Massimo Spada

5.4k total citations · 2 hit papers
58 papers, 4.1k citations indexed

About

Massimo Spada is a scholar working on Immunology, Molecular Biology and Virology. According to data from OpenAlex, Massimo Spada has authored 58 papers receiving a total of 4.1k indexed citations (citations by other indexed papers that have themselves been cited), including 32 papers in Immunology, 17 papers in Molecular Biology and 14 papers in Virology. Recurrent topics in Massimo Spada's work include Immunotherapy and Immune Responses (19 papers), Immune Cell Function and Interaction (17 papers) and HIV Research and Treatment (14 papers). Massimo Spada is often cited by papers focused on Immunotherapy and Immune Responses (19 papers), Immune Cell Function and Interaction (17 papers) and HIV Research and Treatment (14 papers). Massimo Spada collaborates with scholars based in Italy, United States and United Kingdom. Massimo Spada's co-authors include Filippo Belardelli, Mariantonia Logozzi, Caterina Lapenta, Stefano M. Santini, Stefano Fais, Stefania Parlato, Tiziana Di Pucchio, Francesco Lozupone, Cristina Federici and Luana Lugini and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Journal of Experimental Medicine and SHILAP Revista de lepidopterología.

In The Last Decade

Massimo Spada

56 papers receiving 4.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

2009 776 citations Mariantonia Logozzi, Angelo De Milito et al. PLoS ONE profile →
Type I Interferon as a Powerful Adjuvant for Monocyte-Derived Dendritic Cell Development and Activity in Vitro and in Hu-Pbl-Scid Mice

2000 535 citations Stefano M. Santini, Caterina Lapenta et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Massimo Spada Italy	32	1.9k	1.8k	812	761	439	58	4.1k
Santos Mañes Spain	46	3.2k 1.7×	2.5k 1.4×	1.7k 2.1×	881 1.2×	413 0.9×	88	6.9k
Nisha Nagarsheth United States	12	2.3k 1.2×	1.8k 1.0×	2.4k 3.0×	644 0.8×	360 0.8×	16	4.8k
Thomas Kieber‐Emmons United States	39	2.6k 1.4×	1.5k 0.9×	568 0.7×	332 0.4×	311 0.7×	175	4.6k
Avi Ashkenazi United States	26	2.3k 1.2×	2.4k 1.4×	761 0.9×	813 1.1×	472 1.1×	37	4.3k
Tri Giang Phan Australia	37	1.4k 0.8×	3.7k 2.0×	946 1.2×	334 0.4×	412 0.9×	66	5.9k
Pablo Sarobe Spain	39	1.5k 0.8×	2.6k 1.5×	2.0k 2.4×	525 0.7×	935 2.1×	125	5.5k
Bruno Sáinz Spain	39	2.0k 1.1×	964 0.5×	1.7k 2.1×	1.1k 1.4×	1.1k 2.5×	88	4.7k
Lei Jin China	39	1.7k 0.9×	3.4k 1.9×	894 1.1×	485 0.6×	889 2.0×	121	5.3k
Rosa Ana Lacalle Spain	30	2.1k 1.1×	1.2k 0.7×	739 0.9×	448 0.6×	238 0.5×	40	3.9k

Countries citing papers authored by Massimo Spada

Since Specialization

Citations

This map shows the geographic impact of Massimo Spada's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Massimo Spada with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Massimo Spada more than expected).

Fields of papers citing papers by Massimo Spada

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Massimo Spada. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Massimo Spada. The network helps show where Massimo Spada may publish in the future.

Co-authorship network of co-authors of Massimo Spada

This figure shows the co-authorship network connecting the top 25 collaborators of Massimo Spada. A scholar is included among the top collaborators of Massimo Spada based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Massimo Spada. Massimo Spada is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Gambardella, Adriana Rosa, Carlo Curcio, Adele De Ninno, et al.. (2025). Decitabine co-operates with the IL-33/ST2 axis modifying the tumor microenvironment and improving the response to PD-1 blockade in melanoma. Journal of Experimental & Clinical Cancer Research. 44(1). 137–137. 2 indexed citations

Lapenta, Caterina, Stefano M. Santini, Simona Donati, et al.. (2024). Anti-Tumor Immunity to Patient-Derived Breast Cancer Cells by Vaccination with Interferon-Alpha-Conditioned Dendritic Cells (IFN-DC). Vaccines. 12(9). 1058–1058.

Raimo, Rossella Di, Davide Mizzoni, Massimo Spada, et al.. (2023). Oral Treatment with Plant-Derived Exosomes Restores Redox Balance in H2O2-Treated Mice. Antioxidants. 12(6). 1169–1169. 32 indexed citations

Ferrantelli, Flavia, Francesco Manfredi, Chiara Chiozzini, et al.. (2023). SARS-CoV-2-Specific CD8+ T-Cells in Blood but Not in the Lungs of Vaccinated K18-hACE2 Mice after Infection. Vaccines. 11(9). 1433–1433. 1 indexed citations

Luca, Gabriele De, Laura Chronopoulou, Francesca Pedini, et al.. (2023). MiR126-targeted-nanoparticles combined with PI3K/AKT inhibitor as a new strategy to overcome melanoma resistance. Molecular Therapy. 32(1). 152–167. 9 indexed citations

Angelis, Maria Laura De, Federica Francescangeli, Chiara Nicolazzo, et al.. (2022). An organoid model of colorectal circulating tumor cells with stem cell features, hybrid EMT state and distinctive therapy response profile. Journal of Experimental & Clinical Cancer Research. 41(1). 86–86. 48 indexed citations

Lapenta, Caterina, Simona Donati, Francesca Spadaro, et al.. (2019). Lenalidomide improves the therapeutic effect of an interferon-α-dendritic cell-based lymphoma vaccine. Cancer Immunology Immunotherapy. 68(11). 1791–1804. 20 indexed citations

Michelini, Zuleika, Donatella Negri, Mirella Biava, et al.. (2014). Murine Granulocyte–Macrophage Colony-Stimulating Factor Expressed from a Bicistronic Simian Immunodeficiency Virus-Based Integrase-Defective Lentiviral Vector Does Not Enhance T-Cell Responses in Mice. Viral Immunology. 27(10). 512–520.

Rossi, Alessandra, Zuleika Michelini, Pasqualina Leone, et al.. (2014). Optimization of Mucosal Responses after Intramuscular Immunization with Integrase Defective Lentiviral Vector. PLoS ONE. 9(9). e107377–e107377. 11 indexed citations

10.

Michelini, Zuleika, Donatella Negri, Silvia Baroncelli, et al.. (2009). Development and use of SIV-based Integrase defective lentiviral vector for immunization. Vaccine. 27(34). 4622–4629. 33 indexed citations

11.

SAU, A. C., Silvia Pezzola, Cristina Geroni, et al.. (2009). In vitro and in vivo efficacy of 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) on human melanoma. European Journal of Cancer. 45(14). 2606–2617. 31 indexed citations

12.

Giammarioli, Anna Maria, Angela Maselli, Andrea Casagrande, et al.. (2008). Pyrimethamine Induces Apoptosis of Melanoma Cells via a Caspase and Cathepsin Double-Edged Mechanism. Cancer Research. 68(13). 5291–5300. 36 indexed citations

13.

Milito, Angelo De, Elisabetta Iessi, Mariantonia Logozzi, et al.. (2007). Proton Pump Inhibitors Induce Apoptosis of Human B-Cell Tumors through a Caspase-Independent Mechanism Involving Reactive Oxygen Species. Cancer Research. 67(11). 5408–5417. 242 indexed citations

14.

Negri, Donatella, Zuleika Michelini, Silvia Baroncelli, et al.. (2007). Successful Immunization with a Single Injection of Non-integrating Lentiviral Vector. Molecular Therapy. 15(9). 1716–1723. 66 indexed citations

15.

Bracci, Laura, Irene Canini, Massimo Venditti, et al.. (2005). Type I IFN as a vaccine adjuvant for both systemic and mucosal vaccination against influenza virus. Vaccine. 24. S56–S57. 36 indexed citations

16.

Luciani, Francesca, Massimo Spada, Angelo De Milito, et al.. (2004). Effect of Proton Pump Inhibitor Pretreatment on Resistance of Solid Tumors to Cytotoxic Drugs. JNCI Journal of the National Cancer Institute. 96(22). 1702–1713. 345 indexed citations

17.

Santodonato, Laura, Giuseppina D’Agostino, Roberto Nisini, et al.. (2003). Monocyte-Derived Dendritic Cells Generated After a Short-Term Culture with IFN-α and Granulocyte-Macrophage Colony-Stimulating Factor Stimulate a Potent Epstein-Barr Virus-Specific CD8+ T Cell Response. The Journal of Immunology. 170(10). 5195–5202. 63 indexed citations

18.

Fabio, Simonetta Di, Jens Van Roey, Giacomo Giannini, et al.. (2003). Inhibition of vaginal transmission of HIV-1 in hu-SCID mice by the non-nucleoside reverse transcriptase inhibitor TMC120 in a gel formulation. AIDS. 17(11). 1597–1604. 98 indexed citations

19.

Fabio, Simonetta Di, Giacomo Giannini, Caterina Lapenta, et al.. (2001). Vaginal transmission of HIV-1 in hu-SCID mice: a new model for the evaluation of vaginal microbicides. AIDS. 15(17). 2231–2238. 37 indexed citations

20.

Lapenta, Caterina, Stefano M. Santini, Enrico Proietti, et al.. (1999). Type I Interferon Is a Powerful Inhibitor of in Vivo HIV-1 Infection and Preserves Human CD4+ T Cells from Virus-Induced Depletion in SCID Mice Transplanted with Human Cells. Virology. 263(1). 78–88. 42 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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