Massimo Spada

5.4k citations

58 papers · 4.1k indexed · 2 hit papers · h-index 32

Impact in

Virology top 2%
- HIV Research and Treatment
Immunology top 1%
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immune Response and Inflammation

Papers in ⓘ

Virology 14
- HIV Research and Treatment 14
Immunology 32
- Immunotherapy and Immune Responses 19
- Immune Cell Function and Interaction 17
- T-cell and B-cell Immunology 8

Co-authors: Filippo Belardelli (28 shared papers)Mariantonia Logozzi (17 shared papers)Caterina Lapenta (18 shared papers)Stefano M. Santini (14 shared papers)Stefano Fais (17 shared papers)Stefania Parlato (12 shared papers)Tiziana Di Pucchio (3 shared papers)Luana Lugini (6 shared papers)
Journals: Journal of Virology (4 papers)Vaccine (3 papers)Cancer Research (3 papers)Journal of Experimental & Clinical Cancer Research (3 papers)The Journal of Experimental Medicine (2 papers)
Partner nations: Italy United States United Kingdom

In The Last Decade

Massimo Spada

56 papers receiving 4.0k citations

Hit Papers

align trajectories log scale

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients 2009 · 776 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2009 PLoS ONE
2000 The Journal of Experimental Medicine

Peers

Countries citing papers authored by Massimo Spada

Since Specialization

Citations

This map shows the geographic impact of Massimo Spada's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Massimo Spada with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Massimo Spada more than expected).

Fields of papers citing papers by Massimo Spada

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Massimo Spada. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Massimo Spada. The network helps show where Massimo Spada may publish in the future.

Co-authors

The 25 scholars most cited alongside Massimo Spada, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Massimo Spada Line = papers co-authored together Massimo Spada links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 58 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients PLoS ONE ·Mariantonia Logozzi, Angelo De Milito, Luana Lugini, Martina Borghi, Luana Calabrò, Massimo Spada, Maurizio Perdicchio, Maria Lucia Marino, Cristina Federici, Elisabetta Iessi, Daria Brambilla, Giulietta Venturi, Francesco Lozupone, Mario Santinami, Veronica Huber, Michele Maio, Licia Rivoltini, Stefano Fais Hit paper breakdown →	2009	776
2	Type I Interferon as a Powerful Adjuvant for Monocyte-Derived Dendritic Cell Development and Activity in Vitro and in Hu-Pbl-Scid Mice The Journal of Experimental Medicine ·Stefano M. Santini, Caterina Lapenta, Mariantonia Logozzi, Stefania Parlato, Massimo Spada, Tiziana Di Pucchio, Filippo Belardelli Hit paper breakdown →	2000	535
3	Effect of Proton Pump Inhibitor Pretreatment on Resistance of Solid Tumors to Cytotoxic Drugs JNCI Journal of the National Cancer Institute ·Francesca Luciani, Massimo Spada, Angelo De Milito, Agnese Molinari, Licia Rivoltini, Annalisa Montinaro, Manuela Marra, Luana Lugini, Mariantonia Logozzi, Francesco Lozupone, Cristina Federici, Elisabetta Iessi, Giorgio Parmiani, Giuseppe Arancia, Filippo Belardelli, Stefano Fais	2004	345
4	Proton Pump Inhibitors Induce Apoptosis of Human B-Cell Tumors through a Caspase-Independent Mechanism Involving Reactive Oxygen Species Cancer Research ·Angelo De Milito, Elisabetta Iessi, Mariantonia Logozzi, Francesco Lozupone, Massimo Spada, Maria Lucia Marino, Cristina Federici, Maurizio Perdicchio, Paola Matarrese, Luana Lugini, Anna Nilsson, Stefano Fais	2007	242
5	Expression of CCR-7, MIP-3β, and Th-1 chemokines in type I IFN-induced monocyte-derived dendritic cells: importance for the rapid acquisition of potent migratory and functional activities Blood ·Stefania Parlato, Stefano M. Santini, Caterina Lapenta, Tiziana Di Pucchio, Mariantonia Logozzi, Massimo Spada, Anna Maria Giammarioli, Walter Malorni, Stefano Fais, Filippo Belardelli	2001	218
6	IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils OncoImmunology ·Valeria Lucarini, Giovanna Ziccheddu, Iole Macchia, Valentina La Sorsa, Francesca Peschiaroli, Carla Buccione, Antonella Sistigu, Massimo Sanchez, Sara Andreone, Maria Teresa D’Urso, Massimo Spada, Daniele Macchia, Claudia Afferni, Fabrizio Mattei, Giovanna Schiavoni	2017	152
7	Chimeric Plant Virus Particles as Immunogens for Inducing Murine and Human Immune Responses against Human Immunodeficiency Virus Type 1 Journal of Virology ·Carla Marusic, Paola Rizza, Laura Lattanzi, Camillo Mancini, Massimo Spada, Filippo Belardelli, Eugenio Benvenuto, Imerio Capone	2001	140
8	IFN‐α‐conditioned dendritic cells are highly efficient in inducing cross‐priming CD8⁺ T cells against exogenous viral antigens European Journal of Immunology ·Caterina Lapenta, Stefano M. Santini, Massimo Spada, Simona Donati, Francesca Urbani, Daniele Accapezzato, Debora Franceschini, Mauro Andreotti, Vincenzo Barnaba, Filippo Belardelli	2006	119
9	Type I IFNs Control Antigen Retention and Survival of CD8α+ Dendritic Cells after Uptake of Tumor Apoptotic Cells Leading to Cross-Priming The Journal of Immunology ·Silvia Lorenzi, Fabrizio Mattei, Antonella Sistigu, Laura Bracci, Francesca Spadaro, Massimo Sanchez, Massimo Spada, Filippo Belardelli, Lucia Gabriele, Giovanna Schiavoni	2011	117
10	Potent Immune Response against HIV-1 and Protection from Virus Challenge in hu-PBL-SCID Mice Immunized with Inactivated Virus-pulsed Dendritic Cells Generated in the Presence of IFN-α The Journal of Experimental Medicine ·Caterina Lapenta, Stefano M. Santini, Mariantonia Logozzi, Massimo Spada, Mauro Andreotti, Tiziana Di Pucchio, Stefania Parlato, Filippo Belardelli	2003	106
11	Inhibition of vaginal transmission of HIV-1 in hu-SCID mice by the non-nucleoside reverse transcriptase inhibitor TMC120 in a gel formulation AIDS ·Simonetta Di Fabio, Jens Van Roey, Giacomo Giannini, Guy Van den Mooter, Massimo Spada, Andrea Binelli, Maria Franca Pirillo, Elena Germinario, Filippo Belardelli, Marie‐Pierre de Béthune, Stefano Vella	2003	98
12	Type I IFN is a powerful mucosal adjuvant for a selective intranasal vaccination against influenza virus in mice and affects antigen capture at mucosal level Vaccine ·Laura Bracci, Irene Canini, Simona Puzelli, Paola Sestili, Massimo Venditti, Massimo Spada, Isabella Donatelli, Filippo Belardelli, Enrico Proietti	2005	79
13	Effect Of Human Natural Killer and γδ T Cells on the Growth of Human Autologous Melanoma Xenografts in SCID Mice Cancer Research ·Francesco Lozupone, Daniela Pende, Vito L. Burgio, Chiara Castelli, Massimo Spada, Massimo Venditti, Francesca Luciani, Luana Lugini, Cristina Federici, Carlo Ramoni, Licia Rivoltini, Giorgio Parmiani, Filippo Belardelli, Paola Rivera, Stefania Marcenaro, Lorenzo Moretta, Stefano Fais	2004	76
14	Successful Immunization with a Single Injection of Non-integrating Lentiviral Vector Molecular Therapy ·Donatella Negri, Zuleika Michelini, Silvia Baroncelli, Massimo Spada, Silvia Vendetti, Viviana Buffa, Roberta Bona, Pasqualina Leone, Mary E. Klotman, Andrea Cara	2007	66
15	Monocyte-Derived Dendritic Cells Generated After a Short-Term Culture with IFN-α and Granulocyte-Macrophage Colony-Stimulating Factor Stimulate a Potent Epstein-Barr Virus-Specific CD8+ T Cell Response The Journal of Immunology ·Laura Santodonato, Giuseppina D’Agostino, Roberto Nisini, Sabrina Mariotti, Domenica M. Monque, Massimo Spada, Laura Lattanzi, Maria Paola Perrone, Mauro Andreotti, Filippo Belardelli, Maria Ferrantini	2003	63
16	Inhibition of human immunodeficiency virus (HIV-1) infection in human peripheral blood leucocytes-SCID reconstituted mice by rapamycin Clinical & Experimental Immunology ·Ferdinando Nicoletti, C Lamenta, Simona Donati, Massimo Spada, Alessandro Ranazzi, Bruno Cacopardo, Katia Mangano, Filippo Belardelli, Carlo Federico Perno, Stefano Aquaro	2008	51
17	An organoid model of colorectal circulating tumor cells with stem cell features, hybrid EMT state and distinctive therapy response profile Journal of Experimental & Clinical Cancer Research ·Maria Laura De Angelis, Federica Francescangeli, Chiara Nicolazzo, Michele Signore, Alessandro Giuliani, Lidia Colace, Alessandra Boe, Valentina Magri, Marta Baiocchi, Antonio Ciardi, Francesco Scarola, Massimo Spada, Filippo La Torre, Paola Gazzaniga, Mauro Biffoni, Ruggero De Maria, Ann Zeuner	2022	48
18	A multidisciplinary study usingin vivotumor models and microfluidic cell-on-chip approach to explore the cross-talk between cancer and immune cells Journal of Immunotoxicology ·Fabrizio Mattei, Giovanna Schiavoni, Adele De Ninno, Valeria Lucarini, Paola Sestili, Antonella Sistigu, Alessandra Fragale, Massimo Sanchez, Massimo Spada, Annamaria Gerardino, Filippo Belardelli, Luca Businaro, Lucia Gabriele	2014	48
19	IRF-8 Controls Melanoma Progression by Regulating the Cross Talk between Cancer and Immune Cells within the Tumor Microenvironment Neoplasia ·Fabrizio Mattei, Giovanna Schiavoni, Paola Sestili, Francesca Spadaro, Alessandra Fragale, Antonella Sistigu, Valeria Lucarini, Massimo Spada, Massimo Sanchez, Stefania Scala, Angela Battistini, Filippo Belardelli, Lucia Gabriele	2012	44
20	Type I Interferon Is a Powerful Inhibitor of in Vivo HIV-1 Infection and Preserves Human CD4+ T Cells from Virus-Induced Depletion in SCID Mice Transplanted with Human Cells Virology ·Caterina Lapenta, Stefano M. Santini, Enrico Proietti, Paola Rizza, Mariantonia Logozzi, Massimo Spada, Stefania Parlato, Stefano Fais, Paula M. Pitha, Filippo Belardelli	1999	42

About Massimo Spada

Massimo Spada is a scholar working on Virology, Immunology, Infectious Diseases, Aging and Oncology, having authored 58 papers that have together received 4.1k indexed citations. Recurring topics across this work include Immunotherapy and Immune Responses (19 papers), Immune Cell Function and Interaction (17 papers), HIV Research and Treatment (14 papers), T-cell and B-cell Immunology (8 papers), Virus-based gene therapy research (6 papers), Extracellular vesicles in disease (5 papers), HIV/AIDS Research and Interventions (4 papers) and Cancer Cells and Metastasis (3 papers). The work is most often cited by research in Virology (411 citations), Immunology (1.8k citations), Cancer Research (761 citations), Oncology (812 citations) and Molecular Biology (1.9k citations). Massimo Spada has collaborated with scholars based in Italy, United States and United Kingdom. Frequent co-authors include Filippo Belardelli, Mariantonia Logozzi, Caterina Lapenta, Stefano M. Santini, Stefano Fais, Stefania Parlato, Tiziana Di Pucchio, Luana Lugini, Cristina Federici and Francesco Lozupone. Their work appears in journals such as Journal of Virology, Vaccine, Cancer Research, Journal of Experimental & Clinical Cancer Research and The Journal of Experimental Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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