of co-authors of Melvyn P. Heyes

This figure shows the co-authorship network connecting the top 25 collaborators of Melvyn P. Heyes. A scholar is included among the top collaborators of Melvyn P. Heyes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Melvyn P. Heyes. Melvyn P. Heyes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro 2003 ·Proceedings of the National Academy of Sciences ·Erik C. Gunther,David J. Stone,Robert Gerwien,Patrícia Meira Bento,Melvyn P. Heyes	148
2	U50,488 protection against HIV-1-related neurotoxicity: involvement of quinolinic acid suppression 2000 ·Neuropharmacology ·Chun C. Chao,(unknown),Genya Gekker,James R. Lokensgard,Melvyn P. Heyes,Phillip K. Peterson	33
3	Labeled Kynurenine Pharmacokinetic Modeling Studies in Gerbils 1999 ·Advances in experimental medicine and biology ·Tomoyuki Kita,Melvyn P. Heyes,Paul F. Morrison,S. P. Markey	2
4	Sources of the neurotoxin quinolinic acid in the brain of HIV-1-infected patients and retrovirus-infected macaques 1998 ·The FASEB Journal ·Melvyn P. Heyes,Kuniaki Saito,Andrew A. Lackner,(unknown),Cristian L. Achim,Sanford P. Markey	124
5	Quinolinic Acid Accumulation in Injured Spinal Cord: Time Course, Distribution, and Species Differences between Rat and Guinea Pig 1997 ·Journal of Neurotrauma ·Andrew R. Blight,E. Carwile LeRoy,Melvyn P. Heyes	35
6	Species Heterogeneity Between Gerbils and Rats: Quinolinate Production by Microglia and Astrocytes and Accumulations in Response to Ischemic Brain Injury and Systemic Immune Activation 1997 ·Journal of Neurochemistry ·Melvyn P. Heyes,Kuniaki Saito,(unknown),Margit G. Proescholdt,(unknown),(unknown),(unknown),Martin Proescholdt,(unknown),Kensuke Kawai,(unknown)	75
7	Neurobehavioral Manifestations of Symptomatic HIV-1 Disease in Children: Can Nutritional Factors Play a Role? 1996 ·Journal of Nutrition ·Pim Brouwers,Charles DeCarli,Melvyn P. Heyes,Howard A. Moss,Pamela L. Wolters,Gareth Tudor‐Williams,Lucy Civitello,Philip A. Pizzo	8
8	Quinolinic acid in patients with systemic lupus erythematosus and neuropsychiatric manifestations. 1996 ·PubMed ·Scott A. Vogelgesang,Melvyn P. Heyes,Sterling G. West,Andres Μ. Salazar,P. Sfikakis,Robert N. Lipnick,Gary L. Klipple,George C. Tsokos	32
9	Macrophage Activation Factors in the Brains of AIDS Patients 1996 ·PubMed ·Cristian L. Achim,Eliezer Masliah,Melvyn P. Heyes,(unknown),(unknown),Maria Baldwin,Clayton A. Wiley	11
10	The relationship between plasma and brain quinolinic acid levels and the severity of hepatic encephalopathy 1995 ·Gastroenterology ·Anthony S. Basile,Kuniaki Saito,(unknown),Christopher O. Record,Robin D. Hughes,Phil Harrison,Roger Williams,Yong Li,Melvyn P. Heyes	30
11	Evidence of excitotoxicity in the brain of the ornithine carbamoyltransferase deficient sparse fur mouse 1995 ·Developmental Brain Research ·Michael B. Robinson,Keri J Hopkins,Mark L. Batshaw,BethAnn McLaughlin,Melvyn P. Heyes,Mary Lou Oster‐Granite	35
12	Mechanism of Delayed Increases in Kynurenine Pathway Metabolism in Damaged Brain Regions Following Transient Cerebral Ischemia 1993 ·Journal of Neurochemistry ·Kuniaki Saito,Thaddeus S. Nowak,(unknown),Melvyn P. Heyes	147
13	Kynurenine 3-Hydroxylase in Brain: Species Activity Differences and Effect of Gerbil Cerebral Ischemia 1993 ·Archives of Biochemistry and Biophysics ·Kuniaki Saito,Bonnie J. Quearry,Misato Saito,T Nowak,Sanford P. Markey,Melvyn P. Heyes	32
14	Virus isolation and quinolinic acid in primary and chronic simian immunodeficiency virus infection 1993 ·AIDS ·Elaine Jordan,Melvyn P. Heyes	13
15	Tryptophan metabolism via the kynurenine pathway in patients with the eosinophilia–Myalgia syndrome 1992 ·Arthritis & Rheumatism ·Richard M. Silver,(unknown),Edwin A. Smith,Bonnie J. Quearry,Yadollah Harati,Esther M. Sternberg,Melvyn P. Heyes	30
16	Effects of immune activation on quinolinic acid and neuroactive kynurenines in the mouse 1992 ·Neuroscience ·Kuniaki Saito,Sanford P. Markey,Melvyn P. Heyes	175
17	Quinolinic acid in cerebrospinal fluid and serum in HIV‐1 Infection: Relationship to clinical and neurological statusbreakdown → 1991 ·Annals of Neurology ·Melvyn P. Heyes,Bruce J. Brew,Alex Martin,Richard W. Price,Andres Μ. Salazar,John J. Sidtis,James A. Yergey,M. Maral Mouradian,(unknown),John G. Keilp,David R. Rubinow,Sanford P. Markey	479
18	Quantification of kynurenic acid in cerebrospinal fluid: effects of systemic and central l-kynurenine administration 1990 ·Journal of Chromatography B Biomedical Sciences and Applications ·Melvyn P. Heyes,Bonnie J. Quearry	48
19	Systemic endotoxin increasesl-tryptophan, 5-hydroxyindoleacetic acid, 3-hydroxykynurenine and quinolinic acid content of mouse cerebral cortex 1989 ·Brain Research ·Melvyn P. Heyes,Bonnie J. Quearry,Sanford P. Markey	69
20	Quantification of quinolinic acid in rat brain, whole blood, and plasma by gas chromatography and negative chemical ionization mass spectrometry: Effects of systemic l-tryptophan administration on brain and blood quinolinic acid concentrations 1988 ·Analytical Biochemistry ·Melvyn P. Heyes,Sanford P. Markey	118

About Melvyn P. Heyes

Melvyn P. Heyes is a scholar working on Biological Psychiatry, Behavioral Neuroscience and Virology, having authored 144 papers that have together received 7.8k indexed citations. Recurring topics across this work include Tryptophan and brain disorders (60 papers), HIV Research and Treatment (34 papers) and Stress Responses and Cortisol (32 papers). The work is most often cited by research in Biological Psychiatry (3.5k citations), Behavioral Neuroscience (2.1k citations) and Virology (1.4k citations). Melvyn P. Heyes has collaborated with scholars based in United States, Czechia and Japan. Frequent co-authors include Sanford P. Markey, Kuniaki Saito, Kuniaki Saito, Bonnie J. Quearry, Cristian L. Achim, Clayton A. Wiley, Eugene O. Major, Andrew A. Lackner, Sheldon Milstien and Paul F. Morrison. Their work appears in journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact